Detection of BRAF V600E in Fine-Needle Aspiration Samples of Thyroid Nodules by Droplet Digital PCR by Sang-Yu Lu, Ying-Chao Chen, Jia-Lin Feng, Qin-Yi Zhou, Jing Chen, Chen-Fang Zhu, Miao-Miao Guo, Man-Man Zhang, Qian-Yue Zhang, Meng Lu, Liu Yang, Jing Wu, Shuang-Xia Zhao, Huai-Dong Song, Xiao-Ping Ye

“…Conclusion. ddPCR has higher sensitivity than Sanger sequencing and we propose ddPCR as a supplement to Sanger sequencing in molecular testing of BRAF using FNAB samples.…”
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EVALUATION OF THE APPLICABILITY OF THE O.K.N.V.I. RESIST-5 AND THE KPC&MBL&0XA-48 DISK TESTS IN A ROUTINE MICROBIOLOGY LABORATORY by Stefana Sabtcheva, Sylvia Georgieva

“…It is easy to handle and provides results with 100% sensitivity and specificity when an inoculum around ertapenem disc from routine antibiogram was used. …”
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Effect of Bovine Serum Albumin (BSA) Concentration on Cryopreservation of Booroolong Frog Sperm with Evaluation of Post-Thaw Motility in Caffeine by Zara M. Anastas, Aimee J. Silla, Phillip G. Byrne, Rebecca J. Hobbs, Michael S. McFadden, Jonathan Daly, Justine K. O’Brien

“…The results reported herein provide no evidence for an effect of BSA or caffeine at the concentrations tested on post-thaw sperm characteristics in the Booroolong frog, but they highlight the time-sensitive nature of sperm assessment post-thaw and implications for the timing of sperm handling during assisted fertilisation efforts.…”
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Optimal multiobjective design of an autonomous hybrid renewable energy system in the Adrar Region, Algeria by Abderrahmane Mehallou, Benalia M’hamdi, Abderrahmane Amari, Madjid Teguar, Abdelaziz Rabehi, Mawloud Guermoui, Amal H. Alharbi, El-Sayed M. El-kenawy, Doaa Sami Khafaga

“…The findings reveal that the MOPSO method has the most efficient hybrid renewable configuration with an annual generation cost of electricity (COE) of 0.2520 $/kWh and loss of power supply probability (LPSP) of 9.164%, which dominates the performance of MOALO (COE of 0.1625$/kWh and LPSP of 8.4872%), MOGA (COE of 0.1577$/kWh and LPSP of 10%), and MODA (COE of 0.02425$/kWh and LPSP of 7.8649%). Furthermore, a sensitivity analysis is performed for the effect that COE variants may have on the design variables.…”
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Rehabilitation diagnosis of patients with mine-explosive wounds of the lower leg based on the international classification of functioning, disability and health by O.E. Dorofieieva, K.S. Yarymbash, O.A. Glinyana, Yu.V. Syomych, I.T. Skrypchenko

“…In the course of the clinical and instrumental methods of examination of patients with mine-explosive wounds at the level of the lower leg, the assessment of categories according to the ICF revealed disorders at the level of structure: functions: s 75010 bones of lower leg, s 75012 muscles of lower leg, s 75013 ligaments and fasciae of lower leg, s 8104 skin of lower extremity; b 28015 pain in the lower limb, b 4550 general physical endurance, b 7101 mobility of several joints, b 7351 muscle tone of one limb, b 770 function of the stereotype of walking, b 7800 sensation of muscular stiffness, b 810 protective function of skin; activities: d 4104 standing position, d 4106 moving the center of gravity of the body, d 4501 walking long distances, d 465 moving using technical means, d 5100 washing body parts, d 5102 wiping and drying, d 5402 putting on footwear, d 5403 taking off footwear, d 5702 self-health support, d 850 well-paid work, d 920 recreation and leisure, e 1151 assistive products and technologies for personal everyday use, e 310 close relatives, e 355 professional health care workers. …”
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‘It was just the given thing to do’: exploring enablers for high childhood vaccination uptake in East London’s Bangladeshi community—a qualitative study by Sadie Bell, Sandra Mounier-Jack, Ifra Ali

“…Our findings suggest culturally sensitive, person-centred delivery of vaccination services, alongside leveraging community dynamics and trusted social networks, are imperative to meeting the informational, linguistic and cultural needs that facilitate vaccine uptake within the Bangaldeshi community. …”
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The Role of Endogenous Beta-Endorphin and Enkephalins in the Crosstalk Between Ethanol and Morphine by Andy Tseng, Syed Muzzammil Ahmad, Abdul Hamid, Kabirullah Lutfy

“…Thus, we hypothesized that ethanol, by causing the release of opioid peptides, may sensitize the system to the action of exogenous opioids such as morphine. …”
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Genome-wide transcriptome analysis and drug target discovery reveal key genes and pathways in thyroid cancer metastasis by Minjing Zou, Amal Qattan, Monther Al-Alwan, Hazem Ghebeh, Naif Binjumah, Latifa Al-Haj, Khalid S. A. Khabar, Abdulmohsen Altaweel, Falah Almohanna, Abdullah M. Assiri, Abdelilah Aboussekhra, Ali S. Alzahrani, Ali S. Alzahrani, Yufei Shi

“…Braf-mutant Met cells developed resistance to BRAFV600E inhibitor PLX4720, but remained sensitive to β-catenin inhibitor PKF118-310.ConclusionWe have identified several overexpressed genes/pathways in thyroid cancer metastasis, making them attractive therapeutic targets. …”
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The Relationship between Statin and Risk of Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis by Ezatollah Memarzadeh, Saeid Heidari-Soureshjani

“…Subgroup analyses and sensitivity analyses were also conducted. Cochran’s Q test and the I2 statistic were used to evaluate the heterogeneity. …”
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Diagnostic efficacy and necessity of 18F-FDG PET/CT in fever of unknown origin: insights from a retrospective cohort study by Xiaoman Yu, Shuang Wang, Na Du, Hongguang Zhao, Haiying Chen

“…The final diagnoses of 136 patients (47.9%) correlated with their 18F-FDG PET/CT results, yielding a sensitivity of 79.5%, specificity of 61.1%, positive predictive value of 75.6%, and negative predictive value of 66.3%. …”
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The Naples Score: Can it Outperform Existing Scores in Predicting Gastric Cancer Mortality? by Bahadır Kartal, Mehmet Berksun Tutan, Fatih Şahin, Ertugrul Gazi Alkurt

“…The Prognostic Nutritional Index had the highest predictive accuracy with an Area Under the curve of 0.792, a sensitivity of 76%, and a specificity of 86.2%, outperforming the others. …”
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Bidirectional causal associations between frailty measures and sleep disturbances: a two-sample Mendelian randomization study by Che L, Zang H, Bi Y, Wen B, Xu L

“…We conducted the causal estimates using the inverse variance-weighted method (IVW), with sensitivity analyses using MR-Egger, weighted median, weighted mode, and MR pleiotropy residual sum and outlier (MR-PRESSO) analysis. …”
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Prevalence of dengue and leptospirosis coinfection and associated mortality rates: a systematic review and meta-analysis by Suraj Tiwari, Mahalaqua Nazli Khatib, Rekha MM, Mandeep Kaur, Girish Chandra Sharma, Puneet Sudan, K. Satyam Naidu, Rajesh Singh, Teena Vishwakarma, Sonam Puri, Muhammed Shabil, Anuradha Yadav, Takveer Singh, Sahil Khurana, Rachana Mehta, Prakasini Satapathy, Renu Sah, Abhay M Gaidhane, Ganesh Bushi

“…Statistical analyses, including prevalence and mortality estimation, sensitivity analysis were conducted using R, with heterogeneity evaluated by the I² statistic. …”
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Optimization of cross-sectional shape and support parameters of headgate in fully mechanized coal seam with large dip angle and close distance by Kun PAN, Wenjun JU, Junchao WANG, Housheng JIA, Biao HOU, Yinwei WANG, Zhiming ZHANG

“…The research results indicate that under the conditions of intense mining of steeply inclined coal seams, regardless of how the roadway cross-section changes, the form of surrounding rock failure always exhibits the maximum depth of failure towards the roof, and due to the strong stress sensitivity of the plastic zone near the upper working face area, the range and depth of the plastic zone reach a maximum, However, there are significant differences in the overall failure patterns and distribution ranges of the plastic zone among the three cross-sectional shapes. …”
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Association between prostate-specific antigen density and prostate cancer prediction among Nigerian men by Abudu EK, Okuku CN, Akaiso OE, Fabian UA, Udoh EA, Ukpong AE, Kudamnya IJ, Ajayi OO, Uduma FU, Abudu OO, Ekpo BO

“…PSAD showed statistical significance in cancer detection (p < 0.001) with a detection rate, sensitivity and false positive rate of 90.0 %, 85.0 % and 8.0 % respectively. …”
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High Body Roundness Index Is Associated With Unhealthy Sleep Patterns: Insights From NHANES (2007–2014) by Pingchuan Liu, Yuding Luo, Xing He, Jiali Zhang, Fanzhou Ren, Bingyang Zhang, Bo Zheng, Jian Wang

“…The RCS analysis found that the nonlinear association between BRI and unhealthy sleep patterns was not significant. Subgroup and sensitivity analyses indicated a consistently positive association between high BRI and unhealthy sleep patterns across most subgroups. …”
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In-hospital mortality among neonates with necrotising enterocolitis in Ethiopia: a systematic review and meta-analysis by Addisu Getie, Adam Wondmieneh, Melaku Bimerew, Manay Ayalneh, Freweyni Gebreegziabher Araya, Nigatu Dessalegn

“…Test of heterogeneity, publication bias, sensitivity analysis, subgroup analysis and meta-regression were performed.Results A total of 12 articles involving 588 neonates were included. …”
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Cerebral 18F-FDG PET in macrophagic myofasciitis: An individual SVM-based approach. by Paul Blanc-Durand, Axel Van Der Gucht, Eric Guedj, Mukedaisi Abulizi, Mehdi Aoun-Sebaiti, Lionel Lerman, Antoine Verger, François-Jérôme Authier, Emmanuel Itti

“…To evaluate the performance of the SVM classifier, values of sensitivity (Se), specificity (Sp), positive predictive value (PPV), negative predictive value (NPV) and accuracy (Acc) were calculated.…”
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Моделі самоорганізації колективу однорідних безпілотних літальних апаратів при рішенні слабоформалізованих завдань... by А.В. Тристан, Д.І. Жуков

“… The development and modernization of unmanned aerial vehicles (UAVs), their control systems, safety and regulation, expansion of functionality, miniaturization and increase of sensor performance, improvement of energy capabilities and routing process, increase of autonomy, contributes to the improvement of the performance of tasks. …”
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Visfatin Related to the Severity of Non-ST-Segment Elevation Acute Coronary Syndrome: A Retrospective Study of 164 Patients at a Tertiary Chest Pain Center by Meifan Zheng, Zhongwei Wu, Chaoquan Liu, Fei Xiao

“…Receiver-operating characteristic (ROC) curves demonstrated enhanced prognostic ability when combining visfatin with age, hypertension, and diabetes for multivessel disease (AUC: 0.839, sensitivity: 65.0%, specificity: 89.7%, P<0.001). Elevated serum visfatin in NSTE-ACS patients suggests its role as an independent harbinger for the number of affected coronary arteries, potentially indicating severity in NSTE-ACS patients.…”
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