Human Serum Albumin and Human Serum Albumin Nanoparticles as Carriers of 10-(2′-Pyrimidyl)-3,6-diazaphenothiazine: In Vitro Spectroscopic Studies by Aleksandra Owczarzy, Karolina Kulig, Beata Morak-Młodawska, Małgorzata Jeleń, Tammam Muhammetoglu, Wojciech Rogóż, Małgorzata Maciążek-Jurczyk

“…Based on the obtained data and the appropriate mathematical models (Stern-Volmer and Klotz models), it can be concluded that 10-Pyr-3,6-DAPT probably forms a weak (K_a = (5.24 ± 0.57) <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>×</mo></mrow></semantics></math></inline-formula> 10⁴ and K_a = (4.67 ± 0.59) <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>×</mo></mrow></semantics></math></inline-formula> 10⁴) for excitation wavelengths λ_ex 275 nm and λ_ex 295 nm, respectively) static complex (k_q > 10¹⁰) with HSA (at Sudlow site II (subdomain IIIA), and the phenomenon of it having both strong therapeutic and toxic effects is possible. …”
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Evaluation of Ecosystem Services and Tradeoff and Synergy in the Alpine and Canyon Region of Southwest China Based on Multi-source Geographic Data by LIU Jing, XIANG Jiayi, ZHANG Donghai, LAN Mengyao, GUAN Yinghui

“…Spatially, carbon sequestration gradually increased from northwest to southeast, while water retention exhibited strong spatial heterogeneity. In contrast, soil retention services was overall deteriorated, decreasing from 263.50 t/(km2·a) to 226.25 t/(km2·a), with a reduction of 27.50% in the northwest Yunnan alpine canyon ecological maintenance zone. (2) The proportion of the area of ecosystem service hotspot areas increased by 5.41%, following a distribution pattern of the first-class hotspot areas > the non-hot spot areas > the second-class hotspot areas > the third-class hotspot areas form 2000 to 2020. (3) Carbon sequestration services exhibited a synergistic relationship with both water retention services and soil retention services, with synergy areas accounting for 54.91% and 44.46% of the total area, respectively. …”
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Robust and Adaptive Tuning of PI Current Controllers for Grid-Forming Inverters by Florian Reisner, George Weiss

“…While very efficient in strong grids, such control architectures face stability problems if the grid short-circuit ratio becomes low. …”
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A Randomized Placebo-Controlled N-of-1 Trial: The Effect of Proton Pump Inhibitor in the Management of Gastroesophageal Reflux Disease by Fernando Sierra-Arango, D. M. Castaño, Jennifer D. Forero, Erika D. Pérez-Riveros, Gerardo Ardila Duarte, Maria L. Botero, Andres Cárdenas, Jose De la Hoz-Valle

“…N-of-1 trials in chronic pathologies including GERD are recommended due to their potential value as systematic methods that evaluate therapies without strong scientific evidence.…”
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Association of objective and subjective socioeconomic markers with cognitive impairment among older adults: cross-sectional evidence from a developing country by Shobhit Srivastava, T Muhammad, TV Sekher

“…Interaction analyses revealed that older adults who belonged to lower subjective and objective (poorest MPCE quintile, Scheduled Castes and lowest education) SES had 2.45 (CI: 1.77 to 3.39), 4.56 (CI: 2.97 to 6.98) and 54.41 (CI: 7.61 to 388.93) higher odds of cognitive impairment than those from higher subjective and objective SES, respectively.Conclusion Subjective measures of SES were linked to cognitive outcomes, even more strongly than objective measures of SES; considering the relative ease of obtaining such measures, subjective SES measures are a promising target for future study on socioeconomic indicators of cognitive impairment.…”
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Repeatability, reproducibility, and the effects of radiotherapy on radiomic features of lowfield MR-LINAC images of the prostate by Parker Anderson, Nesrin Dogan, John Chetley Ford, Kyle Padgett, Garrett Simpson, Radka Stoyanova, Matthew Charles Abramowitz, Alan Dal Pra, Rodrigo Delgadillo

“…Reproducibility of RFs between different modalities was not strong. This study demonstrated that we can reliably use onboard MRI to observe day-to-day feature changes as a result of RT.…”
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Multimorbidity in Atherosclerotic Cardiovascular Disease and Its Associations With Adverse Cardiovascular Events and Healthcare Costs: A Real-World Evidence Study by Dingwei Dai, Joaquim Fernandes, Xiaowu Sun, Laura Lupton, Vaughn W. Payne, Alexandra Berk

“…Multimorbidity patterns varied considerably across ASCVD patients and by age, gender, and social vulnerability status. Multimorbidity was strongly associated with ACEs and healthcare costs.…”
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Factors associated with attention-deficit/hyperactivity disorder among Tunisian children by Asma Guedria, Asma Guedria, Asma Guedria, Mohamed Guedria, Manel Ben Fredj, Manel Ben Fredj, Randaline Ayoub, Randaline Ayoub, Randaline Ayoub, Hela Ben Abid, Hela Ben Abid, Hela Ben Abid, Ahmed Mhalla, Ahmed Mhalla, Ahmed Mhalla, Hela Slama, Hela Slama

“…In the early childhood period, early exposure to television was also strongly associated with ADHD. However, the multivariate model conducted to determine the variables independently associated with ADD/ADHD revealed only three determining factors: passive smoking during pregnancy (OR = 4.60 [2.14, 9.94]; p &lt; 0.001), acute fetal distress (OR = 5.08 [1.47, 17.52]; p = 0.01), and familial psychiatric history (OR = 9.37 [2.46, 35.59]; p = 0.001).DiscussionThe recognition of factors involved in the genesis of ADHD within different ethnic populations may help understanding and broaden our knowledge of this disorder to develop targeted strategies for prevention and early intervention. …”
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Biofilm-Producing Bacteria and Risk Factors (Gender and Duration of Catheterization) Characterized as Catheter-Associated Biofilm Formation by Wani Devita Gunardi, Anis Karuniawati, Rainy Umbas, Saptawati Bardosono, Aida Lydia, Amin Soebandrio, Dodi Safari

“…Biofilm-producing bacteria, female gender, duration of catheterization (more than five days), and PapC gene presence have strong correlation with the biofilm formation. To prevent CAUTI, patients with risk factors should be monitored by urinalysis tests to detect earlier the risk of biofilm formation.…”
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Exploring the General Acceptability and User Experience of a Digital Therapeutic for Cognitive Training in a Singaporean Older Adult Population: Qualitative Study by Siong Peng Kwek, Qiao Ying Leong, V Vien Lee, Ni Yin Lau, Smrithi Vijayakumar, Wei Ying Ng, Bina Rai, Marlena Natalia Raczkowska, Christopher L Asplund, Alexandria Remus, Dean Ho

“…Participants also showed a strong awareness of the importance of cognitive training and expressed a keen interest in using CURATE.DTx for this purpose, especially if recommended by medical professionals. …”
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Research and insights for application of CO2-ECBM technology in deep high-rank coal seams: a case study of Jinzhong block, Qinshui Basin by Yongwang ZHENG, Yinan CUI, Xin LI, Cui XIAO, Tao GUO, Dengfeng ZHANG

“…Deep high-rank coal seams have significant resource potential, but exhibit characteristics of "strong adsorption and weak desorption", making it challenging to effectively utilize with conventional development methods. …”
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Assessing the validity and reliability of the Indonesian version of Patient-Reported Outcomes Measurement Information System (PROMIS) Global Health Scale v1.2 by Vitriana Biben, Farida Arisanti, Efi Fitriana, Erika Maklun, Vindy Margaretha Miguna, Nabilla Fikria Alviani

“…Result The Indonesian version of PROMIS Global Health Scale v1.2 showed strong validity and reliability. Content validity analysis produced a S-CVI/Universal Agreement of 0.90 with item analysis factor loading’s of > 0.3. …”
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Identification of Ferroptosis-Associated Long Noncoding RNA Prognostic Model and Tumor Immune Microenvironment in Thyroid Cancer by Yongjian Lin, Fu Gan, Xiaoyu He, Huachu Deng, Yong Li

“…Meanwhile, we found a strong association between Ferr-LPM and TIME. Interestingly, the LPM_score was inversely proportional to the tumor purity but positively related to immune checkpoint blockade (ICB) response. …”
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Phylogeographic breaks and how to find them: An empirical attempt at separating vicariance from isolation by distance in a lizard with restricted dispersal by Rancilhac, Loïs, Miralles, Aurélien, Geniez, Philippe, Mendez-Aranda, Daniel, Beddek, Menad, Brito, José Carlos, Leblois, Raphaël, Crochet, Pierre-André

“…Results: A. erythrurus is characterized by an important mitochondrial diversity, with 11 strongly supported phylogeographic lineages with a crown age of 6 Mya. …”
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Antimicrobial Activity of the Synthesized of Copper Chalcogenide Nanoparticles by N. G. Mbewana-Ntshanka, M. J. Moloto, P. K. Mubiayi

“…The sensitivity of copper oxide nanoparticles is attributed to the smaller size of oxygen atom which strongly affects its reactivity and stability and hence very stable and highly reactive compared to sulfur and selenium.…”
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Comprehensive analysis of antimicrobial resistance dynamics among broiler and duck intensive production systems by Zsombor Szoke, Peter Fauszt, Maja Mikolas, Peter David, Emese Szilagyi-Tolnai, Georgina Pesti-Asboth, Judit Rita Homoki, Ildiko Kovacs-Forgacs, Ferenc Gal, Laszlo Stundl, Levente Czegledi, Aniko Stagel, Sandor Biro, Judit Remenyik, Melinda Paholcsek

“…In farm environments 15 broiler-specific and 9 duck-specific biomarker species were identified, each strongly correlated with poultry-core HRCs (correlation coefficient > 0.7). …”
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Comparison of the extraction efficiencies of four different solvents used in trace metal digestion of selected soils within Abakaliki, Nigeria by NO Omaka, IF Offor, ER Chukwu, U Ewuzie

“…Results revealed that all extractants showed strong positive correlation in bringing only Cd into solution. …”
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Evaluation of Inflammatory Markers and Clinical Outcomes in COVID-19 Patients with Concurrent <i>Clostridioides difficile</i> Infection: A Comparative Cohort Analysis by Flavia Ignuta, Adrian Vlad, Teodor Cerbulescu, Stana Loredana, Felix Bratosin, Ovidiu Rosca, Lavinia Stelea, Daciana Nistor

“…Inflammatory indices correlated strongly with disease severity: elevated CAR and low PNI were associated with higher odds of ICU admission and mortality (<i>p</i> < 0.001). …”
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Influence of fruit stages on chemical compositions, phytochemicals, and antioxidant activity of wood apple (Feronia limonia (L.) Swingle) by Rashmi Srivastava, Neha Mishra, Arshi, Shraddha Tripathi, Smriti, Neha Taslim Fatima, Neetu Mishra

“…Individually, phenol and flavonoid compounds shown a strong Pearson's association with the antioxidant activity of the fruit, including DPPH scavenging activity (0.945, 0.915), ferric reducing antioxidant power (FRAP) (0.980, 0.907), metal chelating activity (MCA) (0.953, 0.914), and reducing capacity (RC) (0.981, 0.906). …”
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Neuroprotective role of epigallocatechin-3-gallate, albeginin and melanoxetin in alzheimer's disease by Arif Malik, Mehreen Hassan, Sulayman Waquar, Muhammad Wasim, Anam Naz, Faryal M. Awan, Muhammad T. Khan, Ali I. Khawaja, Sumera Zaib, Jamshed Iqbal, Ayesha Zahid, Marvi Marvi, Javeid Iqbal, Heng Wang, Dong-Qing Wei

“…Results: In silico results indicated strong binding interactions of EGCG, albeginin, and melanoxetin with the target proteins. …”
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