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24901
Molecular profiling of bladder cancer xenografts defines relevant molecular subtypes and provides a resource for biomarker discovery.
Published 2025-02-01“…Bladder cancer (BLCA) genomic profiling has identified molecular subtypes with distinct clinical characteristics and variable sensitivities to frontline therapy. BLCAs can be categorized into luminal or basal subtypes based on their gene expression. …”
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24902
Enhanced detection of chronic wasting disease in muscle tissue harvested from infected white-tailed deer employing combined prion amplification assays.
Published 2024-01-01“…Conventional assays including immunohistochemistry (IHC) and enzyme-linked immunosorbent assay (ELISA) lack the sensitivity to detect low concentrations of prions presumed to be present outside neural or lymphatic tissues. …”
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24903
Could cough hypersensitivity symptom profile differentiate phenotypes of chronic cough?
Published 2024-11-01“…This study aimed to compare symptom features, such as cough triggers and associated throat sensations, of cough hypersensitivity in patients with asthmatic chronic cough and those with refractory chronic cough (RCC). …”
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24904
Classification of benign and malignant solid breast lesions on the ultrasound images based on the textural features: the importance of the perifocal lesion area
Published 2024-02-01“…The final model achieved a sensitivity of 98%, specificity of 96%, and accuracy of 97%. …”
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24905
Global surface eddy mixing ellipses: spatio-temporal variability and machine learning prediction
Published 2025-01-01“…Coarse-resolution climate models are sensitive to the specification of eddy diffusivity tensor. …”
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24906
Accelerating Multilingual Cryptocurrency Forensics: An NLP-Driven Approach for Efficient Mnemonic Identification
Published 2025-01-01“…Crucially, our TextCNN-driven approach processes data 40.47 times faster than the traditional method, significantly enhancing efficiency in time-sensitive forensic environments. This NLP-driven method not only maintains high accuracy while dramatically reducing processing time but also offers greater adaptability for diverse forensic needs compared to traditional techniques. …”
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24907
Gene Polymorphism of Antigen B Subunit 2 and Pathogenesis of Cystic Echinococcosis in Murine Model
Published 2025-02-01“…To upgrade the diagnostic sensitivity rates of the immunological techniques, a mixture of native hydatid antigens containing AgB is recommended to be used in the ser-diagnosis of this infection. …”
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24908
Validity of serum autotaxin and Doppler ultrasound as noninvasive markers of esophageal varices in patients with liver cirrhosis
Published 2025-01-01“…Child–Pugh classification, fibrosis-4 (FIB-4), age to platelet index (API), model for end-stage liver disease (MELD), platelet/splenic diameter, portal vein velocity, flow volume, and serum autotaxin were entered in stepwise logistic regression model for prediction of esophageal varices, and serum autotaxin, portal vein velocity, and flow volume were significant in multivariate regression analysis with sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of 96.25%, 75%, 93.9%, and 83.33%, respectively. …”
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24909
Dietary carotenoid intakes and biological aging among US adults, NHANES 1999–2018
Published 2025-01-01“…Subgroup analysis indicated that male, older individuals, smokers, alcohol drinkers, and less physically active individuals are particularly sensitive populations. Meanwhile, WQS regression and QG-comp analyses consistently indicated a negative association between mixed carotenoids exposure and four biological aging indices, highlighting that lutein/zeaxanthin and β-carotene were responsible for the outcomes. …”
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24910
Development and Evaluation of a Loop-Mediated Isothermal Amplification Assay for Diagnosis of Schistosoma mansoni Infection in Faecal Samples
Published 2018-01-01“…Current diagnostic tools are limited by suboptimal sensitivity, slow turn-around-time, affordability, and inability to distinguish current from past infections. …”
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24911
Quantitative 3-D investigation of faulting in deep mining using Mohr–Coulomb criterion and slip weakening law
Published 2025-01-01“…Our findings demonstrate that the k serves as a critical indicator of fault reactivity, with its sensitivity to φ and D m, significantly heightening the potential for seismic activities. …”
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24912
Clinical utility of hematological parameters in aplastic anemia
Published 2025-01-01“…Meanwhile, a combination of absolute neutrophil count, absolute reticulocyte count and mean sphered cell volume (AUC 0.893, 95% confidence interval 0.842–0.943, sensitivity 78.9%, specificity 85.7%) showed excellent precision for the differential diagnosis of severe aplastic anemia. …”
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24913
Investigating feature extraction by SIFT methods for prostate cancer early detection
Published 2025-03-01“…The adopted methodology was based on the comparative analysis and benchmarking of the performance of feature extraction based on SIFT against traditional image processing techniques with a generic representation on a number of metrics: sensitivity, specificity, and overall diagnostic accuracy. …”
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24914
Lactate/albumin ratio as a prognostic biomarker for in-hospital mortality in pediatric patients with necrotizing enterocolitis
Published 2025-02-01“…An L/A cutoff value of 0.56 demonstrated a sensitivity of 0.923 and specificity of 0.486, with an AUC of 0.725 from the ROC curve analysis. …”
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24915
ASTEC–MAAP Comparison of a 2 Inch Cold Leg LOCA until RPV Failure
Published 2018-01-01“…The choice of the accumulator gas expansion model, either isentropic or isothermal, affects the rate and total amount of coolant injected and thereby determines whether the core is quenched or overheated and attains a noncoolable geometry during reflooding. A sensitivity case was additionally simulated by each code to allow comparisons to be made with either accumulator gas expansion models. …”
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24916
Review of the Generation of Fractures and Change of Permeability due to Water-Shale Interaction in Shales
Published 2022-01-01“…However, if the generated fractures cannot serve as an effective flow channel, shale permeability will be impaired by clay swelling, water blocking, stress-sensitive, etc.…”
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24917
Comparison of Prevalence of blaNDM-1 Gene among Metallo-Beta Lactamase-Producing Multidrug-Resistant Fermenters and Nonfermenters in a Tertiary Care Hospital
Published 2024-01-01“…Materials and Methods: All clinical specimens received in the microbiology department for culture and sensitivity from indoor patients were included in study. …”
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24918
Serum Matrix Metalloproteinases and Risk of Urologic Cancers: A Bidirectional Mendelian Randomization Study
Published 2025-02-01“…We performed inverse variance-weighted MR as the primary method for calculating the overall effects of multiple instruments, while implementing additional MR methods and sensitivity analyses. Odds ratios (ORs) were employed to evaluate the causal relationship between serum MMPs and urologic cancers risk. …”
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24919
Diagnostic value of procalcitonin for differentiation between bacterial infection and noninfectious inflammation in febrile children with systemic autoimmune diseases
Published 2018-01-01“…PCT concentration cutoff value >1.2 ng/ml has the sensitivity of 83% (95% confidence interval [CI] 43.6–0.97) and specificity of 72% (95% CI 49.1–87.5), positive predictive value of 50% (95% CI 23.6–76.3) and negative predictive value 93% (95% CI 68.5–98.7). …”
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24920
Macroproperties vs. microstates in the classical simulation of critical phenomena in quench dynamics of 1D Ising models
Published 2025-01-01“…The long-time correlation length near the critical point is more sensitive to the full many-body state fidelity, and generally requires a large bond dimension MPS. …”
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