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4901
Bioinformatics analysis combined with experimental validation reveals the biological role of the ILK gene in prostate cancer
Published 2025-01-01“…The integrin-linked kinase (ILK) gene has been identified as an oncogenic driver in hormonal cancers, including PCa. Methods To identify key genes in PCa, we utilized differential gene expression analysis and Weighted Gene Co-expression Network Analysis (WGCNA). …”
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4902
Cross-sectional association between plasma aldosterone concentration and cognitive performance by mini-mental state examination in community dwellers
Published 2025-02-01“…BackgroundAldosterone is the effector hormone in the renin angiotensin aldosterone system and existing data suggest aldosterone affect cognitive function. …”
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4903
Inverse Relationship Between Leydig Cell Density and Metastatic Potential of Prostatic Adenocarcinoma
Published 1999-01-01“…Conclusions: Patients with metastatic adenocarcinoma of prostate, as a group, have a significantly lower Leydig cell density than patients without metastasis or patients without PC in compatible age groups. The hormonal relationship between this observation is however unknown. …”
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4904
The Role of Prolactin as a Disease Activity Indicator in Some Rheumatic Diseases
Published 2025-07-01“…Background: Autoimmune rheumatic diseases, including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and scleroderma, predominantly affect women and are characterized by systemic inflammation, leading to organ failure. Prolactin (PRL), a hormone produced by the pituitary gland and lymphocytes, significantly affects immune regulation and is implicated in the pathophysiology of these diseases. …”
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4905
Identifying MTHFD1 and LGALS4 as Potential Therapeutic Targets in Prostate Cancer Through Multi-Omics Mendelian Randomization Analysis
Published 2025-01-01“…The treatment of it is currently based on surgical removal, radiotherapy, and hormone therapy. It is crucial to improve therapeutic prospects for the diagnosis and treatment of prostate cancer via drug target screening. …”
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4906
A Nonfunctioning Pituitary Macroadenoma Presenting as Cyclical Vomiting and Severe Hyponatremia in a Young Female
Published 2021-01-01“…Nonfunctioning pituitary macroadenomas generally present with visual disturbances, headache, and symptoms due to anterior pituitary hormone deficiencies. This case report is about an atypical presentation of a nonfunctioning pituitary macroadenoma in which the patient presented with cyclical vomiting with severe hyponatremia. …”
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4907
Combined extracts of Syzygium aromaticum (Clove) and Xylopia aethiopica (Negro pepper) seeds inhibit testosterone propionate-induced benign prostatic hyperplasia in Wistar rats
Published 2024-12-01“…Conclusion: The mechanisms of BPH inhibition involve the regulation of sex hormone levels and the amelioration of conditions caused by oxidative damage. …”
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4908
Immune checkpoint inhibitors-related thyroid dysfunction: influencing factor analysis, prediction model development, and management strategy proposal
Published 2024-11-01“…Results The systematic review encompassed 21 observational studies involving 4,145 patients, revealing associations between ICI-TD and factors such as female gender, age, receipt of Pembrolizumab (versus other ICIs), and baseline levels of thyroid-stimulating hormone, free thyroxine, and antithyroid antibodies. …”
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4909
Transcriptomic Profile Analysis of Brain Tissue in the Absence of Functional TRPM8 Calcium Channel
Published 2024-12-01“…Specifically, we focused on brain regions integral to behavioral and hormonal control, including the olfactory bulb, hypothalamus, amygdala, and insula. …”
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4910
Urine metabolic profile in rats with arterial hypertension of different genesis
Published 2024-05-01“…To identify metabolomic markers for hypertensive conditions of different origins, three forms of arterial hypertension (AH) were studied: rats with hereditary AH (ISIAH rat strain); rats with AH induced by L-NAME administration (a model of endothelial dysfunction with impaired NO production); rats with AH caused by the administration of deoxycorticosterone in combination with salt loading (hormone-dependent form – DOCAsalt AH). …”
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4911
Cosmetic Appeal, HRQoL, and Effectiveness of Simple and Pseudotesticular Techniques of Orchidectomy in Prostate Cancer
Published 2021-01-01“…Orchidectomy is the most cost-effective means of hormonal therapy for locally advanced or metastatic prostate cancer (LAMP). …”
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4912
Genetic basis of depressive disorders
Published 2019-07-01“…In addition, there is evidence of the involvement of HPA-axis genes (OXTR, AVPR1A, and AVPR1B), sex hormone receptors genes (ESR1, ESR2, and AR), neurotrophin (BDNF) and methylenetetrahydrofolate reductase (MTHFR) genes, neuronal apoptosis (CASP3, BCL-XL, BAX, NPY, APP, and GRIN1) and inflammatory system (TNF, CRP, IL6, IL1B, PSMB4, PSMD9, and STAT3) genes in DD development. …”
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4913
Risk Factors Associated with Breast Cancer in Women in a Health Area
Published 2023-11-01“…Breast cancer was considered as the dependent variable; the following were used as independent variables: age, personal and family pathological history, early menarche, late menopause, nulliparity, age of the first child, exclusive breastfeeding, replacement or replacement hormone therapy, use of contraceptive methods, obesity, sedentary lifestyle, smoking, alcoholism. …”
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4914
Lighting quality evaluation on growth performance and feather pecking behavior of broilers
Published 2025-01-01“…To evaluate the quality of lighting in production of a local broiler breed, this study was designed to investigate the effects of light color on the growth performance (body weight, feed conversion ratio and upper beak length), welfare parameters (walking step, plumage damage and hormone level) relating to feather pecking and their correlations. …”
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4915
Characteristics Associated with Acute-Phase Response following First Zoledronic Acid Infusion in Brazilian Population with Osteoporosis
Published 2021-01-01“…Clinical demographics (age, sex, diabetes, smoking, body mass index, and previous oral bisphosphonate use) and laboratory data (calcium, parathyroid hormone, renal function, and serum 25-hydroxyvitamin D and carboxy-terminal crosslinked telopeptide of type 1 collagen [CTX], both before and after infusion) were compared between patients with and without APR. …”
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4916
Total Parathyroidectomy with Subcutaneous Parathyroid Forearm Autotransplantation in the Treatment of Secondary Hyperparathyroidism: A Single-Center Experience
Published 2018-01-01“…Parathyroidectomy is indicated in refractory hyperparathyroidism when medical treatments and so the parathyroid hormone levels cannot be lowered to acceptable values without causing significant hyperphosphatemia or hypercalcemia. …”
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4917
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4918
"Cuéntame tus testosteronas": Un análisis sobre las regulaciones para jugadorxs transgénero e hiperandrógenas
Published 2020-01-01“…Si antes el foco estaba enquistado en la genitalidad, en la actualidad se centra en el control hormonal, en ambas situaciones bajo la aplicación de tecnologías de control del cuerpo cuyo fin es disciplinarlo.Con todo, consideramos que poder revisar qué sucede en nuestros contextos locales con las demandas de los colectivos disidentes nos permite repensar nuestras instituciones y aportar una mirada crítica en la deconstrucción y reconstrucción de deportes para todxs.…”
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4919
RETRACTED: The role of biofield energy treatment on psychological symptoms, mental health disorders, and stress‐related quality of life in adult subjects: A randomized controlled c...
Published 2023-05-01“…Furthermore, physiological biomarkers: vitamins (B12, C, and D3 metabolites), immune biomarker (CD8+CD28−), neurotransmitters (acetylcholine, noradrenaline, and dopamine), hormones (oxytocin, 17‐β‐estradiol, and insulin), and antiaging protein (klotho) levels were significantly (p ≤ 0.001) increased in treatment group than placebo. …”
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4920
Genome-wide identification and expression analysis of ZF-HD family in sunflower (Helianthus annuus L.) under drought and salt stresses
Published 2025-02-01“…The analysis of cis-acting element demonstrated that the response elements related the hormone response and abiotic/biotic stress were the most prevalent, followed by plant growth and development elements. …”
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