The Empowerment of High-Impact Educational Practice Construct Based on Kelantan Rabbani Education Policy by Rahim Kamarul Zaman, Mujiburrahman Muhammad Saleh, Nur Shahidah Ab Hamid, Mazlan Ibrahim, Azizi Umar

“…However, the holistic element appears very subjective, making it difficult for Higher Education Providers (HEPs) to develop an integrated curriculum based on these aspirations. ‎…”
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A comparative study of the developability of full-length antibodies, fragments, and bispecific formats reveals higher stability risks for engineered constructs by Itzel Condado-Morales, Fabian Dingfelder, Isabel Waibel, Oliver M. Turnbull, Bhargav Patel, Zheng Cao, Jais Rose Bjelke, Susanne Nedergaard Grell, Anja Bennet, Alissa M. Hummer, Matthew I. J. Raybould, Charlotte M. Deane, Thomas Egebjerg, Nikolai Lorenzen, Paolo Arosio

“…However, the translation of these non-natural molecules into successful therapeutics can be hampered by developability challenges. Here, we systematically analyzed 64 different antibody constructs targeting Tumor Necrosis Factor (TNF) which cover 8 distinct molecular format families, encompassing full-length antibodies, various types of single chain variable fragments, and bispecifics. …”
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SOCIAL ECONOMIC CHANGE AS A PRECONDITION OF ETHNIC CONFLICTS: THE CASES OF OSH CONFLICTS IN 1990 AND 2010 by K. Hyunjung

“…Similarly, the Osh conflict in 2010 happened in the declining economy which was not only the result of the global economic crisis and difficulties in relations with Russia. …”
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Digital Diplomacy in the Discourse of Global Policy by I. V. Surma

“…In these circumstances, it is very important information without losing the initiative and applying new and modern means of communication with their particular style of communication, they can not fall the level of political culture, as happened with the diplomatic authorities of the USA and some other countries. …”
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Antenatal Steroid Therapy for Fetal Lung Maturation and the Subsequent Risk of Childhood Asthma: A Longitudinal Analysis by Jason D. Pole, Cameron A. Mustard, Teresa To, Joseph Beyene, Alexander C. Allen

“…Antenatal steroid therapy appears to be an independent risk factor for the development of asthma between 3 and 5 years of age.…”
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Silica-exposed patients with silicosis show shorter telomeres than do unexposed individuals: a pilot study in a population in southeastern Brazil by Marcos César Santos de Castro, Lucas de Carvalho Costa, Kaio Cezar Rodrigues Salum, Hermano Albuquerque de Castro, Patrícia Canto Ribeiro, Walter Costa, Angela Santos Ferreira Nani, Fabiana Barzotto Kohlrausch

“…Conclusions: Silica exposure appears to have an impact on TL, which was found to be shorter in patients with silicosis than in unexposed controls. …”
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In Patients With Hypertension, the Cortical Perfusion Index Measured by Contrast Enhanced Ultrasound Reveals a Sexual Dimorphism by Aikaterini Damianaki, Mariëlle Hendriks‐Balk, Wendy Brito, Erietta Polychronopoulou, Kenji Theiler, Menno Pruijm, Grégoire Wuerzner

“…Conclusions Women with arterial hypertension have a higher cortical microperfusion than men, while their microvascular reactivity to a CPT appears to be similar. This sexual dimorphism may have an impact on renal function decline, which needs further investigation.…”
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Angioblast Derived from ES Cells Construct Blood Vessels and Ameliorate Diabetic Polyneuropathy in Mice by Tatsuhito Himeno, Hideki Kamiya, Keiko Naruse, Zhao Cheng, Sachiko Ito, Taiga Shibata, Masaki Kondo, Jiro Kato, Tetsuji Okawa, Atsushi Fujiya, Hirohiko Suzuki, Tetsutaro Kito, Yoji Hamada, Yutaka Oiso, Kenichi Isobe, Jiro Nakamura

“…These results suggest that transplantation of angioblast like cells induced from embryonic stem cells appears to be a novel therapeutic strategy for diabetic polyneuropathy.…”
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Integrating lifestyle behaviors in school education: A proactive approach to preventive medicine by Mohamad Motevalli, Fatima Cody Stanford, Günther Apflauer, Katharina Christina Wirnitzer

“…Conclusions: Establishing school-based LE appears crucial for addressing the growing pandemic of chronic health conditions from their earliest origins.…”
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Health status and living conditions of families ascribed to the Family Health Units by Tatiana de Oliveira Sato, Patricia Driusso, Regina Helena Vitale Torkomian Joaquim, Thelma Simões Matsukura, Marcia Regina Cangiani Fabbro, Ana Cláudia Garcia de Oliveira Duarte, Ana Silvia Moccellin, Tania de Fátima Salvini, Silvia Helena Zem-Mascarenhas

“…In this context, the Primary Health Care appears as the gateway to the needs and health problems of the population, making it important to know the demographic and epidemiological profile for the development of their actions. …”
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Long-Term Effects of Activity Status in the Elderly on Cardiorespiratory Capacity, Blood Pressure, Blood Lipids, and Body Composition: A Five-Year Follow-Up Study by Eli Carmeli, Pini Orbach, David T. Lowenthal, Joav Merrick, Raymond Coleman

“…An active lifestyle was not sufficient to increase the physiological function of an individual.This study could not clearly demonstrate favorable differences for the physically active groups over the sedentary group with regard to several important physiological factors over the 5-year follow-up and it appears that the recommendation for, and the initiation of, adopting active lifestyles may not be sufficient on their own to significantly increase an individual's physiological functioning.…”
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A Novel Minimal Invasive Mouse Model of Extracorporeal Circulation by Shuhua Luo, Menglin Tang, Lei Du, Lina Gong, Jin Xu, Youwen Chen, Yabo Wang, Ke Lin, Qi An

“…Studies of ECC have been limited to large animals because of the complexity of the surgical procedures involved, which has hampered detailed understanding of ECC-induced injury. …”
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Innovations in Nipple-areolar Complex Reconstruction: Evaluation of a New Prosthesis by Michele Riccio, MD, Angelica Aquinati, MD, Mario Fordellone, PhD, Nicola Carboni, MD, Andrea Marchesini, MD, Francesco De Francesco, MD, PhD

“…Ninety percent of the participants expressed satisfaction or high satisfaction with the appearance and balance of the new NAC. The prosthetics enhanced the overall body self-image and self-regard of all the study participants. …”
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Hip Osteonecrosis Is Associated with Increased Plasma IL-33 Level by Jinhui Ma, Wanshou Guo, Zirong Li, Bailiang Wang, Shirui Li, Peng Wang

“…Our findings seem to indicate that IL-33 effects may be detrimental during ONFH, which appeared to be associated with the prognosis of ONFH. …”
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Therapeutic proteins immunogenicity: a peptide point of view by Feliciana Real-Fernandez, Fosca Errante, Andrea Di Santo, Anna Maria Papini, Paolo Rovero

“…Protein therapeutics are extensively used in the treatment of autoimmune diseases, but a subset of patients appears to be refractory to these treatments, mainly due to the development of an immune response to the drug. …”
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Risk Factors and Prevalence of Helicobacter pylori Infection in Persistent High Incidence Area of Gastric Carcinoma in Yangzhong City by Yangchun Zhu, Xiaoying Zhou, Junbei Wu, Jing Su, Guoxin Zhang

“…The prevalence of H. pylori infection was also associated with eating kipper food and fried food. No association between H. pylori prevalence and smoking or drinking was found. …”
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Mycobacteria Exploit Host GPR84 to Dampen Pro-Inflammatory Responses and Promote Infection in Macrophages by Reziya Wumaier, Ke Zhang, Jing Zhou, Zilu Wen, Zihan Chen, Geyang Luo, Hao Wang, Juliang Qin, Bing Du, Hua Ren, Yanzheng Song, Qian Gao, Bo Yan

“…Furthermore, from our studies in an in vitro macrophage <i>Mm</i> infection model, it appears that GPR84 inhibits pro-inflammatory cytokines expression and increases intracellular lipid droplet (LD) accumulation, thereby promoting intracellular bacterial survival. …”
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Classification of Melanoma and Nevus in Digital Images for Diagnosis of Skin Cancer by Muhammad Qasim Khan, Ayyaz Hussain, Saeed Ur Rehman, Umair Khan, Muazzam Maqsood, Kashif Mehmood, Muazzam A. Khan

“…However, it is sometimes hard to distinguish it from nevus due to their identical visual appearance and symptoms. The mortality rate because of this disease is higher than all other skin-related consolidated malignancies. …”
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The finding of black currants from sect. <i>Eucoreosma</i> (Grossulariaceae) in the central part of southern Primorsky Territory, Russia by L. A. Fedina, M. A. Polezhaeva, D. R. Iunusova, M. N. Koldaeva, A. Sh. Sabitov

“…Eucoreosma (Spach) Jancz. within a natural environment in the south of Primorsky Territory appears highly important. Previously, none of the black currant species was recorded as occurring in this area. …”
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Pharmacokinetics, biological effects, and distribution of (1→3)-β-D-glucan in blood and organs in rabbits by Minoru Yoshida, Robert I. Roth, Carl Grunfeld, Kenneth R. Feingold, Jack Levin

“…Over 97% of 125I-(1→3)-β-D-glucan was associated with cell-free plasma, and the majority in plasma appeared to be present in the unbound form (not associated with lipoproteins or plasma proteins). …”
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