High-throughput tracking enables systematic phenotyping and drug repurposing in C. elegans disease models by Thomas J O'Brien, Ida L Barlow, Luigi Feriani, André EX Brown

“…Our results show that a single assay to measure multiple phenotypes can be applied systematically to diverse Mendelian disease models. The relatively short time and low cost associated with creating and phenotyping multiple strains suggest that high-throughput worm tracking could provide a scalable approach to drug repurposing commensurate with the number of Mendelian diseases.…”
Get full text

Case report: identification of novel variant in SLC26A2 gene and preimplantation genetic testing for monogenic disorders in preventing diastrophic dysplasia by Ziravard N. Tonyan, Yulia A. Nasykhova, Maria M. Danilova, Elena S. Shabanova, Olesya N. Bespalova, Igor Y. Kogan, Andrey S. Glotov

“…A testing system was developed to analyze pathogenic variants in the SLC26A2 gene, alongside with indirect markers such as short tandem repeats and single nucleotide polymorphisms. …”
Get full text

Donor Heart Utilization following Cardiopulmonary Arrest and Resuscitation: Influence of Donor Characteristics and Wait Times in Transplant Regions by Mohammed Quader, Luke Wolfe, Gundars Katlaps, Vigneshwar Kasirajan

“…Factors favoring heart procurement include younger age, male gender, short CPR duration, and traumatic head injury. Heart procurement varied by region but not by transplant volumes or wait times.…”
Get full text

Developing an Index to Measure the Value of Health Care Provided to Stroke Patients by Halil Şengül, Sabahattin Aydın, Emrah Önder, Arzu Bulut

“…Questions with a content validity index exceeding 0.80, along with the World Health Organization responsiveness questionnaire and the Patient-Reported Outcomes Measurement Information System Global-10 short form, were subjected to pairwise comparison by two neurologists, two interventional radiologists, and two public health physicians using the analytic hierarchy process (AHP) method. …”
Get full text

Pseudomyxoma Peritonei Originating from Transverse Colon Mucinous Adenocarcinoma: A Case Report and Literature Review by Yingbo Gong, Xin Wang, Zhi Zhu

“…It was diagnosed during resective surgery, involved ovarian metastasis, and survival was short. We did an extensive literature review in order to describe the clinical characteristics, histopathological findings, genetic profile, and potential treatments of PMP caused by nonappendiceal mucinous adenocarcinoma.…”
Get full text

Sea Defence Project and a UNESCO World Heritage Monument in Coastal Ghana by Justice Mensah

“…These have increased the resilience and protective capacity of the monument and enhanced the aesthetic value and sanitation at the site, thereby shoring up the integrity and authenticity of the site and culminating in its enhanced sustainability and OUV. …”
Get full text

Fatigue State Evaluation of Urban Railway Transit Drivers Using Psychological, Biological, and Physical Response Signals by Hao Wu, Yubo Jiao, Chaozhe Jiang, Tong Wang, Jiangbo Yu

“…With feature fusion, even short-term time windows can encapsulate sufficient information for effective fatigue detection. …”
Get full text

Alteration of Thyroid-Related Hormones within Normal Ranges and Early Functional Outcomes in Patients with Acute Ischemic Stroke by Xiao-yan Xu, Wen-yu Li, Xing-yue Hu

“…In sum, lower total T3 concentrations that were within the normal ranges were independently associated with poor short-term outcomes.…”
Get full text

A Rare Cause of Pain in a Patient Following Roux-en-Y Choledochojejunostomy by Kristiana Sather, Matthew Wheelwright, Guru Trikudanathan, Gregory Beilman

“…He underwent endoscopic retrograde cholangiopancreatography (ERCP) with the removal of large amounts of debris with initial resolution of his pain, but the pain recurred after several months and after two further ERCPs with only short-term resolution of pain, he eventually underwent an open distal CBD excision and the pain has since resolved. …”
Get full text

Development of Postural Control in Healthy Children: A Functional Approach by Christine Assaiante, Sophie Mallau, Sébastien Viel, Marianne Jover, Christina Schmitz

“…The studies dealing with adaptation of postural strategies aimed at testing short and long-term adaptation capacity of the CNS during imposed transient external biomechanical constraints in healthy children, and during chronic internal constraints in children with skeletal pathologies. …”
Get full text

Analysis of the Learning Curve of Surgeons without Previous Experience in Laparoscopy to Perform Robot-Assisted Radical Prostatectomy by Felipe Monnerat Lott, Deborah Siqueira, Hermano Argolo, Bernardo Lindberg Nóbrega, Franz Santos Campos, Luciano Alves Favorito

“…Robot-assisted radical prostatectomy does not require previous experience in laparoscopic radical prostatectomy, but the learning curve is not short to achieve the plateau.…”
Get full text

Sustainable organisation management system: properties and factors by A. A. Dolgaya

“…In particular, the most striking indicator of the sustainability of the management system is the priority of long-term goals over short-term ones in the choice of production technologies in the company’s development process. …”
Get full text

Hydrodynamics of flow through living shoreline structure by Tanhaseng Kanyarat, Kositgittiwong Duangrudee, Ekkawatpanit Chaiwat, Kompor Wongnarin, Petpongpan Chanchai

“…A series of 40 controlled numerical tests was conducted with seadomes arranged in five shore-parallel rows near the shoreline. The analysis reveals that a relative structure height (D/h) exceeding 1.0, coupled with a relative wavelength (L/Be) between 0.5 and 1.0, leads to wave amplitude reductions of over 90%. …”
Get full text

Investigation the physical activity level of academics: Çanakkale sample by Ozhan Bavlı, Songul Cınar

“…International physical activity questionary (IPAQ) short form used tocollect data. SSPS 17,0 used to analysis. …”
Get full text

The first cases of collagenous sprue successfully treated with thioguanine by Chris J J Mulder, Gerd Bouma, Tom van Gils, Tine van de Donk, Foke van Delft, E Andra Neefjes-Borst

“…The thickened membrane persisted in the last patient, probably because of the short time of follow-up.Conclusions CS should be separated from coeliac disease. …”
Get full text

Protective Effect of Daikenchuto on Dextran Sulfate Sodium-Induced Colitis in Mice by Takaharu Matsunaga, Shinichi Hashimoto, Naoki Yamamoto, Ryo Kawasato, Tomohiro Shirasawa, Atsushi Goto, Koichi Fujisawa, Taro Takami, Takeshi Okamoto, Jun Nishikawa, Isao Sakaida

“…First, we assessed the short-term effects of DKT using two groups: 5% DSS group and 5% DSS with DKT group. …”
Get full text

The potential of digital health interventions to address health system challenges in Southeast Asia: A scoping review by Vanita Singh, Rosemol Johnson K, Anil G. Jacob, Oommen John

“…Conclusion Most of the existing DHIs in SEA region address challenges related to availability of services and lack of information, while they fall short in addressing challenges related to quality of services, efficiency, and accountability. …”
Get full text

Polyurethanes as Biomaterials in Medicine: Advanced Applications, Infection Challenges, and Innovative Surface Modification Methods by Drożdż Kamil, Gołda-Cępa Monika, Brzychczy-Włoch Monika

“…PUs are employed in a diverse array of medical devices, including non-implantable applications such as wound dressings, catheters, and infusion sets; short-term implants like bone stabilizers and tracheostomy tubes; and long-term implants such as tissue regeneration scaffolds, artificial blood vessels, and heart valves. …”
Get full text

Evaluating the Influence of Drying Shrinkage on Cracking Resistance of Massive Self-Compacting Concrete with Blast Furnace Slag Using Finite Element Method by Benson Kipkemboi, Shingo Miyazawa

“…This conclusion is from short-term research work of up to 3 months after casting. …”
Get full text

Computer-Based Clinical Examination (CCE) in Surgery: Would It Complement or Replace the OSCE in the Post-COVID-19 Era? by Gamal E H A El Shallaly, Mudather M Bafadni, Hozifa M A Abdelmaged, Maysa H A Hamza

“…Each consisted of a clinical scenario accompanied by a photograph (of a patient or investigation) or short video followed by multiple choice questions (MCQs). …”
Get full text