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4921
Pathogenetic therapeutic approaches for endocrine diseases based on antisense oligonucleotides and RNA-interference
Published 2025-01-01“…In the context of endocrine disorders, molecular therapy is particularly effective in modulating pathogenic mechanisms such as defective insulin signaling, beta-cell dysfunction and hormonal imbalances. Furthermore, siRNA and ASOs have the ability to downregulate overactive signaling pathways that contribute to complex, non-monogenic endocrine disorders, thereby addressing these conditions at their molecular origin. …”
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4922
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4923
Vegetative Propagation of Perennial Cut Flower Flax (Linum spp.) in a Controlled Environment
Published 2025-02-01“…We tested mist house (MH) rooting time (2 or 3 weeks) and rooting hormone concentrations [1000 or 2000 ppm indole-3-butyric acid (IBA)]. …”
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4924
The Clinical Effect of Oral Vitamin D2 Supplementation on Psoriasis: A Double-Blind, Randomized, Placebo-Controlled Study
Published 2019-01-01“…Serum levels of 25(OH)D, calcium, phosphate, parathyroid hormone, and C-reactive protein and adverse events were monitored. …”
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4925
A Dermatological Intervention of Gynecomastia in Young Asian Man with a History of Soy Product Consumption: A Case Report
Published 2025-01-01“…Gynecomastia is common in infants, adolescents, and elderly men, with the most common cause is related to hormonal changes associated with aging. Medical intervention is usually required for true gynecomastia that has lasted more than a year. …”
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4926
Extrinsic attributes that drive consumer purchase of block mozzarella
Published 2025-02-01“…Consumers found “produced without added hormones,” “made with milk from our pasture-raised cows,” and “made locally” to be the most appealing label claims. …”
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4927
Assessment of Zinc Alpha-2 Glycoprotein Level in Gestational Diabetes Woman in Respect to Glycemic Status with and without Treatment
Published 2025-01-01“…It is distinguished by substantial insulin resistance induced by the secretion of placental hormone. Adipocytes secrete a particular type of adipocytokine called zinc a2 glycoprotein (ZAG), and numerous reasearches have suggested that ZAG is involved in crucial physiological processes such as glucose metabolism. …”
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4928
Evaluation of IL-29 in Euthyroid Patients with Graves’ Orbitopathy: A Preliminary Study
Published 2020-01-01“…The following parameters were evaluated in every participant: thyroid-related hormones and autoantibodies and inflammatory markers (white blood cells, hsCRP). …”
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4929
Early Sialadenitis After Radioactive Iodine Therapy for Differentiated Thyroid Cancer: Prevalence and Predictors
Published 2020-01-01“…Pretreatment thyroid stimulating hormone (TSH) was greater than 75 mIU/ml in most patients (72.6%). …”
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4930
Factors affecting DH plants <i>in vitro</i> production from microspores of European radish
Published 2020-03-01“…At regeneration and tiller stage it is advisable to add 1 mg/mL of benzylaminopurine and 0.1 mg/L of gibberellic acid to the medium, and rotting of micro-sprouts is performed with the use of hormone-free medium. Analysis of the produced regenerant plants by chromosome count and cell nucleus flow cytometry showed that 69 % of plants have a diploid chromosome set, 9 % have a haploid chromosome set, and 22 % have mixoploids and aneu-ploids chromosome sets. …”
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4931
A sustainable breakthrough in rodent pest control: laboratory validation of novel neem-andrographolide bait with dual toxic and contraceptive effects
Published 2025-02-01“…Remaining live rats revealed significant reduction in the body weight, weight of reproductive organs, duration of estrous cycle, number of both normal and atretic follicles, and level of sex hormones in all the treated groups. Mating behaviour and reproductive success were also affected in all the treated groups. …”
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4932
Adequately Iodized Salt Utilization and Associated Factors among Households in Tach Armachio District, Northwest Ethiopia: A Community-Based Cross-Sectional Study
Published 2021-01-01“…For the synthesis of thyroid hormones, iodine is a crucial trace element. Iodine deficiency disorders affect all groups particularly: pregnant, young women and children. …”
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4933
Age effects on measurements of hypothalamic-pituitary-adrenal axis activation in laying hens
Published 2025-03-01“…However, hypothalamic-pituitary-adrenal axis (HPA) activation through either exogenous glucocorticoid or adrenocorticotropic hormone (ACTH) administration in birds generally results in increased circulating glucocorticoid levels, often associated with stress. …”
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4934
The Influence of Concurrent Autoimmune Thyroiditis on the Cardiometabolic Consequences of Cabergoline in Postmenopausal Women
Published 2025-01-01“…In addition to prolactin, we assessed thyroid-stimulating hormone (TSH), thyroid antibodies, and glucose homeostasis markers: fasting glucose, the homeostatic model assessment 1 of insulin resistance ratio (HOMA1-IR), and glycated hemoglobin (HbA1c). …”
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4935
Serum Indicators Reflecting Gastric Function May Also Correlate with Other Extragastric Diseases
Published 2015-01-01“…As thyroid peroxidase antibody (TPOAb) levels increased, PGI level decreased from 100.85 to 84 µg/L (P<0.05) and as thyroid stimulating hormone (TSH) increased, PGI/II ratio increased monotonically from 11.54 to 12.68 (P<0.05). …”
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4936
Real-World Treatment Patterns in Men with Castration- Resistant Prostate Cancer Receiving Docetaxel
Published 2015-01-01“…Other non-chemotherapy treatments used with docetaxel were hormonal therapy (22.8%), radiotherapy (17.3%), and surgery (4.1%). …”
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4937
Cost-effectiveness Analysis of Ribociclib plus Letrozole versus Palbociclib plus Letrozole in the United Kingdom
Published 2019-04-01“…**Objective:** To evaluate the cost-effectiveness of ribociclib plus letrozole versus palbociclib plus letrozole in post-menopausal women with hormone receptor positive (HR+) and human epidermal growth receptor 2 negative (HER2-) advanced breast cancer from a UK payer perspective. …”
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4938
Impact of Seasonal Variations on Semen Parameters: A Retrospective Analysis of Data from Subjects Attending a Tertiary Care Fertility Centre
Published 2023-04-01“…The data of azoospermic and severe oligospermic (<5 million/mL) men and those receiving hormone treatment were excluded. Statistical Analysis Used: Data were analysed using SPSS 23 and variables expressed as mean and standard deviation. …”
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4939
Effects of Immediate or Delayed Estradiol on Behavior in Old Menopausal Macaques on Obesogenic Diet
Published 2018-01-01“…This study approached several questions: (1) does a western-style diet (WSD) contribute to sedentary behavior or is sedentary behavior a consequence of obesity and (2) does estradiol (E) hormone therapy offset WSD or ameliorate sedentary behavior? …”
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4940
Sarco(endo)plasmic Reticulum Ca2+-ATPase-2 Gene: Structure and Transcriptional Regulation of the Human Gene
Published 2002-01-01“…It contains a TATA-like-box, an E-box/USF sequence, a CAAT-box, four Sp1 binding sites, and a thyroid hormone responsive element (TRE). There are two other conserved regulatory regions located between positions -410 to -661 bp and from -919 to -1410 bp. …”
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