Low Systemic Inflammation Response Index Predicts Good Prognosis in Locally Advanced Pancreatic Carcinoma Patients Treated with Concurrent Chemoradiotherapy by Erkan Topkan, Huseyin Mertsoylu, Ahmet Kucuk, Ali Ayberk Besen, Ahmet Sezer, Duygu Sezen, Yasemin Bolukbasi, Ugur Selek, Berrin Pehlivan

“…ROC curve analyses determined the ideal SIRI cutoff that exhibiting a significant link with OS and PFS outcomes at the rounded 1.6 point (AUC: 74.3%; sensitivity: 73.8%; specificity: 70.1%).The SIRI <1.6 patients (N=58) had significantly superior median PFS (13.8 versus 6.7 months; P<0.001) and OS (28.6 versus 12.6 months; P<0.001) lengths than SIRI ≥1.6 patients (N=96), respectively. …”
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Metabolic Effects of Testosterone Hormone Therapy in Normal and Orchiectomized Male Rats: From Indirect Calorimetry to Lipolytic Enzymes by Mahmoud Mustafa Ali Abulmeaty, Ali Madi Almajwal, Mohamed Farouk ElSadek, Mohamed Y Berika, Suhail Razak

“…After one week, FI and wt were automatically recorded, indirect calorimetry parameters were measured, and blood samples were collected to measure T, ghrelin, insulin, growth hormone (GH), glucose, hormone-sensitive lipase (HSL), adipocyte triglyceride lipase (ATGL), free fatty acids (FFA), and lipid profiles. …”
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Association between glyphosate exposure and cardiovascular health using “Life’s Essential 8” metrics in US adults by Yuankang Zhu, Zhenlin Yang, Yuhao Chen, Lingzi Qian, Changning Hao, Liangshi Hao, Boshen Yang, Junli Duan

“…Further subgroup analysis and sensitive analysis were conducted to confirm the results. …”
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Single-cell RNA sequencing and immune microenvironment analysis reveal PLOD2-driven malignant transformation in cervical cancer by Zhiheng Lin, Fengxin Wang, Renwu Yin, Shengnan Li, Yuquan Bai, Baofang Zhang, Chenlin Sui, Hengjie Cao, Dune Su, Lianwei Xu, Honghong Wang

“…Furthermore, assessments of drug sensitivity and functional enrichment were carried out.ResultsEight cell types were identified, with EPCs showing high proliferative and stemness features. …”
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Ultrasonic characteristics of inserted central catheter related fibroblastic sleeve by Zhifei Ben, Jue Wang, Jinyong Zhan, Kaiying Xu

“…With the pathological results as the gold standard, the optimal cut-off value for the diagnosis of fibroblastic sleeve with thrombosis was 2.58 mm, and the sensitivity and specificity of the diagnosis were 95.45% and 96.08%. …”
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ASSESSING THE IMPACT OF ACIDIC DRINKS ON THE STRUCTURAL INTEGRITY OF ENAMEL AND THEIR CONSEQUENCES FOR DENTAL AESTHETICS by Berivan Laura Rebeca Buzatu, Roxana Buzatu, Atena Galuscan, Delia Abrudan Luca, Ruxandra Sava Rosianu, Octavia Balean, Titus Vlase, Daniela Jumanca

“…Conclusions: In conclusion, the excessive and frequent consumption of acidic beverages results in irreversible enamel demineralization, leading to aesthetic concerns such as white spots, discoloration, surface roughness, and an increased risk of tooth sensitivity or loss. Additionally, the method of consumption—particularly the tendency to a prolonged the contact between these beverages and the dental structure—exacerbates the potential for damage. …”
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MRI to digital medicine diagnosis: integrating deep learning into clinical decision-making for lumbar degenerative diseases by Baoyi Ke, Wenyu Ma, Junbo Xuan, Junbo Xuan, Yinghao Liang, Liguang Zhou, Wenyong Jiang, Jing Lin, Guixiang Li

“…Through classification of the testing set, the deep learning algorithm showed higher sensitivity, specificity, and accuracy in diagnosing lumbar spine MR images compared to manual identification. …”
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Cultural Adaptation of an Aboriginal and Torres Strait Islanders Maternal and Child mHealth Intervention: Protocol for a Co-Design and Adaptation Research Study by Sana Ishaque, Ola Ela, Chris Rissel, Karla Canuto, Kerry Hall, Niranjan Bidargaddi, Annette Briley, Claire T Roberts, Sarah Jane Perkes, Anna Dowling, Billie Bonevski

“…ConclusionsA co-designed, culturally sensitive, and effective digital health intervention is likely to support Indigenous mothers and their children facing health disparities due to the disruption of Indigenous culture by colaying a foundation for a potential clinical trial and wider implementation. …”
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Spatio-Temporal Dynamics of Sediment Transport Pathways: Sand Apron Bars and Islands of Tokelau and Kiribati, Central Pacific by Eugene C. Rankey, Tion Uriam, Mika Perez

“…Understanding such local influences is requisite to predictive understanding of how global change might impact these sensitive seascapes.…”
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Estimation the pH of CO2-saturated NaCl solutions using gene expression programming: Implications for CO2 sequestration by Mohammad Rasool Dehghani, Parirokh Ebrahimi, Moein Kafi, Hamed Nikravesh, Yousef Kazemzadeh

“…Kernel density estimation plots confirmed the model generally underestimated pH values. Sensitivity analysis using Spearman's correlation coefficients confirmed pressure had the highest and temperature had the lowest influence on pH output. …”
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Extracellular volume fraction and native T1 mapping in diabetic cardiomyopathy: a comprehensive meta-analysis by Ahmed Marey, Ali Alabdullah, Hossam Ghorab, Fatima Ali, Jawdat Abdulla, Akhil Narang, Muhammad Umair

“…Meta-regression assessed the correlation between ECV and HbA1C. Sensitivity and subgroup analyses were performed to explore heterogeneity. …”
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Clinical and microbiological characteristics and prognosis of invasive infection caused by Klebsiella pneumoniae in the community by Hongkui Sun, Hanlin Zhang, Wenqing Lai, Li Lei, Jianwei Li, Miaolian Chen, Haijun Li, Zhanyuan Zhao

“…The treatment of cKp invasive infections remains inconclusive between "heavy-handed strikes" and "sensitivity is sufficient". Focusing solely on the liver and lungs while neglecting infection sites outside of these organs can lead to catastrophic results, which should be avoided during treatment.…”
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Comparing Balance Performance on Force Platform Measures in Individuals with Parkinson’s Disease and Healthy Adults by Cathy C. Harro, Amanda Kelch, Cora Hargis, Abigail DeWitt

“…The PD cohort demonstrated significantly greater postural instability on the sensory organization test (SOT) measures (P=0.013, CI-95% = 1.286 to 10.37) and slower movement velocity on the limits of stability (LOS) test (P=0.001, CI-95% = 0.597 to 1.595) than the healthy cohort, suggesting that these tests were sensitive to detect sensory integration and voluntary postural control deficits in the PD cohort. …”
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Functional Status of Pancreatic α and β Cells in Type 2 Diabetes Mellitus Patients with Different Plasma Triglyceride Levels: A Retrospective Analysis by Hang Guo, Chunlei Ma, Xiaoming Wu, Congqing Pan

“…In addition to the increase in TG levels, the insulin sensitivity index (ISI), homeostasis model assessment for β-cell function index (HOMA-β), ΔI30/ΔG30, and AUCI displayed a reducing trend. …”
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To what extent is the description of streets important in estimating local air quality: a case study over Paris by A. Squarcioni, A. Squarcioni, Y. Roustan, M. Valari, Y. Kim, K. Sartelet, L. Lugon, F. Dugay, R. Voitot

“…The performance of MUNICH appears to be highly sensitive to the friction velocity, a parameter influenced by the anthropogenic heat flux used in the WRF model. …”
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The application of a clinical-multimodal ultrasound radiomics model for predicting cervical lymph node metastasis of thyroid papillary carcinoma by Chang Liu, Chang Liu, Shangjie Yang, Shangjie Yang, Tian Xue, Qian Zhang, Qian Zhang, Yanjing Zhang, Yufang Zhao, Guolin Yin, Xiaohui Yan, Ping Liang, Liping Liu

“…The diagnostic performance of each model was evaluated and compared in terms of the area under the curve (AUC), sensitivity, specificity, accuracy, negative predictive value (NPV) and positive predictive value (PPV). …”
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Assessing and predicting the value of ecosystem services in Sanya City, Hainan Island, China by Peihong Song, Qiu Yang, Wenyin Wu, Tianyan Su, Yamin Jiang, Jingli Lu, Zhongyi Sun, Jie Zhang, Rui Yu, Peng Wang, Lan Wu, Huai Yang, Wenjie Liu

“…Factors influencing ESV and their interactions were analysed using convergent cross mapping (CCM) and global sensitivity and uncertainty analysis (GSUA). The results indicated that, from 2000 to 2020, forest, cultivated land and unutilized land areas decreased by 61.28 km2, 46.32 km2, and 1.91 km2, respectively, while water areas increased by 8.29 km2 and construction land expanded by 102.53 km2. …”
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Establishment of a Nomogram Model for Predicting Cardiovascular and Cerebrovascular Events in Diabetic Nephropathy Patients Receiving Maintenance Hemodialysis by Xiaobing Liu, Caili Yan, Xiuxiu Niu, Jiechun Zeng

“…Multivariate logistic regression analysis showed that age >60 years old, history of CCE, dialysis age >12 months, systolic blood pressure >140 mmHg, blood phosphorus level >1.5 mmol/L, triglyceride (TG) level >2.30 mmol/l, adiponectin (ADPN) level <5 mg/L, high-sensitivity-C-reactive protein (hs-CRP) level >10 mg/L, hemoglobin (Hb) level <120 g/L, serum creatinine (SCr) level >720 μmol/L, and albumin (ALB) level <40 g/L were independent risk factors for CCE. …”
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Adverse Effects of Intraparenchymal and Peritumoral Application of Isosulfan Blue Dye in Sentinel Lymph Node Mapping in Breast Cancer: A Systematic Review and Meta-Analysis by Joshua Agilinko, Aditya Borakati, Andrel Yoong, Ponnuthurai Pratheepan, Suzette Samlalsingh

“…Univariable meta-regression was performed to assess dose-response effect on adverse reactions. Sensitivity analysis was conducted using fixed effect modelling. …”
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Association between a body shape index and colorectal cancer in US population: a cross-sectional study based on NHANES by Hui Liu, Jialu Kang, Wei Liu, Yongqing Shen

“…Subgroup analysis indicated a notable interaction between age and BMI subgroups (interaction p &lt; 0.05), and ROC curves indicated that the ABSI was effective in predicting CRC risk (AUC = 0.658), demonstrating good sensitivity, particularly in individuals under 60 years of age.ConclusionA positive correlation exists between ABSI levels and the increased incidence of CRC among U.S. adults. …”
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