Dysregulation of Metabolic Peptides Precedes Hyperinsulinemia and Inflammation Following Exposure to Rotenone in Rats by Vandana Zaman, Denise Matzelle, Naren L. Banik, Azizul Haque

“…Administration of rotenone to rats also increased body weight and activated macrophages and inflammatory T cells. These data strongly suggest that rotenone disrupts metabolic homeostasis, leading to obesity and hyperinsulinemia. …”
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An Experimental Study on the Adsorption and Desorption of Cu(II) in Silty Clay by Shuang Xie, Zhang Wen, Hongbin Zhan, Menggui Jin

“…The adsorption capacity of Cu(II) is less than the desorption capacity under the condition of strong acidity and low concentration of Cu(II). In addition, the adsorption capacity of the native soil on Cu(II) was larger than that of the soil with the removal of organic matter, while the opposite was true for the desorption capacity on Cu(II). …”
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Association between HLA-B Alleles and Carbamazepine-Induced Maculopapular Exanthema and Severe Cutaneous Reactions in Thai Patients by Chonlaphat Sukasem, Chonlawat Chaichan, Thapanat Nakkrut, Patompong Satapornpong, Kanoot Jaruthamsophon, Thawinee Jantararoungtong, Napatrupron Koomdee, Suthida Sririttha, Sadeep Medhasi, Sarawut Oo-Puthinan, Ticha Rerkpattanapipat, Jettanong Klaewsongkram, Pawinee Rerknimitr, Papapit Tuchinda, Leena Chularojanamontri, Napatra Tovanabutra, Apichaya Puangpetch, Wichai Aekplakorn

“…The HLA-B∗15:02 allele has been reported to have a strong association with carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) in Thai patients. …”
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Synapsis and recombination of autosomes and sex chromosomes in two terns (Sternidae, Charadriiformes, Aves) by A. P. Lisachov, L. P. Malinovskaya, A. V. Druzyaka, P. M. Borodin, A. A. Torgasheva

“…The mammals show high karyological variability, which strongly influences the recombination patterns. Therefore it is important to study recombination rate and distribution in more karyologically stable taxa, such as reptiles and birds. …”
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Association between the prognosis and comorbidity of active cancer in chronic thromboembolic pulmonary hypertension by Hiroyuki Fujii, Yu Taniguchi, Yuichi Tamura, Miki Sakamoto, Sachiyo Yoneda, Kenichi Yanaka, Noriaki Emoto, Ken-ichi Hirata, Hiromasa Otake

“…However, patients with CTEPH frequently have comorbid cancer, which may be a strong prognostic factor.…”
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Evaluation of Yellow Fever Virus Infection in <i>Aedes aegypti</i> Mosquitoes from Pakistan with Distinct Knockdown Resistance Genotypes by Carlucio Rocha dos Santos, Caleb Guedes Miranda dos Santos, Dinair Couto-Lima, Bárbara Silva Souza, Rafi Ur Rahman, Marcos Dornelas Ribeiro, José Bento Pereira Lima, Ademir Jesus Martins

“…Mosquito populations have undergone strong selective pressure owing to the excessive use of insecticides. …”
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Efficacy of Voriconazole Corneal Intrastromal Injection for the Treatment of Fungal Keratitis by Chenshuang Li, Kunpeng Pang, Liqun Du, Xinyi Wu

“…To evaluate efficacy and safety of novel tricyclic corneal stroma injection (TCSI) voriconazole for the treatment of fungal keratitis. …”
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The nonlinear association between body roundness index and infertility in married women by Yong Fang, Danfeng Ren, Jinliang Pan, Qiuyuan Xu

“…This study is the first to rigorously affirm a strong link between increased BRI and the higher prevalence of infertility among married women aged 20–45. …”
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Mobile Integrated Healthcare: Preliminary Experience and Impact Analysis with a Medicare Advantage Population by Daniel J. Castillo, J. Brent Myers, Jonathan Mocko, Eric H. Beck

“…These preliminary findings indicate both that implementation of such a program is feasible and strongly suggest meritorious impacts upon the health, experience and cost of care for the population.…”
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Glucose Metabolic Brain Network Differences between Chinese Patients with Lewy Body Dementia and Healthy Control by Danyan Chen, Jiaying Lu, Hucheng Zhou, Jiehui Jiang, Ping Wu, Qihao Guo, Jingjie Ge, Huiwei Zhang, Kuangyu Shi, Chuantao Zuo

“…Amongst them, in the DLB group, betweenness centrality became strong in OLF.R, HIP.R, and FFG.L, whereas betweenness centrality became weaker in IFG.R. …”
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Studies on humoral immunity in dogs after use of rabies inactivated vaccines formulated with Montanide ISA 70 VG and GEL 01 adjuvants by A. N. Balashov, M. I. Doronin, A. V. Borisov, D. A. Lozovoy, D. V. Mikhalishin, V. A. Starikov

“…The presented rabies vaccines formulated with oil adjuvant Montanide ISA 70 VG and gel adjuvant Montanide GEL 01 were innocuous and safe and induced strong immunity in all vaccinated animals. The vaccine formulated with Montanide ISA 70 VG adjuvant in case of a single administration in the dose of 1.0 cm3 induces formation of rabies virus-neutralizing antibodies in the level of 2.4 times higher than the vaccine formulated with Montanide GEL 01 adjuvant. …”
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Sample Size and Statistical Power Calculation in Genetic Association Studies by Eun Pyo Hong, Ji Wan Park

“…We found that a much lower sample size was required with a strong effect size, common SNP, and increased LD. …”
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Corpus software in EFL teaching: Examination of language exposure by A. V. Kudryashova, Ya. V. Rozanova, T. V. Sidorenko

“…The vocabulary does not completely reflect the realities of the business communication sphere and the distribution of active vocational vocabulary regulated by methodological guidelines does not entirely contribute to its strong assimilation. According to the authors, the necessary changes to the approaches and methods for selecting and compiling lexical material and to the methodology for designing a foreign language course should be made on the basis of integrating pedagogical and linguistic knowledge, in particular, the methodology of teaching foreign languages and the corpus linguistics.Practical significance. …”
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A Real-Time Vision Transformers-Based System for Enhanced Driver Drowsiness Detection and Vehicle Safety by Anwar Jarndal, Hissam Tawfik, Ali I. Siam, Imad Alsyouf, Ali Cheaitou

“…Testing the prototype yielded highly promising results, with the system&#x2019;s strong performance attributed to the ViT-DDD system and advanced hardware. …”
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S6P mutation in Delta and Omicron variant spike protein significantly enhances the efficacy of mRNA COVID-19 vaccines by Yong-Sik Bong, David Brown, Ezra Chung, Neeti Ananthaswamy, Renxiang Chen, Renxiang Chen, Evan Lewoczko, William Sabbers, Athéna C. Patterson-Orazem, Zachary Dorsey, Yiqing Zou, Xue Yu, Jiening Liang, Jiaxi He, Steven Long, Dong Shen

“…Both RV-1730 and RV-1731 provided superior protection in preclinical models, indicating enhanced efficacy due to the S6P mutation.ConclusionThe incorporation of the S6P mutation into the Delta variant spike protein significantly enhances the immunogenicity and efficacy of mRNA-based COVID-19 vaccines. The strong performance of RV-1730 as a heterologous booster and the broad-spectrum activity of the bivalent RV-1731 vaccine underscore their potential as versatile and effective vaccination strategies against SARS-CoV-2 and its evolving variants.…”
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Isolation, characterization and liposome-loaded encapsulation of a novel virulent Salmonella phage vB-SeS-01 by Yuhang Luo, Jacques Mahillon, Lin Sun, Ziqiong You, Xiaomin Hu

“…Furthermore, nine phage-carrying liposome formulations were developed by film hydration method and via liposome extruder.Results and DiscussionPhage vB-SeS-01 displays strong lysis ability against 9 out of 24 tested S. enterica strains (including the pathogenic “Sendai” and “Enteritidis” serovars), high replicability with a burst size of 111 ± 15 PFU/ cell and a titre up to 2.1 × 1011 PFU/mL, and broad pH (4.0 ~ 13.0) and temperature (4 ~ 80°C) stabilities. …”
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Contributions of Biomass Burning and Other Sources to Fine Particle Level and Oxidative Potential in Suburban Tokyo, Japan by Akihiro Fushimi, Ana M. Villalobos, Akinori Takami, Kiyoshi Tanabe, James J. Schauer

“…Neither open burning nor vehicle exhaust source contributions showed a strong positive correlation with the PM2.5 oxidative potential.…”
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Human soft tissue sarcomas harbor an intratumoral viral microbiome which is linked with natural killer cell infiltrate and prognosis by William J Murphy, Robert J Canter, Nikhil Joshi, Sean J Judge, Morgan A Darrow, Steve W Thorpe, Alicia A Gingrich, Lauren M Perry, Sylvia M Cruz, Kara T Kleber, Louis B Jones, Ugur N Basmaci, Matthew L Settles, Blythe P Durbin-Johnson, Arta Monir Monjazeb, Janai Carr-Ascher, Jonathan A Eisen

“…We sought to characterize the intratumoral microbiome in patients with STS undergoing preoperative radiotherapy and surgery, hypothesizing the presence of a distinct intratumoral microbiome with potentially clinically significant microbial signatures.Methods We prospectively obtained tumor and stool samples from adult patients with non-metastatic STS using a strict sterile collection protocol to minimize contamination. …”
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Lithological and geochemical characterization of ‘adinole’ artefacts from cave deposits in southwest Wales: A material of choice during the late Middle to Upper Palaeolithic by Richard Bevins, Elizabeth A. Walker, Nick Pearce, Duncan Pirrie, Rob Ixer, Ian Saunders, Matthew Power

“…Identifying rhyolite rather than adinole as the raw material used in the manufacture of the studied artefacts negates the need to consider long distance transport of either raw materials or finished artefacts. It strongly suggests that people in southwest Wales, where raw materials were scarce, were using materials that were local to them. …”
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Determinants of hypertension-related knowledge, attitude, and practices (KAP) among caregivers in Neno, rural Malawi: A cross-sectional study by Chikondi Maluwa, Sitalire Kapira, Hataichanok Chuljerm, Wason Parklak, Kanokwan Kulprachakarn

“…However, no significant relationship was observed between attitude and practice (r = +0.064; p = 0.190). Age showed a strong correlation with attitude (r = +0.233; p < 0.001) but not with knowledge or practice. …”
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