The initial results of using brolucizumab (Beovu®), an angiogenesis inhibitor, for choroidal neovascularization in patients with age-related macular degeneration by N.S. Zhayvoronok, O.V. Kolenko, L.P. Danilova, E.L. Sorokin

“…Subjectively, all patients noted an improvement in the quality and contrast sensitivity of central vision after treatment. </p> <p> <b>Conclusions</b>: after each injection of brolucizumab, there was a statistically significant progressive reduction in macular parameters, CRT and MV, coupled with an increase in mean BCVA values. …”
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Effect of Acupuncture Exercise Therapy On Isokinetic Muscle Strength and Exercise Ability of Patients after Anterior Cruciate Ligament Reconstruction by Wen YAN, Jiaying MURONG, Shuyi CUI, Wanwen HE, Xun ZHUANG

“…After getting Qi (bring about the desired sensation), the patients were given active knee flexion training, isometric contraction training and closed-chain squat training, and the training method was the same as that of the control group. …”
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Diagnostic Accuracy of Serum Prostate Specific Antigen and Gleason Score in Determining the Presence of Skeletal Metastasis in Prostate Cancer Patients: a Pakistani Perspective by Taimoor Nasir, Syeda Neha Aamer, Saman Waqar, Wafa Omer

“…However, serum PSA is a better and more reliable indicator of bone metastases as it has better sensitivity and specificity values as compared to GS. …”
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Prevalensi Kuman Multi Drug Resistance (MDR) di Laboratorium Mikrobiologi RSUP Dr. M. Djamil Padang Periode Januari 2010 - Desember 2012 by Novilla Rezka Sjahjadi, Roslaili Rasyid, Erlina Rustam, Lily Restusari

“…The result from the research from 6.387 study that shows the number of specimens taken and get sensitivity test, found 3.689 bacterias that have experienced the Multi Drug Resistance (MDR) including Klebsiella sp, Staphylococcus aureus, Enterobacter sp, E.coli sp, Pseudomonas sp, dan Proteus sp. …”
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Fusidic Acid and Lidocaine-Loaded Electrospun Nanofibers as a Dressing for Accelerated Healing of Infected Wounds by Alsulami KA, Bakr AA, Sirwi A, Elfaky MA, Shaik RA, Alshehri BY, Aodah AH, Al Fayez N, Alshehri AA, Almughem FA, Halwani AA, Tawfik EA

“…Herein, two polymer-based nanofibrous systems were developed using poly-lactic-co-glycolic-acid (PLGA) and polyvinylpyrrolidone (PVP) loaded with a combination of an antibiotic (Fusidic acid, FA) and a local anesthetic (Lidocaine, LDC) via electrospinning technique for an expedited healing process by preventing bacterial infections while reducing the pain sensation.Results: The fabricated nanofibers showed an excellent morphology with an average fiber diameter of 556 ± 71 nm and 291 ± 87 nm for the dual drug-loaded PLGA/PVP and PVP nanofibers, respectively. …”
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Comparison of PD-L1 tumor cell expression with 22C3, 28-8, and SP142 IHC assays across multiple tumor types by Jeffrey S Ross, Richard S P Huang, Jake G Maule, Lani K Clinton, Ryon P Graf, Jinpeng Xiao, Geoffrey R Oxnard

“…A total of 81.1% (43/53) lung squamous cell carcinoma, 72.1% (88/122) of lung adenocarcinoma, 69.6% (16/23) of non-small cell lung cancer (NSCLC) not otherwise specified (NOS), and 50.0% (4/8) of small cell lung carcinoma cases were positive with at least one IHC assay.Conclusions Our data suggest that 22C3 is the most sensitive PD-L1 IHC assay for tumor cell expression, followed by 28-8 and in turn by SP-142. …”
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Effects of Hypoxia Stress on Biochemical Indices and Expression of Hypoxia-Related Genes in the Heart of Rainbow Trout (Oncorhynchus mykiss) by Jiuju MA, Jinqiang HUANG, Yongjuan LI, Shenji WU, Lu ZHAO, Yue ZENG

“…Rainbow trout (Oncorhynchus mykiss) is a hypoxia-sensitive fish, and its growth, behavior, metabolism, and immunity are affected in hypoxic environments. …”
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Nucleic Acid Aptamers for Human Norovirus GII.4 and GII.17 Virus-Like Particles (VLPs) Exhibit Specific Binding and Inhibit VLPs from Entering Cells by Cheng C, Sun M, Li J, Xue Y, Cai X, Liu J, Wang X, Xu S, Xie Y, Zhang J

“…Due to antigenic diversity, the discovery of ligands that can sensitively and specifically detect HuNoVs remains challenging. …”
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The role of the Hygiene Department of Stephen Bathory University in the development and promotion of Public Health in Vilnius in the years 1922–1939 by Aistis Žalnora

“…The breadth of the approach of the interwar Vilnius hygienists and doctors, the sensitivity to the social origins of diseases and persistence in combating them by all possible means could serve as an example for today’s doctors. …”
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Identification of EARS2 as a Potential Biomarker with Diagnostic, Prognostic, and Therapeutic Implications in Colorectal Cancer by Wang L, Deng X, Tang J, Gong Y, Bu S, Li Z, Liao B, Ding Y, Dai T, Liao Y, Li Y

“…Additionally, the knockdown of EARS2 inhibited the proliferation, migration, and invasion of CRC cells while enhancing their apoptosis.Conclusion: Elevated expression of EARS2 is associated with abnormal lactate metabolism, immune cell infiltration, altered therapeutic sensitivity, and poorer survival outcomes in CRC. This correlation suggests that EARS2 may serve as a potential target for the diagnosis, prognosis, and therapeutic intervention in 0CRC. …”
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Gut microbiota and blood biomarkers in IBD-Related arthritis: insights from mendelian randomization by Wei Yang, Miao Cui, Peng Yang, Chenlin Liu, Xiuzhen Han, Wenyi Yao, Zhenhua Li

“…To further verify and strengthen our findings, we conducted subsequent sensitivity analyses. These analyses will evaluate the strength of the association between SNPs and the studied biomarkers, as well as post-IBD arthritis, while accounting for variations in SNP distribution among populations and other potential genetic influencing factors. …”
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Microfluidic Synthesis of miR-200c-3p Lipid Nanoparticles: Targeting ZEB2 to Alleviate Chondrocyte Damage in Osteoarthritis by Zheng D, Chen T, Yang K, Yin G, Chen Y, Gui J, Xu C, Lv S

“…The drug release curve, stability, temperature sensitivity, cytotoxicity, and the impact of lipo-AgPEI-miR-200c-3p on the expression of proteins linked to matrix disintegration, apoptosis, and inflammatory factors were all detected.Results: Results showed that the particle size of Lipo-AgPEI-miR-200c-3p was about 130 nm, the Zeta potential was lowered to 1.08± 0.12 mV. …”
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Analisis Faktor dan Metode untuk Menentukan Tipe Kulit Wajah: Tinjauan Literatur by Shinta Dewi Kusumaningrum, Izzati Muhimmah

“…Facial skin is the most sensitive part of the skin hence it is more prone to problems than other parts. …”
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Case based Reasoning Prediksi Waktu Studi Mahasiswa Menggunakan Metode Euclidean Distance dan Normalisasi Min-Max by Henni Endah Wahanani, Made Hanindia Prami Swari, Fawwaz Ali Akbar

“…For precision testing, the system was able to produce the largest values of 90.90%, 43.33% and 100%, respectively. Whereas in the sensitivity test, the system was able to produce values of 90.90%, 40.48%, and 100% respectively. …”
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Elliptic and Quadrangular Flow of Protons in the High-Baryon-Density Region by Shaowei Lan, Zuowen Liu, Like Liu, Shusu Shi

“…The collective flow provides valuable insights into the anisotropic expansion of particles produced in heavy-ion collisions and is sensitive to the equation of the state of nuclear matter in high-baryon-density regions. …”
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Management control for quality in a hospitality business using ARP curves and the multivariate geometric indicator - Control de gestión para la calidad en una empresa hotelera con... by Tomás José Fontalvo Herrera, Juan José Tous Ferrigno, Fabio Mejía Zambrano

“…Methodology: the study adopts a rational quantitative approach combined with a sensitivity analysis that adjusts the Sigma performance level (Z) from 3 to 6. …”
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Editorial by Teddy Surya Gunawan

“…These works underscore the transformative potential of artificial intelligence in improving diagnostic accuracy and protecting sensitive medical data. Another noteworthy contribution is a study on lightning protection systems for large-scale solar photovoltaic plants in Malaysia. …”
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Multicultural values: meeting point of two forces in developing Islamic education by Dwi Mariyono

“…Ethical considerations: the study may have encountered ethical challenges related to participant consent, confidentiality and cultural sensitivity. Future research should prioritize ethical guidelines and considerations to ensure the protection and well-being of participants. …”
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Validity of a machine learning estimation of blood volumes during altitude training by Basile Moreillon, Bastien Krumm, Lena Mettraux, Julian Wackernell, James Spragg, Martin Faulhaber, Raphael Faiss

“…Conversely, predicted values for Hbmass underestimated the actual gains, indicating that the predictive model may not be sensitive enough to discriminate actual variations due to a prolonged hypoxic expopsure. …”
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WRF-Chem simulations of snow nitrate and other physicochemical properties in northern China by X. Wang, X. Wang, T. Che, T. Che, X. Ruan, S. Yue, S. Yue, J. Wang, J. Wang, C. Zhao, C. Zhao, C. Zhao, L. Geng, L. Geng, L. Geng

“…In addition, numerous studies have indicated that snow impurities, especially nitrate, are sensitive to sunlight and can be photolyzed to emit reactive species including NO<span class="inline-formula">₂</span> and HONO, which serve as precursors of O<span class="inline-formula">₃</span> and radicals and disturb the overlying atmospheric chemistry. …”
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