Screening and Functional Pathway Analysis of Pulmonary Genes Associated with Suppression of Allergic Airway Inflammation by Adipose Stem Cell-Derived Extracellular Vesicles by Sung-Dong Kim, Shin Ae Kang, Yong-Wan Kim, Hak Sun Yu, Kyu-Sup Cho, Hwan-Jung Roh

“…Methods. C57BL/6 mice were sensitized to ovalbumin (OVA) by intraperitoneal injection and challenged intranasally with OVA. …”
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Acetaminophen administration reduces acute kidney injury risk in critically ill patients with Clostridium difficile infection: A cohort study. by Yue Liao, Yulong Wang, Daxue Li, Xuewen Qiu

“…Additionally, subgroup analyses and sensitivity analysis were conducted to assess the robustness of our primary findings.…”
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The role of mNGS in the diagnosis of talaromycosis and case series by Jing Zhao, Hui-Ting Su, Dong Zhang, Xue-Tong Li, Min-Ya Lu, Juan Du, Jia-Yu Guo, Yi Gao, Xin-Fei Chen, Dong-Hua Wen, Shi-Yu Jia, Yao Wang, Qi-Wen Yang

“…Conclusions Traditional diagnostic methods are limited by factors such as the long time and low sensitivity of fungal culture, the effect of prior antibiotic treatment, the invasiveness and complexities of tissue biopsies, and so on. …”
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HOTSSea v1: a NEMO-based physical Hindcast of the Salish Sea (1980–2018) supporting ecosystem model development by G. Oldford, G. Oldford, T. Jarníková, V. Christensen, M. Dunphy

“…We used an experimental approach to incrementally assess sensitivity to atmospheric and ocean reanalysis products used for boundary forcings and to the horizontal discretisation of the model grid (<span class="inline-formula">∼</span> 1.5 km). …”
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Risk prediction tools for pressure injury occurrence: an umbrella review of systematic reviews reporting model development and validation methods by Bethany Hillier, Katie Scandrett, April Coombe, Tina Hernandez-Boussard, Ewout Steyerberg, Yemisi Takwoingi, Vladica Velickovic, Jacqueline Dinnes

“…Five reviews presented measures of discrimination, such as the area under the curve (AUC), sensitivities, specificities, F1 scores, and G-means. …”
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Diagnostic utility of translabial ultrasound in pelvic organ prolapse: a prospective observational study by Milosz Pietrus, Kazimierz Pityński, Iwona Gawron, Maciej W. Socha, Krzysztof Nowosielski, Robert Biskupski-Brawura-Samaha, Marcin Waligóra

“…Among the respondents, 55.9% reported experiencing the sensation of POP. Mean POP levels determined using the two approaches precisely matched in 46.5% of these cases. …”
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Advancements in noninvasive techniques for transplant rejection: from biomarker detection to molecular imaging by Yuan Song, Yihui Wang, Wenyuan Wang, Yuji Xie, Junmin Zhang, Jing Liu, Qiaofeng Jin, Wenqian Wu, He Li, Jing Wang, Li Zhang, Yali Yang, Tang Gao, Mingxing Xie

“…For example, donor-derived cell-free DNA (dd-cfDNA) is highly sensitive in detecting early graft injury, whereas gene expression profiling effectively excludes moderate-to-severe acute rejection (AR). …”
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Excess ventilation and chemosensitivity in patients with inefficient ventilation and chronic coronary syndrome or heart failure: a case–control study by Prisca Eser, Dominic Käesermann, Pietro Calamai, Anja Kalberer, Laura Stütz, Sarina Huber, James Duffin, Matthias Wilhelm

“…The Duffin rebreathing method was used to determine the resting end-expiratory partial pressure of carbon dioxide (PETCO2), ventilatory recruitment threshold (VRT), and slope (sensitivity) during a hyperoxic (150 mmHg O2) and hypoxic (50 mmHg O2) rebreathing test to determine the central and peripheral chemosensitivity.ResultsIn patients with CCS, HF, controls, and young healthy adults, median V̇E/V̇CO2 slopes were 40.2, 41.3, 30.5, and 28.0, respectively. …”
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Does Daily Physical Activity Differ Between Patients with Femoroacetabular Impingement Syndrome and Patients with Hip Dysplasia? A Cross-Sectional Study in 157 Patients and 60 Heal... by Lisa C. U. Reimer, Signe Kierkegaard, Inger Mechlenburg, Julie S. Jacobsen

“… # Methods PA was measured with accelerometer-based sensors, and sport/recreation was measured with the Copenhagen Hip and Groin Outcome Score (HAGOS). …”
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Rate of cesarean section among breech deliveries in Ethiopia: a systematic review and meta-analysis by Ibsa Mussa, Adera Debella, Lemma Demissie Regassa, Badhasa Ahamed, Usmael Jibro, Addis Eyeberu

“…The overall effect size with a 95% CI was estimated using the random effect model with the Der Simonian Liard method. A sensitivity analysis using a leave-one-out meta-analysis was computed.ResultsThis meta-analysis included a total of 57,236 mothers who had breech deliveries. …”
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Normalization of tumor vasculature by imiquimod: proposal for a new anticancer therapeutic indication for a TLR7 agonist by Jarosz-Biej Magdalena, Czapla Justyna, Ciepła Joanna, Smolarczyk Ryszard, Drzyzga Alina, Sprus-Lipka Dorota, Pilny Ewelina, Matuszczak Sybilla, Cichoń Tomasz

“…It acts as an immunostimulant and radio-sensitizing agent. IMQ stimulates both innate and adaptive immune response. …”
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Advancing presurgical non-invasive spread through air spaces prediction in clinical stage IA lung adenocarcinoma using artificial intelligence and CT signatures by Guanchao Ye, Guangyao Wu, Yiying Li, Chi Zhang, Lili Qin, Lili Qin, Jianlin Wu, Jun Fan, Yu Qi, Fan Yang, Yongde Liao

“…The models' performance was evaluated using metrics such as the area under the receiver operating characteristic curve (AUC), negative predictive value (NPV), positive predictive value (PPV), sensitivity, specificity, calibration curve, and decision curve analysis (DCA).ResultsIn the training cohort, the clinical model achieved an AUC value of 0.775, the radiomics model achieved an AUC value of 0.836, and the combined model achieved an AUC value of 0.837. …”
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The MBH–M∗ Relation up to z ∼ 2 through Decomposition of COSMOS-Web NIRCam Images by Takumi S. Tanaka, John D. Silverman, Xuheng Ding, Knud Jahnke, Benny Trakhtenbrot, Erini Lambrides, Masafusa Onoue, Irham Taufik Andika, Angela Bongiorno, Andreas L. Faisst, Steven Gillman, Christopher C. Hayward, Michaela Hirschmann, Anton Koekemoer, Vasily Kokorev, Zhaoxuan Liu, Georgios E. Magdis, Alvio Renzini, Caitlin Casey, Nicole E. Drakos, Maximilien Franco, Ghassem Gozaliasl, Jeyhan Kartaltepe, Daizhong Liu, Henry Joy McCracken, Jason Rhodes, Brant Robertson, Sune Toft

“…Here, we use the high resolution and sensitivity of JWST to measure the host galaxy properties for 107 X-ray-selected type-I active galactic nuclei (AGNs) at 0.68 <  z  < 2.5 with rest-frame optical/near-infrared imaging from COSMOS-Web and PRIMER. …”
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A Novel Approach to Optimize Key Limitations of Azure Kinect DK for Efficient and Precise Leaf Area Measurement by Ziang Niu, Ting Huang, Chengjia Xu, Xinyue Sun, Mohamed Farag Taha, Yong He, Zhengjun Qiu

“…However, its further application in maize leaf area measurement is constrained by RGB–depth misalignment and limited sensitivity to detailed organ-level features. This study proposed a novel approach to address and optimize the limitations of the Azure Kinect DK through the multimodal coupling of RGB-D data for enhanced organ-level crop phenotyping. …”
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Barriers and facilitators of access to sexual and reproductive health services among migrant, internally displaced, asylum seeking and refugee women: A scoping review. by Pengdewendé Maurice Sawadogo, Drissa Sia, Yentéma Onadja, Idrissa Beogo, Gabriel Sangli, Nathalie Sawadogo, Assé Gnambani, Gaëtan Bassinga, Stephanie Robins, Eric Tchouaket Nguemeleu

“…Facilitators included mobile applications for translation and telehealth consultations, patients having a wide availability of information sources, the availability health promotion representatives, and healthcare providers being trained in cultural sensitivity, communication and person-centered care.…”
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Drp1–associated genes implicated in sepsis survival by Marissa D. Pokharel, Marissa D. Pokharel, Anlin Feng, Anlin Feng, Ying Liang, Ying Liang, Wenli Ma, Wenli Ma, Saurabh Aggarwal, Hoshang Unwalla, Stephen M. Black, Stephen M. Black, Stephen M. Black, Ting Wang, Ting Wang, Ting Wang

“…We confirmed that both GSs can successfully predict sepsis survival in both discovery and validation cohorts with high sensitivity and specificity, with the PPI-based GS showing enhanced prognostic performance. …”
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Genetic sources for barley (<i>Hordeum vulgare</i>) breeding in the Volga-Vyatka region by O. N. Shupletsova, I. N. Shchennikova

“…Of practical interest is application of cell-level breeding techniques to cultivars sensitive or moderately resistant to stressors. Accessions from VIR’s collection have been used to develop spring barley cultivars adapted to the cultivation conditions of the Volga-Vyatka region: more than 30 cultivars through hybridization and selection, and 6 cultivars with theuse of in vitro tissue culture.…”
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Differential expression of circulating microRNAs in lactating Holstein and Jersey cows exposed to heat stress by Jihwan Lee, Doosan Kim, Byeonghwi Lim, Gyeonglim Ryu, Hyeonguk Baek, Joohwan Kim, Seungmin Ha, Sangbum Kim, Seunghwan Lee, Taejeong Choi, Inchul Choi

“…Holstein cows, the primary dairy breed globally, are particularly sensitive to heat stress. In contrast, Jersey cows have shown greater heat tolerance, as demonstrated by phenotypic studies. …”
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Transition zone-based prostate-specific antigen density for differentiating clinically significant prostate cancer in PI-RADS score 3 lesions by Yongming Jin, Fei Chen, Gang Xu, Chaogang Wei, Congsong Dong

“…The diagnostic performances of prostate-specific antigen density (PSAD), TZ-adjusted PSAD (TZPSAD), and TZ-ratio (TZ volume/whole gland prostate volume) were analyzed. We calculated the sensitivity and specificity for each variable, the overall accuracy was evaluated with the area under the receiver operating characteristic curve (AUC). …”
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Complex high-risk indicated PCI (CHIP-PCI): is it safe to let fellows-in-training perform it as primary operators? by Tim Kinnaird, Zia Ul-Haq, Holly Morgan, Anirban Choudhury, Majd B Protty, Alexander Chase, David Hildick-Smith, Shantu Bundhoo, Saad Hasan, Diluka Premawardhana, Ahmed Hailan, Mohammed Shugaa Addin, Hussain Hussain

“…After adjusting for all variables, however, there was no difference in the primary outcome (OR 0.72, 95% 0.34 to 1.51) or any secondary outcomes. Sensitivity analyses restricted to patients with higher CHIP Scores (4+ and 5+) showed comparable IH-MACCE.Conclusions Training FIT as primary operators in CHIP-PCI appears to be feasible and safe and can be delivered within the standard training programme. …”
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