Sepsis in Internal Medicine: blood culture-based subtypes, hospital outcomes, and predictive biomarkers by Gaetano Zizzo, Gabriele Guazzardi, Daniela Bompane, Francesco Di Terlizzi, Giorgio Rotola, Ilario Stefani, Michela Medugno, Mario Bucalo, Antonino Mazzone

“…Blood culture-negative sepses showed shorter stays and higher mortality (acute kidney injury and fast deterioration) compared to culture-positive ones; polymicrobial sepses showed higher ICU transfer rates (acute respiratory distress); while multidrug-resistant (MDR+) and/or polymicrobial sepses showed longer stays and higher mortality (complicated course) compared to drug-sensitive or monomicrobial ones. C-reactive protein elevation predicted rapidly evolving culture-negative sepsis, whereas lower leukocyte counts predicted prolonged hospitalization; higher fractions of inspired oxygen predicted polymicrobial sepsis, while lactate elevation predicted ICU transfer; ferritin elevation and increased leukocyte counts predicted MDR+ sepsis, while further ferritin elevation and decreased platelet counts predicted death. …”
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Direct high-precision radon quantification for interpreting high-frequency greenhouse gas measurements by D. Kikaj, E. Chung, A. D. Griffiths, S. D. Chambers, G. Forster, G. Forster, A. Wenger, P. Pickers, P. Pickers, C. Rennick, S. O'Doherty, J. Pitt, K. Stanley, D. Young, L. S. Fleming, L. S. Fleming, K. Adcock, E. Safi, T. Arnold, T. Arnold

“…Translating spot measurements of atmospheric GHG amount fractions into regional flux estimates (“top-down” analysis) is usually performed with atmospheric transport models (ATMs), which calculate the sensitivity of regional emissions to changes in observed GHGs at a finite number of locations. …”
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Assessment of Plasma Sodium to Potassium Ratio, Renal Function, Markers of Oxidative Stress, Inflammation, and Endothelial Dysfunction in Nigerian Hypertensive Patients by Oloruntoba A. Ekun, Folasade Daniel, Philip Adebola, Adeola Ajibare, Oyeronke O. Ekun, Oluwafunso O Omogoroye, Oluwafemi S. Ilori, Bankole J. Oluwasayo, Mary F. Oshundun, Sade R. Oyegbami

“…Glutathione, superoxide dismutase, nitric oxide (NO), and catalase were significantly reduced (p<0.001) while malondialdehyde (MDA), high-sensitivity C-reactive protein (hs-CRP), and ferritin were raised significantly (p<0.001) in hypertensive participants. …”
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Role of the Specialized Proresolving Mediator Resolvin D1 in Systemic Lupus Erythematosus: Preliminary Results by Luca Navarini, Tiziana Bisogno, Domenico Paolo Emanuele Margiotta, Alessandra Piccoli, Silvia Angeletti, Alice Laudisio, Massimo Ciccozzi, Antonella Afeltra, Mauro Maccarrone

“…The area under the ROC curve (AUC) for RvD1 was 0.71 (95% CI: 0.578–0.82) and the threshold value of RvD1 for the classification of SLE was <58.4 pg/ml, sensitivity 80% (95% CI: 61.4–92.3), and specificity 63.3% (95% CI: 43.9–80.1), likelihood ratio 2.2 (95% CI: 1.3–3.6). …”
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Machine learning-based prediction of hemodynamic parameters in left coronary artery bifurcation: A CFD approach by Sara Malek, Arshia Eskandari, Mahkame Sharbatdar

“…The ability to efficiently predict hemodynamic parameters could significantly aid medical practitioners in time-sensitive clinical settings, offering valuable insights for coronary artery disease management. …”
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Field Performance of Tissue Culture and Standard Propagated Raspberry Under Different Irrigation Regimes by Tatjana Anđelić, Jelena Tomić, Boris Rilak, Žaklina Karaklajić-Stajić, Jasminka Milivojević, Dragan Radivojević, Tatjana Vujović

“…In all experimental years, “Meeker” showed a high sweetness index (8.53, 11.28, and 9.36) due to high sugar and low acid content, but it was sensitive to water deficit. “Willamette” maintained high total anthocyanins and stable sugar content, which emphasizes its adaptability to different conditions. …”
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Impact of Covid-19 on Firm Performance: A Systematic Literature Review Using PRISMA Framework by Mahnoor Sattar, Rafayat Jalal

“…Future researchers may focus on conducting both short-term and long-term studies incorporating factors like government stimulus package, business sensitivity to multiple phases of Covid-19 and the country’s preparedness using longitudinal studies, surveys, meta-analysis, in-depth interviews, observations, and case studies to fully comprehend the effects of Covid-19.…”
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Neuropsychological outcome of indoor rehabilitation in post-COVID-19 condition—results of the PoCoRe study by Michael Jöbges, Melanie Tempfli, Melanie Tempfli, Christoph Kohl, Christoph Herrmann, Stefan Kelm, Alexa Kupferschmitt, Alexa Kupferschmitt, Alexa Kupferschmitt, Ida Montanari, Nike Walter, Gerhard Suetfels, Thomas Loew, Volker Köllner, Volker Köllner, Thilo Hinterberger

“…However, the MoCA demonstrated limited sensitivity in detecting attention deficits.ConclusionThe PoCoRe study highlights the high prevalence of neuropsychological deficits and fatigue in PCC patients, with notable improvements observed following multidisciplinary rehabilitation. …”
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Eye health risks associated with unclean fuel: a meta-analysis and systematic review by Shi-Hang Chen, Yuan Tang, Song Xue, Song Xue

“…Heterogeneity among articles was gaged with the I2 statistic, sensitivity analysis used ‘leave-one-out test’, and publication bias was evaluated using Egger, Begg tests, and funnel plot analysis.ResultsThe study evidenced a significant association between UCF exposure and cataracts [OR 2.29, 95% CI (1.24, 4.23)], visual impairments [OR 1.70, 95% CI (1.45, 2.00)], and eye diseases/symptoms [OR 2.03, 95% CI (1.25, 3.29)]. …”
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Multidimensional Plasma Lipids Affect Preeclampsia/Eclampsia: A Mendelian Randomization Study by Shaole Shi, Fangyuan Wu, Shanshan Zhao, Zilian Wang, Yongqiang Fan

“…Summary statistics from plasma lipidomics of 7174 Finnish individuals and summary data on preeclampsia/eclampsia from the FinnGen consortium involving 219 817 European participants were employed. Sensitivity analyses were conducted to evaluate heterogeneity and pleiotropy. …”
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Enhancing individual glomerular filtration rate assessment: can we trust the equation? Development and validation of machine learning models to assess the trustworthiness of estima... by Antoine Lanot, Anna Akesson, Felipe Kenji Nakano, Celine Vens, Jonas Björk, Ulf Nyman, Anders Grubb, Per-Ola Sundin, Björn O. Eriksen, Toralf Melsom, Andrew D. Rule, Ulla Berg, Karin Littmann, Kajsa Åsling-Monemi, Magnus Hansson, Anders Larsson, Marie Courbebaisse, Laurence Dubourg, Lionel Couzi, Francois Gaillard, Cyril Garrouste, Lola Jacquemont, Nassim Kamar, Christophe Legendre, Lionel Rostaing, Natalie Ebert, Elke Schaeffner, Arend Bökenkamp, Christophe Mariat, Hans Pottel, Pierre Delanaye

“…In the external validation cohort, the model achieved an area under the curve of 0.675 (95%CI 0.660;0.690) and an accuracy of 0.716 (95%CI 0.707;0.725) for the P30 criterion. Sensitivity was 0.756 (95%CI 0.747;0.765) and specificity was 0.485 (95%CI 0.460; 0.511) at the 80% probability level that EKFC falls within 30% of mGFR. …”
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AI-assisted detection for chest X-rays (AID-CXR): a multi-reader multi-case study protocol by Fergus Gleeson, Alex Novak, Indrajeet Das, Ruchir Shah, Edwin van Beek, Sarim Ather, Howell Fu, Nabeeha Salik, Alan Campbell, Farhaan Khan, Abdala Trinidad Espinosa Morgado, Marusa Kotnik, Louise Wing, John Murchison, Jong Seok Ahn, Sang Hyup Lee, Ambika Seth

“…Performance testing will be carried out with readers from various clinical professional groups with and without the assistance of Lunit INSIGHT CXR to evaluate the utility of the algorithm in improving reader accuracy (sensitivity, specificity, AUROC), confidence and speed (paired sample t-test). …”
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An Optimized Liquid Chromatography–Mass Spectrometry Method for Ganglioside Analysis in Cell Lines by Akeem Sanni, Andrew I. Bennett, Yifan Huang, Isabella Gidi, Moyinoluwa Adeniyi, Judith Nwaiwu, Min H. Kang, Michelle E. Keyel, ChongFeng Gao, C. Patrick Reynolds, Brian Haab, Yehia Mechref

“…These results suggest that our method provides a sensitive, reliable, and high-throughput workflow for ganglioside profiling across different cell types.…”
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ANALYSIS OF AIR QUALITY IN TELEORMAN BY MEANS OF BIOMONITORS-LICHENS by Cernat POPA

“…These organisms are sensitive to heavy metal pollution and can accumulate significant amounts of metals in their tissues. …”
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Evaluation of Competency-Based Medical Education (CBME) curriculum implementation for Phase II Medical undergraduates: A qualitative study by KRISHNAMURTHY SOUNDARIYA, ANANDABASKAR NISHANTHI, RAJALAKSHMI MAHENDRAN, MOUROUGUESSINE VIMAL

“…Addressing these challenges requires careful planning and evaluation, with faculty sensitization being crucial for smooth implementation. …”
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Comparative Pharmacokinetic Study of Three Major Bioactive Components in the Normal and Different Courses of Liver-Stagnation and Spleen-Deficiency Syndrome Depressive Rats after I... by Kaiwen Luo, Mengdie Wang, Xiangxiang Pan, Yadong Xing

“…The UHPLC-MS/MS method was stabilized, sensitive, and exclusive, and the extraction recovery and matrix effect of three analytes were all above 89%. …”
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Hsp70/Bmi1-FoxO1-SOD Signaling Pathway Contributes to the Protective Effect of Sound Conditioning against Acute Acoustic Trauma in a Rat Model by Guoxia Zhu, Yongxiang Wu, Yang Qiu, Keyong Tian, Wenjuan Mi, Xinqin Liu, Yuanyuan Chen, Jinwen Jia, Jiasheng Luo, Lianjun Lu, Jianhua Qiu

“…Collectively, these results suggested that the contribution of Bmi1 toward decreased sensitivity to noise-induced trauma following SC was triggered by Hsp70 induction and associated with enhancement of the antioxidant system and decreased mitochondrial superoxide accumulation. …”
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The impact of self-care training using the teach-back method on health anxiety in patients with coronary artery disease: A randomized controlled clinical trial by Mansoreh Barati, Zahra Amouzeshi, Fahimeh Nikraftar

“…The results indicated that there was a statistically significant difference in the total mean score (P = 0.000) and mean scores of subscales of health anxiety (awareness of bodily sensations or changes (P = 0.001), feared consequences of having an illness (P = 0.001), and worry about health (P = 0.008)) between the two groups. …”
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Polysulfide and persulfide-mediated activation of the PERK-eIF2α-ATF4 pathway increases Sestrin2 expression and reduces methylglyoxal toxicity by Shin Koike, Hideo Kimura, Yuki Ogasawara

“…Unfolded protein response (UPR) is activated in cells under endoplasmic reticulum (ER) stress. One sensor protein involved in this response is PERK, which is activated through its redox-dependent oligomerization. …”
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Quantification of key factors and hazard classification of “coal wall” stability under high-intensity mining by Shaohong YAN, Bo XUE

“…Numerical simulation and physical similarity experiments were used to study the sensitivity of various mining technology factors to the stability of the coal wall. …”
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