The systemic oxidative stress index predicts clinical outcomes of esophageal squamous cell carcinoma receiving neoadjuvant immunochemotherapy by Jifeng Feng, Jifeng Feng, Liang Wang, Xun Yang, Qixun Chen, Qixun Chen

“…Given the non-linear relationship between SOSI and DFS, the best threshold was determined using a restricted cubic spline (RCS) model. Independent variable determination was executed using a cox regression analysis. …”
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Risedronate Attenuates Podocyte Injury in Phosphate Transporter-Overexpressing Rats by Yohei Asada, Takeshi Takayanagi, Tsukasa Kawakami, Eisuke Tomatsu, Atsushi Masuda, Yasumasa Yoshino, Sahoko Sekiguchi-Ueda, Megumi Shibata, Tomihiko Ide, Hajime Niimi, Eishin Yaoita, Yusuke Seino, Yoshihisa Sugimura, Atsushi Suzuki

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Fractionation of Rare Earth Elements in Greisen and Hydrothermal Veins Related to A-Type Magmatism by Mikael Tillberg, Olga M. Maskenskaya, Henrik Drake, Johan K. Hogmalm, Curt Broman, Anthony E. Fallick, Mats E. Åström

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Serum Uric Acid and Bone Health in Middle-Aged and Elderly Hypertensive Patients: A Potential U-Shaped Association and Implications for Future Fracture Risk by Shuaiwei Song, Xintian Cai, Junli Hu, Qing Zhu, Di Shen, Huimin Ma, Yingying Zhang, Rui Ma, Pan Zhou, Wenbo Yang, Jing Hong, Nanfang Li

“…Dose–response relationship analysis was conducted using generalized smooth curve fitting (GSCF) and restricted cubic spline (RCS) methods. Results: With the exception of the total femur region, SUA and BMD showed a positive connection. …”
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Association of alcohol abstinence with risk of hyperuricemia in rural Chinese adults: the Henan Rural Cohort Study by Xiaokang Dong, Lulu Zhang, Ning Kang, Huanxiang Zhang, Wei Liao, Xiaotian Liu, Pengling Liu, Lei Yin, Chongjian Wang

“…Multivariate logistic regression analyses were used to evaluate the associations of type of alcoholic beverages, abstinence status and abstinence duration with HUA, respectively. Restricted cubic spline models were applied to visualize the dose-response trend of HUA risk with increasing abstinence duration. …”
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Examined lymph node counts affected the staging and survival in cervical cancer: a retrospective study using the SEER and Chinese cohort by Tao Guo, Yuxi Zhao, Jia Zeng, Jian Li, Enyu Tang, Lingying Wu

“…Multivariable logistic and Cox regression models assessed LN positivity detection and overall survival (OS), respectively. Smoothing spline curves and Chow tests identified structural change points in hazard ratios and LN-positive ratios.Results Among 14,133 SEER and 2,811 Chinese cases, higher LN counts correlated with increased detection of positive LNs (OR: 1.040, 95% CI: 1.019–1.062) and improved OS (HR: 0.990, 95% CI: 0.984–0.996). …”
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Discovery of Novel Diagnostic Biomarkers for Common Pathogenic <i>Nocardia</i> Through Pan-Genome and Comparative Genome Analysis, with Preliminary Validation by Chaohong Wang, Xinmiao Jia, Ming Wei, Jun Yan, Qing Sun, Sibo Long, Maike Zheng, Yiheng Shi, Guanglu Jiang, Yan Zhao, Hairong Huang, Xinting Yang, Li Gu, Guirong Wang

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Association between the low-density lipoprotein to high-density lipoprotein ratio and prognosis in critically ill intracerebral hemorrhage patients: a retrospective cohort study fr... by Yuchen Liu, Houxin Fu, Yue Wang, Yi Zhong, Rongting Zhang, Jingxuan Sun, Tianquan Yang, Yong Han, Yongjun Xiang, Bin Yuan, Ruxuan Zhou, Min Chen, Hangzhou Wang

“…Additionally, restricted cubic spline (RCS), subgroup, and sensitivity analyses were conducted to further validate our findings. …”
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Identification of a postoperative survival scoring index for adult liver transplantation by Shuai Wang, Xiaohong Lin, Yefu Li, Zhonghao Xie, Ming Zhang, Yicheng Liang, Chuchen Zhu, Yuqi Dong, Ping Zeng, Xiaoshun He, Weiqiang Ju, Maogen Chen

“…The postoperative survival score (POSS) index was further simplified via restricted cubic spline (RCS) analysis. Finally, the interpretation of the long-term mortality and subgroup analyses extended the application of the POSS index.Results Finally, a total of five factors (donor sex, recipient body mass index (BMI), total bilirubin (Tbil), international normalized ratio (INR) and total operative time) were identified as independent risk parameters and included in our POSS index. …”
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Association between ethylene oxide exposure and osteoarthritis risk: an analysis of NHANES data (2013–2014 and 2017–2018) by Zhongshan Li, Zhongshan Li, Qi Qu, Qi Qu, Zhiyu Wang, Zhiyu Wang, Shuanglin Mou, Rui Jiang, Rui Jiang, Wensheng Zhu, Wensheng Zhu

“…Weighted logistic regression models and restricted cubic spline (RCS) models were used to evaluate the relationship between EO exposure and OA risk. …”
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Comparative effect of atorvastatin and risperidone on modulation of TLR4/NF-κB/NOX-2 in a rat model of valproic acid-induced autism by Eman A. E. Farrag, Mona H. Askar, Zienab Abdallah, Safinaz M. Mahmoud, Eman A. Abdulhai, Eman Abdelrazik, Eman Mohamad El Nashar, Faten Mohammed Alasiri, Asma Nasser Saeed Alqahtani, Mamdouh Eldesoqui, Ali M. Eldib, Alshimaa Magdy

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Primordial Germ Cells Quality of Chicken Embryo from Post Cryopreservation Blood Samples by Nurul Azizah, Tatan Kostaman, Yuli Arif Tribudi, Diana Andrianita Kusumaningrum, Suyatno Suyatno, Zultinur Muttaqin, Eko Koswara, Muhammad Gunawan

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Knowledge, attitude and practice regarding screening and managing diabetic microvascular complications among general practitioners of community health centres: a cross-sectional st... by Hua Yang, Jian Gao, Ying Yu, Cuiling Huang, Chengdian Lan, Zhangyan Chen

“…Multiple stepwise linear regression was used to explore the influencing factors of KAP. Restricted cubic spline curves with four knots (5%, 35%, 65%, 95%) were used to determine the association between KAP score and duration of general practice.Results A total of 1243 questionnaires were included in the analysis. …”
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The association of body roundness index and body mass index with frailty and all-cause mortality: a study from the population aged 40 and above in the United States by Jianqiang Zhang, Huifeng Zhang

“…Based on weighted logistic regression, COX regression and restricted cubic spline, the associations of BRI and BMI with the odds of frailty and the risk of all-cause mortality were estimated. …”
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Malnutrition risk, weight loss, and subsequent survival in patients listed for heart transplantation by Tae Kyung Yoo, MD, MS, Satoshi Miyashita, MD, Ariella Stein, MSCIS-HI, Michael Wu, BS, MPH, Lauren Parsly Read-Button, MPH, RD, LDN, Masashi Kawabori, MD, Greg S. Couper, MD, Edward Saltzman, MD, Amanda R. Vest, MBBS, MPH

“…We constructed Cox proportional hazards models and restricted cubic spline curves for each risk score at both HT listing and HT operation and inputted HT operation as a time-varying covariate for models commencing at listing. …”
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Effects of Gestational Inflammation with Postpartum Enriched Environment on Age-Related Changes in Cognition and Hippocampal Synaptic Plasticity-Related Proteins by Shi-Yu Sun, Xue-Yan Li, He-Hua Ge, Yu-Xin Zhang, Zhe-Zhe Zhang, Zhan-Qiang Zhuang, Chong-Yang Ren, Fang Wang, Gui-Hai Chen

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Relationship between stress hyperglycemia ratio and progression of non target coronary lesions: a retrospective cohort study by Shiqi Liu, Ziyang Wu, Gaoliang Yan, Yong Qiao, Yuhan Qin, Dong Wang, Chengchun Tang

“…Logistic regression models, restricted cubic spline analysis, and machine learning algorithms (LightGBM, decision tree, and XGBoost) were utilized to analyse the relationship of stress hyperglycemia ratio and non target lesion progression. …”
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Predicting High-Grade Acute Urinary Toxicity and Lower Gastrointestinal Toxicity After Postoperative Volumetric Modulated Arc Therapy for Cervical and Endometrial Cancer Using a No... by Tianyu Yang, Zhe Ji, Runhong Lei, Ang Qu, Weijuan Jiang, Xiuwen Deng, Ping Jiang

“…The normal tissue complication probability (NTCP) model was established using the logistic regression model. Restricted cubic spline (RCS) curves were used to explore the association between dosimetric parameters and toxicities. …”
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The Association Between the CALLY Index and All-Cause Mortality in Patients with COPD: Results from the Cohort Study of NHANES 2007&ndash;2010 by Ding Y, Liu Y, Yu J, Cai C, Fu L, Zhu J, Yang S, Jiang Y, Wang J

“…The study utilized Kaplan-Meier curves, restricted cubic spline (RCS) curves, and Cox regression analysis to evaluate the relationship between the CALLY index and the risk of all-cause mortality in COPD patients. …”
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Effect of colchicine on physiological and biochemical properties of <i>Rhodococcus qingshengii</i> by Yu. A. Markova, L. A. Belovezhets, V. N. Nurminsky, I. S. Kapustina, N. V. Ozolina, V. V. Gurina, A. L. Rakevich, A. V. Sidorov

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