Comparative evaluation of multimarker algorithms for early-stage HCC detection in multicenter prospective studies by Jinlin Hou, Thomas Berg, Arndt Vogel, Teerha Piratvisuth, Jörg Trojan, Enrico N. De Toni, Masatoshi Kudo, Katarina Malinowsky, Peter Findeisen, Johannes Kolja Hegel, Wenzel Schöning, Kairat Madin, Konstantin Kroeniger, Henry Lik-Yuen Chan, Ashish Sharma

“…Our work demonstrates that the GAAD (Cobas) algorithm demonstrated good clinical performance and was as sensitive and specific as the GALAD (Cobas) and GALAD (μTASWAKO) algorithms in differentiating HCC and CLD controls, across all disease stages, etiologies, and geographical regions; therefore, AFP-L3 may have a negligible role in HCC detection. …”
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Validation of Sleep Measurements of an Actigraphy Watch: Instrument Validation Study by Mari Waki, Ryohei Nakada, Kayo Waki, Yuki Ban, Ryo Suzuki, Toshimasa Yamauchi, Masaomi Nangaku, Kazuhiko Ohe

“…The results were not sensitive to the specific participants included, with an ICC range of 0.96-0.97 for sleep duration and 0.79-0.87 for TST when applying our calibration equation to data removing one participant at a time and 0.96-0.97 for sleep duration and 0.79-0.86 for TST when recalibrating while removing one participant at a time. …”
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Effects of open-skill exercise on executive functions in children and adolescents: a systematic review and meta-analysis by Shunding Hu, Peng Shi, Ziyun Zhang, Xiaosu Feng, Kai Zhang, Kai Zhang, Kai Zhang, Teng Jin

“…Both Egger linear regression analyses and literature sensitivity analyses suggested that the Meta-analysis results were stable and reliable.ConclusionOpen-skill exercise has a positive intervention effect on executive functioning in children and adolescents, and strategic skill exercise interventions are more effective. …”
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Evaluation of dried blood spot sampling for real-time PCR malaria diagnostics in a rural setting in Angola by Alejandro Mediavilla, Begoña Febrer-Sendra, Aroa Silgado, Patricia Martínez-Vallejo, Beatriz Crego-Vicente, Arlette Nindia, Carles Rubio Maturana, Lidia Goterris, Joan Martínez-Campreciós, Sandra Aixut, Pedro Fernández-Soto, María Luisa Aznar, Antonio Muro, Inés Oliveira-Souto, Israel Molina, Elena Sulleiro

“…Using field diagnosis as the reference method, the sensitivity of real-time PCR in DBS samples was 77.67% with a specificity of 79.38%. …”
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Budget Impact of Rivaroxaban for the Prevention of Thromboembolic Events after Hip or Knee Replacement in Spain by Xavier Granero Xiberta, Antonio Murcia, José Ricardo Troncoso Durán, Claudio Gómez Zubeldia, Aleix Llorac Moix, Ruth Graefenhain De Codes, Maria Giovana Ferrario, Luis Lizán

“…The annual cost associated with each cohort was estimated based on the mean cost per patient and the estimated distribution of use of rivaroxaban or enoxaparin in the base case scenario and alternative scenario (increase of rivaroxaban use) over the 3 years. A one-way sensitivity analysis was conducted to evaluate the effect that the uncertainty of the input parameters may have on the results of the impact budget. …”
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Une gestion plurielle des illégalismes : négociations et contradictions dans la régulation des eaux usées au Maroc by Pierre-Louis Mayaux, Naïma Fezza, Zhour Bouzidi

“…Thus, the moqqadems are structurally inclined to forbearance because of two main factors : their daily confrontation with users’ capacities of resistance, which dissuades them from repressing too harshly ; and their homology of subaltern position with the latter, which makes them sensitive to the moral economy of subsistence that animates the farmers. …”
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Association of tea consumption with all-cause/cardiovascular disease mortality in the chronic kidney disease population: an assessment of participation in the national cohort by Jin Li, Xing-Ling Chen, Xiao-Lu Ou-Yang, Xiao-Jiao Zhang, Yue Li, Shu-Ning Sun, Ling-Jun Wang, Zhong-Qi Yang, Shi-Hao Ni, Lu Lu

“…Subgroup analysis stratified by sex, age, body mass index (BMI), diabetes, cancer, cardiovascular disease (CVD), and urinary albumin. Sensitivity analysis was performed to ensure the reliability of our findings.Results After adjusting for age, sex, race, education level, marital, annual household income, energy intake, total water intake, protein intake, carbohydrate intake, dietary fiber, sugar beverages, milk whole, total monounsaturated fatty acids, total polyunsaturated fatty acids, total saturated fatty acids, smoking, metabolic equivalent of task for physical activity level (MET-PA), BMI, diabetes, hypertension, urinary albumin, estimated glomerular filtration rate (eGFR), CVD, cancer, serum sodium, serum potassium, and serum phosphorus, setting the individuals without tea consumption record as reference. …”
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Construct validation of a complete postpartum health and well-being patient reported outcome measure: prospective cohort studyAJOG Global Reports at a Glance by Laura J. O'Byrne, BMBS, MSc, PhD, Gillian M. Maher, PhD, Jill M. Mitchell, MB, BCh, BAO, Ali S Khashan, PhD, Richard M. Greene, MB, BCh, BAO, John P. Browne, PhD, Fergus P. McCarthy, MB, BCh, BAO, PhD

“…Conclusion: While this suite of PROMs demonstrated sensitivity in detecting changes in postpartum well-being over time, it did not consistently discern differences based on morbidity (maternal or neonatal) or on delivery type. …”
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Code-Switching in Algerian English as a Foreign Language Speakers’ Facebook Interactions: Exploring Functions and Motives by Saida Tobbi

“…From a social perspective, code-switching allowed participants to express affection, address specific audiences, and navigate cultural sensitivities, such as avoiding taboos. These diverse functions illustrate the adaptive ways in which students use their multilingual resources to enrich their communication and tailor their messages to their intended audiences. …”
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Prognostic significance of cell cycle-associated proteins p16, pRB, cyclin D1 and p53 in resected oropharyngeal carcinoma by Michaela Plath, Martina A. Broglie, Diana Förbs, Sandro J. Stoeckli, Wolfram Jochum

“…Associations between cell cycle protein expression and HR-HPV DNA status were evaluated by calculating sensitivity, specificity, predictive values, and diagnostic odds ratios (DOR). …”
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Risk Factors of Portal Vein Thrombosis in Patients with Different Child-Pugh Classes Liver Cirrhosis by M. Yu. Nadinskaia, Kh. B. Kodzoeva, K. A. Gulyaeva, M.-D. E. Khen, D. I. Koroleva, M. A. Privalov, A. Kh. Tekaeva, V. R. Fedorov, S. G. Prokofev

“…The best model for class A included variceal bleeding, ascites, portal vein diameter, absolute number of neutrophils, for class B — ascites, spleen length, portal vein diameter, malignant tumors / local factors; sensitivity, specificity, accuracy and AUC were 79.3 %, 90 %, 86.5 %, 0.897 and 73.3 %, 68.3 %, 69.9 %, 0.789, respectively.Conclusion. …”
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Conditional cash transfer program and child mortality: A cross-sectional analysis nested within the 100 Million Brazilian Cohort. by Dandara Ramos, Nívea B da Silva, Maria Yury Ichihara, Rosemeire L Fiaccone, Daniela Almeida, Samila Sena, Poliana Rebouças, Elzo Pereira Pinto Júnior, Enny S Paixão, Sanni Ali, Laura C Rodrigues, Maurício L Barreto

“…The main limitation of our methodology is that our propensity score approach does not account for possible unmeasured confounders. Furthermore, sensitivity analysis showed that loss of nameless death records before linkage may have resulted in overestimation of the associations between BFP participation and mortality, with loss of statistical significance in municipalities with greater losses of data and change in the direction of the association in municipalities with no losses.…”
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Les voyages reproductifs vers la Tunisie : l’intime au prisme des pratiques de l’assistance médicale à la procréation by Irene Maffi, Betty Rouland, Carole Wenger

“…The reproductive routes taken, invite us to decentralise the gaze and focus on other types of circulation from the Maghreb to the southern shore of the Sahara and even beyond (European and Gulf countries where the TRA have emigrated); to spatialise the narratives of couples in motion while grasping the globalised social transformations they characterise (biomobility, bioeconomies, biotechnologies); and to understand the sensitive nature of these narratives, which carry a very strong emotional charge. …”
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Development of a Prediction Model and Risk Score for Self-Assessment and High-Risk Population Identification in Liver Cancer Screening: Prospective Cohort Study by Xue Li, Youqing Wang, Huizhang Li, Le Wang, Juan Zhu, Chen Yang, Lingbin Du

“…The model exhibited excellent discrimination in both the development and validation sets, with areas under the curve (AUC) of 0.802, 0.812, and 0.791 for predicting liver cancer at the 1-, 3-, and 5-year periods in the development set and 0.751, 0.763, and 0.712 in the validation set, respectively. Sensitivity analyses applied to the subgroups of participants without cirrhosis and with a negative or unknown HBsAg status yielded similar performances, with AUCs ranging from 0.707 to 0.831. …”
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Four weeks of slow-paced breathing: a longitudinal, randomized, placebo-controlled study of the autonomic nervous system by Nicolas Bourdillon, Arnaud Rochat, Vanessa Hoop, Grégoire P. Millet

“…Before and after the interventional period, they performed baroreflex sensitivity (BRS) and heart rate variability (HRV) assessments in our laboratory (labPRE and labPOST). …”
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Elevating larval source management as a key strategy for controlling malaria and other vector-borne diseases in Africa by Fredros Okumu, Sarah J. Moore, Prashanth Selvaraj, Arnon Houri Yafin, Elijah O. Juma, GloriaSalome G. Shirima, Silas Majambere, Andy Hardy, Bart G. J. Knols, Betwel J. Msugupakulya, Marceline Finda, Najat Kahamba, Edward Thomsen, Ayman Ahmed, Sarah Zohdy, Prosper Chaki, Peter DeChant, Kimberly Fornace, Nicodem Govella, Steven Gowelo, Emmanuel Hakizimana, Busiku Hamainza, Jasper N. Ijumba, William Jany, Hmooda Toto Kafy, Emmanuel W. Kaindoa, Lenson Kariuki, Samson Kiware, Eliningaya J. Kweka, Neil F. Lobo, Dulcisária Marrenjo, Damaris Matoke-Muhia, Charles Mbogo, Robert S. McCann, April Monroe, Bryson Alberto Ndenga, Halfan S. Ngowo, Eric Ochomo, Mercy Opiyo, Richard Reithinger, Chadwick Haadezu Sikaala, Allison Tatarsky, David Takudzwa, Fedra Trujillano, Ellie Sherrard-Smith

“…What is needed now is a significant boost in the financial resources and public health administration structures necessary to train, employ and deploy local-level workforces tasked with suppressing mosquito populations in scientifically driven and ecologically sensitive ways. In conclusion, having WHO guidelines that recognize LSM as a key intervention to be delivered in multiple contextualized forms would open the door to increased flexibility for funding and aid countries in implementing the strategies that they deem appropriate. …”
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Le tourisme et l’imaginaire érotique à Paris durant la guerre : Français et Allemands pendant l’Occupation, 1940-1944 by Bertram M. Gordon

“…Leur séjour à Paris, une ville à l’imaginaire sensuel bien établi outre Rhin, leur ouvrit des possibilités jusqu’alors insoupçonnées de rencontres sexuelles relevant aussi bien des imaginaires que du vécu. …”
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AI-Driven Innovations for Early Sepsis Detection by Combining Predictive Accuracy With Blood Count Analysis in an Emergency Setting: Retrospective Study by Tai-Han Lin, Hsing-Yi Chung, Ming-Jr Jian, Chih-Kai Chang, Hung-Hsin Lin, Chiung-Tzu Yen, Sheng-Hui Tang, Pin-Ching Pan, Cherng-Lih Perng, Feng-Yee Chang, Chien-Wen Chen, Hung-Sheng Shang

“…Machine learning models, including light gradient boosting machine (LGBM), random forest classifier, and gradient boosting classifier, were developed using CBC+DIFF data and were assessed using metrics such as area under the curve, sensitivity, and specificity. The best-performing model was integrated into the AI-CDSS, with its implementation supported through workshops and training sessions. …”
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Effect of Situational Interactive Respiratory Training System on Patients with Respiratory Dysfunction after Stroke by TAN Lishuang, WANG Na, ZHAO Xiaoxue, DU Tianshu, ZHANG Yan

“…Then, the patient faced the screen and aligns his mouth with the pressure sensor of the training system to perform lip-respiratory breathing. …”
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Analyzing power errors in the optical pumping system of atomic spin comagnetometers by Jiale QUAN, Ye LIU, Longyan MA, Wenfeng FAN, Wei QUAN

“…The spin exchange relaxation-free (SERF) atomic comagnetometer is a highly sensitive device designed to measure rotation rates with extreme precision. …”
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