Analysis of Dynamics Characteristic of Multi-span Cracked Rotor-rolling Bearing by Shen Qian, Xie Weisong, Liu Jiahang, He Zhenpeng

“…There is no essential effect on the periodic movement,the system response is sensitive to the change of the rolling bearing clearance. …”
Get full text

Methyl-Arginine Profile of Brain from Aged PINK1-KO+A53T-SNCA Mice Suggests Altered Mitochondrial Biogenesis by Georg Auburger, Suzana Gispert, Nadine Brehm

“…This pathway was further stressed by dysregulations of oxygen sensor EGLN3 and of nuclear TMPO. PSF and TMPO cooperate with dopaminergic differentiation factors LMX1B and NURR1. …”
Get full text

Update on Primary Biliary Cirrhosis by Jenny Heathcote

“…The antimitochondrial antibody remains the predominant hallmark, although not all patients test positive, even when the most sensitive techniques are used. The etiology of PBC remains elusive; studies suggest that the interlobular bile duct destruction is immune based, and associated autoimmune diseases are common. …”
Get full text

LEGO-Lipophosphonoxin membrane activity is enhanced by presence of phosphatidylethanolamine but hindered by outer membrane by Hana Brzobohatá, Milica Dugić, Viktor Mojr, Nitjawan Sahatsapan, Ivana Kóšiová, Tomáš Křížek, Tereza Dolejšová, Petra Lišková, Lukasz Cwiklik, Dominik Rejman, Radovan Fišer, Gabriela Mikušová

“…Gram-positive bacteria were more sensitive to LEGO-LPPO action compared to Gram-negatives, which was manifested as a delayed membrane permeabilization, higher minimal inhibitory concentration and lower amount of LEGO-LPPO bound to the cells. …”
Get full text

Beneficial Effects of Poplar Buds on Hyperglycemia, Dyslipidemia, Oxidative Stress, and Inflammation in Streptozotocin-Induced Type-2 Diabetes by Shiqin Peng, Ping Wei, Qun Lu, Rui Liu, Yue Ding, Jiuliang Zhang

“…The results showed that 50% fraction could increase insulin sensitivity and reduce insulin resistance, as well as decrease the levels of fasting blood glucose, glycated hemoglobin, and glycosylated serum proteins in diabetic mice. …”
Get full text

Simultaneous Quantification of Aspirin, Its Metabolite Salicylic Acid, and Salvianolic Acid B in Human Plasma Using UPLC-MS/MS by Weiyi Cao, Hezhi Yao, Zhenzhen Qian, Yi Wu, Shuge Wang, Rui Li, Rui Gao

“…To support clinical studies on drug-drug interactions (DDIs) between salvianolate injection and aspirin, a rapid and sensitive UPLC-MS/MS method for the simultaneous determination of aspirin (acetylsalicylic acid), its metabolite salicylic acid, and salvianolic acid B in human plasma was developed. …”
Get full text

Ferroptosis-Related Transcriptional Level Changes and the Role of CIRBP in Glioblastoma Cells Ferroptosis by Zijiang Yang, Ting Zhang, Xuanlin Zhu, Xiaobiao Zhang

“…We demonstrated that CIRBP modulates key aspects of cell death, thereby altering the sensitivity of glioblastoma cells to erastin-induced ferroptosis. …”
Get full text

Ultrasound Findings Suggestive of Malignancy in Thyroid Nodules Classified as Follicular Lesion of Undetermined Significance or Follicular Neoplasm based on the 2017 Bethesda Syste... by Heui Jin Jung, Na Lae Eun, Eun Ju Son, Jeong-Ah Kim, Ji Hyun Youk, Hye Sun Lee, Soyoung Jeon

“…Our criteria showed a highest area under the ROC curve (AUC) value of 0.771, sensitivity of 97.14%, accuracy of 77.14%, positive predictive value of 93.33%, negative predictive value of 95.24%, and specificity of 97.14%. …”
Get full text

Image Quality Assessment Based on Multi-Scale Representation and Shifting Transformer by Geng Fu, Ziyu Wang, Cuijuan Zhang, Zerong Qi, Mingzheng Hu, Shujun Fu, Yunfeng Zhang

“…In automatic control systems, sensors and cameras are often used to capture images of the environment or processes being monitored. …”
Get full text

circ_ZFR Is Linked to Paclitaxel Resistance in Cervical Cancer via miR-944 Sponging and IL-10 Upregulation by Xiaoqian Long, Meiyun Zheng, Youlin Yang, Yi Chen, Xiahui Zhang, Haiyan Zhang

“…In PTX-resistant CC cells, knocking down circ_ZFR expression decreased PTX resistance. circ_ZFR knockdown significantly reduced IL-10 expression via sponging miR-944, increasing PTX sensitivity in PTX-resistant CC cells. Conclusion. circ_ZFR knockdown has a considerable role in overwhelming CC-associated PTX resistance by modifying the axis of miR-944/IL-10 axis, suggesting that developing a circRNA target-based treatment could be considered prevent CC progression.…”
Get full text

Cardiometabolic Risk in Hyperlipidemic Men and Women by Michael Leutner, Christian Göbl, Alice Wielandner, Eleonora Howorka, Marlies Prünner, Latife Bozkurt, Jürgen Harreiter, Helmut Prosch, Oliver Schlager, Silvia Charwat-Resl, Alexandra Kautzky-Willer

“…HL-women were older and had overall more favourable concentrations of lipid parameters and liver enzymes but did not differ regarding vascular morphology and insulin sensitivity compared to HL-men of comparable body mass index (BMI).…”
Get full text

COMPARISON STUDY ON GREEN AND SUSTAINABLE BUILDING POLICIES IN DEVELOPED AND DEVELOPING COUNTRIES by I. J ONUOHA, S.A. OKEAHIALAM

“…That government intervention at the Federal level in Nigeria and South Africa is necessary to ensure sustainable green building policy formulation and implementation, and that efforts should be made by South Africa and Nigeria in particular to increase sensitization on the benefits of sustainable green building features among developers and investors and the public. …”
Get full text

A Novel Signal-Amplified Immunoassay for the Detection of C-Reactive Protein Using HRP-Doped Magnetic Nanoparticles as Labels with the Electrochemical Quartz Crystal Microbalance a... by Ning Gan, Ping Xiong, Ji Wang, Tianhua Li, Futao Hu, Yuting Cao, Lei Zheng

“…Compared with the enzyme-linked immunosorbent assay (ELISA), the immunoassay shows greatly improved sensitivity due to the significant amount of HRP labeled on signal tag. …”
Get full text

Clinical Significance of the Relationship between Progression-Free Survival or Postprogression Survival and Overall Survival in Patients with Extensive Disease-Small-Cell Lung Canc... by Hisao Imai, Keita Mori, Nodoka Watase, Sakae Fujimoto, Kyoichi Kaira, Masanobu Yamada, Koichi Minato

“…Type of relapse (refractory/sensitive) and the number of regimens administered after disease progression after the first-line chemotherapy were both significantly associated with PPS (p<0.05). …”
Get full text

Vibration Characteristics and Simulation Verification of the Dual-Rotor System for Aeroengines with Rub-Impact Coupling Faults by Pingping Ma, Mingxin Shan, Jingyu Zhai, Hao Zhang, Qingkai Han

“…The influence of the unbalanced position and the speed of high and low rotors on the vibration response of the dual rotor is obtained. The sensitivity of the vibration response of the dual rotor at different test points to rub-impact stiffness, clearance, and friction coefficient is compared. …”
Get full text

A dual-stream model based on PRNU and quaternion RGB for detecting fake faces. by Mohan Hua, Shuangliang Li, Jinwei Wang

“…The PRNU stream extracts the "camera fingerprint" feature by discerning the non-uniform response of the image sensor under varying lighting conditions, thereby encapsulating the overall distribution characteristics of globally manipulated faces. …”
Get full text

A Novel Hypothesis for Migraine Disease Mechanism: The Creation of a New Attractor Responsible for Migraine Disease Symptoms by Elham Baradari, Farnaz Garehdaghi, Yashar Sarbaz

“…The boundaries of the attractor are the sensitive brain areas in which any small trigger can start the ictal phase of the migraine. …”
Get full text

Evaluation of tensile properties of FRP composite laminates under varying strain rates and temperatures by Prahlad Srinivas Joshi, S.K. Panigrahi

“…Stress-strain relations reveal the strain rate and temperature sensitive behavior of composites. Glass, Glass-Carbon, Glass-metal epoxy composites showed higher peak tensile stress under room temperature with varying strain rates as compared to neat carbon epoxy composites. …”
Get full text

Pathophysiologic Mechanisms of Cardiovascular Disease in Obstructive Sleep Apnea Syndrome by Carlos Zamarrón, Luis Valdés Cuadrado, Rodolfo Álvarez-Sala

“…It has been found that CPAP therapy for OSAS provides an objective improvement in symptoms and cardiac function, decreases cardiovascular risk, improves insulin sensitivity, and normalises biomarkers. OSAS contributes to the pathogenesis of cardiovascular disease independently and by interaction with comorbidities. …”
Get full text

An effective vessel segmentation method using SLOA-HGC by Zerui Liu, Junliang Du, Weisi Dai, Wenke Zhu, Ziqing Ye, Lin Li, Zewei Liu, Linan Hu, Lin Chen, Lixiang Sun

“…Channel-aware self-attention (CAS) improves microfine vessel segmentation sensitivity. Heterogeneous adaptive pooling (HAP) facilitates accurate vessel edge segmentation through multi-scale feature extraction. …”
Get full text