Novel insights into immunopathogenesis and crucial biomarkers between primary open‐angle glaucoma and systemic lupus erythematosus by Yixian Liu, Mengling You, Zhou Zeng, Jing Wang, Rong Rong, Xiaobo Xia

“…Furthermore, the DSigDB database yielded 10 potential therapeutic agents, three of which showed strong binding potential to the biomarkers via molecular docking. …”
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Rapid Screening and Estimation of Binding Constants for Interactions of Fe3+ with Two Metalloproteins, Apotransferrin and Transferrin, Using Affinity Mode of Capillary Electrophore... by Mohammed Al Bratty, Hassan A. Alhazmi, Sadique A. Javed, Zia Ur Rehman, Asim Najmi, Karam A. El-Sharkawy

“…However, transferrin exhibited significant interactions with the metal ion at 50 and 100 μmol/mL (ΔR/Rf = 0.0114 and 0.0201, resp.) concentrations and apotransferrin showed strong binding interactions (ΔR/Rf = −0.0254 and 0.0205, resp.) at relatively higher Fe3+ concentrations of 100 and 250 μmol/mL. …”
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Limitations to Dynamical Error Suppression and Gate-Error Virtualization from Temporally Correlated Nonclassical Noise by Michiel Burgelman, Nattaphong Wonglakhon, Diego N. Bernal-García, Gerardo A. Paz-Silva, Lorenza Viola

“…We study a minimal exactly solvable single-qubit model under Gaussian quantum dephasing noise, showing that the fidelity of a dynamically protected idling gate can depend strongly on its location in the circuit and the history of applied control, even when the system-side error propagation is fully removed through perfect reset operations. …”
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Molecular Characterization of the Tumor Suppressor Candidate 5 Gene: Regulation by PPARγ and Identification of TUSC5 Coding Variants in Lean and Obese Humans by Trina A. Knotts, Hyun Woo Lee, Jae Bum Kim, Pieter J. Oort, Ruth McPherson, Robert Dent, Keisuke Tachibana, Takefumi Doi, Songtao Yu, Janardan K. Reddy, Kenji Uno, Hideki Katagiri, Magdalena Pasarica, Steven R. Smith, Dorothy D. Sears, Michel Grino, Sean H. Adams

“…Tumor suppressor candidate 5 (TUSC5) is a gene expressed abundantly in white adipose tissue (WAT), brown adipose tissue (BAT), and peripheral afferent neurons. Strong adipocyte expression and increased expression following peroxisome proliferator activated receptor γ (PPARγ) agonist treatment of 3T3-L1 adipocytes suggested a role for Tusc5 in fat cell proliferation and/or metabolism. …”
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Reservoir Physical Properties and Micropore Nanocharacteristics of Cores in the Shihezi Formation, Sudong District, Sulige Gas Field, Ordos Basin by Xin Zhang, Feng Wang, Shuyi Liang, Qintao Guo, Jingchun Tian, Bingyue Shen

“…Sulige gas field is a very complex large-scale gas field with low porosity, low permeability, low abundance, and strong heterogeneity. In this study, the nanopore structure of the reservoir in the study area was analyzed. …”
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Study of legume-rhizobia symbiosis in soybean for agroecosystem resilience by Oleksandr Mazur, Olena Mazur, Tetiana Tymoshchuk, Ihor Didur, Viacheslav Tsyhanskyi

“…Varieties Ametyst, Artemida, and Hoverla showed a particularly strong response to inoculation with nitrogenfixing bacteria and are recommended for cultivation in diverse environmental conditions. …”
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Assessing the Roles of Molecular Markers of Antimalarial Drug Resistance and the Host Pharmacogenetics in Drug-Resistant Malaria by Peter Hodoameda, Nancy Odurowah Duah-Quashie, Neils Ben Quashie

“…Since both host and parasite genomes play a role in antimalarial drug action, a key question often asked is, “which of the two strongly drives or controls antimalarial drug resistance?” …”
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Leveraging mRNA technology for antigen based immuno-oncology therapies by Wei Zheng, Michele Ceccarelli, Charalampos S Floudas, Siranush Sarkizova

“…We explore various strategies for antigen target identification, including tumor-associated and tumor-specific antigens and the computational tools used to predict epitopes capable of eliciting strong immune responses. We address key design considerations for enhancing the immunogenicity and stability of mRNA vaccines, as well as emerging trends and challenges in the field. …”
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Advanced TiO2-polypyrrole nanostructures enhance glucose detection accuracy with cutting-edge non-enzymatic electrochemical capabilities by Ashima Thakur, Sweety Pal, Usha Sharma, Ajit Sharma, Meenakshi Choudhary, Mukesh C. Joshi, Herma Dina Setiabudi, Prabal Pratap Singh, Atheesha Singh, Sudheesh K. Shukla

“…Additionally, TiO2-PPy the sensor confirmed the excellent stability and reproducibility, along with strong potential for practical application in real sample analysis. …”
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Combined application of FTAN and cross-spectra analysis to ambient noise recorded by a microseismic monitoring network by Ilaria Barone, Alessandro Brovelli, Giorgio Tango, Sergio Del Gaudio, Giorgio Cassiani

“…Errors as large as 4% have been found, related to the unfavorable orientation of the receiver pairs with respect to strongly directional noise sources, and to the very short time widows. …”
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Insights into the Regional Transport and Local Formation of Secondary Organic Aerosol in Delhi, India by Himadri Sekhar Bhowmik, Sachchida Nand Tripathi, Ravi Sahu, Ashutosh Kumar Shukla, Vipul Lalchandani, Shamitaksha Talukdar, Nidhi Tripathi, Lokesh Sahu

“…Higher OC/EC ratios during these episodes could be due to a strong primary source, and this possibility cannot be ruled out. …”
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Genomic data suggest parallel dental vestigialization within the xenarthran radiation by Emerling, Christopher A, Gibb, Gillian C, Tilak, Marie-Ka, Hughes, Jonathan J, Kuch, Melanie, Duggan, Ana T, Poinar, Hendrik N, Nachman, Michael W, Delsuc, Frédéric

“…Here we report evidence of independent and distinct events of dental gene loss in the major xenarthran subclades. First, we found strong evidence of complete enamel loss in the common ancestor of sloths and anteaters, suggested by the inactivation of five enamel-associated genes (AMELX, AMTN, MMP20, ENAM, ACP4). …”
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MRD-driven phase 2 study of daratumumab, carfilzomib, lenalidomide, and dexamethasone in newly diagnosed multiple myeloma by Manisha Bhutani, Myra Robinson, David Foureau, Shebli Atrash, Barry Paul, Fei Guo, Jason M. Grayson, Anna Ivanina-Foureau, Mauricio Pineda-Roman, Cindy Varga, Reed Friend, Christopher J. Ferreri, Xhevahire Begic, Sarah Norek, Tiffany Drennan, Michelle B. Anderson, James T. Symanowski, Peter M. Voorhees, Saad Z. Usmani

“…We observed that Dara-KRd strongly activated memory T cells, which was associated with an MRD-negative state post induction. …”
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PaleAle 6.0: Prediction of Protein Relative Solvent Accessibility by Leveraging Pre-Trained Language Models (PLMs) by Wafa Alanazi, Di Meng, Gianluca Pollastri

“…When evaluated on the more challenging 2024 test set, PaleAle 6.0 maintained a strong performance, achieving 79.74% accuracy in the two-state prediction and 55.30% accuracy in the four-state prediction, with a PCC of 73.08 for real-value predictions, outperforming all previously benchmarked predictors.…”
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Robust Identification of Vegetation Change Using Shapelet-Based Temporal Segmentation of Landsat Time-Series Stacks: A Case Study in the Qilian Mountains by Lipeng Jiao, Randolph H. Wynne

“…These results highlight SVCD's strong potential for precise, noise-resistant vegetation change detection.…”
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Quantifying uncertainty in anthropogenic causes of injury and mortality for an endangered baleen whale by Daniel W. Linden, Jeffrey A. Hostetler, Richard M. Pace III, Lance P. Garrison, Amy R. Knowlton, Véronique Lesage, Rob Williams, Michael C. Runge

“…We examined variation in the hazard rates of severe injury and mortality due to entanglements in fishing gear and vessel strikes as explained by temporal patterns and the age and reproductive status of the individual. We found strong evidence for increased rates of severe entanglement injuries after 2013 and for females with calves, with consequently higher marginal mortality. …”
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Donkey milk supplementation alleviates renal fibrosis of chronic kidney disease by enhancing anti-inflammatory ability by Cui Huimin, Wang Peng, Chen Man, Lin Hong, Zhao Yuxin, Pu Zhiyu, Yang Jianjun

“…ABSTRACT: Donkey milk, rich in essential nutrients, is not only able to meet the nutritional needs of patients with chronic kidney disease (CKD) according to the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative Clinical Practice Guideline for Nutrition in CKD, but also has strong anti-inflammatory properties. Inflammation is the main driving force of renal fibrosis, which directly determines renal function in CKD. …”
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Evaluation of Total Electron Content Prediction Using Three Ionosphere‐Thermosphere Models by O. Verkhoglyadova, X. Meng, A. J. Mannucci, J.‐S. Shim, R. McGranaghan

“…Prediction success is between about 0.2 and 0.5 for weak ionospheric disturbances and decreases for strong disturbances. We evaluate the prediction of TEC decreases and increases. …”
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Between Consecutive Fractures: Time and Sex as Dominant Factors in Type and Severity Concordance of Contralateral Hip Injuries by Neta Leshem, Ido Stahl, Farouk Khury, Ianiv Trior Simonovich

“…<b>Results</b>: The study included 182 fractures in 91 patients (68% women, mean age: 79.5 and 82.2 years at first and second fractures, respectively; mean TI: 975 days). A strong association (lambda = 0.437, <i>p</i> < 0.001) was demonstrated between the first and second fracture classifications, which was higher in men (lambda = 0.60, <i>p</i> < 0.001) and for TI < 3 years (lambda = 0.625–0.688, <i>p</i> < 0.001). …”
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Evaluation of Silkworm Lines against Variations in Temperature and RH for Various Parameters of Commercial Cocoon Production by Mubashar Hussain, Shakil Ahmad Khan, Muhammad Naeem, Tahir Aqil, Rizwan Khursheed, Ata ul Mohsin

“…The study clearly underlines the importance of optimization of environmental conditions during larval rearing in relation to commercial cocoon production. The investigations strongly recommend that temperature and relative humidity in the range of 25-26 °C and 70–80%, respectively, are mandatory for excellent results of cocoon production and Pak-4, M-101, Pak-2, Pak-3, PFI-I, and M-107 were suitable for commercial rearing.…”
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