Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway by Laura La Paglia, Angela Listì, Stefano Caruso, Valeria Amodeo, Francesco Passiglia, Viviana Bazan, Daniele Fanale

“…The transcriptional regulation of ANGPTL4 can be modulated by several transcription factors, including PPARα, PPARβ/δ, PPARγ, and HIF-1α, and nutritional and hormonal conditions. Several studies showed that high levels of ANGPTL4 are associated with poor prognosis in patients with various solid tumors, suggesting an important role in cancer onset and progression, metastasis, and anoikis resistance. …”
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Type 1 Diabetes Mellitus in Saudi Arabia: A Soaring Epidemic by Asirvatham Alwin Robert, Abdulrahman Al-Dawish, Muhammad Mujammami, Mohamed Abdulaziz Al Dawish

“…More alarmingly, the incidence of T1DM among infants is also increasing, with children as young as 6 months succumbing to it, instead of that at a rather established vulnerable age of around seven and near puberty, when the hormones antagonize the action of insulin. These reports pose a unique challenge of developing efficient T1DM management system for the young children. …”
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SOCS2 inhibits the tumorigenesis of GISTs and increases the sensitivity of GISTs to imatinib by suppression of KIT activation by Liangying Zhang, Kun Xiao, Shaoting Zhang, Sien Zhao, Zimei Liu, Ming Wang, Kaiyue Qin, Yuanyuan Yu, Shujing Li, Lijun Ma, Jianmin Sun

“…Abstract The suppressors of cytokine signaling 2 (SOCS2) inhibits growth hormone receptor (GHR) signaling by negative feedback in the regulation of metabolism. …”
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Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases by Ajit A. Kulkarni, Collynn F. Woeller, Thomas H. Thatcher, Sesquile Ramon, Richard P. Phipps, Patricia J. Sime

“…Peroxisome proliferator activated receptor (PPAR)-γ is a nuclear hormone receptor that is activated by multiple agonists including thiazolidinediones, prostaglandins, and synthetic oleanolic acids. …”
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Calcific Uremic Arteriolopathy: A Case Series and Review from an Inner-City Tertiary University Center in End-Stage Renal Disease Patients on Renal Replacement Therapy by Mohamed Omer, Zeenat Yousuf Bhat, Nanette Fonte, Nashat Imran, James Sondheimer, Yahya Osman‐Malik

“…Diabetes mellitus was the most prevalent cause of ESRD. The parathyroid hormone level (PTH) was elevated in 22 patients. Fifteen patients were diagnosed 2 weeks or more prior to skin lesion onset. …”
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International Burden of Chronic Kidney Disease and Secondary Hyperparathyroidism: A Systematic Review of the Literature and Available Data by Elizabeth Hedgeman, Loren Lipworth, Kimberly Lowe, Rajiv Saran, Thy Do, Jon Fryzek

“…Among the few nations reporting, approximately 30–50% of stage 5D patients had serum parathyroid hormone levels >300 pg/mL. Reported incidence and prevalence estimates across the individual nations were variable, likely reflecting differing population demographics, risk factors, etiologies, and availability of treatment through all stages of CKD.…”
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Urinary Concentrations of Steroids in Bulls under Anabolic Treatment by Revalor-XS® Implant by Giancarlo Biancotto, Roberto Stella, Federica Barrucci, Francesca Lega, Roberto Angeletti

“…The aim of the research was to measure the residual urinary concentrations of the administered drugs (β-trenbolone and β-estradiol), their main metabolites (α-trenbolone and α-estradiol), and possible alterations of the urinary profile of other endogenous hormones metabolically related. The analytical method was based on liquid chromatography-tandem mass spectrometry. …”
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Long-Term Follow-Up of Patients with 46,XY Partial Gonadal Dysgenesis Reared as Males by Juliana Gabriel Ribeiro de Andrade, Antonia Paula Marques-de-Faria, Helena Campos Fabbri, Maricilda Palandi de Mello, Gil Guerra-Júnior, Andréa Trevas Maciel-Guerra

“…Studies on 46,XY partial gonadal dysgenesis (PGD) have focused on molecular, gonadal, genital, and hormone features; little is known about follow-up. …”
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A scoping review on heat indices used to measure the effects of heat on maternal and perinatal health by Anayda Portela, Debra Jackson, Nathalie Roos, Chuansi Gao, Francesca Conway, Ijeoma Solarin, Chloe Brimicombe, Darshnika Lakhoo

“…Negative birth outcomes can occur from change in hormonal levels (ie, cortisol), dehydration and blood flow diversion away from the placenta and fetus when suffering from heat stress. …”
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A gene expression atlas of Nicotiana tabacum across various tissues at transcript resolution by Shizhou Yu, Jufen Wan, Jufen Wan, Tenghang Xu, Tenghang Xu, Jie Zhang, Linggai Cao, Jie Liu, Hongfeng Liu, Xueliang Ren, Zhixiao Yang

“…Furthermore, sQTLs involved genes related to plant hormone signal transduction, terpenoid backbone biosynthesis, and other resistance pathways. …”
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Detection and Analysis of Autoantigens Targeted by Autoantibodies in Immunorelated Pancytopenia by Hui Liu, Rong Fu, Yihao Wang, Hong Liu, Lijuan Li, Honglei Wang, Jin Chen, Hong Yu, Zonghong Shao

“…Most patients responded well to adrenocortical hormone and/or high-dose intravenous immunoglobulin treatment, indicating that cytopenia might be mediated by autoantibodies. …”
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An Unusual Case of Resistant Hypokalaemia in a Patient with Large Bowel Obstruction Secondary to Neuroendocrine Carcinoma of the Prostate by Umasankar Mathuram Thiyagarajan, A. Ponnuswamy, A. Bagul, A. Gupta

“…A 70-year-old man presented with clinical signs of large bowel obstruction who was known to have prostatic carcinoma three years ago, treated initially with hormone therapy then chemoradiation. The blood profile showed a severe hypokalaemia and CT scan revealed liver and lung metastases apart from confirming large bowel obstruction from local invasion of NECP. …”
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Dexamethasone potentiates the insulin-induced Srebp-1c expression in primary rat hepatocytes by Yan Zhang, Xiangming Fang, Fen Shuang, Guoxun Chen

“…The impacts of dexamethasone (Dex) and thyroid hormone T3 on the insulin-stimulated Srebp-1c expression were studied in primary rat hepatocytes. …”
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Immune-endocrine crossroads: the impact of nuclear receptors in Tuberculosis and Chagas disease by Ana R. Pérez, Ana R. Pérez, Oscar A. Bottasso, Oscar A. Bottasso, Oscar A. Bottasso, Natalia E. Santucci, Natalia E. Santucci

“…Over time, disturbances in cytokine, hormone, and other compound production foster an unbalanced, detrimental defensive response. …”
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Etiopathogenesis of Sheehan’s Syndrome: Roles of Coagulation Factors and TNF-Alpha by Halit Diri, Elif Funda Sener, Fahri Bayram, Nazife Tascioglu, Yasin Simsek, Munis Dundar

“…Sheehan’s Syndrome (SS) is defined as pituitary hormone deficiency due to ischemic infarction of the pituitary gland as a result of massive postpartum uterine hemorrhage. …”
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Inflammatory Pain and Corticosterone Response in Infant Rats: Effect of 5-HT1A Agonist Buspirone Prior to Gestational Stress by Irina P. Butkevich, Viktor A. Mikhailenko, Tat'yana R. Bagaeva, Elena A. Vershinina, Anna Maria Aloisi, Vladimir A. Otellin

“…Chronic treatments of rat dams with buspirone before restraint stress during gestation normalize in the offspring pain-like behavior and induce during the acute phase in the formalin test the stronger corticosterone increase as compared to the stress hormonal elevation in animals with other prenatal treatments. …”
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Cisplatin-Induced Renal Salt Wasting Requiring over 12 Liters of 3% Saline Replacement by Phuong-Chi Pham, Pavani Reddy, Shaker Qaqish, Ashvin Kamath, Johana Rodriguez, David Bolos, Martina Zalom, Phuong-Thu Pham

“…A diagnosis of syndrome of inappropriate antidiuretic hormone secretion (SIADH) was initially made. Despite free water restriction, patient’s SNa continued to decrease in association with acute onset of headaches, nausea, and dizziness. …”
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Mechanism of microplastics in the reduction of cadmium toxicity in tomato by Rongchao Yang, Long Cheng, Zhenqin Li, Yilan Cui, Jiawei Liu, Duo Xu, Sijia Liu, Zhong Lin, Jiugeng Chen, Yueqin Zhang

“…Transcriptome analysis further revealed that combined treatment reprogrammed key pathways, including cell wall synthesis, antioxidant systems, Cd transport, hormone signaling, nitrogen metabolism, and glutathione metabolism, to alleviate Cd toxicity. …”
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Pointing out persuasion in Philemon by P.B. Decock

“…This encyclopedia surveys not only sermons and commentaries, but also the various ways in which biblical texts have been received, such as in the creative arts, including paintings, sculptures, novels, films and music. …”
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Scrotal Skin Metastases Revealing a Prostatic Adenocarcinoma by Idriss Ziani, Zayd El Boukili El Makhoukh, Ahmed Ibrahimi, Omar Bellouki, Jihane Benahmed, Yasmine Laraqui, Fouad Zouidia, Hachem El Sayegh, Lounis Benslimane, Yassine Nouini

“…The patient received second-generation hormone therapy with good clinical and biological outcomes. …”
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