Multi-decade northward shift of loggerhead sea turtle pelagic habitat as the eastern North Pacific Transition Zone becomes more oligotrophic by Dana K. Briscoe, Dana K. Briscoe, Larry B. Crowder, George H. Balazs, Jeffrey A. Seminoff, Alberto Abreu, Catherine A. Lee Hing, Masanori Kurita, Masanori Mori, Denise M. Parker, Marc R. Rice, Tomomi Saito, Bianca S. Santos, Calandra N. Turner Tomaszewicz, Noah Yamaguchi, Jeffrey J. Polovina

“…Although it is anticipated that many highly mobile species will need to adapt and shift their distributions, current predictions have relied on short-term data sets or modeled simulations. This has left a critical gap in our understanding of long-term (decadal or longer) change and species’ responses within the NPTZ. …”
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A self-assembled nanoparticle vaccine elicits effective neutralizing antibody response against EBV infection by Ping Li, Ping Li, Ziyi Jiang, Jingjing Shi, Haochuan Sha, Zihang Yu, Yan Zhao, Sanyang Han, Lan Ma, Lan Ma, Lan Ma

“…These epitope peptides detected a binding capability with host cells were then fused by flexibility linkers and expressed in Escherichia coli to reduce the unnecessary glycan modifications to simulate their free-glycan status. The fused recombinant protein (L350) was displayed on the surface of ferritin-based nanoparticle. …”
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Reconstructing prevalence dynamics of wildlife pathogens from pooled and individual samples by Borremans, Benny, Falvo, Caylee A, Crowley, Daniel E, Hoegh, Andrew, Lloyd-Smith, James O, Peel, Alison J, Restif, Olivier, Ruiz-Aravena, Manuel, Plowright, Raina K

“…Last, the model enables estimation of extrinsic environmental effects on prevalence dynamics. Using a simulated dataset inspired by virus transmission in flying foxes, we show that the model is able to accurately estimate prevalence dynamics, false negative rate, and covariate effects. …”
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A flood resilience assessment method of green-grey-blue coupled urban drainage system considering backwater effects by Yue Liu, Xiang Zhang, Jie Liu, Yao Wang, Haifeng Jia, Shiyong Tao

“…The method offers a way to quantify the backwater effect of blue infrastructure in conditions where hydrological and hydraulic models cannot efficiently simulate the situation, by introducing the Potential Flooding Area Ratio (PFAR). …”
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Influence of low-level laser radiation on the physico-chemical indicators of biomembranes by Л. В. Січевська, Т. M. Овсяннікова, А. О. Коваленко, І. А. Забєліна, О. М. Левченко, О. В. Гурін, В. П. Берест

“…Materials and methods: Research objects: unicellular organisms S. cerevisiae, concentration of cells in the sample 18×106; model lipid membranes from a mixture of phosphatidylcholine and cardiolipin with different content of components (10%, 20% and 40% cardiolipin), which simulates the surface electrical properties of lipid models. …”
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Time-series forest age estimation in Xinjiang based on forest disturbance and recovery detection by Lili Zhai, Mei Zan, Mao Ye, Jia Zhou, Cong Xue, Shunfa Yang, Yuntong Liu

“…The findings revealed that: (1) the R2 values of the RF regression models for estimating forest age exceeded 0.65, with RMSEs below 22 years and RRMSEs ranging from 0.119 to 0.183, demonstrating high credibility of the simulation results; (2) the overall accuracy of the LandTrendr algorithm in identifying forest loss and gain in the study area was 85 % or higher. …”
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Simultaneous non-contrast assessment of cardiac microstructure and perfusion in vivo in the human heart by Camila Munoz, Eunji Lim, Pedro F. Ferreira, Dudley J. Pennell, Sonia Nielles-Vallespin, Andrew D. Scott

“…STEAM-IVIM imaging was performed at 20 b-values (0 to 1000 s/mm2) to enable accurate estimation of the IVIM parameters, and with six diffusion encoding directions to enable reconstruction of the diffusion tensor. 20 healthy subjects (8 female, median age 31 years) were imaged on a clinical 3T system with STEAM-IVIM. A simulation study was performed to investigate the optimal fitting algorithms for the IVIM parameters, which was subsequently used to create pixel-wise IVIM parameter maps for the in vivo acquisitions. …”
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Design of a Wearable Exoskeleton Piano Practice Aid Based on Multi-Domain Mapping and Top-Down Process Model by Qiujian Xu, Meihui Li, Guoqiang Chen, Xiubo Ren, Dan Yang, Junrui Li, Xinran Yuan, Siqi Liu, Miaomiao Yang, Mufan Chen, Bo Wang, Peng Zhang, Huiguo Ma

“…The device excels in enhancing motion accuracy, interactivity, and comfort, filling the gap in traditional piano assistance devices in terms of multi-functionality and high adaptability, and offering new ideas for the design and promotion of intelligent assistive devices. Simulation analysis, combined with the motion trajectory of the finger’s proximal joint, calculates that 60° is the maximum bending angle for the aforementioned joint. …”
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Laminated Veneers with Stratified Feldspathic Ceramics by Henrique Tuzzolo Neto, Wagner Ferreira do Nascimento, Larissa Erly, Rodrigo Alves Ribeiro, Jorge de Sá Barbosa, Jessica Mina Zambrana, Lariça Barbosa Raimundo, Cristiane da Silva Mendes, Ivan Pereira da Silva, Alfredo Mikail Melo Mesquita, Daniela Miranda Richarte de Andrade Salgado, Claudio Costa

“…The color of the cementing agent was chosen using a glycerin-based compound which simulates the final color of the cement. After two hours of drying, two different layers of silane were applied for 60 seconds. …”
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Study on the Key Influential Factors on Water Huff-n-Puff in Ultralow-Permeability Reservoir by Xiaoyan Wang, Kun Xie, Jie Zhang, Yong Zhang, Yang Zhang, Wei Wang, Xi Yan, Fengxiang Zhao

“…This manuscript studied the key influential factors of water huff-n-puff and related improving recovery methods using physical simulation experiments to put forward a beneficial condition for water huff-n-puff, combining with the field practice. …”
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Fault tolerant & priority basis task offloading and scheduling model for IoT logistics by Asif Umer, Mushtaq Ali, Ali Daud, Lal Hussain, Amal Bukhari, Ali Imran Jehangiri

“…The model's performance is evaluated through simulations in iFogSim2. Results demonstrate reductions in energy consumption by up to 5.8 % and 10.4 %, decreases in SLA violations by up to 25.2 %, and a 16.28 % improvement in response time compared to an ACO-based model with a response time of 17.8 %. …”
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Computer-guided identification of novel inhibitors of apoptosis-signaling kinase 1 from Spondia mombim bioactive compounds against colorectal cancer by Olusola Olalekan Elekofehinti, Hannah Oluwaseun Popoola, Adedotun Olayemi Oluwatuyi, Opeyemi Iwaloye, Moses Orimoloye Akinjiyan, Oluwamodupe Cecilia, Frank Abimbola Ogundolie, Olalekan Isaac Olatunde, Oussama Abchir, Samir Chtita, Joao Batista Texeira Rocha

“…These compounds showed modest indices for ADMET parameters. Molecular dynamic simulation validated ellagic acid and (-)-catechin with greater binding stability as leading compounds. …”
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Integrated Three-Dimensional Structural and Petrophysical Modeling for Assessment of CO2 Storage Potential in Gas Reservoir by Syed Yasir Ali Shah, Jiangfeng Du, Sayed Muhammad Iqbal, Linze Du, Umair Khan, Baoyi Zhang, Jingqiang Tan

“…Three-dimensional property models were generated using sequential Gaussian simulation to represent the distribution of petrophysical properties, for example porosity, permeability, shale volume, and water saturation. …”
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Linkage Analysis between Solid-Fluid Coupling and the Strength Reduction Method for Karst Cave Water Inrush in Mines by Yanlin Zhao, Jian Liao, Qiang Liu, Yang Li, Jianchao Cheng

“…Once the rock pillar becomes unstable, Karst water bursts from confined Karst cave in a pipe flow shape, and the water irruption quantity reaches the peak value in a short time by adopting the pipe flow to simulate and then decreases slowly. The hydraulic rough flow at the initial stage changes into pipe laminar flow finally in the process of Karst water inrush, due to the constraint of Karst cave water reserve. …”
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Cost–utility and budget impact analysis of tocilizumab for the treatment of refractory systemic juvenile idiopathic arthritis in Thailand by Nitichen Kittiratchakool, Disorn Kulpokin, Chonticha Chanjam, Soamarat Vilaiyuk, Sirirat Charuvanij, Gun Phongsamart, Parichat Khaosut, Manasita Tanya, Ratanavadee Nanagara, Sira Nantapaisarn, Pattara Leelahavarong

“…Objectives This study aimed to analyse the cost–utility and budget impact of adding tocilizumab to the standard treatment for patients with refractory systemic juvenile idiopathic arthritis (sJIA) in Thailand.Design Economic evaluation using a decision-analytical model.Setting Thailand.Participants Patients with refractory sJIA who were ≥2 years old.Methods The use of tocilizumab as an add-on therapy to standard treatment was compared with standard treatment alone. A simulated health state transition model was used to estimate the lifetime costs and health outcomes from a societal perspective. …”
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Assessing gut barrier integrity and reproductive performance following pre-mating oral administration of solid-lipid-nanoparticles designed for drug delivery by Valentina Lacconi, Valentina Lacconi, Micol Massimiani, Micol Massimiani, Giulia Antonello, Paolo Gasco, Roberta Bernardini, Cristiana Ferrari, Lorenzo Ippoliti, Gina La Sala, Antonio Pietroiusti, Ivana Fenoglio, Chiara Riganti, Luisa Campagnolo

“…The in vitro model further confirmed the biocompatibility of SLNs, showing that both loaded and unloaded SLNs did not affect the integrity of the simulated intestinal epithelial barrier. In conclusion, these data suggest that administering SLNs, as a drug delivery vehicle, prior to conception does not affect either maternal health or fetal development, posing no risk to future pregnancy.…”
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Stochastic population models to identify optimal and cost‐effective harvest strategies for feral pig eradication by Peter W. Hamnett, Frédérik Saltré, Brad Page, Myall Tarran, Matt Korcz, Kate Fielder, Lindell Andrews, Corey J. A. Bradshaw

“…In all scenarios above, the minimum required harvest rate and the total cost to reduce population to ≤10% of N0 decreased with increasing harvest proportion, with lower total costs incurred over 3 years compared to 10 years. The simulations suggest that the most cost‐effective approach for most scenarios is to maximize annual harvest and complete eradication effort over the shortest periods.…”
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Deflection of screen surface and spatial deformation law of screen apertures during 1 mm elastic screening by Haishen JIANG, Ran YANG, Runyu LIU, Shijie YU, Peng GUO, Miao PAN, Long HUANG, Chenlong DUAN

“…To overcome the problems above, combining vibration testing and multi-flexible body dynamics simulation methods, the kinematic characteristics of elastic screen surface and 1 mm elastic screening test were carried out. …”
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EV Hybrid Battery With Integrated Multilevel Neutral-Point-Clamped Interfacing and Lossless Intermodule State-of-Charge Balancing by Gabriel Garcia-Rojas, Sergio Busquets-Monge, Alber Filba-Martinez, Turev Sarikurt, Salvador Alepuz, Josep Bordonau

“…Overall, the proposed approach enables a modular and scalable design of the energy storage system for a wide range of electric vehicles, from only two different standard battery modules and a standard power semiconductor device, while optimizing the battery size for any given battery power and energy specification. Simulation and experimental results are provided in the case of a three-level internal battery interfacing to verify the good performance of the proposed novel hybrid battery configuration, modulation, and control.…”
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Explainable artificial intelligence in web phishing classification on secure IoT with cloud-based cyber-physical systems by Sultan Refa Alotaibi, Hend Khalid Alkahtani, Mohammed Aljebreen, Asma Alshuhail, Muhammad Kashif Saeed, Shouki A. Ebad, Wafa Sulaiman Almukadi, Moneerah Alotaibi

“…At last, the XAIAOA-WPC method incorporates the XAI model LIME for superior perception and explainability of the black-box process for precise identification of intrusions. The simulation outcome of the XAIAOA-WPC method is examined on a benchmark database. …”
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