Unidirectional MCM translocation away from ORC drives origin licensing by Agata Butryn, Julia F. Greiwe, Alessandro Costa

“…We observe that duplex DNA translocation by MCM involves a set of leading-strand contacts by the pre-sensor 1 ATPase hairpins and lagging-strand contacts by the helix-2-insert hairpins. …”
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Variation characteristics and influencing mechanisms of CO2 flux from grassland ecosystem in the Central Tianshan Mountains, China by Kun Zhang, Yu Wang, Ali Mamtimin, Yongqiang Liu

“…The intensification of carbon dioxide (CO2) fluxes in grassland ecosystems due to global climate change makes the achievement of carbon neutrality goals more challenging, particularly in arid regions with sensitive climates and fragile ecological environments. …”
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Optimal control strategies for toxoplasmosis disease transmission dynamics via harmonic mean-type incident rate by Usman Khan, Farhad Ali, Ohud A. Alqasem, Maysaa E. A. Elwahab, Ilyas Khan, Ariana Abdul Rahimzai

“…The stability of disease-free and endemic equilibrium are analyzed. Sensitivity analysis is also done for reproduction number. …”
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A multistage drug delivery approach for colorectal primary tumors and lymph node metastases by Yihang Yuan, Quanjun Lin, Hai-Yi Feng, Yunpeng Zhang, Xing Lai, Mao-Hua Zhu, Jue Wang, Jiangpei Shi, Yanhu Huang, Lele Zhang, Qin Lu, Zeli Yuan, Jonathan F. Lovell, Hong-Zhuan Chen, Peng Sun, Chao Fang

“…The liposomal membrane contains 1,2-dipalmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) (DPPG) and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), two phospholipids sensitive to secreted phospholipase A2 in human colorectal tumors. …”
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Bettered strength and fracture behavior of plain weave carbon fiber reinforced epoxy laminate with open hole under the influence of hole shape/size and strain rate by Rzgar Mhammed Abdalrahman, Sarkawt Rostam, Hameed Dwech Lafta

“…The literature has not adequately addressed the sensitivity of this composite to open holes. The novelty lies in defining the optimal effects that provide bettered Hole Tensile Strength (HTS) of this composite during applications. …”
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Calculation Method of Crowd Density in the Local Area of Subway Station Platform by GUO Longcan, AI Mingyu, PU Qi

“…［Result & Conclusion］ Compared with the traditional average density calculation method, the crowd density in the local area calculated by the proposed method is larger, and the change range is more obvious. It is more sensitive to the adjustment of train capacity and the change of passenger flow in and out of the platform, which better reflects the limit situation corresponding to the platform load extreme value and the duration of the high load state. …”
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Modulation of stress-related behaviour by preproglucagon neurons and hypothalamic projections to the nucleus of the solitary tract by Marie K. Holt, Natalia Valderrama, Maria J. Polanco, Imogen Hayter, Ellena G. Badenoch, Stefan Trapp, Linda Rinaman

“…Glucagon-like peptide-1 (GLP-1)-producing preproglucagon (PPG) neurons within the lower brainstem caudal nucleus of the solitary tract (cNTS) are particularly sensitive to stressful stimuli and are implicated in multiple physiological and behavioural responses to interoceptive and psychogenic threats. …”
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Predisposing Factors and Etiology of Deep Neck Space Infections – A Hospital-based Cross-sectional Study by Utkarsh Jain, Mahima Luthra, Sampan Singh Bist, Lovneesh Kumar, Vinish Kumar Agarwal

“…Streptococcus group of organisms were found in majority of the cases (19%) and cephalosporin was the most sensitive drug (100%). Dental infection was observed as the most common etiological cause (67.3%). …”
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Antibiotic Susceptibility of Bacteria Isolated from Open Fracture Grade III Presenting to Dr. Soetomo General Academic Hospital Surabaya by Raden Taufan Mulyo Wibisono, Dwikora Novembri Utomo, Agung Dwi Wahyu Widodo

“…The identification of the microbes was based on Gram-positive and Gram-negative categories, and the classification was based on susceptibility to antibiotics, whether sensitive, intermediate, and resistant. Results: The examination of the data from the microbiological culture results of patients with a diagnosis of open fracture grade III after debridement from October 2018 to September 2019 in Dr. …”
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Differential Cytotoxicity Responses by Dog and Rat Hepatocytes to Phospholipogenic Treatments by James K. Morelli, Paul J. Ciaccio

“…Dog and rat hepatocytes were treated with phospholipogenics to identify the more sensitive species and to determine whether lysosomal or mitochondrial changes were the primary cause of cytotoxicity. …”
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Characterizing Heterogeneity in Drivers’ Merging Maneuvers Using Two-Step Cluster Analysis by Gen Li, Lu Sun

“…Hypothesis test of accepted lead gaps and lag gaps indicate that merging drivers are more sensitive to the lag gaps under congestion. The proposed method can automatically identify the heterogeneity in merging drivers and the results obtained in this paper can be used to enhance the accuracy of the merge behavior models in microscopic simulation software.…”
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A rapid visual detection method for porcine teschovirus through reverse transcription recombinase-aided amplification coupled with lateral flow dipstick by Qiu-Yong Chen, Zhi-Hua Sun, Ru-Jing Chen, Xue-Min Wu, Yong-Liang Che, Ren-Jie Wu, Jing-Li Qiu, Bing He, Long-Bai Wang, Lun-Jiang Zhou

“…Conclusions The RT-RAA-LFD assay created in this research displayed quick response, specificity, and sensitivity, capable of successfully detecting PTV in less than 25 min, providing an easy-to-use diagnostic instrument for rapid and visual PTV detection, especially suitable for labs and low-resource environments.…”
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Scaphoid Fat Stripe Sign: Is It a Reliable Radiological Sign of Scaphoid Fracture in Children? by Pavle Manic, Stéphanie Schizas, Pierre-Yves Zambelli, Eleftheria Samara

“…Results: The results of the blind interpretation of the initial X-rays for the fat stripe sign showed 86% sensitivity and 58% specificity, with the negative predictive value reaching 92%. …”
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Evaluating YOLOv5s and YOLOv8s for Kitchen Fire Detection: A Comparative Analysis by Norisza Dalila Ismail, Rizauddin Ramli, Mohd Nizam Ab Rahman

“…Additionally, by offering the future work of integration of sensors with latest YOLO involvement can further optimize efficiency and fast detection rate. …”
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Comparative Evaluation of Effectiveness of IAVchip DNA Microarray in Influenza A Diagnosis by K. T. Sultankulova, O. V. Chervyakova, N. S. Kozhabergenov, K. A. Shorayeva, V. M. Strochkov, M. B. Orynbayev, N. T. Sandybayev, A. R. Sansyzbay, A. V. Vasin

“…IAVchip DNA microarray demonstrates higher diagnostic effectiveness (99.45%) in early influenza A diagnosis as compared to the real-time PCR (98.38%) and RT-PCR (96.22%), thus showing its clear superiority. Diagnostic sensitivity of IAVchip DNA microarray (100%) exceeds the same of RT-PCR (95.95%) and real-time RT-PCR (97.96%) in the range of estimated confidence intervals. …”
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Investigating the diagnostic accuracy of vertebral heart score, vertebral left atrium score and thoracic width measurement in cats with suspected cardiac problems by B. Ozdil, T. M. Parlak, M. Arican

“…This study aimed to evaluate vertebral heart score (VHS) in terms of sensitivity and accuracy of ra-diographic heart examination for early diagnosis of cardiac diseases in cats and to compare vertebral left atrium score (VLAS), N-terminal pro-B-type natriuretic peptide (Nt-proBNP) with thoracic width measurement (TWM). …”

Defend Against Property Inference Attack for Flight Operations Data Sharing in FedMeta Framework by Jin Lei, Weiyun Li, Meng Yue, Zhijun Wu

“…Motivated by the need for secure data sharing in aviation, as highlighted by the Federal Aviation Administration’s requirement for ADS-B Out equipment on aircraft to create a shared situational awareness environment, our method aims to prevent sensitive information leakage while maintaining model performance. …”
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Technology and practice of intelligent governance for financial data security by Peng HOU, Zhixin LI, Fei ZHANG, Xu SUN, Dan CHEN, Yihao CUI, Hanbing ZHANG, Yinan JIN, Hongfeng CHAI

“…In the “14th Five-Year Plan” era, the digitization of the financial industry has entered a phase of deepening and high-quality development.Strengthening Financial Data Security Governance (FDSG) and protecting financial data security have become an objective need and essential requirements for developing national economic security.FDSG utilizes data governance measures as a fundamental tool with a focus on sensitive data to ensure the comprehensive security of the entire lifecycle of financial data.It aims to promote data circulation among financial institutions, activate data value, and facilitate market-oriented allocation of financial data elements.FDSG is increasingly intertwined with big data, artificial intelligence, cloud computing, and blockchain technologies, transforming traditional data security governance into intelligent governance and accelerating the evolution of FDSG towards automation, intelligence, efficiency, and precision.FDSG’s essence, scope, and governance framework were introduced, and the core concepts and critical supporting technologies for the intellectual development of FDSG were elaborated, outlining the roadmap for intelligent governance.With consideration of FDSG’s demands and characteristics of intelligent technologies, vital directions for the practical application of intelligent technologies in FDSG were outlined, including data classification, data traceability, content control, privacy protection, and data twinning.Examples of current intelligent governance practices in banking, securities, and insurance industries were provided.Policy recommendations were proposed in the paper to promote the standardized and intelligent development of FDSG in China’s new era, aiming to foster the sustainable development of financial institutions and industries and ensure a healthy and secure environment for the future.…”
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Characteristics of Recycled Concrete Aggregate and its Implementation for Pavement Base Applications: A Review by Shravan Kumar Gangu, Shankar Sabavath

“…The findings from the literature indicated that RCA is source-dependent, moisture sensitive, and subjected to particle breakdown under wheel load that results in reduced shear strength. …”
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Long-Term Antithyroid Drug Therapy in Smoldering or Fluctuating-Type Graves’ Hyperthyroidism with Potassium Iodide by Ken Okamura

“…For initial and long-term ATD treatment, we must choose effective, safe, and economical drugs such as 100 mg potassium iodide (KI), although KI sensitivity varies in patients with GD. Thionamide, which has notorious side effects, is added only during the KI-resistant period.…”
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