Human Bone Marrow Contains Mesenchymal Stromal Stem Cells That Differentiate In Vitro into Contractile Myofibroblasts Controlling T Lymphocyte Proliferation by Yves Lecarpentier, Olivier Schussler, Antonija Sakic, José Maria Rincon-Garriz, Priscilla Soulie, Marie-Luce Bochaton-Piallat, Vincent Kindler

“…Here we show that medullar MSC cultured in 2D formed an adherent stroma of cells expressing well-organized microfilaments containing α-smooth muscle actin and nonmuscle myosin heavy chain IIA. …”
Get full text

Machine Learning Models for Spring Discharge Forecasting by Francesco Granata, Michele Saroli, Giovanni de Marinis, Rudy Gargano

Get full text

Stabilizing milk-derived extracellular vesicles (mEVs) through lyophilization: a novel trehalose and tryptophan formulation for maintaining structure and Bioactivity during long-te... by Alan B. Dogan, Spencer R. Marsh, Rachel J. Tschetter, Claire E. Beard, Md R. Amin, L. Jane Jourdan, Robert G. Gourdie

Get full text

Effect of rennet on buffalo cheese microbiota, taste and flavor by Angela M. I. Montone, Angelo Citro, Germana Colarusso, Francesca Garofalo, Rubina Paradiso, Giorgia Borriello, Domenico Vecchio, Federico Capuano

Get full text

Identifying Factors for Low-Risk Participation in Alternative Cardiac Rehabilitation Models for Patients with Coronary Heart Disease Using MI’S SCOREPAD by Eric J. Brandt, Joshua Garfein, Chih-Wen Pai, Joseph Bryant, Eva Kline-Rogers, Samantha Fink, Melvyn Rubenfire

“…Low-risk factors included not having any of the following: metabolic syndrome, presence of implantable cardioverter defibrillator or permanent pacemaker, active smoking, prior stroke, congestive heart failure, obesity, advanced renal disease, poor exercise capacity, peripheral arterial disease, angina, or clinical depression (MI’S SCOREPAD). …”
Get full text

Severe immunodeficiency spectrum associated with NHEJ1 gene mutation: Cernunnos/XLF deficiency by Ana María Navarro, Gabriela Mantilla, Jorge Andrés Fernández, Mario Fernando Unigarro, Alfonso Suárez, María Claudia Ortega

“…This gene participates in the DNA non-homologous end-joining pathway, repairing double-strand breaks in the DNA of mammalian cells. The clinical features include growth retardation, microcephaly, triangle-shaped face, recurrent infections, fibroblast’s excessive sensitivity to gamma-ionizing radiation, and hypogammaglobulinemia; also, low counts of subpopulations of B and T lymphocytes, with normal values of natural-killer cells. …”
Get full text

Temporal–Spatial Acupuncture Effects on Poststroke Sensorimotor Cortex via Yanglingquan (GB34) by Ruoyi Liu, Yue Wang, Myadagbadam Boldbayar, Yuanyuan Li, Chen Chen, Xin Yu, Tianjiao Xu, Muzhao Zhang, Yihuai Zou, Hua Zhang

“…Hemiplegia is a common symptom after a stroke, and acupuncture at Yanglingquan (GB34) has been found to play a significant role in the treatment of poststroke hemiplegia. …”
Get full text

A Case of Diffuse Leptomeningeal Glioneuronal Tumor Misdiagnosed as Chronic Tuberculous Meningitis without Brain Biopsy by Jung-goo Lee, Hak-cheol Ko, Jin-gyu Choi, Youn Soo Lee, Byung-chul Son

“…An additional course of antituberculosis medication with steroid was started without biopsy of the brain. Laboratory examinations for tuberculosis were negative again. …”
Get full text

Use of Extracorporeal Membrane Oxygenation in Pneumocystis Pneumonia of an Infant with AIDS by Grégoire Cane, Arnaud De Boislambert, Charlotte Sgro, Pierre Lavedan, Hélène Foulgoc, Nadir Tafer, Alexandre Ouattara

“…We prescribed combined antiretroviral, antibiotic, and steroid therapy aimed at preventing immune reconstitution inflammatory syndrome. …”
Get full text

Long-Term Follow-Up after Intravenous Immunoglobulin Therapy in Patients with Severe Ocular Mucous Membrane Pemphigoid Unresponsive to Conventional Therapy by Stefania Leuci, Massimo Amato, Elena Calabria, Raffaele Piscopo, Fausto Tranfa, Gianrico Spagnuolo, Michele Davide Mignogna

“…In its most severe forms, this disease needs systemic therapy, usually based on steroids and immunosuppressant agents. In unresponsive cases or in the presence of contraindications or severe side effects due to conventional systemic corticosteroid and/or immunosuppressant therapy, a therapy shift to high-dose intravenous immunoglobulins (IVIg) has been recommended in other reports. …”
Get full text

Inhibition of GSK3β is synthetic lethal with FHIT loss in lung cancer by blocking homologous recombination repair by Shishi Tao, Yue Pu, Eun Ju Yang, Guowen Ren, Changxiang Shi, Li-Jie Chen, Liang Chen, Joong Sup Shim

“…The inhibition of GSK3β in FHIT-deficient cells suppressed the ATR/BRCA1/RAD51 axis in HRR signaling via two distinct pathways and suppressed DNA double-strand break repair, leading to the accumulation of DNA damage and apoptosis. …”
Get full text

Understanding transmission pathways and integrated digital surveillance potential of antimicrobial resistance in Ethiopia in a One Health approach: a mixed-method study protocol by Muhammad Asaduzzaman, Christoph Gradmann, Andrea Sylvia Winkler, Zeleke Mekonnen, Ernst Kristian Rodland

Get full text

The Effect of Sandblast and Plasma Surface Treatment of Titanium Abutment on Tensile Bond Strength with Ultra-translucent Zirconia Crown: A Comparative Study by Amani Abduljabar Altaie, Emad Farhan Alkhalidi

Get full text

Investigating Maternal Perception of Control and Support in the Postpartum Period and Influencing Factors in Childbirth: A Multiple Linear Regression Analysis Model by Tuğba Yazici Topçu, Ruveyde Aydin, Songül Aktaş

“…Design A cross‐sectional design was employed. The STROBE checklist was used. Methods The study was conducted between July 2021 and March 2022 with 400 mothers who were in their first 2 months postpartum and lived in Türkiye. …”
Get full text

Knowledge, Attitude, Practice, and Adherence to Antiretroviral Therapy among People Living with HIV in Nepal by Sweta Shrestha, Subodh Chataut, Badri Kc, Khagendra Acharya, Sait Kumar Pradhan, Sunil Shrestha

Get full text

Rare Case of Gut-associated Lymphoid Tissue Carcinoma in the Sigmoid Colon of a Very Elderly Patient: A Case Report by Kou Kanesada, Kazuhiko Yoshimatsu, Yoshitomo Ito, Shuya Yano, Masaaki Hori, Masaharu Higashida, Toshimasa Okada, Shunji Endo, Yoshinori Fujiwara, Yasuto Fujimoto, Tatsushi Shiomi, Tomio Ueno

“…Lymphocytes, along with lymph follicles, proliferated compressively in the stroma surrounding the tumor glands. Immunohistochemical analysis showed lost expression of mismatch repair proteins, MLH1 and PMS2, consistent with the tumor immunohistochemistry profile. …”
Get full text

Effect of HTST Thermal Treatments on End-Use Quality Characteristics of Goat Milk by B. D. Rohitha Prasantha, K. M. S. Wimalasiri

Get full text

Study on Drug Usage, Storage and Wastage among Households in Chengalpattu, Tamil Nadu, India - A Cross-Sectional Study by Nancy L, Palanivel Sundaram M, Logaraj M, Anantharaman VV, Kalaivanan R

“…In this study Increasing age, Education and Family with senior citizens above 60 years have a strong association with storage condition of medicines at home. …”
Get full text

Raphe-Type Bicuspid Aortic Valve as a Risk Factor for Transcatheter Aortic Valve Replacement Failure: Improving Outcomes Using the LIRA Method and the Medtronic FX Prosthesis by Francesca Napoli, Barbara Bellini, Vittorio Romano, Greca Zanda, Ciro Vella, Filippo Russo, Luca Angelo Ferri, Marco Bruno Ancona, Paolo Bonfanti, Eustachio Agricola, Antonio Esposito, Matteo Montorfano

“…Transcatheter aortic valve replacement (TAVR) in patients with severe aortic stenosis and raphe-type bicuspid aortic valve (BAV) is still associated with poor outcomes in terms of increased risk of paravalvular regurgitation, stroke, and permanent pacemaker implantation. There is no definitive consensus on the optimal sizing method for prosthesis selection in this setting. …”
Get full text

Stem Cells and Regenerative Medicine: Myth or Reality of the 21th Century by J.-F. Stoltz, N. de Isla, Y. P. Li, D. Bensoussan, L. Zhang, C. Huselstein, Y. Chen, V. Decot, J. Magdalou, N. Li, L. Reppel, Y. He

“…Different clinical applications are under study (cardiac insufficiency, atherosclerosis, stroke, bone and cartilage deterioration, diabetes, urology, liver, ophthalmology, and organ’s reconstruction). …”
Get full text