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26681
Integrating RNA-seq and scRNA-seq to explore the prognostic features and immune landscape of exosome-related genes in breast cancer metastasis
Published 2025-12-01“…Immune cell infiltration, immune escape and drug sensitivity disparities between high- and low-risk groups were assessed using CIBERSORT and single-sample gene set enrichment analysis (ssGSEA) methods. …”
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26682
Government Subsidy Decision-Making for Waste Tire Recycling under the Coexistence of the Retailer and the Internet Recycling Platform
Published 2022-01-01“…At the same time, this paper investigates the effects of government subsidies on social welfare and the profits of supply chain members under different scenarios and then verifies the optimal government subsidy decision with MATLAB software through numerical examples and sensitivity analysis. The results show that the government subsidy coefficient is positively correlated with social welfare under four subsidy scenarios. …”
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26683
Disrupting USP39 deubiquitinase function impairs the survival and migration of multiple myeloma cells through ZEB1 degradation
Published 2024-12-01“…The impact of USP39 knockdown via SiRNA was assessed through in vitro assays measuring cellular metabolism, clonogenic capacity, cell cycle progression, apoptosis, and sensitivity to BTZ. Co-immunoprecipitation and deubiquitination assays were conducted to elucidate the interaction and regulation of ZEB1 by USP39. …”
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26684
Effect of retaining wall leakage on the deformation behavior of foundation pit in water-rich sandy strata
Published 2025-01-01“…The ground settlement curve of behind the retaining wall successively transformed from “flat ladle bottom” shape, “shallow ladle bottom” shape to “deep ladle bottom” shape with excavation depth; the sensitive zone of settlement trough is 1.00he to 1.20he (he is excavation depth). …”
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26685
Importance of benzoyltransferase GcnE and lysine benzoylation of alcohol dehydrogenase AdhB in pathogenesis and aflatoxin production in Aspergillus flavus
Published 2025-01-01“…Both adhB deletion mutant and benzoylated site mutants (K321R and K321A) exhibited similar phenotype, including decreased conidiation and seed colonization, increased sclerotia formation and aflatoxin production, and more sensitive to cell wall damage stress. We also found that GcnE has benzoyltransferase activity in vitro and in vivo, and its repression leads to decreased Kbz level and enzymatic activity of AdhB. …”
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26686
Rapid Detection of microRNA-122 in Serum and Finger Blood Using a Lateral Flow Nucleic Acid Biosensor
Published 2025-01-01“…In this paper, we present a novel rapid testing method utilizing a lateral flow nucleic acid biosensor (LFNAB) for the sensitive and time-efficient detection of miR-122. …”
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26687
Cost-effectiveness of Catheter Ablation Versus Antiarrhythmic Drug Therapy for the Treatment of Atrial Fibrillation: A Canadian Perspective
Published 2016-10-01“…The 5-year probability of achieving cost-effectiveness was 0%, 0.9%, and 100% at the 3 cost per QALY thresholds. Results were most sensitive to time horizon, probability of repeat AF ablation, and stroke rate. …”
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26688
Process Optimization and Flavor Substance Analysis of Probiotic Fermented Apple Juice
Published 2025-01-01“…Electronic nose analysis demonstrated higher response values for the fermented apple juice across all sensors compared to the unfermented counterpart, indicating that probiotics could increase the content of aromatic volatile flavor substances in apple juice.…”
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26689
Metrological studies of the characteristics of multilayer surface coatings using synchrotron radiation
Published 2021-03-01“…At a photon energy of 40 ev, the absolute spectral sensitivity was 70 ma / W for a photodiode with a surface multilayer filter applied. …”
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26690
Comparative Lipid-Lowering/Increasing Efficacy of 7 Statins in Patients with Dyslipidemia, Cardiovascular Diseases, or Diabetes Mellitus: Systematic Review and Network Meta-Analyse...
Published 2020-01-01“…Then, subgroup analyses were conducted according to different baseline diseases. At last, sensitivity analyses were conducted according to age and follow-up duration. …”
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26691
Effect of Jin's Three-Needle Therapy Combined with Standing Digital OT Training on Upper Extremity Motor Function of Patients with Hemiplegia after Stroke
Published 2022-12-01“…The even reinforcing-reducing method was conducted, and when the patients brought about the desired sensation, the needle was retained for 30 minutes, once a day, six times a week, lasting for eight weeks. …”
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26692
Bladder mucosal smoothness predicts early recovery of urinary continence after laparoscopic radical prostatectomy
Published 2025-01-01“…The model achieved a highest area under the curve of 0.900 in the training set and the validation set. The sensitivity and specificity of the prediction model were 0.800 and 0.816. …”
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26693
The Effectiveness of Mindfulness-Based Stress Reduction Therapy on Disease signs and Symptoms and Psychological Distress in Women with Oral Lichen Planus
Published 2024-12-01“…The mean intensity of pain or burning sensation in the experimental group during the post-test phase was 2.94±1.85, compared to 3.65±1.69 in the control group; however, this difference was not statistically significant. …”
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26694
Winery By-Products In Vitro and In Vivo Effects on Atherothrombotic Markers: Focus on Platelet-Activating Factor
Published 2025-01-01“…Evidence from long-term studies shows that consumption may lower total and low density lipoprotein (LDL) cholesterol, improve insulin sensitivity, decrease lipid and protein oxidative damage, enhance antioxidant capacity, and have mild anti-inflammatory action toward reducing cytokine expression and levels. …”
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26695
A Framework for Early Detection of Acute Lymphoblastic Leukemia and Its Subtypes From Peripheral Blood Smear Images Using Deep Ensemble Learning Technique
Published 2024-01-01“…Experimental results are obtained and comparative analysis among 7 well-known CNN Network architectures (AlexNet, VGGNet, Inception, ResNet-50, ResNet-18, Inception and DenseNet-121) is also performed that demonstrated that the proposed platform achieved comparatively high accuracy (99.95%), precision (99.92%), recall (99.92%), F1-Score (99.90%), sensitivity (99.92%) and specificity (99.97%). …”
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26696
Cross-culturally adapted psychological interventions for the treatment of depression and/or anxiety among young people: A scoping review.
Published 2023-01-01“…Six studies used the ecological validity and cultural sensitivity framework. Planned adaptation, cultural adaptation of content, and surface and deep structure level adaptations were used in other studies. …”
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26697
Catholic Church Interiors in Fin-de-Siècle Literature
Published 2023-03-01“…Drawing on William Whyte’s analyses of changing attitudes towards church architecture in the 19th century in Unlocking the Church: The Lost Secrets of Victorian Sacred Space (OUP 2017), it shows how literary representations of church interiors in fin-de-siècle literature reflect the shift from the Protestant aniconic, congregation-centred approach to church design, in favour of an architecture of affect and sensation, where space and ornamentation lead the worshipper to experience the divine through a sensory overload. …”
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26698
Multi-scale channel attention U-Net: a novel framework for automated gallbladder segmentation in medical imaging
Published 2025-01-01“…Our proposed MCAU-Net model was employed for gallbladder segmentation and its performance was evaluated using Dice Similarity Coefficient (DSC), Jaccard Similarity Coefficient (JSC), Positive Predictive Value (PPV), Sensitivity (SE), Hausdorff Distance (HD), Relative Volume Difference (RVD), and Volumetric Overlap Error (VOE) metrics.ResultsOn the test set, MCAU-Net achieved DSC, JSC, PPV, SE, HD, RVD, and VOE values of 0.85 ± 0.22, 0.79 ± 0.23, 0.92 ± 0.14, 0.84 ± 0.23, 2.75 ± 0.98, 0.18 ± 0.48, and 0.22 ± 0.42, respectively. …”
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26699
Scaling Arctic landscape and permafrost features improves active layer depth modeling
Published 2025-01-01“…We showed that airborne sensors such as AVIRIS-NG and medium-resolution satellite Earth observation systems like Sentinel-2 can capture the average ALD at the landscape scale. …”
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26700
Predictive value of integrated pulmonary index for the outcome of ventilator withdrawal failure in elderly patients with hypoxic respiratory failure
Published 2025-01-01“…ROC curves showed that the AUC was 0.820 [95% CI: 0.719-0.920, P<0.001] , the sensitivity was 70.3%, the specificity was 82.6%, the maximum Youden index was 0.529, and the optimal cut-off value for IPI score was 4.77 scores. …”
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