Use of wearable technology in cardiac monitoring after cryptogenic stroke or embolic stroke of undetermined source: a systematic review by Jamie SY Ho, Elizabeth SY Ho, Leonard LL Yeo, William KF Kong, Tony YW Li, Benjamin YQ Tan, Mark Y Chan, Vijay K Sharma, Kian-Keong Poh, Ching-Hui Sia

“…Other devices investigated included patch sensors, handheld ECG recorders and PPG-based smartphone apps, which demonstrated feasibility in the post-cryptogenic stroke and post-ESUS setting. …”
Get full text

Opportunities and challenges for enhancing preconception health in primary care: qualitative study with women from ethnically diverse communities by Joe Kai, Nadeem Qureshi, Helena Tuomainen, Laura Cross-Bardell, Mandeep Bhoday

“…These included little prevailing culture of preparing for pregnancy and the realities of their pregnancies often being unplanned; and, for those planning pregnancy, sensitivity and maintaining secrecy when trying to conceive. …”
Get full text

Disentangling left-handed and right-handed neutrino effects in B c → τ ν ¯ τ $$ {B}_c\to \tau {\overline{\nu}}_{\tau } $$ decay by Quan-Yi Hu

“…Finally, in order to eliminate the uncertainties brought by the CKM matrix element V cb and the decay constant f B c $$ {f}_{B_c} $$ , we introduce the normalized distributions dΓ/(ΓdE a ) (a = π, ρ, μ, e), which are only sensitive to the right-handed neutrinos. We find that in each normalized distribution there exists a fixed point that is not related to any dimension-six effective operators considered in this work.…”
Get full text

When math legitimizes knowledge: a step by step approach to Bayes’ rule in diagnostic reasoning by Yung Bruno de Mello Gonzaga, André Demambre Bacchi, Vitor Borin Pardo de Souza

“…Through a clinical example involving the diagnosis of systemic lupus erythematosus, we use the Bayesian framework as a tool to help understand the difference between sensitivity/specificity (forward probability; deductive) and positive/negative predictive values (reverse probability: inductive). …”
Get full text

Association between cardiovascular health and metabolic dysfunction-associated steatotic liver disease: a nationwide cross-sectional study by Lian-Zhen Huang, Ze-Bin Ni, Wei-Feng Huang, Li-Ping Sheng, Yan-Qing Wang, Jin-Yan Zhang

“…Subgroup analysis showed a consistent negative correlation between LE8 score and MASLD, and sensitivity analysis validated the reliability of these findings. …”
Get full text

Revealing novel protein interaction partners of glyphosate in Escherichia coli by Alix Sarah Aldehoff, Dominique Türkowsky, Patrick Lohmann, Masun Nabhan Homsi, Ulrike Rolle–Kampczyk, Elke Ueberham, Jörg Lehmann, Martin von Bergen, Nico Jehmlich, Sven–Bastiaan Haange

“…Most microbes, including the gut bacterium Escherichia coli (E. coli), possess a glyphosate-sensitive class I EPSPS, making them vulnerable to glyphosate’s effects. …”
Get full text

Systemic doxycycline as an adjunct to nonsurgical periodontal therapy in diabetic patients with periodontitis: a systematic review and meta-analysis by Zheng Zhang, Zheng Zhang, Zhenyu Zhang, Guoquan Zhang

“…The robustness of the results was further confirmed by sensitivity analysis, despite the truth that significant heterogeneity was found among the included studies.ConclusionGingival inflammation in diabetic patients can be reduced more successfully by SRP combined with systemic doxycycline than by SRP alone, but this is insufficient in preventing periodontal tissue destruction.…”
Get full text

Transcriptome analysis reveals hypoxic response key genes and modules as well as adaptive mechanism of crucian carp (Carassius auratus) gill under hypoxic stress by Mengchao Xing, Mengchao Xing, Zhen Rong, Zhen Rong, Xin Zhao, Xin Zhao, Xiaowei Gao, Xiaowei Gao, Zhiguang Hou, Lihan Zhang, Lihan Zhang, Waiho Khor, Yihuan Xu, Yihuan Xu, Li Chen, Li Chen, Chengbin Wu, Chengbin Wu

“…Our findings provide valuable references for promoting the healthy aquaculture of hypoxic-sensitive fish and breeding hypoxia-tolerant fish varieties.…”
Get full text

Ecological and human health implications of mercury contamination in the coastal water by A. Mallongi, A.U. Rauf, R.D.P. Astuti, S. Palutturi, H. Ishak

“…The uncertainty and sensitivity tests for independent variables in human health risk were assessed by the Monte Carlo Simulation method. …”
Get full text

Optimizing Photovoltaic Panel Performance: A Comparative Study of Meta-Heuristic Algorithms by M. Sundar Rajan

“…However, these systems are highly sensitive to environmental factors such as temperature and global irradiance. …”
Get full text

What can qualitative research do for randomised controlled trials? A systematic mapping review by J Hewison, A O'Cathain, A Rudolph, K J THOMAS, S J Drabble

“…The potential value included optimising the intervention and trial conduct, facilitating interpretation of the trial findings, helping trialists to be sensitive to the human beings involved in trials, and saving money by steering researchers towards interventions more likely to be effective in future trials.Conclusions A large amount of qualitative research undertaken with specific trials has been published, addressing a wide range of aspects of trials, with the potential to improve the endeavour of generating evidence of effectiveness of health interventions. …”
Get full text

Options of dyslipidemia treatment at non-alcoholic fatty liver disease by M. V. Mayevskaya, M. A. Morozova

“…Results of several studies published at the moment demonstrate that at NAFLD lipid metabolism markers, and serum transaminase levels normalize, sensitivity to insulin increases, the liver histology pattern improves at phenofibrate treatment. …”
Get full text

Biomarkers of residual risk and all-cause mortality after acute coronary syndrome. by Anna Toso, Mario Leoncini, Mauro Maioli, Simona Villani, Francesco Bellandi

“…Methods: Levels of residual risk for the biomarkers were: low-density lipoprotein cholesterol (LDL-C) ≥ 70 mg/dl; high-sensitivity C reactive protein (hs-CRP) ≥ 2 mg/l; glycosylated hemoglobin (HbA1c) ≥ 7% in diabetic and ≥ 5.7% in non-diabetic patients; decrease in estimated glomerular filtration rate (eGFR) ≥ 25% compared to baseline. …”
Get full text

Exploring cognitive and neuroimaging profiles of dementia subtypes of individuals with dementia in the Democratic Republic of Congo by Jean Ikanga, Jean Ikanga, Saranya Sundaram Patel, Saranya Sundaram Patel, Megan Schwinne, Caterina Obenauf, Caterina Obenauf, Emmanuel Epenge, Guy Gikelekele, Nathan Tshengele, Immaculee Kavugho, Samuel Mampunza, Lelo Mananga, Charlotte E. Teunissen, Julio C. Rojas, Brandon Chan, Argentina Lario Lago, Joel H. Kramer, Adam L. Boxer, Andreas Jeromin, Emile Omba, Alvaro Alonso, Alden L. Gross

“…Biomarker cutoff scores were identified to optimize sensitivity and specificity. Individuals were stratified into one of four dementia subtypes—AD only, non-AD vascular, non-AD other, or mixed – based on combinations of abnormalities in these markers.ResultsAmong the 45 individuals with dementia, mixed dementia had the highest prevalence (42.4%), followed by AD-only (24.4%), non-AD other dementia (22.2%), and non-AD vascular dementia subtypes (11.1%). …”
Get full text

Barriers to orthodox medical care of prostate cancer in Ghana by Patrick Opoku Manu Maison, Prince Arkoh, Ahmed Sani, Emmanuel Ekow Mensah-Baidoo, Gifty Owusu, Esther Yeboah Danso, Nana Benyin Koufie, Susanna Andzie, Perez Gyamfi, Emmanuel Omane, Sylvester Antwi, Nallasivam Palanisamy, Clara Hwang, Eleanor Walker, Valerie Ofori Aboah, Evelyn Mawunyo Jiagge

“…There is a critical need for a culturally sensitive, multi-pronged strategy that enhances public education about the benefits of early diagnosis and fosters collaboration between traditional healers and orthodox healthcare providers to improve prostate cancer outcomes in Ghana.…”
Get full text

Research Progress on the Potential Pathogenesis of Persistent Postural–Perceptual Dizziness by Chen Qin, Ruyi Zhang, Zhihui Yan

“…Furthermore, PPPD patients are different from healthy individuals in spatial navigation ability, vestibular perception thresholds, central sensitization, and oxidative stress. These findings provide additional anatomical and behavioral insights into the pathogenesis of PPPD, suggesting that PPPD may arise from shifts in the interactions among emotional, visuo‐vestibular, and sensorimotor networks. …”
Get full text

Genome wide identification of Dof transcription factors in Carmine radish reveals RsDof33 role in cadmium stress and anthocyanin biosynthesis by Caiming Gou, Jia Li, Bo Chen, Guoting Cheng, Zhangfei Zheng, Hua Peng, Ahmed H. El-Sappah

“…The majority of RsDofs were tissue-specific and Cd-sensitive. The involvement of RsDof genes in Cd stress response and anthocyanin synthesis was verified using qRT-PCR. …”
Get full text

Association between Atopic Dermatitis and Dementia: Evidence from Systematic Review, Meta-analysis, and Mendelian Randomization by Yeon-Su Gwak, Seo-Yeon Kim, Chae-Eon Woo, Kihyuk Shin, Eunjeong Son, Jin-Woo Kim, Sung-Jin Kim, Tae-Jin Song, Hae Ryoun Park, Kihun Kim, Dai Sik Ko, Yun Hak Kim

“…Statistical analyses included the inverse-variance weighted (IVW) method, sensitivity tests, and MR-PRESSO for outliers. The adjustment accounted for various factors, including sex, age, smoking status, and other medical comorbidities, along with several additional variables. …”
Get full text

Spaciotemporal distribution characteristics of glacial lakes and the factors influencing the Southeast Tibetan Plateau from 1993 to 2023 by Yu Mingwei, Guo Yonggang, Zhang Jian, Li Feng, Su Libin, Qin Deshun

“…Abstract The southeastern region of Tibet, which serves as the primary concentration area for marine-type glaciers, has fostered a multitude of glacial lakes that are highly sensitive to global climate change. Glacial lakes play a crucial role in regulating the freshwater ecosystems of the region, but they also pose a significant threat to local infrastructure and populations due to flooding caused by glacial lake outbursts. …”
Get full text

Illuminating a biologics development challenge: systematic characterization of CHO cell-derived hydrolases identified in monoclonal antibody formulations by Melanie Maier, Linus Weiß, Nikolas Zeh, Valerie Schmieder-Todtenhaupt, Alireza Dehghani, Marius Nicolaus Felix, Daniel Heinzelmann, Benjamin Lindner, Moritz Schmidt, Joey Studts, Patrick Schulz, Bernd Reisinger, Kerstin Otte, Matthias Franzreb, Daniel Lakatos, Simon Fischer

“…By means of a highly sensitive liquid chromatography-tandem mass spectrometry method, we investigated seven different mAb products, resulting in the identification of 12 potentially PS-degrading hydrolases, including the strongly PS-degrading lipoprotein lipase (LPL). …”
Get full text