Prescription of Strong Opioids in Chronic Non-Cancer Pain in the Province of Valladolid (Spain) by Rodrigo Enríquez de Salamanca Gambara, Ana María Sierra Santos, Ana María Ruiz San Pedro, Federico Montero Cuadrado, Irene Muñoz León, Miguel Ángel Castro Villamor, Alicia Córdoba Romero, Ana María Del Olmo Tornero, Lucía Pérez Pérez, León Morales-Quezada

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Evaluation of Hydrocarbon Generation Using Structural and Thermal Modeling in the Thrust Belt of Kuqa Foreland Basin, NW China by Chengfu Lyu, Xixin Wang, Xuesong Lu, Qianshan Zhou, Ying Zhang, Zhaotong Sun, Liming Xiao, Xin Liu

“…A large number of overthrust faults, fault-related folds, and salt-related structures are formed on the thrust belt due to strong compression and structural deformation, causing difficulty in simulation of the basin. In this study, modeling of the thermal history of the complicated compressional structural profiles in the Kuqa foreland basin was successfully conducted based on the advanced “Block” function introduced by the IES PetroMod software and the latest geological interpretation results. …”
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Modeling Burst Error Processes in ITU-T G.hnem-Based PLC Systems: Noisy Indoor Environment Analysis Using a Generative Semi-Hidden Markov Model by Akintunde Oluremi Iyiola, Theo G. Swart, Ayokunle Damilola Familua, Thokozani Shongwe

“…A comparative analysis of reference error sequences and SHMM simulations demonstrates the model’s ability to accurately replicate NB-PLC-specific error dynamics, including error clustering and state transitions. …”
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Co-Optimization of Power Delivery Network Design for 3-D Heterogeneous Integration of RRAM-Based Compute In-Memory Accelerators by Madison Manley, James Read, Ankit Kaul, Shimeng Yu, Muhannad Bakir

“…Using our framework, we model IR-drop and simulate its impact on the accuracy of ResNet-50 and ResNet-152 when classifying images from the ImageNet 1k dataset in the presence of injected PVT noise. …”
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Effect of Massage on the TLR4 Signalling Pathway in Rats with Neuropathic Pain by Qian Wang, Jing Lin, Peng Yang, Yingye Liang, Dongming Lu, Kailong Wang, Wei Gan, Jianping Fu, Zhenbao Gan, Mingchen Ma, Pingting Wu, Fengshi He, Jun Pang, Hongliang Tang

“…The rats in the massage group underwent massage using a massage simulation machine once a day for 14 d in succession; the hind limbs of the rats in the sham massage group were gently touched with a cloth bag once a day for 14 continuous days. …”
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Protocol for a feasibility study and process evaluation of a psychosocially modelled diabetes education programme for young people with type 1 diabetes: the Youth Empowerment Skill... by Nick Sevdalis, Khalida Ismail, Tayana Soukup, Trevor Murrells, Dulmini Kariyawasam, Stephen Thomas, Judith Parsons, Angus Forbes, Rita Forde, Maria Baldellou Lopez, Marie Jones, Martha Ford-Adams, Nardos Yemane, Siobhan Pender, Alex Silverstien

“…The programme aims to facilitate a positive adaptation to life with diabetes and engagement with diabetes care through peer-based learning, immersive simulations and support from an outreach youth worker. …”
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Partially Isolated Dual Work Function Gate IGZO TFT With Obviously Reduced Leakage Current for 3D DRAMs by Yunjiao Bao, Gangping Yan, Lei Cao, Chuqiao Niu, Qingkun Li, Guanqiao Sang, Lianlian Li, Yanzhao Wei, Xuexiang Zhang, Jie Luo, Yanyu Yang, Gaobo Xu, Huaxiang Yin

“…The relevant operation mechanism is carefully demonstrated and verified by the simulation of the electric field and potential barrier results by technical computer-aided design (TCAD). …”
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Ferula communis leaf extract: antioxidant capacity, UHPLC–MS/MS analysis, and in vivo and in silico toxicity investigations by Imad Ed-Dahmani, Mohamed El Fadili, Ghizlane Nouioura, Fahd Kandsi, Yassine El Atki, Hatem A. Abuelizz, Raffaele Conte, Fatima Zahra Lafdil, Abdeslam Taleb, Abdelfattah Abdellaoui, Mustapha Taleb

“…In addition, a detailed molecular dynamics simulation was carried out to examine the thermodynamic stability of the produced intermolecular interactions. …”
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Danlian-Tongmai formula improves diabetic vascular calcification by regulating CCN3/NOTCH signal axis to inhibit inflammatory reaction by Wenting Wang, Yiwen Li, Mengmeng Zhu, Qian Xu, Jing Cui, Yanfei Liu, Yanfei Liu, Yue Liu

“…Molecular docking and molecular dynamics simulation demonstrated strong binding interactions between DLTM metabolites and key molecules within the CCN3/NOTCH pathway, including NOTCH1, DLL1, DLL4, hes1, and hey1. …”
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An improved statistical bias correction method for Global Climate Model (GCM) precipitation projection: A case study on the CMCC-CM2-SR5 model projection in China’s Huaihe River Ba... by Yuning Luo, Ke Zhang, Wen Wang, Xinyu Chen, Jin Feng, Haijun Wang, Wei Liu, Cheng Guo, Cuiying Chen, Xiaozhong Wang

“…The LS-EDCDF method incorporates recurrence periods and least squares with the determination of transfer functions relating observation to model simulation. We applied this and three other methods—EquiDistant Cumulative Distribution Function matching method (EDCDF), combined Linear Scaling and Cumulative Distribution Function matching method (LS-CDF) and Quantile-quantile mapping method (QUANT)—to correct biases in the CMCC-CM2-SR5 model. …”
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Enhanced radiation shielding via incorporating europium oxide in 316L stainless steel: Synthesis, physical, microstructural, shielding, and mechanical properties by H.O. Tekin, Nihal Yayla, M.Gökhan Albayrak, Ömer Güler, Duygu Sen Baykal, Hessa Alkarrani, Ghada ALMisned

“…Transmission factors (TFs) were evaluated using PHITS simulations for photon energies of 0.662 MeV, 1.1732 MeV, and 1.3325 MeV. …”
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City information models for optimal EV charging and energy-resilient renaissance by Zhaohui Dan, Aoye Song, Yuyu Zheng, Xinyue Zhang, Yuekuan Zhou

“…It enhances urban renewable energy penetration by up to 50.1%, reduces road traffic carbon emissions by up to 46.6%, and decreases power outage hours and simulation time. This study offers a city-scale IoE model for optimal infrastructure planning and climate-adaptive energy-resilient renascence. …”
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Designing a multi-epitope vaccine candidate against human rhinovirus C utilizing immunoinformatics approach by Tajul Islam Mamun, Tajul Islam Mamun, Md. Ahad Ali, Md. Nazmul Hosen, Jillur Rahman, Md. Anwarul Islam, Md. Golam Akib, Kamruz Zaman, Md. Masudur Rahman, Md. Masudur Rahman, Ferdaus Mohd Altaf Hossain, Ferdaus Mohd Altaf Hossain, Samir Ibenmoussa, Mohammed Bourhia, Turki M. Dawoud

“…Molecular dynamics and simulation studies revealed a stable Vaccine-TLR8 complex, with a binding energy of -296.15 and consistent RMSD values. …”
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Comparison of Tropospheric Horizontal Gradients Modeling Methods in LEO Constellation Augmented GNSS Precise Point Positioning by Xinyu Zhang, Wenwu Ding, Xiaochuan Qu, Hongjin Xu, Xuanzhao Tan, Yunbin Yuan

“…In this research, we compare the performances of several troposphere gradient models in describing the asymmetrical troposphere delays. Using simulation data during the stable and severe periods, we find that the high-order horizontal gradient models exhibit higher accuracy in the experiments. …”
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Insights from a codesigned dynamic modelling study of child and adolescent obesity in Australia by Alison Hayes, Rebecca Wyse, Anna Lene Seidler, Kylie E Hunter, Rebecca K Golley, Louise A Baur, Anthony D Okely, Kenny Lawson, Jo-An Occhipinti, Louise Freebairn, Simon Keith Chiu, Joseph Carrello, L Kurt Kreuger

“…Intervention-based scenarios were simulated to examine how changes in environmental factors and health-related behaviours may affect the prevalence of obesity. …”
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Road Transport and Urban Mobility Greenhouse Gas Emissions Factor for Air Pollution Modeling in Burkina Faso by Issaka Abdou Razakou Kiribou, Tiga Neya, Bernard Nana, Kehinde Ogunjobi, Tizane Daho, Y․ Woro Gounkaou, Faith Mawia Muema, Dejene W. Sintayehu

“…In the business-as-usual condition, an average annual CO2 production of 213.71 thousand tons is simulated from 2019 to 2040. A total emission of 4 486 559.34 tons (4486.64 GgCO2) by 2040 is expected with a share of 62 % for gasoline and 38 % for diesel. …”
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A clean energy Korea by 2035: Transitioning to 80% carbon-free electricity generation by Won Young Park, Yong Hyun Song, Nikit Abhyankar, Hee Seung Moon, Umed Paliwal, Eunsung Kim, Nina Khanna, Sanghyun Hong, James Hyungkwan Kim, Kenji Shiraishi, Jiang Lin, Seung Wan Kim, Amol Phadke

“…Declined clean energy costs can reduce electricity supply costs by 23%–40% compared with 2022. Hourly dispatch simulations indicate that South Korea’s grid can integrate high levels of variable renewables without coal generation or new natural gas power plants. …”
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Emergency Airway Management: A Systematic Review on the Effectiveness of Cognitive Aids in Improving Outcomes and Provider Performance by Raisa Chowdhury, Ostap Orishchak, Marco A. Mascarella, Bshair Aldriweesh, Mohammed K. Alnoury, Guillaume Bousquet-Dion, Jeffrey Yeung, Lily Ha-Nam P. Nguyen

“…The Vortex method and visual cognitive aids demonstrated particular effectiveness in simulated scenarios. <b>Conclusions:</b> Cognitive aids significantly enhance emergency airway management skills, improving performance, reducing errors, and increasing provider confidence. …”
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The accurate determination of Perfluorooctane sulfonic acid (PFOS) removal efficiency by integrated-sonochemical system by Debabrata Panda, Maxime Cochennec, Stéfan Colombano, Benjamin Laulier, Pascal Tierce, Alexandre Baudouard, Sebastian Bristeau, Anne Togola, Julie Lions, Nicolas Devau, Eric D. van Hullebusch

“…In this work, we have conducted the sonochemical treatment of PFOS simulated water under high (500 kHz) and low (22 kHz) frequencies while monitoring the operational parameters via an integrated sonochemical system. …”
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Air temperature and precipitation constraining the modelled wetland methane emissions in a boreal region in northern Europe by T. Aalto, A. Tsuruta, J. Mäkelä, J. Müller, J. Müller, M. Tenkanen, E. Burke, S. Chadburn, Y. Gao, V. Mannisenaho, T. Kleinen, H. Lee, H. Lee, A. Leppänen, T. Markkanen, S. Materia, P. A. Miller, D. Peano, O. Peltola, B. Poulter, M. Raivonen, M. Saunois, D. Wårlind, S. Zaehle

“…Furthermore, it is important to use process-based descriptions for both mineral and peat soil fluxes to simulate the flux responses to climate drivers.</p>…”
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