A Mendelian randomization study of depression and risk of cervical cancer (抑郁和宫颈癌发病风险相关的孟德尔随机化分析) by LIU Yinxia (刘银侠), YU Ping (俞萍), XU Yang (徐阳)

“…Weighted median method and MR-Egger provided the similar result. Sensitivity analysis found that no single SNP was strongly or reversely driving the overall effect for causal estimates. …”
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Prevalence and associated factors of self-reported oral health problems among adults in the Fanteakwa districts in Ghana by Joana Kwabena-Adade, Enoch Aninagyei, Joy Ato Nyarko

“…Whereas the self-reported oral health problems were tooth ache, swollen gum, bleeding gum, sensitive tooth/teeth, hole in tooth/teeth, discoloured tooth/teeth and mouth odour. …”
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Correlation of muscle strength, information processing speed and cognitive function in the elderly with cognitive impairment——evidence from EEG by Xin Xin, Qing Liu, Shuqi Jia, Shufan Li, Peng Wang, Xingze Wang, Xing Wang

“…The α1 power values at F7 + F8 and T5 + T6 were identified as sensitive EEG indicators for muscle strength and information processing speed. …”
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Effects of aerobic exercise on cognitive function and quality of life in patients with Alzheimer’s disease: a systematic review and meta-analysis by Linlin Yang, Zhichao Yuan, Chenggen Peng

“…To investigate possible sources of heterogeneity between studies, meta-regression was carried out using Stata MP V.18.0 and V.14.0 software, standardised mean differences (SMDs) and 95% CIs were computed, and data were reviewed using Review Manager V.5.4 software, which was made available by the Cochrane Collaboration. Sensitivity analyses were employed to ascertain the stability and reliability of the results, and funnel plots and Egger’s test were employed to check for publication bias. …”
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Isoacid supplementation influences feed sorting, chewing behaviors, and enteric methane emissions differentially in mid-lactation dairy cows depending on dietary forage level by M.R.A. Redoy, S. Ahmed, M. Bulnes, D.H. Kleinschmit, M.E. Uddin

“…Enteric CH4 and chewing activity (rumination and eating time) were measured using the GreenFeed system and sensor-based ear tag system, respectively. The particle size of each diet and ort from individual cows was measured using the Penn State Particle Separator, and a sorting index was calculated. …”
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Construction and Comparison of Machine Learning-Based Risk Prediction Models for Major Adverse Cardiovascular Events in Perimenopausal Women by Chen A, Chang X, Bian X, Zhang F, Ma S, Chen X

“…The prediction performance of the model was evaluated in terms of accuracy, sensitivity, specificity, and area under the subject operating characteristic curve (AUC).Results: A total of twenty-six candidate variables were included. …”
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Specifically blocking αvβ8-mediated TGF-β signaling to reverse immunosuppression by modulating macrophage polarization by Cuicui Guo, Hui Sun, Yulei Du, Xiaodong Dai, Yu Pang, Zhen Han, Xinhui Xiong, Shaowei Li, Junhua Zhang, Qingbing Zheng, Xun Gui

“…Combining αvβ8 targeting with PD-1 treatment markedly increases the sensitivity of immune-excluded tumors. These results support further clinical evaluation of αvβ8 antibodies. …”
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TGF-β induces cholesterol accumulation to regulate the secretion of tumor-derived extracellular vesicles by Dorival Mendes Rodrigues-Junior, Chrysoula Tsirigoti, Konstantina Psatha, Dimitris Kletsas, Michalis Aivaliotis, Carl-Henrik Heldin, Aristidis Moustakas

“…Notably, inhibition of MEK or cholesterol synthesis, which impaired TGF-β-induced EV secretion, sensitized cancer cells to chemotherapeutic drugs. Furthermore, proteomic profiling of two distinct EV populations revealed that EVs secreted by TGF-β-stimulated cells were either depleted or enriched for different sets of cargo proteins. …”
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Sex differences in the relationships between 24-h rest-activity patterns and plasma markers of Alzheimer’s disease pathology by Maxime Van Egroo, Elise Beckers, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Heidi I. L. Jacobs

“…Importantly, interaction models demonstrated that male participants were driving the observed relationships between IV and plasma NfL (t(84) = 4.05, P < 0.001) or GFAP (t(84) = 3.60, P < 0.001), but also revealed a male vulnerability in models testing interactions with p-tau181 (IV: t(76) = 3.71, P < 0.001; IS: t(76) = -3.30, P = 0.001) and p-tau231 (IV: t(82) = 3.28, P = 0.002). Sensitivity analyses further showed that accounting for potential confounding factors such as APOE genotype, depression, and self-reported symptoms of possible sleep apnea did not modify the observed relationships. …”
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Digital Home-Based Self-Monitoring System for People with Heart Failure: Protocol for Development of SmartHeart and Evaluation of Feasibility and Acceptability by Ralph Maddison, Rebecca Nourse, Reza Daryabeygikhotbehsara, Teketo Kassaw Tegegne, Paul Jansons, Jonathan Charles Rawstorn, John Atherton, Andrea Driscoll, Brian Oldenburg, Rajesh Vasa, Vassilis Kostakos, Tilman Dingler, Gavin Abbott, Paul Scuffham, Jo-Anne Elizabeth Manski-Nankervis, Dominika Kwasnicka, Finn Kensing, Sheikh Mohammed Shariful Islam, Anthony Maeder, Yuxin Zhang

“…The system collects physiological, symptom, and behavioral data through wireless sensors and self-reports from users. These data are processed and analyzed to provide personalized health insights, self-care support, and alerts in case of health deterioration. …”
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Comprehensive pan-cancer analysis reveals NTN1 as an immune infiltrate risk factor and its potential prognostic value in SKCM by Fuxiang Luan, Yuying Cui, Ruizhe Huang, Zhuojie Yang, Shishi Qiao

“…Lastly, we constructed a nomogram based on NTN1 in SKCM and investigated its association with drug sensitivity. NTN1 expression was significantly associated with tumor immune infiltration, molecular subtypes, and clinicopathological features in various cancers. …”
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Circulating Soluble ST2 Predicts All-Cause Mortality in Severe Heart Failure Patients with an Implantable Cardioverter Defibrillator by Zhi-wei Hou, Hai-bo Yu, Yan-chun Liang, Yang Gao, Guo-qing Xu, Min Wu, Zhu Mei, Zu-lu Wang, Zhi-guo Li, Yu-ying Li, Hai-xu Song, Jia-yin Li, Ya-ling Han

“…The best sST2 cutoff for predicting all-cause death was 43.42671 ng/ml (area under the curve: 0.72, sensitive: 0.69, and specificity: 0.69). Compared to patients with sST2 levels below 43.42671 ng/ml, the risk of all-cause mortality was higher in those with values above the threshold (5.1% vs. 21.2%, P=0.002). …”
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Gestational Weight Gain and Small for Gestational Age in Obese Women: A Systematic Review and Meta-Analysis by Wen Chen, Beiyi Li, Kexin Gan, Jing Liu, Yajing Yang, Xiuqin Lv, Huijuan Ma

“…Subgroup analyses were conducted, and publication bias was assessed by funnel plots and Egger’s test. Sensitivity analyses were performed for three groups of obese people (I: BMI 30–34.9 kg/m2, II: BMI 35–39.9 kg/m2, and III: BMI ≥ 40 kg/m2) to examine the association of obesity and SGA. …”
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Carriage of Extended-Spectrum-β-Lactamase- and AmpC-β-Lactamase-Producing Enterobacteriaceae (ESBL-PE) in Healthy Community and Outpatient Department (OPD) Patients in Nepal by Dipendra Kumar Mandal, Shiv Kumar Sah, Shyam Kumar Mishra, Sangita Sharma, Hari Prasad Kattel, Sanjeet Pandit, Pranav Kumar Yadav, Ujjwal Laghu, Rajani Lama, Niranjan Prasad Sah, Jeevan Bahadur Sherchand, Keshav Parajuli, Anup Bastola, Sher Bahadur Pun, Basista Prasad Rijal, Bharat Mani Pokharel

“…All isolates were highly sensitive (100%) to imipenem in both OPD and healthy participants. …”
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Pooled prevalence and associated factors of traditional uvulectom among children in Africa: A systematic review and meta-analysis. by Solomon Demis Kebede, Kindu Agmas, Demewoz Kefale, Amare Kassaw, Tigabu Munye Aytenew

“…Missing data was handled by random effect model and sensitivity analysis. Data extraction was conducted fromNovember 6 to December 23, 2023.…”
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Development and Validation of an UHPLC-MS/MS Method for Quantification of DMAG in Rat Plasma and Its Application in a Preliminary Pharmacokinetic Study in Thrombocytopenia Rats by Yan Li, Yuqing Wang, Zhiqiang Zhao, Yunxia Li, Cheng Peng, Jianming Wu

“…Therefore, we aimed to establish a simple, rapid, and sensitive UHPLC-MS/MS method for quantifying DMAG and study its pharmacokinetic behavior in this study. …”
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Construction of a diagnostic model for chronic mountain sickness among young male migrants to high-altitude areas by ZHANG Quan, CHEN Jian, LIU Bao

“…The area under the curve （AUC） value of the CMS diagnostic model in the training set and test set was 0.821 （95%CI： 0.756~0.886） and 0.821 （95%CI： 0.700~0.944）， the specificity was 66.30% and 73.90%， the sensitivity was 89.50% and 81.20%， respectively， indicating good discrimination ability. …”
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Efficacy and safety of sequential therapy for primary osteoporosis with bone formation promoters followed by bone resorption inhibitors: a meta-analysis by Yuxin Liu, Xin Liu, Yuefeng Wu, Tao Luo

“…Data from clinical studies that met the eligibility criteria were extracted, and quality assessment and meta-analysis were performed using RevMan v5.4 and Stata v15.0. Sensitivity and subgroup analyses were performed to find the source of heterogeneity and discover more findings. …”
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Association of preoperative body mass index with postoperative complications and survival for patients with gastric cancer: A systematic review and meta-analysis. by Zhenzhen Li, Lili Cui, Jing Sun, Wanlu Liu

“…Additionally, exploratory sensitivity and subgroup analyses were performed.<h4>Results</h4>Twenty-two studies involving 41,144 patients with gastric cancer were included for quantitative analysis. …”
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Efficacy and safety of acupuncture monotherapy or combined with pelvic floor muscle training for female stress urinary incontinence: a systematic review and meta-analysis by Tong Jiang, Zhi-Yu Dong, Ying Shi, Yang-Qing Zhou, Hong-Bin Zhang, Yi Gong

“…The results were robust for the sensitivity analyses. EA was not associated with an increased incidence of adverse events compared to placebo EA (RR = 1.08, 95% CI 0.50 to 2.35, I2 = 0%). …”
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