Optimising the secondary use of primary care prescribing data to improve quality of care: a qualitative analysis by Robert A Verheij, Niek Klazinga, Erica Barbazza, Lotte Ramerman, Dionne Kringos

“…Five main themes were identified as areas for optimising data use: (1) measuring what matters, (2) increasing data linkages, (3) improving data quality, (4) facilitating data sharing and (5) optimising fit for use analysis.Conclusions To make primary care prescribing data useful for improving quality, consolidated patient-specific data on the indication for a prescription and dispensed medicine, over time, is needed. …”
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Exploring sentiment analysis in handwritten and E-text documents using advanced machine learning techniques: a novel approach by Rayees Ahamad, Kamta Nath Mishra

“…However, it has some drawbacks like accessing and storing physical documents efficiently, searching through them, and sharing them efficiently. Handwriting-to-text recognition classifies an individual’s handwriting and converts it into digital form. …”
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Rosiglitazone, a Ligand to PPARγ, Improves Blood Pressure and Vascular Function through Renin-Angiotensin System Regulation by María Sánchez-Aguilar, Luz Ibarra-Lara, Leonardo Del Valle-Mondragón, María Esther Rubio-Ruiz, Alicia G. Aguilar-Navarro, Absalom Zamorano-Carrillo, Margarita del Carmen Ramírez-Ortega, Gustavo Pastelín-Hernández, Alicia Sánchez-Mendoza

“…Additionally, an in silico analysis revealed that 5′UTR regions of RAS and PPARγ share motifs with a transcriptional regulatory role. …”
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Simulation of Flow Around a Finite Rectangular Prism: Influence of Mesh, Model, and Subgrid Length Scale by Xutong Zhang, Maxime Savoie, Mark K. Quinn, Ben Parslew, Alistair Revell

“…Ten turbulence modelling and simulation approaches, including both ‘scale-modelling’ Reynolds-Averaged Navier–Stokes (RANS) models and ‘scale-resolving’ Delayed Detached Eddy Simulation (DDES), were tested across six different mesh resolutions. A case with sharp corners allows the location of the flow separation to be fixed, which facilitates a focus on the separated flow region and, in this instance, the three-dimensional interaction of three such regions. …”
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Experiences Using Media Health Claims to Teach Evidence-Based Practice to Healthcare Students: A Mixed Methods Study [version 3; peer review: 2 approved, 2 approved with reservatio... by Astrid Dahlgren, Marianne Molin, Jürgen Kasper, Lisa Garnweidner-Holme, Hilde Tinderholt Myrhaug, Ida-Kristin Orjasaeter Elvsaas

“…In response to the open-ended questions within the survey, 109 (80.1%) of the respondents shared positive experiences about the course, while 98 (72%) suggested improvements. …”
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Regional modeling of surface solar radiation, aerosol, and cloud cover spatial variability and projections over northern France and Benelux by G. Chesnoiu, I. Chiapello, N. Ferlay, P. Nabat, M. Mallet, V. Riffault

“…Additional ALADIN climate simulations for 2050 and 2100 under Coupled Model Intercomparison Project phase 6 (CMIP6) Shared Socioeconomic Pathway (SSP) 1-1.9 predict a significant reduction in aerosol loads compared to 2005–2014, especially over Benelux, associated with future increases in clear-sky SSR but geographically limited all-sky SSR evolution. …”
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Integrated Management of Cardiovascular–Renal–Hepatic–Metabolic Syndrome: Expanding Roles of SGLT2is, GLP-1RAs, and GIP/GLP-1RAs by Nikolaos Theodorakis, Maria Nikolaou

“…Cardiovascular–Kidney–Metabolic syndrome, introduced by the American Heart Association in 2023, represents a complex and interconnected spectrum of diseases driven by shared pathophysiological mechanisms. However, this framework notably excludes the liver—an organ fundamental to metabolic regulation. …”
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How does playfulness (re)frame the world? Evidence for selective cognitive and behavioral redirecting in times of adversity by Xiangyou Shen, Zoe Crawley

“…Sequential analyses including MANOVA, ANOVA, and ANCOVA were performed to examine overall, univariate, and adjusted group differences, respectively, validated by sensitivity analysis across three group categorization methods.ResultsThree sets of contrasting findings evidenced selective playful (re)framing effects, wherein more playful individuals (1) shared similar perceptions of current risk and protective factors while adopting a more optimistic future outlook, (2) perceived similar levels of vulnerability and isolation but engaged in significantly higher levels of resilient coping and adaptive leisure, and (3) participated in similar categories and frequencies of leisure activities but with higher experiential quality, marked by greater immersion, activeness, and positive affect.DiscussionPlayfulness functions as a “color spotlight” rather than “rose-tinted glasses,” with selective influence through “lemonading”—creatively imagining and pursuing positive possibilities to cultivate adaptive, enjoyable experiences while maintaining a clear-eyed realism about challenges. …”
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Men care too: a qualitative study examining women’s perceptions of fathers’ engagement in early childhood development (ECD) during an ECD program for HIV-positive mothers in Malawi... by Linda Richter, Thomas J Coates, Tijana Temelkovska, Pericles Kalande, Evelyn Udedi, Laurie Bruns, Siyenunu Mulungu, Julie Hubbard, Sundeep Gupta, Kathryn Dovel

“…The intervention did not target fathers, but mothers were encouraged to share information with them.Results Interviews were conducted with 29 mothers. …”
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Metal Powder Production by Atomization of Free-Falling Melt Streams Using Pulsed Gaseous Shock and Detonation Waves by Sergey M. Frolov, Vladislav S. Ivanov, Viktor S. Aksenov, Igor O. Shamshin, Fedor S. Frolov, Alan E. Zangiev, Tatiana I. Eyvazova, Vera Ya. Popkova, Maksim V. Grishin, Andrey K. Gatin, Tatiana V. Dudareva

“…The latter is explained by the deficit of energy in the shock-induced cross-flow for the complete atomization of the melt stream, in particular dense and thick (8 mm) streams of the stainless-steel melt. The mass share of particles with a fraction of 0–10 μm can be at least 20%. …”
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Arnold-Chiari Malformation Type II and CYP1B1 Congenital Glaucoma: A Possible Association by Shaikha Aldossari, Amani Al Bakri, Yumna Kamal

“…The aim of reporting this case is to share the findings in this infant as it may be a new association. …”
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Can eating pleasure be a lever for healthy eating? A systematic scoping review of eating pleasure and its links with dietary behaviors and health. by Alexandra Bédard, Pierre-Olivier Lamarche, Lucie-Maude Grégoire, Catherine Trudel-Guy, Véronique Provencher, Sophie Desroches, Simone Lemieux

“…Finally, results from 11 independent interventions suggested that strategies focusing on sensory experiences, cooking and/or sharing activities, mindful eating, and positive memories related to healthy food may be most promising. …”
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Decoding the anomalies: a genome-based analysis of Bacillus cereus group strains closely related to Bacillus anthracis by Thuto Gomolemo Magome, Marius Surleac, Marius Surleac, Ayesha Hassim, Cornelius Carlos Bezuidenhout, Henriette van Heerden, Kgaugelo Edward Lekota

“…Using comparative genomics, pan-genomics and whole genome Single Nucleotide Polymorphism (wgSNP) analysis, a total of 103 B. cereus group genomes were analyzed, including nine newly sequenced isolates from South Africa and a collection of isolates that showed some classification discrepancies, thus classified as “anomalous.”Results and discussionOf the 36 strains identified as B. anthracis in GenBank, 26 clustered phylogenetically with the four confirmed B. anthracis isolates from South Africa and shared 99% ANI. Isolates with less than 99% ANI alignment to B. anthracis exhibited characteristics consistent with B. cereus and/or B. thuringiensis, possessing diverse genetic profiles, insertion elements, resistance genes, and virulence genes features, contrasting with the genetic uniformity of typical B. anthracis. …”
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Model-Based Variation-Aware Optimization for Offset Calibration and Pre-Sensing in DRAM Sense Amplifiers by Dongyeong Kim, Geon Kim, Suyeon Kim, Jewon Park, Sinwook Kim, Hyeona Seo, Chaehyuk Lim, Sowon Kim, Juwon Lee, Jeonghyeon Yun, Hyerin Lee, Jinseok Park, Yongbok Lee, Seungchan Lee, Myoungjin Lee

“…We independently model the OC, charge sharing (CS), and PS operations of DRAM BLSAs to accurately predict both deterministic and stochastic offsets resulting from various operation combinations. …”
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Protocol for an adaptive platform trial of intended service user-derived interventions to equitably reduce non-attendance in eye screening programmes in Botswana, India, Kenya and... by Min Kim, David Macleod, Michael Gichangi, Andrew Bastawrous, Matthew J Burton, Jacqueline Ramke, Oathokwa Nkomazana, James R Carpenter, Sailesh Mishra, Shalinder Sabherwal, Luke Allen, Sarah Karanja, Ari Ho-Foster, Nigel Bolster, Malebogo Tlhajoane, Bakgaki Ratshaa

“…Approvals for individual interventions will be sought from UK and local ethics committees. Results will be shared via local workshops, social media and peer-reviewed publications.Trial registration number ISRCTN53970958.…”
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Surgical treatment of patients with renal cell cancer complicated by specific (tumor) and non-specific thrombosis of the inferior Vena cava by N. V. Vorobev, F. S. Ashyrova, M. P. Golovashchenko, L. O. Petrov, A. D. Kaprin

“…This article presents a clinical case of surgical treatment of a patient with renal cell cancer complicated by massive specific (tumor) and non-specific thrombosis in the presence of reduced parenchymalexcretory function of the contralateral kidney and severe cardiac pathology. Goal: to share experience and demonstrate the results of successful surgical treatment of renal cell carcinoma.…”
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Efficacy of Antimicrobial Photodynamic Therapy for Treating Moderate to Deep Periodontal Pockets in Individuals with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis by João Victor Soares Rodrigues, Mariella Boaretti Deroide, Wilton Mitsunari Takeshita, Valdir Gouveia Garcia, Rafael Scaf de Molon, Leticia Helena Theodoro

“…<b>Background/Objectives:</b> Diabetes mellitus and periodontitis share a significant, bidirectional relationship. …”
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Taxonomic composition and biodiversity of the gut microbiome from patients with irritable bowel syndrome, ulcerative colitis, and asthma by A. Y. Tikunov, A. N. Shvalov, V. V. Morozov, I. V. Babkin, G. V. Seledtsova, I. O. Voloshina, I. P. Ivanova, A. V. Bardasheva, V. V. Morozova, V. V. Vlasov, N. V. Tikunova

“…In the gut microbiota of adults with BA, a decrease in the proportion of Roseburia, Lachnospira, Veillonella sequences was detected, but the share of Faecalibacterium and Lactobacillus sequences was the same as in healthy individuals. …”
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Inter-Cloud Data Security Framework to Build Trust Based on Compliance with Controls by Syed Imran Akhtar, Abdul Rauf, Muhammad Faisal Amjad, Ifra Batool

“…Therefore, this paper proposes an inter-cloud data security framework, which is a set of controls and a mechanism to measure trust for data sharing based on compliance with the controls. The proposed framework for building inter-cloud trust for data security (FBI-TDS) defines a set of data security controls extracted to cover the possible data-related threats linked with various inter-cloud use cases. …”
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Extraction and Optimization of Tanning Material from Osyris lanceolata Barks: Cleaner Leather Tanning Processing by Zerihun Teshome, Tesfaye Agazhi, Tale Gashew, Biniyam Solomon, Tsion Belay, Belete Baye, Efrem Temach

“…However, currently, vegetable tanning and other tanning materials take up a 10–20% share of the leather tanning industry. Even today, most commercial vegetable tanning is a mimosa. …”
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