The Impact of a Submaximal Level of Exercise on Balance Performance in Older Persons by Hani Asilah Alias, Maria Justine

“…Thirteen community-dwelling older persons with intact foot sensation (age = 66.69 ± 8.17 years, BMI = 24.65 ± 4.08 kg/m2, female, n=6) volunteered to participate. …”
Get full text

Investigating Metabolic Phenotypes for Sarcoidosis Diagnosis and Exploring Immunometabolic Profiles to Unravel Disease Mechanisms by Mohammad Mehdi Banoei, Abdulrazagh Hashemi Shahraki, Kayo Santos, Gregory Holt, Mehdi Mirsaeidi

“…Metabolomics holds promise for identifying highly sensitive and specific biomarkers. This study aimed to leverage metabolomics for the early diagnosis of sarcoidosis and to identify metabolic phenotypes associated with disease progression. …”
Get full text

Genetic factors shaping the plasma lipidome and the relations to cardiometabolic risk in children and adolescentsResearch in context by Yun Huang, Sara Elizabeth Stinson, Malte Thodberg, Louise Aas Holm, Roman Thielemann, Karolina Sulek, Morten Asp Vonsild Lund, Cilius Esmann Fonvig, Min Kim, Kajetan Trost, Helene Bæk Juel, Trine Nielsen, Peter Rossing, Maja Thiele, Aleksander Krag, Cristina Legido-Quigley, Jens-Christian Holm, Torben Hansen

“…One-sample MR analysis identified positive causal associations between ceramides and liver enzymes, sphingomyelins and hemoglobin A1c (HbA1c), and phosphatidylethanolamines and high-sensitivity C-reactive protein in children and adolescents. …”
Get full text

D-dimer as a predictor of severity and outcome in acute pancreatitis by Joseph A, Harikrishnan CP, Oommen AN, Nair A

“…The study identified a D-dimer cutoff value of 1871 ng/L as an effective predictor of complications, with an area under the curve (AUC) of 0.870, yielding 87.5% sensitivity, 83.3% specificity, a positive predictive value of 77.78%, a negative predictive value of 90.90%, and 85% overall accuracy. …”
Get full text

Automated Estimation of Acute Infarct Volume from Noncontrast Head CT Using Image Intensity Inhomogeneity Correction by Keith A. Cauley, Gino J. Mongelluzzo, Samuel W. Fielden

“…We wished to test a hypothesis that image intensity inhomogeneity correction may provide a sensitive method for identifying the subtle regional hypodensity which is characteristic of early ischemic infarcts. …”
Get full text

Liquid chromatography-high resolution mass spectrometry based analysis of persistent mobile organic compounds in aqueous samples: Method development and optimization by Kyriaki Anagnostopoulou, Vasileios Alampanos, Eleni Evgenidou, Dimitra A. Lambropoulou

“…Validated under European directives (2002/657/EC and SANTE 11,813/2017), the study offers a sensitive, reliable, and regulatory-compliant framework for PMOC monitoring in water systems. …”
Get full text

Detectability of Self-lensing Flares of White Dwarfs with Compact Companions by Guy Nir, Joshua S. Bloom

“…We present a simulation tool that efficiently reproduces the main features of self-lensing flares and facilitates a detection sensitivity analysis for various sky surveys. We estimate the detection prospects for a handful of representative surveys when searching for systems of either two white dwarfs or a white dwarf with other compact objects, i.e., neutron stars and black holes. …”
Get full text

A Fosmid Cloning Strategy for Detecting the Widest Possible Spectrum of Microbes from the International Space Station Drinking Water System by Sangdun Choi, Mi Sook Chang, Tara Stuecker, Christine Chung, David A. Newcombe, Kasthuri Venkateswaran

“…The goals of this study were: to compare the sensitivity of the fosmid cloning strategy with that of traditional culture-based and 16S rRNA-based approaches and to detect the widest possible spectrum of microbial populations during the water purification process. …”
Get full text

Music Distraction among Young Drivers: Analysis by Gender and Experience by Carlos A. Catalina, Susana García-Herrero, Elvira Cabrerizo, Sixto Herrera, Santiago García-Pineda, Fatemeh Mohamadi, M. A. Mariscal

“…The study defined a conceptual model in which the data were analysed and evaluated mathematically through Bayesian networks. A sensitivity analysis was performed to evaluate the influence of music on driving speed. …”
Get full text

Integrated singlecell and bulk RNA-seq analysis identifies a prognostic signature related to inflammation in colorectal cancer by Wen Yin, Yanting Ao, Qian Jia, Chao Zhang, Liping Yuan, Sha Liu, Wanmeng Xiao, Gang Luo, Xiaomin Shi, Chen Xin, Maolin Chen, Muhan Lü, Zehui Yu

“…The risk score correlated strongly with the immune checkpoints PD1, PDL1, PDL2, and CTLA4, and it is possible that high-risk patients are more sensitive to treatment involving immune checkpoints. …”
Get full text

Development and Validation of New High Performance Liquid Chromatography Analytical Technique For Separation of Diclofenac Sodium and Lidocaine Hydrochloride From Ampoule Injection by Mohammed Ali Salih, Dlivan Fattah Aziz, Salar Ibrahim Ali

“…A performance and technical demonstration of the suggested Revers phase-HPLC method has been numerically challenged with support to process appropriateness, verticality, scales, simplicity, repeatability, sensitivity, stability, discovery and limits of quantification. …”
Get full text

Escherichia coli O157:H7 Bacteria Antibiotic Resistant Isolated from Flies at Food Courts in IPB Dramaga Campus by Muhammad Rizki Aminudin, Denny Widaya Lukman, Mirnawati Bachrum Sudarwanto, Herwin Pisestyani

“…E. coli O157:H7 isolates were tested for sensitivity to the antibiotic’s ciprofloxacin, ampicillin, tetracycline, trimethoprim-sulfamethoxazole, cefepime, chloramphenicol, ceftazidime, cefotaxime, and ceftriaxone using the Kirby Bauer disc diffusion method. …”
Get full text

Machine learning based identification of an amino acid metabolism related signature for predicting prognosis and immune microenvironment in pancreatic cancer by Xiaohong Liu, Xing Wang, Jie Ren, Yuan Fang, Minzhi Gu, Feihan Zhou, Ruiling Xiao, Xiyuan Luo, Jialu Bai, Decheng Jiang, Yuemeng Tang, Bo Ren, Lei You, Yupei Zhao

“…Subsequent GSEA was employed to unveil the enriched gene sets and signaling pathways within high- and low-risk subgroups. TMB and drug sensitivity analyses were carried out via Maftools and oncoPredict R packages. …”
Get full text

Logistic Regression Model Using Scheimpflug-Placido Cornea Topographer Parameters to Diagnose Keratoconus by Emre Altinkurt, Ozkan Avci, Orkun Muftuoglu, Adem Ugurlu, Zafer Cebeci, Kemal Turgay Ozbilen

“…The LRA model, which had the highest prediction ability, had 97.5% accuracy, 96.8% sensitivity, and 99.2% specificity. The most significant parameters were found to be BCVf (p=0.001), BCVb (Baiocchi Calossi Versaci back) (p=0.002), posterior rf (apical radius of the flattest meridian of the aspherotoric surface in 4.5 mm diameter of the cornea) (p=0.005), central corneal thickness (p=0.072), and minimum corneal thickness (p=0.494). …”
Get full text

Fault diagnosis of a CNC hobbing cutter through machine learning using three axis vibration data by Nagesh Tambake, Bhagyesh Deshmukh, Sujit Pardeshi, Sachin Salunkhe, Robert Cep, Emad Abouel Nasr

“…Real-world deployment challenges, including diverse operating conditions and generalizability across machines, were also discussed, with recommendations for incorporating multi-sensor data and transfer learning approaches in future research. …”
Get full text

Novel Study of Reaction Kinetics and Mass Transfer in Bioreactor Modelling: Prediction of Bioethanol Fermentation Performance by Saccharomyces cerevisiae on Continuous Fixed Bed Bi... by Christian Aslan, Hary Devianto, Vita Wonoputri, Ardiyan Harimawan

“…This modelling provides an overview of the influence of various independent variables, namely temperature, initial substrate concentration, cell concentration, superficial flow rate, reactor diameter, and solid particle diameter on various dependent variables, namely final product concentration, residence time, reactor length, reactor volume, product productivity, and pressure drop. The most sensitive parameters related to product productivity are temperature and cell concentration, so in its implementation, the temperature must be controlled at its optimum temperature, and the inoculum must be prepared with high cell concentration. …”
Get full text

Gene Therapy with HSV1-sr39TK/GCV Exhibits a Stronger Therapeutic Efficacy Than HSV1-TK/GCV in Rat C6 Glioma Cells by Lei-qing Li, Fang Shen, Xiao-yan Xu, Hong Zhang, Xiao-feng Yang, Wei-guo Liu

“…Accordingly, rat C6 glioma cells were first transfected with pCDNA-TK and pCDNA-sr39TK, respectively, and the gene transfection efficacy was verified by immunocytochemistry and western blot analysis. Then the in vivo sensitivity of these transfected C6-TK and C6-sr39TK cells to GCV was determined by 3-(4,5)-dimethylthiahiazo-(-z-y1)-3,5-di-phenytetrazoliumromide (MTT) colorimetric assay and Hoechst-propidium iodide (PI) staining. …”
Get full text

Azithromycin Inhibits Mucus Hypersecretion from Airway Epithelial Cells by Takeshi Shimizu, Shino Shimizu

“…To examine the in vivo effects of the 15-member macrolide, azithromycin (AZM), on mucus hypersecretion, we induced hypertrophic and metaplastic changes of goblet cells in rat nasal epithelium by intranasal instillation of ovalbumin (OVA) in OVA-sensitized rats, or by intranasal lipopolysaccharides (LPS) instillation. …”
Get full text

Identification of diabetic retinopathy lesions in fundus images by integrating CNN and vision mamba models. by Zenglei Liu, Ailian Gao, Hui Sheng, Xueling Wang

“…Furthermore, the vision mamba component incorporates the bidirectional state space method and positional embedding to enable the location sensitivity of visual data samples and meet the conditions for global relationship context. …”
Get full text

Working memory and the need for explainable AI – Scenarios from healthcare, social media and insurance by M. Liebherr, E. Gößwein, C. Kannen, A. Babiker, S. Al-Shakhsi, V. Staab, B.J. Li, R. Ali, C. Montag

“…XAI is particularly needed in AI systems that remain relatively closed, i.e. black box, on how to make decisions whether for complexity or commercial sensitivity. Still, many factors play an important role on whether people perceive a need for XAI. …”
Get full text