Association between magnesium depletion score and prevalence of hyperuricemia in American adults: a study based on NHANES 2007-2018 by Yongchun Xiao, Yong Mou, Yong Mou, Ping Wu, Ke Wang, Tianjun Chen, Zhiwan Chen, Hongsheng Lin, Hua Yang, Zhisheng Ji

“…Multivariable logistic regression confirmed a significant positive association between MDS and HUA (OR = 1.73, 95% CI = 1.62-1.84). Restricted cubic splines (RCS) further characterized the non-linear relationship between MDS and HUA prevalence. …”
Get full text

Combined exposure to mixed brominated flame retardants on obstructive sleep apnea syndrome in US adults by Junping Liu, Zhaoyue Liu, Xinru Liu, Nan Wang, Lin Wu, Xiaoxue Xu, Wei Liu, Yajie Feng, Huanyu Zhang, Yue Zhou, Xinle Yin, Yaping Liu, Qunhong Wu, Ning Ning, Libo Liang

“…To investigate the OSAS risk with BFRs exposure, multivariate logistic regression, weighted quantile sum (WQS) regression, quantile g-computation (QGC), Bayesian kernel machine regression (BKMR) models, and restricted cubic splines (RCS) were implemented. Results Serum BFRs, including PBDE28, PBDE47, PBDE99, PBDE100, and PBB153, showed positive correlations with the OSAS risk. …”
Get full text

Association between the dietary inflammatory index and depressive symptoms in adults with metabolic syndrome: a cross-sectional study from the NHANES database by Jinshun You, Jinshun You, Shujie Xia

“…Subgroup analyses and restricted cubic splines (RCS) were performed to explore this relationship further.ResultsAmong the participants, 907 individuals (12.0%) were identified as having depressive symptoms. …”
Get full text

Associations between phenol and paraben exposure and the risk of developing breast cancer in adult women: a cross-sectional study by Yao Xiong, Zhiyu Li, Xiong Xiong, Zixuan Luo, Kaixin Zhong, Jiawei Hu, Shengrong Sun, Chuang Chen

“…The nonlinear association between TRS concentrations and the risk of developing BC was statistically significant (P nonlinear = 0.007), with the restricted cubic splines (RCS) curve exhibiting an inverted U shape. …”
Get full text

Serum hydroxycotinine was associated with chronic kidney disease (CKD): a cross-sectional study based on NHANES by Meng’en Zhu, Zhimin Bi, Yaoling Wang, Wei Li

“…The non-linear relationship was explored with restricted cubic splines (RCS). Pearson’s correlation coefficient and a multivariate logistic regression model were used for correlation analysis.Results Serum hydroxycotinine and eGFR were negatively correlated in both non-CKD group (r= −0.05, p < 0.001) and CKD group (r= −0.04, p < 0.001). …”
Get full text

The association between obesity indicators and mortality among individuals with hyperlipidemia: evidence from the NHANES 2003–2018 by Yiheng Zhang, Yajun Yao

“…Weighted Cox regression models and restricted cubic splines (RCS) were employed to assess the potential links between obesity indicators and mortality outcomes. …”
Get full text

Inadequate Lymph Node Yield: An Inadequate Indication for Adjuvant Chemotherapy in Stage II Colon Cancer by Alan Zambeli-Ljepović, MD, MHS, Daniel Hoffman, MD, Katherine E. Barnes, BS, Fernanda Romero-Hernandez, MD, Amir Ashraf Ganjouei, MD, MPH, Mohamed A. Adam, MD, Ankit Sarin, MD, MHA

“…We used Cox proportional hazards models to assess overall survival and restricted cubic splines to estimate the optimal LNY threshold to dichotomize patients based on overall survival. …”
Get full text

Association between neutrophil-albumin ratio and ultrasound-defined metabolic dysfunction-associated fatty liver disease in U.S. adults: evidence from NHANES 2017–2018 by Ming-yu He, Xin-jie Du, Yi-ming Liu

“…A generalized additive model (GAM) and restricted cubic splines (RCS) were applied to explore the nonlinear relationship between NAR and CAP, followed by generalized linear models (GLMs). …”
Get full text

Comparative analysis of sloshing effects on elevated water tanks’ dynamic response using ANN and MARS by Tahera, Neethu Urs, K. Shashi Raj, Rakesh Kumar, Harish Soundalgekar, T. Deepa, Mohd Asif Shah

“…Multivariate Adaptive Regression Splines (MARS) and Artificial Neural Network (ANN) models were created and trained in order to further examine and forecast the dynamic response. …”
Get full text

Association of LDL‐C/HDL‐C Ratio With Hyperuricemia: A National Cohort Study by Yanyu Zhang, Xiaoyi Liu, Deyun Luo, Bingli Chen, Chenyi Lai, Chenyu He, Luo Yan, Haifeng Ding, Shiyang Li

“…Multivariable logistic regression, restricted cubic splines (RCSs) analysis, and linear correlation analysis were conducted to evaluate the association between LHR and risk of developing HUA. …”
Get full text

Relationship of METS-IR with cardiometabolic multimorbidity in China: a nationwide longitudinal cohort study by Chunyan Zhou, Yanyu Zhang, Xiaoyi Liu, Chenyu He, Shiyang Li, Shiyang Li

“…We used multiple cox proportional hazards regression and restricted cubic splines (RCS) analysis to evaluate the association between METS-IR and CMM. …”
Get full text

Adverse childhood experiences, sleep quality/duration and later-life lower extremity function among older adults in China: evidence from CHARLS by Jiaqiang Xiao, Xiaosheng Dong, Meng Ding, Tao Kong

“…The relationships between ACEs, sleep, and lower extremity function were analyzed using multivariate linear regression model and restricted cubic splines. Results After adjusting for covariates, older adults with four or more ACEs exhibited worse lower extremity function compared to those with no ACEs (β: -0.175). 6–8 h of sleep was associated with improved lower extremity function (β: 0.119), while good sleep quality was also associated with higher lower extremity function scores (β: 0.177). …”
Get full text

Estimated Pulse Wave Velocity Is Associated With All‐Cause Mortality and Cardiovascular Mortality Among Adults With Chronic Kidney Disease by Xiao‐Hua Feng, Yi Chen, Xue‐Qi Chen, Wei‐Hong Zhao

“…Linear testing between ePWV and mortality from all causes and CVD was performed using restricted cubic splines and Cox regression. This study included 4669 patients with CKD from the NHANES, representing 37 million Americans with CKD. …”
Get full text

U-shaped association between TC/HDL-C ratio and osteoporosis risk in older adults by Chuanwei Zhao, Xiaochun Zhang, Xu Zhang, Bo Zhao, Yane Yang, Mu Lin, Wenli Qiao, Zeyao Hu, Haijie Yang

“…Multivariable logistic regression models assessed the association between the TC/HDL-C ratio and osteoporosis prevalence. Restricted cubic splines were used to explore non-linear associations and threshold effects. …”
Get full text

The association between visceral fat metabolic score and stroke: mediation by declining kidney function by Yue Cao, Weixing Wen, Hao Zhang, Weiwen Li, Guolin Huang, Yuli Huang

“…Weighted logistic regression models were used to assess the association between METS-VF and stroke risk, with restricted cubic splines employed to explore their non-linear relationships. …”
Get full text

The triglyceride–glucose index and its obesity-related derivatives as predictors of all-cause and cardiovascular mortality in hypertensive patients: insights from NHANES data with... by Chenyang Li, Zixi Zhang, Xiaoqin Luo, Yichao Xiao, Tao Tu, Chan Liu, Qiming Liu, Cancan Wang, Yongguo Dai, Zeying Zhang, Cheng Zheng, Jiafeng Lin

“…Cox proportional hazards models and restricted cubic splines were employed to explore mortality risk and potential nonlinear relationships. …”
Get full text

Epicardial Adipose Tissue and Left Ventricular Hypertrophy in Hypertensive Patients With Preserved Ejection Fraction: A Multicenter Retrospective Cohort Study by Runze Zhu, Wenxian Wang, Yan Gao, Junchuan Liu, Bowen Li, Rongxue Shan, Runjie Xue, Xianshun Yuan, Xi‐Ming Wang

“…Postprocessing and imaging analysis were conducted and EAT measurements were performed. Restricted cubic splines (RCS) were used to explore the potential relationship with LVH. …”
Get full text

Multi-metal mixture exposure and cognitive function in urban older adults: The mediation effects of thyroid hormones by Zhuoqi Zhu, Juanhua Li, Yang Peng, Ning Qin, Jiemei Li, Ying Wei, Biwen Wang, Yunfei Liao, Huaicai Zeng, Lu Cheng, Han Li

“…Nonlinear inverse U-shaped associations between Mo, Rb, and MMSE scores were identified using Restricted Cubic Splines (RCS) and Bayesian Kernel Machine Regression (BKMR). …”
Get full text

Relationship between TyG-related index and hearing loss in people over 45 s in China by Chao Wang, Mengdi Shi, Liangzhen Xie, Chenhao Jiang, Yunxin Li, Jingxiao Li, Shulin Li, Yan Li

“…We applied multi-factor logistic regression, linear regression, restricted cubic splines, and subgroup analyses to assess the impact of the TyG index, BMI index, and TyG-BMI index on hearing loss across different age groups.ResultsThe TyG index was not significantly associated with hearing loss. …”
Get full text

Relationship between prenatal metals exposure and neurodevelopment in one-year-old infants in the CLIMB study by Xiao-Yuan Fan, Xian-Shu Lin, Bing-Rui Yang, Han-Wen Zhang, Feng Tang, Jia-Jia Tang, He-Bin Chi, Toby Mansell, Noora Kartiosuo, Yin-Yin Xia, Ting-Li Han, Hua Zhang, Philip Baker, Richard Saffery

“…Multiple statistical methods, including linear models, restricted cubic splines (RCS), weighted quantile sum (WQS) regression, and Bayesian kernel machine regression (BKMR). …”
Get full text