The pro-inflammatory cytokine Tumor Necrosis Factor alpha (TNF-α) in Diabetic Nephropathy by Alia KH Mahmoud, Muhammed Ahmed Abd El Moety, Amal Khalifa Ahmed, Samer A. El-Sawy

“…They were compared to 25 people who appeared to be in good condition. TNF-α level in the serum was measured in 25 individuals with diabetes, 25 individuals with diabetic nephropathy, and 25 healthy controls by enzyme-linked immun-osorbent assay (ELISA). …”
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Sap-feeding insects do not respond uniformly to urbanization: The role of urban green spaces and species characteristics by Dávid Korányi, Ádám Kőrösi, András Orosz, Viktor Markó

“…Here, we studied how urbanization (defined as the proportion of impervious surfaces within a 200 and 500-m radius) affected canopy-dwelling phytophagous hemipterans (true bugs, true hoppers, and psyllids) on field maple (Acer campestre) trees. …”
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Preface by Nikoletta Hendrik

“…Secondly, we had a public reading of selected texts from Seneca and Epictetus, which happened under the title “the unconquerable power of the soul”. …”
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Whole transcriptome analysis of unmutated sporadic ALS patients' peripheral blood reveals phenotype-specific gene expression signature by Francesca Dragoni, Maria Garofalo, Rosalinda Di Gerlando, Bartolo Rizzo, Matteo Bordoni, Eveljn Scarian, Camilla Viola, Veronica Bettoni, Giuseppe Fiamingo, Danilo Tornabene, Lucia Scanu, Orietta Pansarasa, Luca Diamanti, Stella Gagliardi

“…According to clinical criteria, ALS patients can be classified into eight subgroups: classic, bulbar, pyramidal, pure lower motor neuron, flail arm, pure upper motor neuron, flail leg, and respiratory. There are no well-established molecular biomarkers for early diagnosis, prognosis, and progression monitoring of this fatal disease. …”
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Assessing the role of Chemokine (C–C motif) ligand 14 in AKI: a European consensus meeting by Jay L. Koyner, Christian Arndt, Jaume Baldira Martinez de Irujo, Sílvia Coelho, Manuel Garcia-Montesinos de la Peña, Luca di Girolamo, Michael Joannidis, Pablo Jorge-Monjas, Christian Koch, Steven Lobaz, Alain Meyer, Marlies Ostermann, Nicoletta Pertica, John R. Prowle, Jon Silversides, Alexander Zarbock, Jorge Echeverri, Kai Harenski, Lui G. Forni

“…The level of concern for discussion on RRT initiation between High and Low, and between Medium and Low CCL14 levels, showed significant differences.Conclusion Real world urinary CCL14 use appears to provide improved care options to patients at risk for persistent severe AKI. …”
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Is Rhodamine 123 an Appropriate Fluorescent Probe to Assess P-Glycoprotein Mediated Multidrug Resistance in Vinblastine-Resistant CHO Cells? by Jordi Pétriz, José Enrique O’Connor, Mercè Carmona, Joan García‐López

“…Our results suggest that the activity of P‐gp appears to be essential, but not sufficient to confer drug resistance, and that Rho123‐based functional assays of drug resistance should be evaluated for each cellular experimental model.…”
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Exploration of Digital Twin Design Mechanism of the Deep in Situ Rock Insulation Coring Device by Bo Yu, Heping Xie, Ling Chen, Wu Zhao, Zhiqiang He

“…It is significant to keep the original appearance of the core and obtain the in situ core for the analysis of deep geological fluid and the exploration of the law of geological disasters caused by large-scale geological exploitation. …”
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Assisted Parkinsonism Diagnosis Using Multimodal MRI—The Role of Clinical Insights by Tobias Meindl, Alexander Hapfelmeier, Tobias Mantel, Angela Jochim, Jonas Deppe, Silke Zwirner, Jan S. Kirschke, Yong Li, Bernhard Haslinger

“…Still, multinomial classification is hampered by imbalanced class frequencies. The most discriminatory variables were responsiveness to levodopa, vertical gaze palsy, and the volumes of subcortical structures, including the red nucleus. …”
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Study of height-spread sporadic-E layers observed in the South American Magnetic Anomaly by Juliano Moro, Juliano Moro, Jiyao Xu, José Valentin Bageston, Lígia Alves da Silva, Lígia Alves da Silva, Laysa Cristina Araújo Resende, Laysa Cristina Araújo Resende, Clezio Marcos De Nardin, Vânia Fátima Andrioli, Vânia Fátima Andrioli, Angela Machado Santos, Angela Machado Santos, Giorgio Arlan da Silva Picanço, Hui Li, Liu Zhengkuan, Chi Wang, Nelson Jorge Schuch

“…Among other findings, the statistical analysis reveals that the occurrence rate of HSEs layers is 9.8% during the analyzed period. The HSEs layers appeared predominantly at night and under geomagnetically quiet conditions. …”
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Polydatin-Induced Shift of Redox Balance and Its Anti-Cancer Impact on Human Osteosarcoma Cells by Alessio Cimmino, Magda Gioia, Maria Elisabetta Clementi, Isabella Faraoni, Stefano Marini, Chiara Ciaccio

“…Interestingly, PD’s ability to hinder cell adhesion and migration appears independent of its pro-oxidant effect. Analysis of the oxidative stress regulators SIRT1 and Nrf2 at the gene and protein levels using real-time PCR and Western blot indicates an early oxidative response to PD treatment. …”
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SIDOR de cuasi monopolio estatal venezolano a parte de una multinacional latina by RITA GIACALONE

“…Abstract Ten years after the privatization of the Siderurgica del Orinoco (Sidor) in Venezuela, this article analyzes what has happened since then in matters such as production, investments, exports, changes in property, and relationships with the Venezuelan socio-political environment. …”
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Exploring the general practitioners’ perception of the inter-professional care of rheumatoid arthritis patients (GEPRA—II): a qualitative interview study by Anne-Laure Yailian, Audrey Janoly-Dumenil, Emmanuelle Vignot, Aurélie Fontana, Charline Estublier, Cyrille Confavreux, Roland Chapurlat, Claude Dussart, Humbert de Freminville

“…Conclusions The implementation of a collaborative patient support programme in RA should be developed taking into account the barriers and facilitators identified by GPs who appeared to be aware of the causes of potential non-adherence, and were particularly interested in receiving more information about the therapeutic monitoring of patients by hospital professionals.…”
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Effect of Polymer Network Architecture on Adsorption Kinetics at Liquid–Liquid Interfaces: A Comparison Between Poly(NIPAM-co-AA) Copolymer Microgels and Interpenetrating Network M... by Galina A. Komarova, Elena Yu. Kozhunova, Rustam A. Gumerov, Igor I. Potemkin, Irina R. Nasimova

“…Additionally, hydrogen bonding between PNIPAM and PAA subchains appears to reduce the electrostatic energy barrier, enhancing the ability of IPN particles to successfully cover the liquid interface. …”
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TAS-102 Monotherapy and Combination Therapy with Bevacizumab for Metastatic Colorectal Cancer by Cheng-Jiang Liu, Ting Hu, Ping Shao, Wu-Yang Chu, Yu Cao, Feng Zhang

“…TAS-102 monotherapy and combination therapy with bevacizumab can significantly improve the survival of patients and prevent specific adverse events from happening.…”
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Tracing the Origin of Oxide Inclusions in Vacuum Arc Remelted Steel Ingots Using Trace Element Profiles and Strontium Isotope Ratios by Christoph Walkner, Gulnaz Mukhametzianova, Stefan Wagner, Jörg C. Korp, Andreas Graf, Johanna Irrgeher, Thomas C. Meisel, Thomas Prohaska

“…The inclusions were likely exogenous in origin and were primarily composed of calcium–aluminum oxides. They appeared to have undergone chemical modification during the casting and remelting process. …”
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Nonlocal Huygens’ meta-lens for high-quality-factor spin-multiplexing imaging by Jin Yao, Yubin Fan, Yunhui Gao, Rong Lin, Zhihui Wang, Mu Ku Chen, Shumin Xiao, Din Ping Tsai

“…However, current multiplexing meta-lenses lack spectral modulation, and crosstalk between different wavelengths hampers the imaging quality, especially for biological samples requiring precise wavelength specificity. …”
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Dimensional control of interface coupling-induced ferromagnetism in CaRuO3/SrCuO2 superlattices by Li Zhe, Shi Wenxiao, Zhang Jine, Zheng Jie, Wang Mengqin, Zhu ZhaoZhao, Han Furong, Zhang Hui, Xie Liming, Yunzhong Chen, Fengxia Hu, Baogen Shen, Yuansha Chen, Jirong Sun

“…The Hall and magnetoresistance measurements indicate the appearance of an interfacial FM state in the originally paramagnetic CaRuO3 layers when the CaRuO3 layer is in proximity to the chain-type SrCuO2 layers; this superlattice has the highest Curie temperature of ~75 K and perpendicular magnetic anisotropy. …”
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Pharmacological Effects of Antioxidant Mycosporine-Glycine in Alleviating Ultraviolet B-Induced Skin Photodamage: Insights from Metabolomic and Transcriptomic Analyses by Kai Wang, Ling Qin, Huan Lin, Mengke Yao, Junhan Cao, Qing Zhang, Changfeng Qu, Yingying He, Jinlai Miao, Ming Liu

“…M-Gly treatment improved skin appearance and reduced mast cell numbers, while also elevating antioxidant levels, including superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH). …”
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miR-34a Regulates Multidrug Resistance via Positively Modulating OAZ2 Signaling in Colon Cancer Cells by Yong Li, Ping Gong, Ji-xue Hou, Wei Huang, Xiao-ping Ma, Yu-li Wang, Jing Li, Xiao-bin Cui, Na Li

“…By using histoculture drug response assay, we further confirmed that clinical CCa samples with lower miR-34a expression appeared to be more resistant to chemotherapy. Functionally, ectopic expression of exogenous miR-34a resensitized multidrug-resistant HCT-8/OR cells to oxaliplatin treatment, whereas miR-34a inhibition augmented the oxaliplatin resistance in chemosensitive HCT-8 cells. …”
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Application of IgG-Derived Natural Treg Epitopes (IgG Tregitopes) to Antigen-Specific Tolerance Induction in a Murine Model of Type 1 Diabetes by Leslie P. Cousens, Yan Su, Elizabeth McClaine, Xin Li, Frances Terry, Robert Smith, Jinhee Lee, William Martin, David W. Scott, Anne S. De Groot

“…Suppression of immune responses to GAD65 epitopes ex vivo by Tregitope appeared to be more effective in assays using PBMC from a newly diagnosed diabetic subject than for other more established diabetic subjects, and correlation of the degree of suppression with predicted HLA restriction of the Tregitopes was confirmed. …”
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