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  1. 3341

    The DNA Polymerase _-Primase Complex: Multiple Functions and Interactions by Marco Muzi-Falconi, Michele Giannattasio, Marco Foiani, Paolo Plevani

    Published 2003-01-01
    “…Because of this peculiarity the major role of the DNA polymerase _-primase complex (pol-prim) is in the initiation of DNA replication at chromosomal origins and in the discontinuous synthesis of Okazaki fragments on the lagging strand of the replication fork. However, pol-prim seems to play additional roles in other complex cellular processes, such as the response to DNA damage, telomere maintenance, and the epigenetic control of higher order chromatin assembly.…”
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  2. 3342

    Design of a 20,000 Pound Variable Stiffness Actuator for Structural Vibration Attenuation by John Leavitt, James E. Bobrow, Faryar Jabbari

    Published 2008-01-01
    “…In order to test the actuator on a full scale structure, an effective spring constant of approximately 10,000 pounds/inch was required over a two inch stroke. Because of the spring-like behavior, rather than damper-like behavior, the actuator does not transmit high forces to a vibrating structure like linear viscous dampers do when velocities are high. …”
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  3. 3343
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    Hypoxia Inducible Factor Pathway and Physiological Adaptation: A Cell Survival Pathway? by Hemant Kumar, Dong-Kug Choi

    Published 2015-01-01
    “…Hypoxia plays a key role in the pathophysiology of heart disease, cancers, stroke, and other causes of mortality. Hypoxia inducible factor(s) (HIFs) are key oxygen sensors that mediate the ability of the cell to cope with decreased oxygen tension. …”
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    Successful Treatment of Genitofemoral Neuralgia Using Ultrasound Guided Injection: A Case Report and Short Review of Literature by Harsha Shanthanna

    Published 2014-01-01
    “…As a therapeutic procedure, it was injected with local anesthetic and steroid using ultrasound guidance. The initial injection led to pain relief of 3 months. …”
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    Up-to-Date Tailored Systemic Treatment in Pancreatic Ductal Adenocarcinoma by Caroline Y. K. Fong, Emma Burke, David Cunningham, Naureen Starling

    Published 2019-01-01
    “…Research has since focussed on understanding the role and interplay between various components of the desmoplastic stroma and tumour microenvironment, in addition to developing targeted therapies based on molecular features to improve the prognosis associated with this malignancy. …”
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  12. 3352
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    Sharing and Cooperation of Improved Cross-Entropy Optimization Algorithm in Telemedicine Multimedia Information Processing by Hongjiao Wu

    Published 2023-01-01
    “…Meanwhile, the system in this paper can help hospitals achieve fast and accurate diagnosis, which has strong theoretical and practical values.…”
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  14. 3354
  15. 3355

    Therapeutic Use of Botulinum Toxin in Neurorehabilitation by Domenico Intiso

    Published 2012-01-01
    “…Its use for the reduction of focal spasticity following stroke, brain injury, and cerebral palsy is provided. …”
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    Ramsay Hunt Syndrome Associated with Central Nervous System Involvement in an Adult by Tommy L. H. Chan, Ana M. Cartagena, Anne Marie Bombassaro, Seyed M. Hosseini-Moghaddam

    Published 2016-01-01
    “…However, cerebellar symptoms did not improve until a tapering course of steroid therapy was initiated.…”
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