Development and validation of a nomogram for predicting lung cancer based on acoustic–clinical features by Zhou Lu, Zhou Lu, Jiaojiao Sha, Xunxia Zhu, Xiaoyong Shen, Xiaoyu Chen, Xin Tan, Rouyan Pan, Shuyi Zhang, Shi Liu, Tao Jiang, Jiatuo Xu

“…Furthermore, the nomogram model was compared with predictive models that were developed using six additional machine-learning (ML) methods.ResultsOur acoustic–clinical nomogram model demonstrated a strong discriminative ability, with AUCs of 0.774 (95% confidence interval [CI], 0.716–0.832) and 0.714 (95% CI: 0.616–0.811) in the training and test sets, respectively. …”
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Ecological risk assessment of future suitable areas for Piper kadsura under the background of climate change by Shimeng Li, Yuanxin Li, Mingli Hu, Mingli Hu, Yankun Li, Yankun Li, Mingrong Yang, Shi Wang, Shi Wang, Wei Yu, Wei Yu, Chunsong Cheng, Qiqing Cheng, Qiqing Cheng

“…The market demand of P. kadsura is huge, but its wild resources are scarce and artificial cultivation methods have not been established, which leads to a situation with strong contradiction and imbalance between supply and demand.MethodsIn this study, 303 sample of distribution data for P. kadsura in China were collected, 33 environmental variables related to terrain, climate and soil were analyzed and the suitable habitats of P. kadsura during various periods were predicted by MaxEnt model and ArcGIS software, aiming to provide a basis for scientific cultivation and effective utilization of resources.ResultsThe results indicated that precipitation and temperature were significant factors in the distribution of P. kadsura. …”
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Transformation and fate of Fe(III) in petroleum-hydrocarbon-contaminated soil and groundwater by Essouassi Elikem, David Bulmer, Kris Bradshaw, Ardalan Hayatifar, Matthew B. J. Lindsay, Steven D. Siciliano, Derek Peak

“…The presence of major Fe(II) phases in the subsoils strongly indicate that secondary Fe(III) phases (especially Fe(III)-OM complex/coprecipitate) served as terminal electron acceptors during the microbial degradation of PHCs in the contaminated subsurface.…”
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Evolution within a given virulence phenotype (pathotype) is driven by changes in aggressiveness: a case study of French wheat leaf rust populations by Fontyn, Cécilia, Meyer, Kevin JG, Boixel, Anne-Lise, Delestre, Ghislain, Piaget, Emma, Picard, Corentin, Suffert, Frédéric, Marcel, Thierry C, Goyeau, Henriette

“…In some cases, these strong selection pressures cannot fully explain the evolution observed in pathogen populations. …”
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Effects of varying doses of caffeine intake on physiological responses among university hockey players in Edo State, Nigeria by Agharese Efe-Aigbovo, Vincent Imagbovomwan

“…Hockey players in the three experimental groups made up of 16 players (8 males and 8 females) each were subjected to the ingestion of three (3) separate doses of 260mg, 520mg, and 780mg respectively of strong black unsweetened coffee in cups, one hour before testing. …”
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Psychometric Testing of the CHAMPS Questionnaire in French Canadians with COPD by Susanne Mak, Jean Bourbeau, Nancy E. Mayo, Sharon Wood-Dauphinee, Judith E. Soicher

“…CHAMPS frequency scores for moderate-intensity activities correlated more strongly than other scores, with physical aspects of the SF-36 and SGRQ. …”
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Cross-cultural adaptation and psychometric evaluation of the Thai version of the Enhancing Recovery in Coronary Heart Disease Social Support Inventory in individuals with chronic i... by Santi Phetrnui, Jom Suwanno, Chantira Chiaranai, Chonchanok Bunsuk, Naruebeth Koson, Wanna Kumanjan, Chennet Phonphet, Ladda Thiamwong

“…Conclusions: Our study affirms the strong validity and reliability of the ESSI in the Thai population with chronic illnesses. …”
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High prevalence of p16 staining in malignant tumors. by Noémi De Wispelaere, Sebastian Dwertmann Rico, Marcus Bauer, Andreas M Luebke, Martina Kluth, Franziska Büscheck, Claudia Hube-Magg, Doris Höflmayer, Natalia Gorbokon, Sören Weidemann, Katharina Möller, Christoph Fraune, Christian Bernreuther, Ronald Simon, Christian Kähler, Anne Menz, Andrea Hinsch, Frank Jacobsen, Patrick Lebok, Till Clauditz, Guido Sauter, Ria Uhlig, Waldemar Wilczak, Stefan Steurer, Eike Burandt, Rainer Krech, David Dum, Till Krech, Andreas Marx, Sarah Minner

“…It is concluded, that a positive and especially strong p16 immunostaining is a feature for malignancy which may be diagnostically useful in lipomatous, urothelial and possibly other tumors. …”
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Application of Solenoid Valves for Tram Hydraulic Braking Force Control by ZHANG Yanwei, MAO Jinglu, WANG Cong, WANG Zhongxiang, HAO Xinxin

“…Compared with proportional pressure reducing valve, the high-speed switching valve features strong pollution resistance, which can lower the failure rate of the braking system. …”
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BRD4 Inhibitor GNE-987 Exerts Anticancer Effects by Targeting Super-Enhancer-Related Gene LYL1 in Acute Myeloid Leukemia by Xu Sang, Yongping Zhang, Fang Fang, Li Gao, Yanfang Tao, Xiaolu Li, Zimu Zhang, Jianwei Wang, Yuanyuan Tian, Zhiheng Li, Di Yao, Yumeng Wu, Xinran Chu, Kunlong Zhang, Li Ma, Lihui Lu, Yanling Chen, Juanjuan Yu, Ran Zhuo, Shuiyan Wu, Zhen Zhang, Jian Pan, Shaoyan Hu

“…Conclusions. GNE-987 had strong antitumor activity in AML. GNE-987 could effectively inhibit the expression of SE-related oncogenes including LYL1 in AML. …”
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Characterization of Somatostatin Receptor Subtype 2 Expression in Stably Transfected A-427 Human Cancer Cells by Jesse J. Parry, Martin Eiblmaier, Rebecca Andrews, Laura A. Meyer, Ryuji Higashikubo, Carolyn J. Anderson, Buck E. Rogers

“…These studies showed that there was a strong correlation among the in vitro assays and between the in vitro assays and the biodistribution. …”
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Drop-size-dependent effects in leading-edge rain erosion and their impact on erosion-safe mode operation by N. Barfknecht, D. von Terzi

“…The outcome is that drop-size effects strongly impact the erosion process and should not be neglected during modeling. …”
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EFFECTS OF MODERATELY VIRULENT AFRICAN SWINE FEVER VIRUS ON INTERLEUKIN-10 PRODUCTION by A. S. Pershin, I. V. Shevchenko, A. S. Igolkin, Ye. V. Aronova, N. N. Vlasova

“…The aim of this paper was to study the effect of African swine fever virus on the production of IL-10, a pleiotropic cytokine that inhibits synthesis of cytokines and shows a strong antiinflammatory effect. For this, 12 piglets were experimentally infected intramuscularly with a continuous cell culture-adapted ASFV isolate Vero25 at a dose of 10 HAdU per animal followed by control infection of surviving animals with the reference virus isolate Arm 07 at a dose of 1,000 HAdU per animal. …”
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Digital measurement of ocular microtremor in Parkinson's disease: Protocol for a pilot study to assess reliability and clinical validation. by Lisa Graham, Rodrigo Vitorio, Richard Walker, Alan Godfrey, Rosie Morris, Samuel Stuart

“…The link between OMT and brain function provides a strong rationale for investigation as there lies potential for its use as a biomarker in populations with neurological impairments. …”
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Pharmacological Preconditioning Improves the Viability and Proangiogenic Paracrine Function of Hydrogel-Encapsulated Mesenchymal Stromal Cells by Francesco K. Touani, Melanie Borie, Feryel Azzi, Dominique Trudel, Nicolas Noiseux, Shant Der Sarkissian, Sophie Lerouge

“…In vivo, the proangiogenic activity was studied by evaluating the neovessel density around the subcutaneously injected hydrogel after one week in rats. Preconditioning strongly enhanced the viability of rMSC and hMSC compared to vehicle-treated cells, with 90% and 75% survival versus 36% and 58% survival, respectively, after 7 days in complete media and 80% versus 64% survival for hMSC after 4 days in low serum media (p<0.05). …”
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Understanding the implementation strategy of a secondary care tobacco addiction treatment pathway (the CURE project) in England: a strategic behavioural analysis by Matthew Evison, Anna Haste, Catherine Haighton, Freya Howle, Angela M Rodrigues, Angela Wearn, Verity Mallion

“…Recommendations to optimise content were developed following stakeholder engagement.Conclusions CURE offers a strong foundation from which a tobacco dependence treatment model can be developed in England. …”
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Preparation, Purification, Identification and Anti-lipid Oxidation of Kidney Bean Skin Polyphenols by Lilan SUN, Kun WANG, Youliang ZHANG, Ruokun WANG, Feng ZUO

“…In conclusion, kidney bean skin polyphenols had strong antioxidant properties and potential as a safe natural food antioxidant.…”
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A compact and highly isolated integrated 8-port MIMO antenna for sub-6 GHz and mm-wave 5G-NR applications by Manumula Srinubabu, Nuthakki Venkata Rajasekhar

“…The antenna demonstrates excellent isolation and gain, with S21 values below -25 dB and peak gains of 11.75 dBi and 12 dBi for the sub-6 GHz and mm-wave bands, respectively. It also exhibits strong diversity performance, with an envelope correlation coefficient8x8 of 0.004 and efficiencies ranging from 88% to 96% for the respective frequency bands. …”
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Evaluation of the Effect of Different Glazing Brands on Surface Roughness of Monolithic Zirconia by Riyam Imad Fouad, Lateef Essa Alwan Al Jorani, Abdel Kareem Jasim Khadim Al-Azzawi

“… The effect of glazing on the mechanical properties of monolithic high translucent zirconia is widely used to fabricate highly aesthetic and strong dental restorations using CAD-CAM technology. …”
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Lysosome-related proteins may have changes in the urinary exosomes of patients with acute gout attack by Jitu Wang, Na Liu, Mei Hu, Man Zhang

“…The ROC analysis showed that CTSZ, AP1B1 and LAMP2 had a strong ability to predict acute gout attack, with AUC of 0.826, 0.847 and 0.882, respectively. …”
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