Acromegaly: Role of Surgery in the Therapeutic Armamentarium by Gerardo Guinto, Miguel Abdo, Erick Zepeda, Norma Aréchiga, Moisés Mercado

“…Somatostatin analogues are included as the first line of medication, followed by dopamine agonist and growth hormone receptors antagonists. Radiation therapy can be also indicated in two main forms for residual tumor with medically refractory patients: radiosurgery for small tumors or fractionated stereotactic radiotherapy for larger ones.…”
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SMARCA4-Deficient Carcinoma of Unknown Primary Presenting with Fatal Paraneoplastic Hypercalcemia in a Heart Transplant Recipient: First Report in a Male Patient by Abbas Agaimy, Deike Strobel, Thomas Strecker

“…The serum parathyroid hormone-related protein (PTHrp) was significantly elevated (241 pg/ml; reference value < 57). …”
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Lead toxicity in Nicotiana tabacum L.: Damage antioxidant system and disturb plant metabolism by Tengfei Liu, Kai Zhang, Chunlan Ming, Jiashu Tian, Huanyu Teng, Zicheng Xu, Jiewang He, Fengfeng Liu, Yinghui Zhou, Jiayang Xu, Mohamed G. Moussa, Shenghua Zhang, Wei Jia

“…These results indicate that increasing the content of photosynthetic pigments and hormones, clearing reactive oxygen species by enhancing antioxidant enzyme activity, and improving amino acid metabolism may play an important role in reducing the toxicity of Pb to tobacco.…”
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Nonfunctioning Pituitary Adenoma That Changed to a Functional Gonadotropinoma by Gerson Geovany Andino-Ríos, Lesly Portocarrero-Ortiz, Carlos Rojas-Guerrero, Alejandro Terrones-Lozano, Alma Ortiz-Plata, Alfredo Adolfo Reza-Albarrán

“…We report the case of a woman who initially had a nonfunctional gonadotropinoma and in the course of her medical condition showed biochemical changes in her hormonal pituitary profile compatible with a functional gonadotropinoma. …”
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Fortified Iodine Milk Improves Iodine Status and Cognitive Abilities in Schoolchildren Aged 7–9 Years Living in a Rural Mountainous Area of Morocco by Fatima Ezzahra Zahrou, Mehdi Azlaf, Imane El Menchawy, Mohamed El Mzibri, Khalid El Kari, Asmaa El Hamdouchi, Fatima-Zahra Mouzouni, Amina Barkat, Hassan Aguenaou

“…Iodine is required for the production of the thyroid hormones essential for the growth and development of the brain. …”
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Histopathological Characterization and Whole Exome Sequencing of Ectopic Thyroid: Fetal Architecture in a Functional Ectopic Gland from Adult Patient by Rosalinda Yasato Camargo, Cristina Takami Kanamura, Celso Ubirajara Friguglietti, Célia Regina Nogueira, Sonia Iorcansky, Alfio José Tincani, Ana Karina Bezerra, Ester Brust, Fernanda Christtanini Koyama, Anamaria Aranha Camargo, Fernanda Orpinelli R. Rego, Pedro Alexandre Favoretto Galante, Geraldo Medeiros-Neto, Ileana Gabriela Sanchez Rubio

“…This is the first immature thyroid fetal tissue observed in an ectopic thyroid due to the arrest of structural differentiation early in the colloid stage of development that proved able to synthesize thyroid hormone but not to respond to TSH. Despite the ability of all ectopic thyroids to synthetize specific thyroid proteins and T4, at some point in life, it may be insufficient to support body growth leading to hypothyroidism, as observed in some of the patients.…”
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What Am I? Descartes’s Various Ways of Considering the Self by Colin Chamberlain

“…For example, the self is simple considered as a mind, whereas the self is composite considered as a human being. Someone might object that it is unclear how merely considering the self in different ways blocks the conclusion that a single subject of predication—the self—is both simple and composite, which is contradictory. …”
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Predicting the Rise of EU Right-Wing Populism in Response to Unbalanced Immigration by Boris Podobnik, Marko Jusup, Dejan Kovac, H. E. Stanley

“…The latter is likely due to the perception that the EU functions as a supranational state in which a lack of inner borders means that “someone else’s problem” can easily become “my problem.” …”
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The Social Burden of Witchcraft accusation and Its Victims: An Exercise in Philosophy by Olusegun Stephen Taiwo

“…For in a witch-case the suspect was usually a person who had been involved in a relationship of real or presumed hostility towards the victim, then an accusation of witchcraft originated with someone living in close proximity to the suspect, and was meant to explain some local and personal misfortune. …”
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Innovative Diagnostic Approaches and Treatment Strategies for Endometriosis: Current Trends and Future Direction - Review by Wiktoria Domino, Joanna Śnieżna, Wojciech Florczak, Karol Dzwonnik, Urszula Zelik, Jagienka Włodyka, Gabriela Trestka, Maria Przygoda, Jakub Dziewic, Kamila Stępień, Sabina Adamczyk

“…Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to alleviate symptoms, while hormonal therapies, such as combined oral contraceptives, GnRH agonists, and progestogens, aim to inhibit ovulation and estrogen production to reduce inflammation and slow disease progression. …”
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Beta-Thalassemia Major and Female Fertility: The Role of Iron and Iron-Induced Oxidative Stress by Paraskevi Roussou, Nikolaos J. Tsagarakis, Dimitrios Kountouras, Sarantis Livadas, Evanthia Diamanti-Kandarakis

“…Infertility in these women seems to be attributed to iron deposition and iron-induced oxidative stress (OS) in various endocrine organs, such as hypothalamus, pituitary, and female reproductive system, but also through the iron effect on other organs, such as liver and pancreas, contributing to the impaired metabolism of hormones and serum antioxidants. Nevertheless, the gonadal function of these patients is usually intact and fertility is usually retrievable. …”
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Carrizo citrange Plants Do Not Require the Presence of Roots to Modulate the Response to Osmotic Stress by Rosa M. Pérez-Clemente, Almudena Montoliu, Sara I. Zandalinas, Carlos de Ollas, Aurelio Gómez-Cadenas

“…Different parameters such as plant performance, organ length, antioxidant activities, and endogenous contents of proline, malondialdehyde, and hormones were determined. Differently to that observed under high salinity, when subjected to osmotic stress conditions, Carrizo citrange showed increased endogenous levels of MDA, proline, and ABA. …”
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Tramadol Induced Adrenal Insufficiency: Histological, Immunohistochemical, Ultrastructural, and Biochemical Genetic Experimental Study by Shereen Abdelhakim Abdelaleem, Osama A. Hassan, Rasha F. Ahmed, Nagwa M. Zenhom, Rehab A. Rifaai, Nashwa F. El-Tahawy

“…Tramadol decreased the levels of serum cortisol and DHEAS hormones. In addition, it increased the level of adrenal MDA and decreased the genetic expression of glutathione peroxidase and thioredoxin reductase in adrenal gland tissues. …”
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Jesus uttering his last words and drawing on his final breath: reflecting on Luke 23:46 by P. Nagel

“…The purpose of this reflection is to come to a deeper appreciation of his death, with the hope that it might mean something to someone struggling to breathe while dying. …”
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Lithium Carbonate in the Treatment of Graves’ Disease with ATD-Induced Hepatic Injury or Leukopenia by Rendong Zheng, Kemian Liu, Kun Chen, Wen Cao, Lin Cao, Huifeng Zhang, Hongping Sun, Chao Liu

“…After treatment for 36 weeks, symptoms of hyperthyroidism and the level of thyroid hormones were improved and liver function, and white blood cells returned to a normal level. …”
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The Role of “Mixed” Orexigenic and Anorexigenic Signals and Autoantibodies Reacting with Appetite-Regulating Neuropeptides and Peptides of the Adipose Tissue-Gut-Brain Axis: Releva... by Kvido Smitka, Hana Papezova, Karel Vondra, Martin Hill, Vojtech Hainer, Jara Nedvidkova

“…The gut-brain-adipose tissue (AT) peptides and neutralizing autoantibodies play an important role in the regulation of eating behavior and growth hormone release. The mechanisms for controlling food intake involve an interplay between gut, brain, and AT. …”
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Corrosion Resistance Synergistic Appraisal of Titanium-Impregnated Bisphenol A-Type Epoxy Duplex Coating System in Stimulated and Natural Marine Environments of Southeastern Coasta... by Ishrat Jamil, Humaira Bano, Vinod C. Malshe, Azhar Mahmood, Kamran Khan, Nasir M. Ahmad

“…In addition, these Ti microparticles have filled up the cavities/imperfections, reduced cracking, promoted crosslinking during the curing, and cordoned-off passage of corrodents and moisture, thus improving epoxy resin coating features. …”
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Biological factors controlling starch digestibility in human digestive system by Cheng Li, Yiming Hu, Songnan Li, Xueer Yi, Shuaibo Shao, Wenwen Yu, Enpeng Li

“…Main biological factors are summarized as oral mastication and salivation, gastric emptying and motility, small intestinal enzymes and motility, large intestinal resistant starch (RS)-microbiota interactions and gut-brain feedback control, as well as glucose adsorption and hormonal feedback control. However, connections among these biological factors in determining starch digestive behaviors remain elusive. …”
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A Rare Presentation of Primary Hyperparathyroidism with Concurrent Aldosterone-Producing Adrenal Carcinoma by Mario Molina-Ayala, Claudia Ramírez-Rentería, Analleli Manguilar-León, Pedro Paúl-Gaytán, Aldo Ferreira-Hermosillo

“…Biochemical assessment showed a mildly elevated calcium (11.1 mg/dL), high parathyroid hormone, and a plasma aldosterone concentration/plasma renin activity ratio of 124.5 (normal < 30), compatible with primary hyperparathyroidism with a concomitant primary hyperaldosteronism. …”
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Molecular simulations reveal intricate coupling between agonist-bound β-adrenergic receptors and G protein by Yanxiao Han, John R.D. Dawson, Kevin R. DeMarco, Kyle C. Rouen, Khoa Ngo, Slava Bekker, Vladimir Yarov-Yarovoy, Colleen E. Clancy, Yang K. Xiang, Surl-Hee Ahn, Igor Vorobyov

“…Summary: G protein-coupled receptors (GPCRs) and G proteins transmit signals from hormones and neurotransmitters across cell membranes, initiating downstream signaling and modulating cellular behavior. …”
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