Tasquinimod suppresses tumor cell growth and bone resorption by targeting immunosuppressive myeloid cells and inhibiting c-MYC expression in multiple myeloma by Marie Törngren, Rong Fan, Eline Menu, Helena Eriksson, Karin Vanderkerken, Andrew Chantry, Hatice Satilmis, Niels Vandewalle, Emma Verheye, Philip Vlummens, Anke Maes, Catharina Muylaert, Elke De Bruyne, Holly Evans, Nathan De Beule, Dirk Hose, Ken Maes, Karine Breckpot, Kim De Veirman

“…Tasquinimod-mediated targeting of the myeloid cell population resulted in increased T cell proliferation and functionality in vitro. Notably, short-term tasquinimod therapy of 5TMM mice significantly increased the total CD11b+ cells and shifted this population toward a more immunostimulatory state, which resulted in less myeloid-mediated immunosuppression and increased T cell activation ex vivo. …”
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Postoperative Complications After Operative Treatment of Open Versus Closed Distal Radius Fractures: A Propensity Score Matched Analysis by R. Cole Schmidt, MD, Conor N. O’Neill, MD, Zakkary J. Walterscheid, MD, James R. Satalich, MD, Jonathan Isaacs, MD

“…This suggests that many OF patients do not carry a clinically increased short-term risk of infection when compared to CF patients. …”
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Captive breeding, developmental biology and commercial production of<i> Dravidia fasciata</i>- An indigenous ornamental fish of the Western Ghats of India by T.V. Anna Mercy, Eapen Jacob, K. Raju Thomas

“…Hence many times, the demand could not be met due to short supply. The only remedial measure for a sustainable supply is to produce the fish in captive conditions. …”
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The impact of drought on forest spring phenology in northern China by Haowen Hu, Pengcheng Xue, Shaodong Huang, Zong Wang, Nina Xiong, Liang Shi, Boyi Liang, Jia Wang

“…SOS in the four hydroclimatic regions showed an average trend of advancement, with an average advancement of 0.31 days per year. (2) The impact of pre-season drought on SOS in forests across four study regions exhibits an intriguing pattern. Short-term pre-season drought significantly influences spring phenology. …”
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New‐Occurrence of Postoperative Modic Changes and Its Influence on the Surgical Prognosis After Percutaneous Endoscopic Lumbar Disc Discectomy by Lei Li, Chao Wang, Hao Zhang, Zhiming Liu, Zheng Lian, Han Li, Hao Tao, Xuexiao Ma

“…Conclusion The postoperative MCs, as a risk factor, may have a detrimental effect on the surgical efficacy and short‐term recurrence of LDH following PELD based on a large sample. …”
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Web-based interventions for pregnant women with gestational diabetes mellitus: a systematic review and meta-analysis protocol by Ping Xu, Wei Zhang, Xiaojuan Wang, Dan Dan Chen, Pingping Guo, Yin Jin, Zhenzhen Xiang, Minna Mao, Qiong Zheng, Suwen Feng

“…Introduction Gestational diabetes mellitus (GDM) is one of the most prevalent diseases during pregnancy, which is closely associated with many short-term and long-term maternal and neonatal complications and can incur heavy financial burden on both families and society. …”
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Sacubitril/valsartan is associated with improvements in quality of life in adult congenital heart disease patients with systemic right ventricular failure by Philippine Kiès, Marieke Nederend, Ralph M.L. Neijenhuis, Anna E. van Groningen, Monique R.M. Jongbloed, Hubert W. Vliegen, J. Wouter Jukema, Anastasia D. Egorova

“…Background Short-term improvements in quality of life (QOL) have been reported in adult congenital heart disease patients with systemic right ventricle (sRV) failure after treatment with sacubitril/valsartan. …”
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Estimating the Effect of Adhering to the Recommendations of the 2019 Canada’s Food Guide on Health Outcomes in Older Adults: Protocol for a Target Trial Emulation by Didier Brassard, Nancy Presse, Stéphanie Chevalier

“…Although ideal, conducting a large randomized controlled trial is unrealistic in the short term. An alternative is the target trial emulation framework for causal inference, a novel approach to improve the analysis of observational data. …”
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Principles to award learning achievements for lifelong learning in health using micro-credentials: an international Delphi study by Sharon Mitchell, John Hart, Muntaha Gharaibeh, Graham T. McMahon, Anthea Rhoda, Siobhan Fitzpatrick, Tana Wuliji, Janusz Janczukowicz

“…The interest in alternative pathways to award health practitioners, through short competency-based micro-learning opportunities, has spurred discussions on the practical application of micro-credentials. …”
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Urban vegetation benefits in mediterranean cities for climate change adaptation and water usage efficiency – a case study in Algarve, Portugal by Pedro Matias, Pedro Matias, Pedro Matias, Manuela Moreira da Silva, Manuela Moreira da Silva, Manuela Moreira da Silva, João Teigão, Amílcar Duarte, Amílcar Duarte

“…In the current climate change scenario, Mediterranean cities face heatwaves and reduced availability of freshwater alternated with intense precipitation events in short periods. The demand for water, especially for urban and tourism purposes, is rising, particularly in coastal cities. …”
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Predictors of physical and mental health among unemployed people in Greece by Dimitra Latsou, Mary Geitona

“…Results: The mean age of participants was 35.8 ± 10.3 years, 66.1% were women and 71.8% was short-term unemployed. The mean VAS before unemployment was 85 ±13.6, which decreased to 68.3 ±23.1 during unemployment (P = 0.001) and 55.2% of the sample suffered from depressive symptoms. …”

Investigating ITM2B‐associated ataxia in a Taiwanese cerebellar ataxia cohort by Shih‐Yu Fang, Cheng‐Tsung Hsiao, Kang‐Yang Jih, Yu‐Sheun Tsai, Kuan‐Lin Lai, Cheng‐Ta Chou, Yi‐Chu Liao, Yi‐Chung Lee

“…Methods Genetic analysis of ITM2B was performed in 212 unrelated Taiwanese patients with unsolved cerebellar ataxia. Eight short tandem repeat markers flanking ITM2B were genotyped to analyze the associated haplotype. …”
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Comparison of Brain-Behavioral Systems, Decision Making Styles and Cognitive Emotion Regulation in Adults with and without ADHD by Asiyeh Vakia, Reza Soltani Shal, Abbas Abolghasemi

“…The research tools utilized in this study included the World Health Organization Adult Attention Deficit Hyperactivity Disorder Self-Rating Scale (ASRS), the Brain/Behavioral Systems Questionnaire (BAS-BIS), the General Decision-Making Styles Questionnaire (GDMS), and the Short Form of the Cognitive Emotion Regulation Questionnaire (CERQ). …”
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Current trends, methods and results of brown mustard (Brassica juncea) and black mustard (Brassica nígra) breeding by V. S. Trubina

“…In competitive trials ‘Niagara’ demonstrated an average yield at the level of 1.5–1.7 t/ha, and the oil content in seeds of 37.0–40.0%. Cv. ‘Niagara’ has a short growing season.…”
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Enhanced multifaceted model for plasmon-driven Schottky solar cells with integrated thermal effects by Brahim Aïssa, Ahmer A. Baloch, Adnan Ali, Anirban Mitra

“…The findings indicated that the 5 × 5 NP array with a 70 nm radius enhances electrical performance, with the short-circuit current density (Jsc) reaching 11.54 mA/cm2—A 47% improvement compared to traditional bare silicon Schottky cells of 2 μm thickness. …”
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The Effects of 1 mA tACS and tRNS on Children/Adolescents and Adults: Investigating Age and Sensitivity to Sham Stimulation by Maike Splittgerber, Jan Hendrik Suwelack, Navah Ester Kadish, Vera Moliadze

“…Single-pulse MEPs (motor evoked potential), short-interval intracortical inhibition, and facilitation were measured by TMS before and after stimulation (baseline, 0, 30, 60 minutes). …”
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P2P and MPEG FGS Encoding: A Good Recipe for Multipoint Video Transmission on the Internet by Alfio Lombardo, Diego Reforgiato, Giovanni Schembra

“…In the proposed system the source generates the video flow by using an MPEG-4/FGS encoder, in such a way that no losses occur at the Baselayer stream even in the presence of short-term bandwidth fluctuations. Although in the past the FGS was not employed due to its encoding complexity, today, thanks to advances in hardware technology, we were able to develop an MPEG-4/FGS encoder on low-cost PCs which turned out to be more feasible and appealing for its flexibility. …”
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Clofarabine induces tumor cell apoptosis, GSDME-related pyroptosis, and CD8+ T-cell antitumor activity via the non-canonical P53/STING pathway by Jing Chen, Jie Wu, Xiang Chen, Qian Tao, Nian Liu, Cong Peng, Can Lu, Qiuqiu Li

“…The molecular mechanisms of Clo-induced tumor cell death were analyzed using western blotting, ELISA, reverse transcription-PCR, immunofluorescence, co-immunoprecipitation (CO-IP), short hairpin RNA, co-culture, chromatin immunoprecipitation, and flow cytometry. …”
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Surgical treatment of Hallux Rigidus – arthrodesis or resection arthroplasty? Retrospective observational study by Dovydas Rapolis, Matas Urmanavičius, Aleksas Makulavičius, Valentinas Uvarovas

“…Patients’ quality of life and subjective foot function were assessed using two standardized questionnaires: SEFAS and Short Form-12. Additional questions on patient satisfaction with the surgery were also evaluated. …”
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A Study on Dust Storm Pollution and Source Identification in Northwestern China by Hongfei Meng, Feiteng Wang, Guangzu Bai, Huilin Li

“…To mitigate the impacts of future dust storms, this study highlights both short-term and long-term strategies, including enhanced monitoring systems, public health advisories, and vegetation restoration in key source regions. …”
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