The effect of supplementation with type I and type III collagen peptide and type II hydrolyzed collagen on pain, quality of life and physical function in patients with meniscopathy... by Ahmet Serhat Genç, Ali Kerim Yılmaz, Berna Anıl, Esra Korkmaz Salkılıç, Enes Akdemir, Berna Güzel, Ahmet Mor, Hacı Ahmet Yarar, Nizamettin Güzel, Lokman Kehribar

“…Patients completed the Visual Analog Scale (VAS), Western Ontario and McMaster Universities Osteoarthrtis Index (WOMAC), Knee Injury and Osteoarthritis Outcome Score Physical Function Short Form (KOOS-PS), Oxford Knee Score (OKS), Tampa Scale for Kinesiophobia (TSK), Short Form Health Survey (SF-12), Lower Extremity Functional Scale (LEFS), Foot Function Index (FFI), proprioceptive sensation, Timed Up and Go (TUG), 6-Minute Walking Test (6MWT), The Five Repetition Sit to Stand Test (5STS), Stair Climbing Test (SCT), Berg Balance Scale (BBS) and back and leg strength tests and scales were applied. …”
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Gcn2 rescues reprogramming in the absence of Hog1/p38 signaling in C. neoformans during thermal stress by David Goich, Amanda L. M. Bloom, Sean R. Duffy, Maritza N. Ventura, John C. Panepinto

“…Our results show that compensatory signaling occurs via the Gcn2 pathway when Hog1 is deleted, and that disruption of both pathways increases sensitivity to thermal stress. Importantly, our study highlights the insufficiency of using single-gene deletion mutants to study gene function, since many phenotypes associated with Hog1 deletion were driven by Gcn2 signaling in this background, rather than loss of direct Hog1 activity.…”
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Value of Plasma NGAL and Creatinine on First Day of Admission in the Diagnosis of Cardiorenal Syndrome Type 1 by Hao Phan Thai, Bao Hoang Bui, Tien Hoang Anh, Minh Huynh Van

“…The optimal cutoff plasma NGAL for diagnosing CRS1 was >353.23 ng/ml, area under curve (AUC) 0.732 (95% CI 0.65–0.80, p<0.001), sensitivity 74.47%, specificity 68.48%, positive predictive value 54.7%, and negative predictive value 84%. …”
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Antimicrobial Profiling of Bacteria Isolated from Fish Sold at Informal Market in Mufakose, Zimbabwe by Claudious Gufe, Tinashe Canaan Hodobo, Bernard Mbonjani, Otlia Majonga, Jerikias Marumure, Shuvai Musari, Gilbert Jongi, Pious Vengesayi Makaya, Jairus Machakwa

“…A cross-sectional study was carried out to (i) isolate and phenotypically identify bacteria from 36 fish samples from informal market in Mufakose, Harare, and (ii) determine the antibiotic sensitivity pattern of the isolated bacteria against ten available antibiotics (ampicillin 10 μg, gentamycin 30 μg, penicillin G 10 μg, erythromycin 15 μg, tetracycline 30 μg, kanamycin 30 μg, neomycin 10 μg, cloxacillin 5 μg, lincomycin 15 μg, and sulfamethoxazole 25 μg) using the Kirby–Bauer disk agar diffusion method. …”
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Multidrug resistance of Pseudomonas aeruginosa: do virulence properties impact on resistance patterns? by Poulomi Saha, Rubaiya Binte Kabir, Chowdhury Rafiqul Ahsan, Mahmuda Yasmin

“…An antibiogram was performed to investigate the pathogen’s antibiotic sensitivity pattern against 14 widely used antibiotics in Bangladesh. …”
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Combinatorial functionomics identifies HDAC6-dependent molecular vulnerability of radioresistant head and neck cancer by Sharon Pei Yi Chan, Celestia Pei Xuan Yeo, Boon Hao Hong, Evelyn Mui Cheng Tan, Chaw Yee Beh, Eugenia Li Ling Yeo, Dennis Jun Jie Poon, Pek Lim Chu, Khee Chee Soo, Melvin Lee Kiang Chua, Edward Kai-Hua Chow

“…Results We report the therapeutic potential of combining panobinostat (pan-HDAC inhibitor) with AZD7762 (CHK1/2 inhibitor; AstraZeneca) or ionizing radiation (IR) to re-sensitize RR-HNC cells and showed increased DNA damage underlying enhanced synergy. …”
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Therapy for Dupuytren’s Disease (II): Collagenase Therapy vs. Limited Fasciectomy—A Long-Term Comparative Study by Nikolaus Wachtel, Francesca Romana Dingler, Constanze Kuhlmann, Sinan Mert, Elisabeth Maria Haas-Lützenberger, Verena Alt, Nicholas Moellhoff, Riccardo Giunta, Wolfram Demmer

“…Finger extension (Tubiana stage), strength, sensitivity, the effect of possible risk factors, and patient-reported outcome measures (PROMs) were compared between the two groups. …”
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The Relationship between Landing Error Scoring System Performance and Injury in Female Collegiate Athletes by Peter Lisman, Joshua N. Wilder, Joshua Berenbach, Enric Jiao, Bethany Hansberger

“…The LESS was automatically scored using a Microsoft Kinect sensor and Athletic Movement Assessment software (PhysiMax®). …”
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Identification of prognostic biomarker of non-small cell lung cancer based on mitochondrial permeability transition-driven necrosis-related genes and determination of anti-tumor ef... by Zhifei Ma, Wen Chen, Aiping Zhang, Xiaokang Shen, Lin Zheng

“…Three gene were strongly associated with most immune cells, immune checkpoints, and drugs sensitivity. RT-qPCR confirmed that expression levels of three genes in tissues or cells were consistent with the results of bioinformatics analysis. …”
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Construction of a prognostic prediction model for colorectal cancer based on 5-year clinical follow-up data by Boao Xiao, Min Yang, Yao Meng, Weimin Wang, Yuan Chen, Chenglong Yu, Longlong Bai, Lishun Xiao, Yansu Chen

“…The model performance was comprehensively assessed using multiple metrics, including accuracy, F1 score, Brier score, sensitivity, specificity, positive predictive value, negative predictive value, receiver operating characteristic curve, calibration curve, and decision curve analysis curve. …”
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Does Proteinuria Measured by Dipstick Method Reflect Reality in Patients with Preeclampsia? by Cenk Soysal, Mehmet Murat Işıkalan

“…The dipstick test was found to have a sensitivity of 81.4% and a specificity of 85.2%. The dipstick test results were grouped as 0, +1, +2, +3, and higher. …”
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Neurotrophin-3 as a mediator in the link between PM2.5 exposure and psychiatric disorders: A Mendelian randomization study by Yuan Zhang, Wei Wang, Xuening Zhang, Ran Jing, Xin Wen, Peng Xiao, Xinjie Liu, Zengle Zhao, Tongmin Chang, Yufei Li, Wen Liu, Chenxi Sun, Xiaorong Yang, Lejin Yang, Ming Lu

“…Further analysis using two-step MR revealed that Neurotrophin-3 mediated 9.86 % of the PM2.5-ADHD association and 5.88 % of the PM2.5-schizophrenia association. Sensitivity analyses supported these findings. Conclusions: This TSMR analysis provides a comprehensive examination of the causal relationship between PM2.5 exposure and nine common psychiatric disorders, with mediation analysis offering insight into the underlying mechanisms. …”
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Carcinogenic and non-carcinogenic risk estimation of indoor TVOCs, RSPM, FPM and SFPM on young women dwellers: a case study from the capital city of Uttar Pradesh, India by Farheen Zehra, Samridhi Dwivedi, Mohd Akbar Ali, P. S. Rajinikanth, Alfred Lawrence

“…Envirotech APM 550 for RSPM and FPM, APM 577 for SFPM and portable sensor-based instrument (BR-SMART) were used to measure TVOCs. …”
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The role of adenosine monophosphate-activated protein kinase and serum amyloid A proteins in the early diagnosis of neonatal sepsis by P.A. Orujova, N.H. Sultanova

“…Current diagnostic markers such as C-reactive protein (CRP) and procalcitonin (PCT) lack specificity and sensitivity for early diagnosis, highlighting the need for more reliable biomarkers. …”
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Clinical Value of Asymmetrical Dimethylarginine Detection in Patients with Connective Tissue Disease-Associated Pulmonary Arterial Hypertension by Juan Liu, Qiang Fu, Lili Jiang, Youlian Wang

“…Using the receiver operating characteristic (ROC) curve analysis, at the cutoff level of 0.810 μmol/L, ADMA showed good diagnostic efficacy as follows: sensitivity was 97.7%, specificity was 75.6%, and the area under the curve (AUC) was 0.947 (P<0.001). …”
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Prevalence of cardiovascular symptoms in post-acute COVID-19 syndrome: a meta-analysis by Li-wei Huang, Hua-min Li, Bei He, Xiao-bo Wang, Qi-zhi Zhang, Wen-xing Peng

“…The primary outcomes included hypertension, palpitations, and chest pain, with pooled effect estimate reported as proportions and odds ratios (ORs) with 95% confidence intervals (CIs). Sensitivity and subgroup analysis were performed to assess the robustness of the results and to identify sources of heterogeneity. …”
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Development of a sequential laser microdissection tissue cuts workflow for the spatial and quantitative analysis of drugs in fresh frozen tissue sections. by Elias Maris, Farid Jahouh, Kathleen Allaerts, Rob Vreeken

“…Although this method relying on manual ROIs selection is rather sensitive compared to traditional MSI methods, it lacks the throughput needed to screen entire tissue sections. …”
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Study of the effectiveness of vacuum-aspiration breast biopsy in patients with complete clinical response after neoadjuvant polychemotherapy in complex treatment of breast cancer by K. V. Maksimov, D. V. Bagdasarova, A. D. Zikiryakhodzhaev, A. A. Kolomeytseva, M. L. Mazo, V. S. Surkova, F. N. Usov, I. A. Eremeeva, A. N. Gerasimov

“…No statistically significant results of the association between complete pathomorphological response and the molecular-biological type of breast cancer were obtained (p &gt; 0.05), however, there is a tendency towards the greatest number of complete pathomorphological responses in Her2-neu-positive (luminal – 100 %, non-luminal – 90.9 %) and triple-negative (87.50 %) types of breast cancer. The overall sensitivity of the method was 25.0 % (CI 6.8–60.2 %); specificity – 100 % (CI 88.1–100 %); false-negative result (presence of tumor cells in the surgical material and a negative result of VAB) – 9.1 % (CI 3.4–20.2 %); false-positive result (absence of tumor cells in the surgical material and a positive result of VAB) – 0 % (CI 0–10.6 %). …”
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Concurrent Force Feedback on Load Symmetry in Total Knee Arthroplasty Patients by Steni Sackiriyas, Becky Heinert, Drew Rutherford, Gwen M Fritz, Thomas W Kernozek

“… # Study design Case-series study # Methods This observational, repeated-measures study design examined the effect of concurrent force feedback training on the mean and standard deviation of load symmetry index during the leg press and squat exercises in 26 patients with TKA in an outpatient sports medicine clinic.The load asymmetry was measured with loadpad sensors placed underneath the each extremity during leg press and squat (baseline), after one training session consisting of concurrent force feedback during these exercises within a single physical therapy session (post feedback), and after seven to ten days of a washout period (post retention). …”
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Searching for string bosenovas with gravitational wave detectors by Dawid Brzeminski, Anson Hook, Junwu Huang, Clayton Ristow

“…We work out the spectral density of this acceleration, and project that modern accelerometers and equivalence principle tests can be sensitive to the passing of these strings.…”
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