Differential GTP-dependent in-vitro polymerization of recombinant Physcomitrella FtsZ proteins by Stella W. L. Milferstaedt, Marie Joest, Lennard L. Bohlender, Sebastian N. W. Hoernstein, Buğra Özdemir, Eva L. Decker, Chris van der Does, Ralf Reski

“…Abstract Bacterial cell division and plant chloroplast division require selfassembling Filamentous temperature-sensitive Z (FtsZ) proteins. FtsZ proteins are GTPases sharing structural and biochemical similarities with eukaryotic tubulin. …”
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Discriminant analysis of occupational performance characteristics in patients with major depressive disorders and healthy individuals by Tomonari Hayasaka, Izumi Nagashima, Miku Hoshino, Koji Teruya, Yasuyuki Matumoto, Masami Murao, Taku Maruki, Masako Watanabe, Takeshi Katagiri, Yayoi Imamura, Mariko Kurihara, Yuki Oe, Yoshikazu Takaesu, Takashi Tsuboi, Koichiro Watanabe, Hitoshi Sakurai

“…The receiver operating characteristic curve's AUC value was 0.911 (sensitivity = 95.3%, specificity = 77.8%). Conclusion This study highlights the importance of occupational performance characteristics in tailoring treatment strategies for MDD, providing insights beyond traditional assessment methods.…”
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Predictive accuracy of lactate albumin ratio for mortality in intensive care units: a nationwide cohort study by Yohei Okada, Yoshitaka Aoki, Mikio Nakajima, Yasuhito Suzuki, Mikihiro Shimizu, Ryo Imai, Soichiro Mimuro, Yoshiki Nakajima

“…LAR shape was assessed using unrestricted spline curves, and the optimal cut-off value was identified from sensitivity and negative likelihood ratio. Subgroup analysis was used to evaluate the predictive accuracy of the LAR across different patient attributes and clinical scenarios.Results Of 2 34 774 cases analysed, in-hospital mortality was 8.8% (20 723 deaths). …”
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Systematic review and bayesian network meta-analysis: comparative efficacy and safety of six commonly used biologic therapies for moderate-to-severe Crohn’s disease by Haohang Su, Haohang Su, Shengwei Xiao, Zhiqing Liang, Zhiqing Liang, Tianrong Xun, Jinfang Zhang, Jinfang Zhang, Xixiao Yang, Xixiao Yang

“…Finally, we completed sensitivity and consistency analyses, and evaluated the certainty of evidence through GRADE working group guidance.ResultsWe identified 22 and 20 RCTs for induction and maintenance therapy, respectively. …”
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Characterization of Mice Ubiquitously Overexpressing Human 15-Lipoxygenase-1: Effect of Diabetes on Peripheral Neuropathy and Treatment with Menhaden Oil by Lawrence Coppey, Alexander Obrosov, Hanna Shevalye, Eric Davidson, William Paradee, Mark A. Yorek

“…Wild-type and transgenic diabetic mice developed DPN as determined by slowing of nerve conduction velocity, decreased sensory nerve fibers in the skin and cornea, and impairment of thermal and mechanical sensitivity of the hindpaw compared to their respective control mice. …”
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A Simplified, Specific HPLC Method of Assaying Thiamine and Riboflavin in Mushrooms by Mohammad F. Hossain, Mamoon Rashid, Rajjit Sidhu, Randy Mullins, Susan L. Mayhew

“…The proposed method was found to be specific, linear R>1.0, accurate, precise (% recovery ± SD; B1:104.45±4.5 and B2: 104.88±2.04), sensitive, (limit of detection for B1 and B2 was 0.043 and 0.029 μg/mL, respectively), and robust for mushrooms analysis. …”
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The privacy protection of the internet of vehicles resource transaction details based on blockchain. by Jing Chen, Tao Li, Min Huang

“…The scheme realized the comprehensive privacy protection of transaction funds, transaction details and transaction addresses, which could effectively avoid the disclosure of users' sensitive information. Compared with the existing methods, the proposed scheme not only greatly enhanced the privacy protection capability, but also ensured the efficiency and security of transaction verification through zero-knowledge proof, avoiding the direct exposure of private keys. …”
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Expression and clinical significance of disulfidptosis-related LncRNA in gastric cancer by CHU Yudan, SUN Haidong, CUI Ran, ZHENG Hong

“…DRG-RS model was significantly correlated with tumor-related signaling pathways, clinical characteristics and drug sensitivity of gastric cancer patients. LncRNA-SNHG4 expression was significantly increased in gastric cancer. …”
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Climate Change and Environmental Influence on Prevalence of Visceral Leishmaniasis in West Pokot County, Kenya by Bulle Abdullahi, Joshua Mutiso, Fredrick Maloba, John Macharia, Mark Riongoita, Michael Gicheru

“…Climate change-induced seasonal weather variability, increased temperature and reduced precipitation as well as environmental alterations influence kala-azar occurrence in West Pokot. Community sensitization on disease prevalence, clearing of vector predilection sites, and improving community environmental risk perception are imperative to promote prevention.…”
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Visceral adipose tissue area and proportion provide distinct reflections of cardiometabolic outcomes in weight loss; pooled analysis of MRI-assessed CENTRAL and DIRECT PLUS dietary... by Hadar Klein, Hila Zelicha, Anat Yaskolka Meir, Ehud Rinott, Gal Tsaban, Alon Kaplan, Yoash Chassidim, Yftach Gepner, Matthias Blüher, Uta Ceglarek, Berend Isermann, Michael Stumvoll, Ilan Shelef, Lu Qi, Jun Li, Frank B. Hu, Meir J. Stampfer, Iris Shai

“…Conversely, higher VATcm2 was associated with elevated high-sensitivity C-reactive protein (hsCRP), while VAT% was not. …”
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Understanding the unique role of community-based para-professionals delivering early childhood development in low-resource contexts: a Delphi study by Emma Claire Pearson, Maxwell Peprah Opoku

“…Conclusion The findings provide a basis for supporting and strengthening this important workforce, through advocacy around (i) their unique contributions in supporting contextually-sensitive, responsive ECD, (ii) training approaches and strategies that support and build on these contributions, and (iii) mechanisms to support stronger recognition through career pathways and training needs that are shared with other ECD cadre groups (including health and education professionals).…”
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Both Low and High Postprocedural hsCRP Associate with Increased Risk of Death in Acute Coronary Syndrome Patients Treated by Percutaneous Coronary Intervention by Runzhen Chen, Chen Liu, Peng Zhou, Yu Tan, Zhaoxue Sheng, Jiannan Li, Jinying Zhou, Yi Chen, Li Song, Hanjun Zhao, Hongbing Yan

“…Inflammation poses dual effects after myocardial infarction, but robust evidence shows that high-sensitivity C-reactive protein (hsCRP), as an inflammatory marker, is constantly associated with worse outcomes. …”
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An EEG-based framework for automated discrimination of conversion to Alzheimer’s disease in patients with amnestic mild cognitive impairment: an 18-month longitudinal study by Yingfeng Ge, Jianan Yin, Caie Chen, Shuo Yang, Yuduan Han, Chonglong Ding, Jiaming Zheng, Yifan Zheng, Jinxin Zhang

“…The performance of each model was assessed using 10-fold cross-validation and evaluated in terms of accuracy (ACC), area under the curve (AUC), sensitivity (SEN), specificity (SPE), positive predictive value (PPV), and F1-score.ResultsCompared to SMCI patients, PMCI patients exhibit a trend of “high to low” frequency shift, decreased complexity, and a disconnection phenomenon in EEG signals. …”
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Numerical modelling of rope elasticity for heave compensation lifting in offshore crane operations by Bassey Asanga, Akanimo Ekpenyong, Aniekan Ikpe

“…Real time data were collected using classy equipment / sensors. First, a mathematical model for wire rope extension was developed using Newton / Euler’s approach when heave compensation system (HCS) was turned off (WOC) and validated using associated wire rope physical properties. …”
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Spatiotemporal characteristics of macroinvertebrate functional feeding groups and biological assessment of water quality in the Hulan River Basin by Peilun Li, Shuhan Xiong, Jiacheng Liu, Xiangsheng Meng, Anqi Wang, Chunfeng Wang, Yanshen Zhang, Jilong Wang

“…This study demonstrates that macroinvertebrate FFGs are highly sensitive to human activities and agricultural pollution in the midstream and downstream areas of the Hulan River Basin. …”
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Integrative multi-omics analysis reveals the role of toll-like receptor signaling in pancreatic cancer by Jie Peng, Jiaao Sun, Youfeng Yu, Qihang Yuan, Yong Zhang

“…By calculating the TLR pathway score, we clustered pancreatic cancer patients and conducted a series of analyses including metabolic pathways, immune microenvironment, drug sensitivity and so on. In the process of building prognostic models, we screened 33 core genes related to the prognosis of pancreatic cancer, and combined a series of machine learning algorithms to build the prognosis model of pancreatic cancer. …”
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Continuous atrial fibrillation monitoring using a wearable smartwatch: Using long-term Holter as reference by Yannan Pan, Erdong Chen, Shihui Jie, Dongbo Huo, Zhongru Ding, Jing Zhou, Jie Jiang, Jianping Li, Yong Huo

“…Smartwatch recording time was 8927.6 hours. By individual, sensitivities and specificities of AF longer than 5 minutes were 100.0% and 83.7% for PPG and 89.7% and 67.4% for the ECG algorithm. …”
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Association of player position and functional connectivity alterations in collegiate American football players: an fMRI study by Owen Griffith, Xiaoxiao Bai, Alexa E. Walter, Michael Gay, Jon Kelly, Wayne Sebastianelli, Linda Papa, Semyon Slobounov

“…IntroductionResting state-fMRI, provides a sensitive method for detecting changes in brain functional integrity, both with respect to regional oxygenated blood flow and whole network connectivity. …”
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Regional Arterial Stiffness in Patients with Inflammatory Bowel Disease by V. V. Genkel, R. G. Portnova, T. V. Antipina, I. I. Shaposhnik

“…The laboratory research plan included the analysis of complete blood count, biochemical parameters, fibrinogen and a high sensitivity  C-reactive protein (hsCRP).Results. crPWV, similar to cfPWV, was not significantly different between the groups. …”
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Ability of pulse oximetry-derived indices to predict hypotension after spinal anesthesia for cesarean delivery: A systematic review and meta-analysis. by Yuriko Kondo, Eishin Nakamura, Hisashi Noma, Sayuri Shimizu, Takahisa Goto, Takahiro Mihara

“…Of the 19 studies, involving 1437 patients, 17 assessed the PI in 1,311 patients, and 5 assessed the PVI in 344 patients. The summary sensitivity and specificity of the PI were 0.75 (95% confidence interval [CI]: 0.69-0.80) and 0.64 (95%CI: 0.48-0.77), respectively, while those of the PVI were 0.63 (95%CI: 0.47-0.76) and 0.76 (95%CI: 0.64-0.84), respectively. …”
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