Latest Approved Therapies for Metastatic Melanoma: What Comes Next? by Farid Menaa

“…The recent oncogene-directed therapeutic, vemurafenib, usually produces high level of tumor shrinkage and survival benefits in many patients with B-RA mutant melanomas, although the fast and high degrees of responses are likely short-lived. Conversely, the newly-approved immunotherapeutic, ipilimumab, produces durable responses in patients presenting CTLA-4 T-cell surface protein. …”
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A Client-Centric Evaluation System to Evaluate Guest’s Satisfaction on Airbnb Using Machine Learning and NLP by Mohamed Chiny, Omar Bencharef, Moulay Youssef Hadi, Younes Chihab

“…Understanding the determinants of satisfaction in P2P hosting is crucial, especially with the emergence of platforms such as Airbnb, which has become the largest platform for short-term rental accommodation. Although many studies have been carried out in this direction, there are still gaps to be filled, particularly with regard to the apprehension of customers taking into account their category. …”
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NIGERIAN LOCAL GOVERNMENT ADMINISTRATION: A COMPARATIVE ANALYSIS OF THE THIRD AND FOURTH REPUBLICS by Towoju Adedoyin John, Mohammed Idris Danjuma, Ibrahim O Salawu

“…The major findings were that each reform measure was necessitated by the short-comings inherent in the preceding system; some of the reforms were far reaching and had positive impacts, while others were cosmetic in nature and mainly for political expediency. …”
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Bidirectional effects of neutrophils on Streptococcus oralis biofilms in vitro by Basmah M. Almaarik, Rizwan Ali, Paul R. Cooper, Michael R. Milward, Josefine Hirschfeld

“…Neutrophils produced elevated total and intracellular ROS, however, no NETs in response to biofilms.Conclusion Neutrophils in vitro are not excessively activated by S. oralis biofilms but are able to reduce biofilm quantity in the short-term, possibly through interfering with eDNA.…”
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Nuclear N-WASP Induces Actin Polymerization in the Nucleus with Cortactin as an Essential Factor by Xin Jiang, Purusottam Mohapatra, Maria Rossing, Wenqian Zheng, Olga Zbodakova, Jayashree Vijay Thatte, Claus Storgaard Sørensen, Thu Han Le Phan, Cord Brakebusch

“…N-WASP-dependent actin polymerization promoted the maturation of RNA Pol II clusters, with the short truncation mutant R128* unexpectedly showing the strongest effect. …”
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Demographic Trends and Evolving Housing Needs in Latvia: Implications for Social Housing Policy by Sanchaniya Rashmi Jaymin, Černeckienė Jurgita, Patel Shruti Jitendrakumar, Kundziņa Antra

“…Based on these findings, the article proposes policy recommendations to address Latvia’s evolving housing needs. These include short-term adjustments to current policies, long-term strategic planning for housing development, and innovative financing mechanisms for social housing. …”
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Preservation of Aquatic Environmental DNA Using Cationic Detergents by Viresh Thamke, Yared H. Bezabhe, Jana Jass, Per‐Erik Olsson

“…In this study, we assessed the effect of short‐ and long‐term water storage using three different cationic surfactants on the half‐life of zebrafish (Danio rerio) mitochondrial DNA (mtDNA) in mesocosm water. …”
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Validation of perceived invalidation of emotion scale (PIES) in Iranian populations by Mehdi Rezaei, Zahra Paripishbar, Samaneh Khazaei

“…Methods A total of 2250 participants (clinical sample = 177, student samples = 1762, general population = 311) completed the following questionnaires: Perceived Invalidation of Emotion Scale (PIES), Childhood Trauma Questionnaire-Short form (CTQ-SF), Depression, Anxiety and Stress (DASS-2), and the Difficulties in Emotion Regulation Scale-16 (DERS-16). …”
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Lithium-Ion Battery State of Health Degradation Prediction Using Deep Learning Approaches by Talal Alharbi, Muhammad Umair, Abdulelah Alharbi

“…Three deep learning architectures 1D Convolutional Neural Networks (CNN), CNN plus Long Short-Term Memory (LSTM), and CNN plus Gated Recurrent Units (GRU) are used in the centralized approach. …”
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Generating a Full Cycle of Alternative Current Using a Triboelectric Nanogenerator for Energy Harvesting by Aso Ali Abdalmohammed Shateri, Fengling Zhuo, Nazifi Sani Shuaibu, Rui Wan, Liangquan Xu, Dinku Hazarika, Bikash Gyawali, Xiaozhi Wang

“…It consistently delivers robust performance with an open-circuit voltage of 544 V, a short-circuit current of 61.16 µA, and a maximum power output of 33.27 mW. …”
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Computer-Aided Rapid Establishment of Fingerprint of Xiaojin Capsule by HPLC by Hui Jiang, Yuansheng Xiao, Xingya Xue, Hongli Jin, Yang Xiang, Yanfang Liu, Gaowa Jin

“…Whereas, it is a great challenge to establish the fingerprint chromatogram which can fully reflect every single herb material in a short time. In this study, we used Xiaojin capsule (XJC) as a case and developed a rapid fingerprint method based on increasing the column temperature and flow rate simultaneously combined with computer-aided. …”
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Enteropathogenic Bacterial and Intestinal Parasitic Infections among Asymptomatic Food Handlers in Rangsit University Canteens, Central Thailand by Sirima Kitvatanachai, Bajaree Jantrapanukorn, Utsanee Supcharoengoon, Chalirmporn Atasilp

“…Approximately 80% of food handlers demonstrated good hygiene practices, including regular hand washing after visiting the toilet, regular hand washing when preparing food, using soap when washing hands, wearing uniforms/gowns, practicing correct hand washing techniques, and having short fingernails. However, the results showed a lack of personal hygiene training and routine medical care (>50% of samples). …”
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Cognitive Load in eCommerce Applications—Measurement and Effects on User Satisfaction by Peter Schmutz, Silvia Heinz, Yolanda Métrailler, Klaus Opwis

“…Guidelines for designing usable interfaces recommend reducing short term memory load. Cognitive load, that is, working memory demands during problem solving, reasoning, or thinking, may affect users' general satisfaction and performance when completing complex tasks. …”
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Clinical case. Successful endoscopic treatment of an epiphrenic diverticulum of the esophagus using diverticular peroral endoscopic myotomy (D-POEM) by O Kryvoruk

“…This technique is characterized by minimal trauma to the esophageal mucosa, high efficacy, and a short rehabilitation period due to the creation of a submucosal tunnel with myotomy of the circular muscle layer directly under the mucosa, followed by the application of endoscopic clips to the mucosotomy site. …”
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Time-Dependent Reliability Analysis of RC Deep Beams considering Linear/Nonlinear Creep and Shrinkage Using ANFIS Network and MCS by Seyed Bahram Beheshti Aval, Mohsen Ghabdian

“…The software was initially examined using two experimental results for short/long-term behavior of shallow and deep concrete beams. …”
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Milling degree affects the fermentation properties of rice: perspectives from the composition of nutrients and gut microbiota via in vitro fermentation by Yu Zhang, Fan Li, Shutong Pan, Bing Bai, Kai Huang, Sen Li, Hongwei Cao, Tian Xie, Jian Xie, Xiao Guan

“…All the sample groups reduced the pH and produced short-chain fatty acids (SCFAs) and branched-chain fatty acids. …”
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Fecal Microbiota Transplantation Improves the Quality of Life in Patients with Inflammatory Bowel Disease by Yao Wei, Weiming Zhu, Jianfeng Gong, Dong Guo, Lili Gu, Ning Li, Jieshou Li

“…Patients refused to take FMT as treatment repeatedly in a short time. Conlusions. Fecal microbiota transplantation improves quality of life significantly in patients with inflammatory bowel disease.…”
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Copula-Driven Learning Techniques for Physical Layer Authentication Using Multimodal Data by Sahana Srikanth, Sanjeev Gurugopinath, Sami Muhaidat

“…For the classification task, we consider some of the well-known learning algorithms including long short-term memory (LSTM), random forest, K-nearest neighbor, support vector machine and bagging tree techniques. …”
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Performance of Dye-Sensitized Solar Cells with (PVDF-HFP)-KI-EC-PC Electrolyte and Different Dye Materials by M. M. Noor, M. H. Buraidah, S. N. F. Yusuf, M. A. Careem, S. R. Majid, A. K. Arof

“…The DSSC with Ruthenizer 535 (N3) dye exhibits the best performance with a short-circuit current density of 8.16 mA cm−2, open-circuit voltage of 0.76 V, fill factor of 0.35, and photoconversion efficiency of 2.2%.…”
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Monitoring Therapeutical Intervention with Ezetimibe Using Targeted Near-Infrared Fluorescence Imaging in Experimental Atherosclerosis by Kristof Graf, Thore Dietrich, Michael Tachezy, Frank-Detlef Scholle, Kai Licha, Philipp Stawowy, Michael Grafe, Peter Hauff, Eckart Fleck

“…There was a significant reduction in plaque size in brachiocephalic arteries in 8-month-old mice treated with EZE compared with mice during short-term treatment ( p < .05), indicating EZE plaque regression. …”
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