Comparative effectiveness of buprenorphine-naloxone versus methadone for treatment of opioid use disorder: a population-based observational study protocol in British Columbia, Cana... by Lawrence C McCandless, Malcolm Maclure, M Eugenia Socías, Evan Wood, Paul Gustafson, Robert W Platt, Bohdan Nosyk, Sander Greenland, Micah Piske, Trevor Thomson, Emanuel Krebs, Natt Hongdilokkul, Julie Bruneau, M Ehsan Karim, Judith I Tsui

“…We will determine the effectiveness of buprenorphine/naloxone vs methadone using intention-to-treat and per-protocol analyses—the former emulating flexible-dose trials and the latter focusing on the comparison of the two medication regimens offered at the optimal dose. Sensitivity analyses will be used to assess the robustness of results to heterogeneity in the patient population and threats to internal validity.Ethics and dissemination The protocol, cohort creation and analysis plan have been approved and classified as a quality improvement initiative exempt from ethical review (Providence Health Care Research Institute and the Simon Fraser University Office of Research Ethics). …”
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Effects of Ketamine 0.5 mg/kgBW administration as preemptive analgesia on analgesia duration and the need for Fentanyl following hysterectomy surgery: a randomized controlled trial by I. Fuadi, A. Zulfariansyah, Jacklin Edward Mokoginta

“…Preemptive analgesia prevents central sensitization before surgery, hampering postoperative hyperesthesia. …”
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Post-Implant Global Longitudinal Strain as a Predictor of Pacing-Induced Cardiomyopathy in Patients with Preserved Ejection Fraction Undergoing Pacemaker Placement by Sung Soo Kim, Hyung Wook Park, Hyung Ki Jeong

“…Receiver operating characteristic (ROC) analysis showed an area under curve (AUC) of 0.92 for GLS, with a GLS <–15.0 having 100% sensitivity and 80.9% specificity for predicting PICM. …”
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Savolitinib Induced Pathological Complete Response in Non-small Cell Lung Cancer with MET Amplification: A Case Report by Meng LU, Ran ZHANG, Baiwei LI, Haidi XU, Yongkuan GUO, Jian YOU, Bingsheng SUN

“…For advanced NSCLC with METex14m, Savolitinib has a high sensitivity as a member of tyrosine kinase inhibitors (TKIs). …”
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Frequency of Plasmid-Mediated Quinolone-Resistance (qnr) Genes in Pseudomonas aeruginosa Strains Isolated from Hospitalized Patients by Hamid Reza Goli, Sayede Fateme Moradi, Mohammad Reza Haghshenas, Ghazaleh Elahi, Mehrdad Gholami

“…The highest antibiotic sensitivity was observed for piperacillin/tazobactam, indicating it as the most effective treatment option. …”
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A novel cyber threat intelligence platform for evaluating the risk associated with smart agriculture by Navod Neranjan Thilakarathne, Muhammad Saifullah Abu Bakar, Pg Emeroylariffion Abas, Hayati Yassin

“…However, this proliferation has also given rise to significant security challenges, as cybercriminals increasingly target IoT devices to exploit vulnerabilities and gain access to sensitive data. This escalating threat landscape poses a severe issue across diverse domains where IoT is deployed, including agriculture, healthcare, and surveillance. …”
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A Retrospective Analysis of Thromboembolic Phenomena in Mechanically Ventilated Patients with COVID-19 by Fahad Faqihi, Abdulrahman Alharthy, Abdullah Balhamar, Nasir Nasim, Khaled Alanezi, Feisal Alaklobi, Ziad A. Memish, Mike Blaivas, Saleh A. Alqahtani, Dimitrios Karakitsos

“…Cardiac arrhythmias, lymphocytopenia, and increased D-dimers were more frequently observed in the TEP group compared to the non-TEP group of patients (all p<0.05). The sensitivity, specificity, and positive and negative predictive values of a cutoff D-dimer level of 3.0 μg/mL for predicting PE were 74.5%, 95.1%, 86.8%, and 91.9%, respectively. …”
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Spleen and Liver Stiffness Evaluation by ARFI Imaging: A Reliable Tool for a Short-Term Monitoring of Portal Hypertension? by Andreas Binzberger, Mark Hänle, Matthias Pfahler, Wolfgang Kratzer, Thomas Seufferlein, Eugen Zizer

“…To address the known large variability of values for spleen elastography, well-defined corresponding areas in the spleen were used for baseline and follow-up elastography. Sensitivity, specificity, and AUC-ROC values for both spleen and liver elastography monitoring of portal hypertension were calculated. …”
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Gender inequalities in prescribing and initiation patterns of guideline-recommended drugs after acute myocardial infarction by Irene López-Ferreruela, Sara Malo, Blanca Obón-Azuara, María José Rabanaque, Adriana Gamba, Sara Castel-Feced, Isabel Aguilar-Palacio

“…It is crucial to analyse them from an intersectional perspective, considering the influence of multiple axes of inequality on health, in order to develop gender-sensitive strategies with a multidisciplinary approach.…”
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A study on the global patterns in the design and development of ventricular assist devices: a visualization approach by Ajay K. Sood, A. K. Prasada Rao

“…The trend topics include miniaturization, machine learning, wireless, shear flow, and fiber-optic sensors.DiscussionThe latest technological advancements in VAD design are making them a more suitable choice for a large number of patients. …”
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Key CT markers for predicting haemorrhagic transformation after ischaemic stroke: a prospective cohort study in China by Ming Liu, Qian Wu, Yanan Wang, Junfeng Liu, Chenchen Wei

“…The early hypodensity &gt;1/3 of the middle cerebral artery (MCA) territory, Alberta Stroke Programme Early CT Score≤7, midline shift, hyperdense middle cerebral artery sign (HMCAS), poor collateral circulation, infarct core and penumbra was independently associated with the increased risk of HT (all p &lt; 0.05). The sensitivity of midline shift for predicting HT was only 3.5%, whereas its specificity was 99.8%. …”
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A novel method for detecting intracranial pressure changes by monitoring cerebral perfusion via electrical impedance tomography by Ming-xu Zhu, Jun-yao Li, Zhan-xiu Cai, Yu Wang, Wei-ce Wang, Yi-tong Guo, Guo-bin Gao, Qing-dong Guo, Xue-tao Shi, Wei-chen Li

“…Under both circumstances, ROC curve analysis showed that the comprehensive model of perfusion parameters based on the random forest algorithm had a sensitivity and specificity of more than 90% and an area under the curve (AUC) of more than 0.9 for detecting ICP increments of both 5 and 10 mmHg. …”
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A customized convolutional neural network-based approach for weeds identification in cotton crops by Hafiz Muhammad Faisal, Muhammad Aqib, Muhammad Aqib, Khalid Mahmood, Mejdl Safran, Sultan Alfarhood, Imran Ashraf

“…Weeds and pest infestation can be controlled through advanced digital gadgets like sensors and cameras which can provide a bulk of data to work with. …”
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Effect of m a tings among broiler breeder parent groups of different body weight on broiler performance :i. performance of broiler breeders by Süleyman Dere, M.Alı Tekeş

“…As the research material. 778 Avian female and 116 Peterson male broiler breeders were used Pareni male and female chickens were separately divided into three base body weight groups called light, middle and heavy al 22 weeks old age Separately three body weight subgroups which have almost similar variance and average values were obtained from base body weight groups by using sensitive sampling method Six male and 64 female broiler breeder parent chickens obtained from bodyweighl subgroups were housed in 9 pens during production period, Egg production percentage, egg weight, halchability, fertility, age at sexual maturity of broiler breeder chicken groups were determined. …”
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Prevalence of Subclinical Hypothyroidism in a Non-Diabetic Young Female Population and Its Impact on Diabetes and Cardiometabolic Risk by Nawoda Hewage, Udaya Wijesekara, Rasika Perera

“…Among obesity measures, visceral adiposity index (VAI) demonstrated the highest area under the curve and sensitivity for assessing SCH and cardiovascular disease (CVD) risk. …”
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Stress, anxiety, depression and sleep disturbance among healthcare professional during the COVID-19 pandemic: An umbrella review of 72 meta-analyses. by Mohammed Al Maqbali, Ahmad Alsayed, Ciara Hughes, Eileen Hacker, Geoffrey L Dickens

“…Subgroup analysis and sensitivity analyses were then conducted to explore the heterogeneity of the sample. …”
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Diagnostic accuracy of systemic immune-inflammation index for acute appendicitis in the geriatric population by Ömerul Faruk Aydın, Ali Cankut Tatlıparmak

“…A threshold of greater than 2289 yielded a sensitivity of 0.78 and specificity of 0.79. The positive predictive value was 0.90, while the negative predictive value was 0.60. …”
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Comparative Evaluation and Measure of Accuracy of ELISAs, CLIAs, and ECLIAs for the Detection of HIV Infection among Blood Donors in China by Le Chang, Junpeng Zhao, Fei Guo, Huimin Ji, Lu Zhang, Xinyi Jiang, Lunan Wang

“…CLIA and ECLIA assay had similar sensitivities with ELISAs but showed higher specificity (CLIA: 99.1%, 885/893; ECLIA: 99.0%, 884/893), concordance rate (CLIA: 99.2%, 1021/1029; ECLIA: 99.1%, 1020/1029), and positive predictive value (PPV) (CLIA: 94.4%, 136/144; ECLIA: 93.8%, 136/145) than most of ELISA kits (>5 ELISAs) (P<0.05). …”
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Intranasally Administered Extracellular Vesicles from Adipose Stem Cells Have Immunomodulatory Effects in a Mouse Model of Asthma by Sue Jean Mun, Shin Ae Kang, Hye-Kyung Park, Hak Sun Yu, Kyu-Sup Cho, Hwan-Jung Roh

“…Six-week-old female C57BL/6 mice were sensitized to ovalbumin (OVA) by intraperitoneal injection and challenged intranasally with OVA. …”
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Invited perspectives: Integrating hydrologic information into the next generation of landslide early warning systems by B. B. Mirus, B. B. Mirus, T. Bogaard, R. Greco, M. Stähli

“…More recently, broader access to commercial sensors and telemetry for real-time data transmission has invigorated new research into hydrometeorological thresholds for LEWSs. …”
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