Decoding Vitellogenin Subtype Responses: A Molecular Approach to Biomarkers of Endocrine Disruption in <i>Scatophagus argus</i> by Meiqin Wu, Jun Zhang, Di Wu, Amina S. Moss, Weilong Wang

“…These findings confirm <i>vtgAb</i> as the most responsive subtype to oestrogen exposure in <i>S. argus</i> and highlight the species’ tolerance to EE2, as compared to more sensitive species like <i>Danio rerio</i>. This study shows the evolutionary conservation of <i>vtg</i> transcripts across teleost species and reinforces the importance of subtype-specific characterisation to advance their application as biomarkers for EEDCs, with significant implications for environmental monitoring and pollution regulation.…”
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Expanded non-invasive prenatal testing offers better detection of fetal copy number variations but not chromosomal aneuploidies. by Shaozhe Yang, Yuan Zhuang, Junfeng Li, Xiuhong Fu

“…The positive predictive value (PPV), sensitivity, specificity, and other indicators for different types of chromosomal abnormalities in NIPT/NIPT-plus screening were calculated. …”
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Lilla’s Heritage. Cultural Sketches of the Vay Branch in Hungary by Lili Veronika Békéssy

“…The lineage of this family, though only partially documented from a musicological point of view, unveils a significant impact on Dora’s abilities and sensitivities by diligently scrutinizing press and archival records from that era. …”
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Biotechnological bases of the development of cloned pig embryos by A. V. Lopukhov, G. N. Singina, N. A. Zinovieva

“…The method of manual cloning involves the removal of the oocyte nucleus with subsequent fusion with the donor cell without the use of micromanipulation techniques. The increased sensitivity of oocytes to the environmental conditions causes special requirements for the choice of the system for in vitro culture of cloned pig embryos. …”
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Aetiologies and Management of Retropharyngeal Abscess in Paediatric Age Group by Prem Kumar, Abhilasha Somashekhar

“…Initial antibiotics should be a broad spectrum until the pus culture sensitivity reports are available. There is a recent trend is Methicillin resistant staphylococcus aureus especially in younger children.  …”
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Long non-coding RNA MIR4435-2HG modulates pancreatic cancer stem cells and chemosensitivity to gemcitabine by targeting the miR-1252-5p/STAT1 by Baocheng Xie, Peishan Wu, Hongyu Liu, XiangDi Yang, Linxuan Huang

“…Moreover, depletion of MIR4435-2HG sensitized pancreatic cancer cells to gemcitabine-induced growth inhibition and ferroptosis. …”
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Identification of potential hydropower generation sites using geospatial techniques in the Megecha watershed of Ethiopia by Habtamu Wimego Anore, Tarun Kumar Lohani, Abebe Temesgen Ayalew

“…Curve number (CN2), saturated hydraulic conductivity (SOL_K), moist bulk density (SOL_BD), and available moisture in the soil layer (SOL_AWC) were among the most sensitive parameters assessed during the research. …”
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ADELLE: A global testing method for trans-eQTL mapping. by Takintayo Akinbiyi, Mary Sara McPeek, Mark Abney

“…Here, we propose ADELLE, a powerful statistical testing framework that requires only summary statistics and is designed to be most sensitive to SNPs that are associated with multiple gene expression levels, a characteristic of many trans-eQTLs. …”
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A Novel Network for Choroidal Segmentation Based on Enhanced Boundary Information by Wenbo Huang, Chaofan Qu, Yang Yan

“…Furthermore, the channel enhancement mechanism further refines the expression of salient channel futures, while the adaptive activation function improves the sensitivity of the network to boundary futures. A custom loss function, specifically designed to replace the conventional Mean Squared Error (MSE) loss, is utilized to optimize network parameters, leading to further improvements in segmentation performance. …”
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Prediction and Analysis of PDC Bit Wear in Conglomerate Layer with Machine Learning and Finite-Element Method by Li-qiang Wang, Ming-ji Shao, Wei Zhang, Zhi-peng Xiao, Shuo Yang, Ming-he Yang

“…The results of the sensitivity analysis method for the gray correlation degree show that the degree of influence of bit wear is in the order of temperature, back dip angle of the PDC cutter, linear speed, and bit pressure. …”
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Screening of serum biomarkers in patients with PCOS through lipid omics and ensemble machine learning. by Ji-Ying Chen, Wu-Jie Chen, Zhi-Ying Zhu, Shi Xu, Li-Lan Huang, Wen-Qing Tan, Yong-Gang Zhang, Yan-Li Zhao

“…When the AUC value of the test set of the constructed diagnostic panel model was 0.815, the model's accuracy in the test set was 0.74, specificity was 0.88, and sensitivity was 0.7. This study demonstrated the applicability and robustness of machine learning algorithms to analyze lipid metabolism data for efficient and reliable biomarker screening. …”
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Potential Use of C60/2-Hydroxypropyl-β-cyclodextrin Nanoparticles as a New Photosensitizer in the Treatment of Cancer by Abdulmalik Altaf, Hibah Aldawsari, Zainy M. Banjar, Daisuke Iohara, Makoto Anraku, Kaneto Uekama, Fumitoshi Hirayama

“…The resulting C60/HP-β-CyD nanoparticles were highly-sensitive to visible light and generated higher levels of 1O2 than protoporphyrin IX (PpIX). …”
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Droplets Cas13a‐RPA measurement delineates potential role for plasma circWDR37 in colorectal cancer by Jingsong Xu, Li Cao, Shuang Yang, Ying Jian, Yu Liu, Zhen Shen, Qian Liu, Xiang Chen, Min Li, Shun Li, Xiaolei Zuo, Min Li, Hua Wang

“…The 4% polyethylene glycol 8000 and 3% dextran‐10 significantly improved the response speed and sensitivity of one‐pot Cas13a‐RPA reaction. The detection limit of circWDR37 by µDCR was found to be 10 copies/mL, which is higher than that of qPCR. …”
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Genome sequence and evaluation of safety and probiotic potential of Lacticaseibacillus paracasei LC86 and Lacticaseibacillus casei LC89 by Ting Chen, Yunjiao Zhao, Yunjiao Zhao, Yixuan Fan, Yao Dong, Zhonghui Gai

“…They exhibited the capability to break down proteins and demonstrated sensitivity to a range of antibiotics. The oral LD50 for both LC86 and LC89 in mice was &gt;2 × 1010 CFU/kg.ConclusionThe experimental results above demonstrated the probiotic characteristics and safety of LC86 and LC89, indicating their potential as candidates for probiotics for human and animal applications.…”
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Oridonin: A natural terpenoid having the potential to modulate apoptosis and survival signaling in cancer by Abhishek Chauhan, Hemant Joshi, Divya Kandari, Diwakar Aggarwal, Ritu Chauhan, Hardeep Singh Tuli, Arpit Mehrotra, Abhilasha Sood, Ujjawal Sharma, Darin Mansor Mathkor, Shafiul Haque, Naveen Chandra Joshi, Laurent Dufossé

“…It demonstrates efficacy in inducing apoptosis, suppressing cancer cell proliferation, and sensitizing cells to conventional chemotherapeutics by modulating key signaling pathways like PI3K/AKT, MAPKs, and NF-κB. …”
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Diurnal changes of corneal epithelial and stromal thickness maps and visual quality in mild form of Fuchs’ endothelial corneal dystrophy by Iva Krolo, Aida Kasumović Bećirević, Ivana Radman, Armin Kasumović, Ines Matoc, Idoia Goñi Guarro, Ivan Sabol

“…Testing included measurement of uncorrected distance visual acuity (UDVA), best corrected twilight vision (TV), and contrast sensitivity function (CSF) testing (Vista Vision Far-Pola, DMD MedTech charts). …”
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Low-Grade Endometrial Stromal Sarcoma: A Case Report of a Rare Uterine Malignancy Mimicking Degenerative Uterine Leiomyoma in a Nulliparous Woman by Hyun Kyung Lee, Weon Jang, Kyoung Min Kim, Ji Soo Song

“…We suggest that susceptibility-weighted imaging could have aided in distinguishing between the two conditions due to its high sensitivity to blood products. Moreover, diffusion-weighted imaging revealed restriction along T2 low SI bands, with no restrictions within the bands themselves, potentially indicating a viable tumor along preserved myometrium. …”
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Deformation and Rupture of Thin Steel Plates due to Cumulative Loading from Underwater Shock and Bubble Collapse by Julian J. Lee, Malcolm J. Smith, James Huang, Geoffrey T. Paulgaard

“…The damage mechanisms and dynamic response of the plates were measured using dynamic displacement sensors, pressure gauges, and high-speed video. A fracture analysis was performed on the damaged plates to analyze the mechanisms of failure. …”
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Detection of bla NDM-1 Encoding Imepenemase among the Imipenem-Resistant Gram-Negative Bacilli Isolated from Various Clinical Samples at a Tertiary Care Hospital of Eastern Nepal:... by S. Gautam, N. R. Bhattarai, K. Rai, A. Poudyal, B. Khanal

“…Apart from performing only antimicrobial sensitivity test, phenotypic and molecular screening should be employed to find out the actual number of metallo-β-lactamase producers and the existence of the resistance gene.…”
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Effect of Molarity of Sodium Hydroxide on the Strength Behavior of Fiber-Reinforced Geopolymer Concrete Exposed to Elevated Temperature by Abbasali Saffar, Mohammad Ehsanifar, Seyed Mohammad Mirhoseini, Mohammad Javad Taheri Amiri

“…Based on the coefficient of determination obtained in the training and testing stages, ANN-WCA model had an acceptable performance in predicting the post-fire residual strength of FRGPC. Additionally, the sensitivity analysis manifested that the molarity of the FRGPC mixtures and the exposed temperature had the greatest effect and PP fibers had the least effect on post-fire residual strength of FRGPC.…”
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