Selective suppression of influenza A/H5N1 virus replication <i>in vitro</i> using nanocomplexes consisting of siRNA and aminopropylsilanol nanoparticles by Marina N. Repkova, Asya S. Levina, Oleg Yu. Mazurkov, Elena V. Makarevich, Ekaterina I. Filippova, Natalya A. Mazurkova, Valentina F. Zarytova

“…The aim of the study is to create nanocomplexes consisting of aminopropylsilanol nanoparticles and short interfering RNA (siRNA) to study their effect on target nucleic acids by the example of inhibition of influenza A virus replication in vitro. …”
Get full text

Weight cycling exacerbates glucose intolerance and hepatic triglyceride storage in mice with a history of chronic high fat diet exposure by Miriam Bernecker, Anna Lin, Annette Feuchtinger, Anna Molenaar, Sonja C. Schriever, Paul T. Pfluger

“…To date, our understanding of such long-term obesity and weight cycling effects is still limited and often based on only short-term murine weight gain and loss studies. This study aimed to investigate the long-term impacts of weight cycling on glycemic control and metabolic health, focusing on adipose tissue, liver, and hypothalamus. …”
Get full text

Isolation, screening and in-vitro characterization of plant growth-promoting Bradyrhizobium isolates from the nodules of Bambara groundnut (Vigna subterranean) for potential use as... by Osman Abdulai Seidu, Stephen Mwangi Githiri, John Mwibanda Wesonga, Victoria Wambui Ngumi

“…Although the crop can fix nitrogen, its yields frequently fall short of their maximum potential which can be attributed to association with ineffective rhizobia strains. …”
Get full text

Preliminary Evaluation of Some Engineering Geological Properties of Soils in the New Yenagoa Town, Bayelsa State, Central Niger Delta by PO Youdeowei, HO Nwankwoala

“…The subsurface investigation was undertaken by drilling of ten near the shore drill holes using rotary type drill machine. …”
Get full text

Managing Post COVID-19 Patient with Breathlessness by Yen Shen Wong, Muhammad Amin Ibrahim, Mohd Arif Mohd Zim, Mohd Fauzi Abdul Rani

“…Unfortunately, he was re-admitted after 2 weeks with shortness of breath and fever for 3 days. Blood results revealed leucocytosis with raised C-reactive protein. …”
Get full text

Virtual delivery of Go4Life® resources: A pilot study enhancing physical activity in older adults through pre- and post-intervention evaluation by Nazia Naz S. Khan, MD, MS, Syed S. Raza, BS, Nikhil Regmi, MD, Ling Wang, Ph.D

“…Secondary outcomes included weekly changes in activity level developed from the NIA's Track your activity sheets and RAND 36-Item Short Form Survey Instrument (SF-36) questionnaires. …”
Get full text

Acute Effects of Drop Jumps on Lower Limb Stiffness and Mechanical and Kinematic Parameters During High-Speed Treadmill Running by Panagiotis Pappas, Ioannis Stavridis, Giorgos Paradisis

“…The findings suggest that a plyometric stimulus of low volume and a short recovery period prior to high-speed treadmill running may be beneficial to acutely improve running mechanical and kinematic parameters without affecting lower limb stiffness.…”
Get full text

Factors Associated with the Severity of Stress Urinary Incontinence in Elderly Women by Suting Li, Zhi Wang, Lian Yang, Shaoying Liu, Lili Jing, Li Hong

“…Data collection encompassed demographic information, clinical features (including obstetric history, chronic diseases, Urogenital Distress Inventory-6 (UDI-6), and International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) scores), as well as physical examinations (including assessments of pelvic floor muscle strength, pelvic organ prolapse quantification (POP-Q) system, and pelvic floor ultrasound imaging). …”
Get full text

Influence of kinesiophobia on activity, function, and anxiety levels in patients with rheumatoid arthritis by Shang Xueying, You Yanli, Xu Wei, Zhang Lingling, Li Lili

“…Participants completed the Tampa Scale of Kinesiophobia (TSK), the Signals of Functional Impairment Scale (SOFI), the International Physical Activity Scale—Short Form (IPAQ-SF), and the Pain Anxiety Symptoms Scale-20 (PASS-20). …”
Get full text

MLHI-Net: multi-level hybrid lightweight water body segmentation network for urban shoreline detection by Jianhua Ye, Pan Li, Yunda Zhang, Ze Guo, Shoujin Zeng, Youji Zhan

“…The majority of extant methods are unable to adapt to the discrimination of high similarity features between the shore and reflections in complex and diverse environments. …”
Get full text

Characterization of the fungal genus Sphaerellopsis associated with rust fungi: species diversity, host-specificity, biogeography, and in-vitro mycoparasitic events of S. macroconi... by Paula Andrea Gómez-Zapata, Jorge Ronny Díaz-Valderrama, Samira Fatemi, Cristhian Orlando Ruiz-Castro, M. Catherine Aime

“…Finally, we confirm the mycoparasitic strategy of S. macroconidialis through in-vitro interaction tests with the urediniospores of Puccinia polysora. Shortly after germination, hyphae of S. macroconidialis began growing along the germ tubes of P. polysora and coiling around them. …”
Get full text

Psychometric Testing of the CHAMPS Questionnaire in French Canadians with COPD by Susanne Mak, Jean Bourbeau, Nancy E. Mayo, Sharon Wood-Dauphinee, Judith E. Soicher

“…Validity was assessed in 56 English-speaking and 74 French-speaking participants, who completed the CHAMPS, Short Form- (SF-) 36, and St. George’s Respiratory Questionnaire (SGRQ) at a single visit. …”
Get full text

A method to estimate the water storage of on-farm reservoirs by detecting slope gradients based on multi-spectral drone data by Yixuan Wang, Nana Yan, Weiwei Zhu, Zonghan Ma, Bingfang Wu

“…Previous studies have primarily relied on the area-storage model to estimate reservoir water storage using meter-level remotely sensed data, which often falls short of accurately capturing the water storage dynamics of OFRs, especially in small OFRs with steep slopes. …”
Get full text

HDNLS: Hybrid Deep-Learning and Non-Linear Least Squares-Based Method for Fast Multi-Component T1ρ Mapping in the Knee Joint by Dilbag Singh, Ravinder R. Regatte, Marcelo V. W. Zibetti

“…Due to the inverse-problem nature of the parameter mapping, certain parameters in a specific model may be more sensitive to noise, such as the short component in the BE model. To address this, the number of NLS iterations in HDNLS can act as a regularization, stabilizing the estimation to obtain meaningful solutions. …”
Get full text

Outcomes of Pediatric Patients with Crohn’s Disease Received Infliximab or Exclusive Enteral Nutrition during Induction Remission by Yao Lv, Yue Lou, Gan Yang, Youyou Luo, Jingan Lou, Qi Cheng, Jindan Yu, Youhong Fang, Hong Zhao, Kerong Peng, Jie Chen

“…Our study suggested that EEN treatment is similar with IFX therapy in short-term outcomes, and EEN+6-MP/MTX treatment is comparable with IFX+IFX therapy in long-term outcomes.…”
Get full text

Digital business strategy of enterprise and its components by Liubov Lipych

“…It is proven that the digital business strategy describes the overall vision of the company in the context of digitalization, including strategic measures to achieve it. It defines specific, short-, medium- and long-term digitalization goals and initiatives in the context of products, services and value creation, as well as the company's organization and culture. …”
Get full text

Ocular Findings in COVID-19 Patients: A Review of Direct Manifestations and Indirect Effects on the Eye by Federica Bertoli, Daniele Veritti, Carla Danese, Francesco Samassa, Valentina Sarao, Nicolò Rassu, Tommaso Gambato, Paolo Lanzetta

“…However, the risk of retinal toxicity with short-term high-dose use of antimalarials is still unknown. …”
Get full text

Effect of anastomotic reinforcement with barded suture on anastomotic leakage prevention following laparoscopic low anterior resection for rectal cancer: a retrospective single-cen... by Xinyu Qi, Kai Xu, Maoxing Liu, Fei Tan, Pin Gao, Chuanyong Zhou, Zhendan Yao, Nan Zhang, Hong Yang, Chenghai Zhang, Jiadi Xing, Ming Cui, Xiangqian Su

“…No statistically significant differences were found in 36-item short-Form (SF-36) when evaluating the quality of patient’s life between the two groups. …”
Get full text

A Hybrid Artificial Neural Network and Particle Swarm Optimization algorithm for Detecting COVID-19 Patients by Alla Ahmad Hassan, Tarik A Rashid

“…Diseased people experience severe symptoms in more severe cases. such as shortness of breath, which can lead to respiratory failure and death. …”
Get full text

Development and comprehensive greenness assessment of HPLC method for quality control of β-sitosterol in pharmaceutical ointments with trio-color coded evaluation by Haya I. Aljohar, Abdullah M. Al-Hossaini, Seham A. Alzammay, Samiah Alhabardi, Hadir M. Maher, Aya R. Ahmed

“…Additionally, the separation was achieved in a remarkably short analysis time of just 2.1 min, which not only enhanced throughput but also significantly minimized waste and solvent consumption, thereby making it a more sustainable and effective alternative for β-sitosterol extraction. …”
Get full text