Efficient Anomaly Detection Algorithm for Heart Sound Signal by Zhihai Liu, Wen Liu, Zheng Gu, Feng Yang

“…The results demonstrated an Accuracy of 93.4%, a Specificity of 90.4% and a Sensitivity of 95.7%.…”
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Utility of Circadian Variability Patterns in Differentiating Origins of Premature Ventricular Complexes by Mu Chen, Qunshan Wang, Jian Sun, Peng-Pai Zhang, Wei Li, Rui Zhang, Bin-Feng Mo, Tai-Zhong Chen, Juyi Wan, Dong-Zhu Xu, Kazutaka Aonuma, Yi-Gang Li

“…Using a diurnal/nocturnal PVC burden ratio of 0.92 as the cutoff value to distinguish LVOT from ASV origin achieved 97% sensitivity and, as further verification, an accuracy of 89% (16/18) in a prospective cohort of patients with PVCs originating from either ASV or LVOT. …”
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Evaluation of undergraduate forensic medicine education in Nepal: a critical analysis using Schwab’s five commonplaces and Schubert’s curriculum images by Alok Atreya, Roshani Rajbanshi, Ritesh G. Menezes, Apurba Acharya

“…The current curriculum does not address cultural sensitivity, which should not be overlooked during medico-legal practices. …”
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The Clinical Significance of High Antimicrobial Resistance in Community-Acquired Urinary Tract Infections by Maria G. Zavala-Cerna, Midrori Segura-Cobos, Ricardo Gonzalez, Isidro G. Zavala-Trujillo, Silvia F. Navarro-Perez, Jose A. Rueda-Cruz, Fernando A. Satoscoy-Tovar

“…Higher frequencies of MDR bacteria were found among ESBL-E. coli, with resistance to ampicillin (100%), ceftriaxone (96%), gentamicin (57%), ciprofloxacin (89%), and TMP/SMX (53%). However, they were sensitive to fosfomycin (6.6%), nitrofurantoin (1.3%), and carbapenems (0%). …”
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How low-abundance amphibians shape functional diversity across tropical forest succession stages? by Fabio Zabala-Forero, Angela M. Cortés-Gómez, Nicolás Urbina-Cardona

“…Functional richness was sensitive to both vegetation types and species loss scenarios, while functional evenness and redundancy responded more specifically to the loss of low-abundance species. …”
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Illicium verum Extract and Trans-Anethole Attenuate Ovalbumin-Induced Airway Inflammation via Enhancement of Foxp3+ Regulatory T Cells and Inhibition of Th2 Cytokines in Mice by Yoon-Young Sung, Seung-Hyung Kim, Dong-Seon Kim, Ji-eun Lee, Ho Kyoung Kim

“…Asthma was induced in BALB/c mice by systemic sensitization to OVA, followed by intratracheal, intraperitoneal, and aerosol allergen challenges. …”
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Research on Wood Defects Feature Imbalance Optimization and Recognition by Xiao Wang

“…Results show that Modified Cross Entropy makes model more sensitive to hard samples regardless of the batchsize. …”
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Identification of fine antigenic epitopes of Tamdy virus glycoprotein Gn fragment and establishment of ELISA detection method by Yujiao Fu, Liping Liu, Beibei Zhang, Xiaoshan Chao, Junxia Jin, Ying Wang, Juntao Ding

“…Conclusions Eight precise epitopes were identified, and an indirect ELISA method based on fusion multiepitope peptide (r-Gn-MEPX2) was developed and implemented, featuring high sensitivity, accuracy, and specificity. Graphical Abstract…”
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Development of a nomogram for predicting malignancy in BI-RADS 4 breast lesions using contrast-enhanced ultrasound and shear wave elastography parameters by Tiantian Ren, Zhenzhen Gao, Lufeng Yang, Weibo Cheng, Xiao Luo

“…The nomogram based on these features demonstrated an AUC of 0.875 (95% CI 0.805–0.945), sensitivity of 88.6%, specificity of 68.4%, good calibration, and excellent clinical utility. …”
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Integrative analysis of immunogenic PANoptosis and experimental validation of cinobufagin-induced activation to enhance glioma immunotherapy by Yonghua Cai, Heng Xiao, Shuaishuai Xue, Peng Li, Zhengming Zhan, Jie Lin, Zibin Song, Jun Liu, Wei Xu, Qixiong Zhou, Songtao Qi, Xi’an Zhang, Ziyi Luo

“…Results Our findings indicate that high PANoScore gliomas showed increased immune cell infiltration, particularly effector T cells, and enhanced sensitivity to immunotherapies. Cinobufagin effectively induced PANoptosis, leading to increased immunogenic cell death, facilitated tumor-associated microglia/macrophages (TAMs) polarization towards an M1-like phenotype while augmenting CD4+/CD8 + T cell infiltration and activation. …”
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Altering the redox status of Chlamydia trachomatis directly impacts its developmental cycle progression by Vandana Singh, Scot P Ouellette

“…During ahpC knockdown, ROS levels were elevated, and the bacteria were sensitive to a broad set of peroxide stresses. Interestingly, we observed increased expression of EB-associated genes and concurrent higher production of EBs at an earlier time in the developmental cycle, indicating earlier secondary differentiation occurs under elevated oxidation conditions. …”
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High lipid diet can keep liver health but cause muscle oxidative stress of triploid rainbow trout treated with acute hypoxic challenge by Changye Li, Buying Han, Guoliang Sun, Haining Tian, Zezhong Wu, Changzhong Li, Yuqiong Meng, Rui Ma

“…Triploid rainbow trout (Oncorhynchus mykiss) is a hypoxia-sensitive and fatfish species that can efficiently utilize high-lipid diet (up to 30 %). …”
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Treatment of Miller I Mandibular Gingival Recessions Using PRF vs. Connective Graft by Hernan S. Garzon, Camilo Alfonso, Francisco J. Vega, Andrea García, Ana Muñoz, Gustavo Jaimes, Katherine Isaza, Katherine Rivera

“…Clinical variables, probing depth (PD), GR, keratinized tissue (KT), vestibular soft tissue thickness (VSTT), and teeth sensitivity (TS), were assessed at the baseline. GR, KT, VSTT, extraoral inflammation (EI), and patient discomfort (PaD) were assessed at 45 days. …”
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Assessment of <i>Alternaria</i> Toxins and Pesticides in Organic and Conventional Tomato Products: Insights into Contamination Patterns and Food Safety Implications by Tommaso Pacini, Teresa D’Amore, Stefano Sdogati, Emanuela Verdini, Rita Bibi, Angela Caporali, Elisa Cristofani, Carmen Maresca, Serenella Orsini, Alessandro Pelliccia, Eleonora Scoccia, Ivan Pecorelli

“…Some considerations about exposure assessment and risk characterization for ATs were also proposed in the overall population and in more sensitive and/or exposed subgroups, underlining the need for new focused toxicological and monitoring studies to establish reliable reference values. …”
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Unveiling cellular changes in leukaemia cell lines after cannabidiol treatment through lipidomics by David Chamoso-Sanchez, Martina Panini, Clarissa Caroli, Matilde Marani, Lorenzo Corsi, Francisco J Rupérez, Antonia Garcia, Federica Pellati

“…CBD treatment reduced cell viability and initiated apoptotic and necrotic processes in both cancer cell lines in a time and dose-dependent manner, showing acute myeloid leukaemia (HL-60) cells greater sensitivity than chronic myeloid leukaemia ones (K-562), without differences in the activation of caspases 3/7. …”
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A Comparative Study of Newly Developed HPLC-DAD and UHPLC-UV Assays for the Determination of Posaconazole in Bulk Powder and Suspension Dosage Form by Dalia A. Hamdy, Tarek S. Belal

“…Both assays were proven sensitive and selective according to ICH guidelines. …”
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Coupled Geomechanics and Flow Modeling of Fractured Reservoirs considering Matrix Permeability Anisotropy by Dawei Wu, Yuan Di, Yu-Shu Wu

“…The effect of geomechanics is crucial in the modeling of fractured reservoirs since fractures can be more stress-sensitive than the rock matrix. In fractured reservoirs, the microscale fractures are often homogenized into the matrix continuum leading to matrix permeability anisotropy. …”
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Parameters of labile organic carbon as the indicators of the stability of soil organic matter under different land use by Erika Balontayová, Juraj Hreško, Viera Petlušová, Peter Petluš, Bożena Dębska, Tomáš Lošák

“…The aim of this study was to determine the reliable and relatively simple indicators for detecting the chemical and physical stabilizations of OC, which would respond sensitively to land use. The study includes forest ecosystem (FE) and agroecosystem (AE) with different tillage intensities (reduced tillage, RT and conventional tillage, CT) on real farms. …”
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The Relationship of Hematologic Parameters and Lipid Profile with Acute Ischemic Stroke by Sibel Canbaz Kabay, Fatma Akkoyun Arıkan, Dursun Ceylan, Merve Yatmazoğlu Çetin, Niyazi Uysal, Muhammed Alperen Bardakçı, Gönül Akdağ, Mustafa Çetiner, Emine Saygın Uysal

“…As a result of ROC analysis, the area under the curve of hemoglobin, eosinophil, total-cholesterol, ldl-cholesterol, and triglyceride was significantly higher[(AUC: 0.710 95%CI: 0.60-0.81); Sensitivity=67.6%, Specificity=67.9%, p=0.001]. In the multivariable logistic regression model, only the NIHSS score (National Institutes Of Health Stroke Scale Scores) was independently associated with the degree of disability (p=0.001). …”
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Assessing Socket Fit Effects on Pressure and Shear at a Transtibial Residuum/Socket Interface by Kirstie M. Devin, Jinghua Tang, David Moser, Liudi Jiang

“…Interface pressure and shear sensors were placed at known prominent load-bearing sites of the transtibial residuum/socket interface, i.e., patellar tendon (PT), popliteal fossa (PF), and anterior–distal (AD) end, to measure real-time biomechanical interactions during standing and level walking. …”
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