Role of denoisers in simulation-based inference from graph-structured data: a case study for position inference in an astroparticle detector by Venkat Roy, Aaron Higuera, Shixiao Liang, Christina Peters, Waheed U. Bajwa, Christopher D. Tunnell

“…The available simulated data in this case is the snapshots of the luminous responses of the photomultiplier tube sensors used within the dark matter detection experiment. …”
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Downregulation of PGC-1α Prevents the Beneficial Effect of EET-Heme Oxygenase-1 on Mitochondrial Integrity and Associated Metabolic Function in Obese Mice by Shailendra P. Singh, Lars Bellner, Luca Vanella, Jian Cao, John R. Falck, Attallah Kappas, Nader G. Abraham

“…EET is identified as an upstream positive regulator of PGC-1α that leads to increased HO-1, decreased BW and fasting blood glucose and increased insulin receptor phosphorylation, that is, increased insulin sensitivity and mitochondrial integrity, and possible use of EET-agonist for treatment of obesity and metabolic syndrome.…”
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O plano de carreira e a participação dos técnico-administrativos como indutores do desenvolvimento institucional: o caso de uma universidade federal do Brasil by Emerson Subtil Denicoli, Ana Lúcia Medeiros, Marli Terezinha Vieira

“…Os resultados apontam que o plano de carreira estimula o autodesenvolvimento e que os servidores se percebem como reflexivos, com bom nível de educação, aprendizagem e elevado grau de interesse em participar da gestão organizacional, porém, não se sentem sujeitos partícipes do processo de tomada de decisão que orienta o desenvolvimento institucional. …”
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Clinical utility of tumour mutational burden on efficacy of immune checkpoint inhibitors in malignant solid tumours: protocol for a systematic review and meta-analysis by Xiaoguang Yang, Yunming Li, Xuemei Xiang, Wang Guo, Pengfei Zhou

“…In addition, subgroup analysis, sensitivity analysis, heterogeneity analysis and publication bias will be conducted. …”
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The Heisenberg-RIXS instrument at the European XFEL by Justine Schlappa, Giacomo Ghiringhelli, Benjamin E. Van Kuiken, Martin Teichmann, Piter S. Miedema, Jan Torben Delitz, Natalia Gerasimova, Serguei Molodtsov, Luigi Adriano, Bernard Baranasic, Carsten Broers, Robert Carley, Patrick Gessler, Nahid Ghodrati, David Hickin, Le Phuong Hoang, Manuel Izquierdo, Laurent Mercadier, Giuseppe Mercurio, Sergii Parchenko, Marijan Stupar, Zhong Yin, Leonardo Martinelli, Giacomo Merzoni, Ying Ying Peng, Torben Reuss, Sreeju Sreekantan Nair Lalithambika, Simone Techert, Tim Laarmann, Simo Huotari, Christian Schroeter, Burkhard Langer, Tatjana Giessel, Jana Buchheim, Grzegorz Gwalt, Andrey Sokolov, Frank Siewert, Robby Buechner, Vinicius Vaz da Cruz, Sebastian Eckert, Chun-Yu Liu, Christian Sohrt, Christian Weniger, Annette Pietzsch, Stefan Neppl, Friedmar Senf, Andreas Scherz, Alexander Föhlisch

“…It is based on a spherical grating with variable line spacing and a position-sensitive 2D detector. Initially, two gratings were installed to adequately cover the whole photon energy range. …”
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An In Silico Study of the Interactions of Alkaloids from Cryptolepis sanguinolenta with Plasmodium falciparum Dihydrofolate Reductase and Dihydroorotate Dehydrogenase by Lois Kwane Kyei, Edward Ntim Gasu, Gilbert Boadu Ampomah, Jehoshaphat Oppong Mensah, Lawrence Sheringham Borquaye

“…We report herein that biscryptolepine and cryptomisrine (sb class), as well as cryptolepinone, cryptoheptine, cryptolepine, and neocryptolepine (pg class), are capable of inhibiting PfDHFR effectively in pyrimethamine sensitive and resistant cells. Also, our results show that alkaloids of the pg class can inhibit PfDHODH as FMN decoys, as well as direct enzyme inhibitors, thereby halting crucial protein function.…”
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Improving the Control Strategy of the DVR Compensator Based on an Adaptive Notch Filter with an Optimized PD Controller Using the IGWO Algorithm by Mohammed M. Alrashed, Aymen Flah, Masoud Dashtdar, Claude Ziad El-Bayeh, Mohamed F. Elnaggar

“…In order to improve the THD and voltage sag indicators of the sensitive load, the PD coefficients were adjusted using the IGWO algorithm. …”
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Characterization of Avocado (<i>Persea americana</i> Mill) Seed Extract from the Variety Semil 34 Cultivated in the Dominican Republic by Ramon Sanchez-Rosario, Luis Castillo, Alejandra Féliz-Jiménez, Sebastián Vargas, Ramón Pérez-Romero, Mónica Aquino, Maha T. Abutokaikah

“…However, the extract’s antioxidant capacity was found to be sensitive to pH changes, suggesting the need for stabilization when used in acidic or basic food matrices. …”
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A Prospective Cohort Study Evaluating the Ability of Anticipated Pain, Perceived Analgesic Needs, and Psychological Traits to Predict Pain and Analgesic Usage following Cesarean De... by Brendan Carvalho, Ming Zheng, Scott Harter, Pervez Sultan

“…Preoperative predictors included 4 validated psychological questionnaires (Anxiety Sensitivity Index (ASI), Fear of Pain (FPQ), Pain Catastrophizing Scale, and Eysenck Personality Questionnaire) and 3 simple ratings: expected postoperative pain (0–10), anticipated analgesic threshold (0–10), and perceived analgesic needs (0–10). …”
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A Study on the Role of LPA and ATX in Breast Cancer in Iraq by Anfal Akeel Taha, Hind Salman Jassim, Wafaa Fadhil Hamad

“…ROC analysis indicated that both LPA and ATX exhibited high diagnostic sensitivity (98%) and specificity (100%). In Iraqi women, elevated serum levels of LPA and ATX may serve as potential diagnostic biomarkers for breast cancer, highlighting their role in disease progression. …”
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Ten-year (2009–2019) epidemiological study of head and neck, salivary glands and upper aerodigestive tract cancers, and overall survival outcomes in the Northern Territory of Austr... by Hemi Patel, Nayellin Reyes-Chicuellar, Kate Thimbleby, Bhavya Balasubramanya, Suresh Mahendran

“…Targeted interventions are needed to improve service planning and delivery, considering identified risk factors and cultural sensitivities, and promoting Indigenous participation.…”
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Pan-Cancer Analysis of the Cuproptosis-Related Gene DLD by Jiahui Lin, Guowei Wang, Sha Cheng, Yanan Hu, Huan Li, Wanjiang Feng, Xiaoming Liu, Canxia Xu

“…The relationship of DLD with immune microenvironment immunomodulators, immune checkpoints, tumor mutational load (TMB), microsatellite instability (MSI), and oncology drug sensitivity was explored by correlation analysis. Results. …”
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Promoting ER stress in a plasmacytoid dendritic cell line drives fibroblast activation by Beatriz H. Ferreira, Inês S. Silva, Andreia Mendes, Fátima Leite-Pinheiro, Adrienne W. Paton, James C. Paton, Iola F. Duarte, Philippe Pierre, Catarina R. Almeida

“…This effect required expression of the ER stress signaling sensor protein kinase R-like ER kinase (PERK) in pDCs and was observed only upon direct contact between both cell types. …”
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Utility of anti-carbamylated protein antibodies in the diagnosis of early rheumatoid arthritis by Ashraf H Mohamed, Asmaa Enein, Noha Abdelsalam, Mona Balata, Sameh Abdellatif, Ehsan Rizk, Ahmed Fathy

“…Receiver-operating characteristic curve study for diagnostic efficacy of anti-CarP antibody in early RA diagnosis demonstrated a significant area under the curve, 0.950 (95% confidence interval, 0.912–0.987, P < 0.0001) and yielded a sensitivity of 85.4%, a specificity of 93.3%, a positive predictive value of 0.90, and a negative predictive value of 0.86. …”
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Constructing a machine learning model for systemic infection after kidney stone surgery based on CT values by Jiaxin Li, Yao Du, Gaoming Huang, Yawei Huang, Xiaoqing Xi, Zhenfeng Ye

“…The eXtreme Gradient Boosting (XGBoost) model was the best performer [AUC: 0.858; sensitivity: 0.877; specificity: 0.981; accuracy: 0.841; positive predictive value: 0.629; negative predictive value: 0.851]. …”
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Optimizing Rotary Cement Kiln modelling: A comparative analysis of metaheuristics in a real-world application by Miguel Ángel Castán-Lascorz, Antonio Alcaide-Moreno, Jorge Arroyo

“…A major challenge is the high proportion of invalid or infeasible solutions typical in industrial environments, compounded by the time-sensitive nature of real-world applications. Another notable difficulty lies in selecting among the plethora of metaheuristic methods, which may exhibit significant variations in search efficiency. …”
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Immunohistochemical Expression of HBME-1 in a Spectrum of Thyroid Neoplasms by Archi A. Chawla, Reeta Dhar, Shilpi Sahu

“…Conclusion: HBME-1, due to its high sensitivity, can be significantly used as a marker for identification and differentiation, particularly papillary thyroid carcinoma. …”
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Detecting the Black Hole Candidate Population in M51’s Young Massive Star Clusters: Constraints on Accreting Intermediate-mass Black Holes by Kristen C. Dage, Evangelia Tremou, Bolivia Cuevas Otahola, Eric W. Koch, Kwangmin Oh, Richard M. Plotkin, Vivian L. Tang, Muhammad Ridha Aldhalemi, Zainab Bustani, Mariam Ismail Fawaz, Hans J. Harff, Amna Khalyleh, Timothy McBride, Jesse Mason, Anthony Preston, Cortney Rinehart, Ethan Vinson, Gemma Anderson, Edward M. Cackett, Shih Ching Fu, Sebastian Kamann, Teresa Panurach, Renuka Pechetti, Payaswini Saikia, Susmita Sett, Ryan Urquhart, Christopher Usher

“…The lack of radio counterparts to X-ray sources we know to be associated with young massive star clusters in M51 suggests that we do not significantly detect hard-state intermediate-mass black holes (IMBHs)  ~10 ^4 M _⊙   or above. However, more sensitive radio facilities, like the Square Kilometre Array and next-generation Very Large Array, may be able to provide evidence for IMBHs with masses down to  ~10 ^3 M _⊙ .…”
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Smart Health Monitoring and Management System for Organizations Using Radio-Frequency Identification (RFID) Technology in Hospitals or Emergency Applications by Yaw-Wen Kuo, Yung-Chung Tsao, Web-Chang Chien, Yuh-Ming Huang, Lun-De Liao

“…One attractive feature of the system is its low cost due to the use of off-the-shelf devices and sensors that can be sourced and operated in our region. …”
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The Effectiveness of a Virtual Reality-Based Exergame Protocol in Improving Postural Balance in Older Adults During the COVID-19 Pandemic by Valeska Gatica-Rojas, María Isabel Camoglino-Escobar, Hernán Carrillo-Bestagno, Ricardo Cartes-Velásquez

“…The protocol incorporated 3D movement tracking using a sensor attached to the participants’ bodies to monitor postural sway in real time. …”
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