Risk factors associated with poor pain outcomes following primary knee replacement surgery: Analysis of data from the clinical practice research datalink, hospital episode statistics and patient reported outcomes as part of the STAR research programme. by Hasan Raza Mohammad, Rachael Gooberman-Hill, Antonella Delmestri, John Broomfield, Rita Patel, Joerg Huber, Cesar Garriga, Christopher Eccleston, Rafael Pinedo-Villanueva, Tamer T Malak, Nigel Arden, Andrew Price, Vikki Wylde, Tim J Peters, Ashley W Blom, Andrew Judge

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Striking a Chord with Spectral Sirens: Multiple Features in the Compact Binary Population Correlate with H0 by Utkarsh Mali, Reed Essick

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Culture Change and Quality of Care Among High Medicaid Nursing Homes: Does Earlier Implementation Matter? by Latarsha Chisholm, Akbar Ghias, Rohit Pradhan, Justin Lord, Ganisher Davlyatov, Robert Weech-Madonado

“… Context: High Medicaid nursing homes are under-resourced and associated with lower resident quality of care. Culture change initiatives, a movement to transition nursing homes to more home-like environments, are a potential process to improve residents’ quality of life and care. …”
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Questionnaire survey on the clinical application of Hall technique preformed metal crowns in caries of primary molars in China by Junhui Wang, Baize Zhang, Yujiang Chen, Lulu Wang, Yang Du, Xin Ge, Fen Liu, Fen Liu, Jing Gong, Jing Gong, Xiaojing Wang

“…ObjectiveTo analyze the clinical application and limiting factors of the Hall technique (HT) preformed metal crowns in caries of primary molars and to provide reference for its clinical application based on a questionnaire survey.Materials and methodsFrom June to December 2022, a questionnaire was distributed to pediatric dentists through the WeChat platform using “Questionnaire Star” to analyze the clinical application and influencing factors of the HT preformed metal crowns in caries of primary molars.ResultsA total of 700 survey questionnaires were distributed, and 650 valid questionnaires were recovered, with a effectiveness rate of 92.86%. …”
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Impact of Moderate Sedation versus Monitored Anesthesia Care on Outcomes and Cost of Endobronchial Ultrasound Transbronchial Needle Aspiration by Ziad Boujaoude, Rohan Arya, Aseem Shrivastava, Melvin Pratter, Wissam Abouzgheib

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Engaging older adults in diagnostic safety: implementing a diagnostic communication note sheet in a primary care setting by Alberta Tran, Leah Blackall, Mary A. Hill, Mary A. Hill, William Gallagher

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Survey on the Status and Training Demands of Capabilities for Diagnosing and Treating Common Diseases of Primary Care General Practitioners in Hunan Province by LI Lingqi, GAO Yinyan, ZHANG Yuqin, SUN Dingkui, WU Xinyin, ZHANG Weiru

“…Additionally, 77.2% (260/337) of participants lacked sufficient knowledge of clinical practice guidelines; 90.8% (306/337) of participants rarely consulted guidelines when facing decision-making difficulties, mainly because they felt guidelines could not address complex cases[50.0% (153/306) ], were unclear on how to search for guidelines[43.1% (132/306) ]and the resources available for retrieving guidelines[34.3% (105 /306) ]; participants mainly obtain the guidelines through the WeChat official account[72.5% (237/327) ] and databases such as the China National Knowledge Infrastructure [50.2% (164/327) ]. 97.0% (327/337) of participants expressed a demand for training to improve their capabilities, suggesting that training should be tailored to the specific needs of primary care institutions[60.8% (205/337) ]; the preferred approaches are advanced training in higher-level hospitals[71.3% (233/327) ]and primary care institutions with high diagnostic and treatment capabilities[56.3% (184/327) ]; the preferred training programs are on standardized treatment of common diseases[78.0% (263/337) ]and multiple coexisting diseases[69.4% (234/337) ]. …”
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Can Variation in Costs for Cardiovascular Procedures Be Attributed to Inefficiency in Care Delivery? Challenges in Causality, Data Availability, and the Need for Price Transparency by Waseem Nosair, MD, MPH, Morgana Mongraw-Chaffin, PhD, MPH, William S. Weintraub, MD

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Comorbidities And Reducing InEquitieS (CARES): Feasibility of self-monitoring and community health worker support in management of comorbidities among Black breast and prostate can... by Laura C. Schubel, Ana Barac, Michelle Magee, Mihriye Mete, Malinda Peeples, Mansur Shomali, Kristen E. Miller, Lauren R. Bangerter, Allan Fong, Christopher Gallagher, Jeanne Mandelblatt, Hannah Arem

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Healthcare utilization and related costs among older people seeking primary care due to back pain: findings from the BACE-N cohort study by Danielle van der Windt, Milada Cvancarova Småstuen, Kjersti Storheim, Margreth Grotle, Zinajda Zolic-Karlsson, Ørjan Nesse Vigdal, Rikke Munk Killingmo, Lise Kretz

“…Objectives To describe healthcare utilization and estimate associated costs during 1 year of follow-up among older people seeking primary care due to a new episode back pain and to describe healthcare utilization across patients with different risk profiles stratified using the StarT Back Screening Tool (SBST).Design Prospective cohort study.Participants and setting A total of 452 people aged ≥55 years seeking Norwegian primary care with a new episode of back pain were included.Outcome measures The primary outcome of this study was total cost of healthcare utilization aggregated for 1 year of follow-up. …”
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Investigating the miRNA-mRNA interactome of human trabecular meshwork cells treated with TGF-β1 provides insights into the pathogenesis of pseudoexfoliation glaucoma. by Anton W Roodnat, Chelsey Doyle, Breedge Callaghan, Karen Lester, Megan Henry, Carl Sheridan, Declan J McKenna, Colin E Willoughby, Sarah D Atkinson

“…For both mRNA and miRNA species, differential expression was determined using a bioinformatics pipeline consisting of FastQC, STAR, FeatureCounts, edgeR (for miRNA) and DESeq2 (for mRNA). …”
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Protocol for assessing and visualizing cell microaggregate formation in whole blood by imaging flow cytometry by Johannes Krell, Komal Kumar Javarappa, Angie Wenedy, Andrew L. Frelinger, III, Laurent Renia, Clarissa Prazeres da Costa, Martin Schlegel, Percy Knolle, Gerhard Schneider, Oliver Hayden

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Protocol for a patient-derived preclinical platform to model tumor-immune interactions and evaluate therapeutic efficacy by Wen-Hsin Chang, Andrew I. Chin, Ching-Hsien Chen

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Protocol for quantifying muscle fiber size, number, and central nucleation of mouse skeletal muscle cross-sections using Myotally software by Pieter Both, Soochi Kim, Jengmin Kang, Marina Arjona, Daniel I. Benjamin, Christopher W. Nutter, Armon Goshayeshi, Thomas A. Rando

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Protocol for investigating astrocytic mitochondria in neurons of adult mice using two-photon microscopy by Jian Zhou, Fengling Du, Fan Zhang, Xianhui Zhang, Yuanyuan Wu, Lifang Zhang, Ping Liao, Tianqi Tu, Jianhua Peng, Tao Li, Yong Jiang

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Protocol for generating and characterizing a nasal epithelial model using imaging with application for respiratory viruses by Victor H.K. Lam, Aleena Ghafoor, Yazan Khan, Shirley Constable, Lane B. Buchanan, David Zuanazzi, Reeya Parmar, Zeynep G. Tepe, Leigh J Sowerby, Cindy M. Liu, Ryan M. Troyer, Jessica L. Prodger

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Is It the pH That Matters? Challenging the Pathophysiology of Acidemia in a Case of Severe Hypercapnia Secondary to Intraoperative CO2 Insufflation by Evan Merle, Saad Zaatari, Rory Spiegel

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Plaque Rupture-Induced Myocardial Infarction and Mechanical Circulatory Support in Alpha-Gal Allergy by Sohab S. Radwan, Gauravpal Gill, Amre Ghazzal, Awais Malik, Christopher Barnett

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Suspected Sugammadex Hypersensitivity following Repeated Administration in the Setting of Multiple Flap Takebacks in a Brief Timespan by Elizabeth G. Zolper, Alan H. Kim, Kevin G. Kim, Paige K. Dekker, Jenna C. Bekeny, David H. Song, Kenneth L. Fan

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