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Changes in Physical Activity Across Cancer Diagnosis and Treatment Based on Smartphone Step Count Data Linked to a Japanese Claims Database: Retrospective Cohort Study
Published 2025-01-01“…We applied a generalized additive mixed model with a cubic spline to describe changes in step counts before and after diagnosis. …”
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Prognostic value of neutrophil-to-lymphocyte ratio dynamics in patients with septic acute kidney injury: a cohort study
Published 2024-12-01“…The relationship between the ΔNLR and mortality was evaluated by Kaplan–Meier curves, Cox proportional hazards, and cubic spline analyses. The prediction values were compared by area under the receiver-operating characteristic curve (AUROC), net reclassification improvement (NRI), and integrated discrimination improvement (IDI) analyses.Results Of the 413 participants, the mean age was 63 ± 17 years, and 134 were female (32.4%). …”
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Low albumin-to-creatinine ratios (ACR) are associated with poor outcomes in cancer patients
Published 2025-01-01“…Correlation analysis, Kaplan–Meier method, and restricted cubic spline analysis were conducted to explore ACR's relationship with overall survival (OS). …”
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Nonlinear association between glycated hemoglobin levels and mortality in elderly patients with non-diabetic chronic kidney disease: a national health and nutrition examination sur...
Published 2025-02-01“…Hazard ratios (HR) and 95% confidence intervals (CIs) for all-cause and CVD mortality were calculated using weighted Cox proportional hazards and restricted cubic spline models.ResultsAmong the 1,931 participants (mean [SE] age, 73.2 [0.2] years; 61.9% female), over a median follow-up period of 7.6 years, a total of 1,003 deaths were observed, including 412 from CVD. …”
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Association between various blood glucose variability-related indicators during early ICU admission and 28-day mortality in non-diabetic patients with sepsis
Published 2025-01-01“…The dose-response relationship between BG variability-related indexes and mortality was explored using multivariate logistic regression with restricted cubic spline (RCS) function. If the dose-response curve presented a J-shape with a specific threshold value, a linear threshold function instead of RCS would be employed. …”
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Association between glyphosate exposure and cardiovascular health using “Life’s Essential 8” metrics in US adults
Published 2025-01-01“…The association between natural logarithm (ln)-transformed glyphosate exposure in urine and CVH was examined using weighted linear regression and restricted cubic spline (RCS) models. Mediation analysis was used to determine potential mediators correlated with glyphosate and CVH. …”
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Correlation between liver fibrosis in non-alcoholic fatty liver disease and insulin resistance indicators: a cross-sectional study from NHANES 2017–2020
Published 2025-01-01“…To assess the association between multiple IR indicators and LF, the study methodology included univariate and multivariate logistic regression, as well as restricted cubic spline (RCS) analysis. Subsequently, we used multivariate logistic regression to develop and validate a predictive model for LF, and evaluated the model’s performance using the area under the curve (AUC) and calibration curve.ResultsA total of 904 patients were included in the final analysis. …”
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Spironolactone Protects against Diabetic Cardiomyopathy in Streptozotocin-Induced Diabetic Rats
Published 2018-01-01Get full text
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Association of lung health and cardiovascular health (Life’s Essential 8)
Published 2025-02-01“…Weighted multivariate regression analyses examined the correlations between LE8 and lung health, and weighted restricted cubic spline (RCS) regression analyzed potential non-linear relationships. …”
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A Prospective, Randomized Comparison of Duodenoscope Reprocessing Surveillance Methods
Published 2019-01-01Get full text
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