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9641
Identification of p53 and Its Isoforms in Human Breast Carcinoma Cells
Published 2014-01-01“…One of the most intriguing findings is that mutant p53 appears as discrete dot-shaped regions within the nucleus of breast cancer cells. …”
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9642
Functions of BCL-XL at the Interface between Cell Death and Metabolism
Published 2013-01-01“…In addition, BCL-XL has been suggested to exert cytoprotective functions by sequestering a cytosolic pool of the pro-apoptotic transcription factor p53 and by binding to the voltage-dependent anion channel 1 (VDAC1), thereby inhibiting the so-called mitochondrial permeability transition (MPT). Thus, BCL-XL appears to play a prominent role in the regulation of multiple distinct types of cell death, including apoptosis and regulated necrosis. …”
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9643
Global research trends in necrotizing pancreatitis: a bibliometric analysis from 2013 to 2024
Published 2025-01-01“…The most frequent publications appeared in specialized journals such as “Pancreatology” and “Journal of Gastrointestinal Surgery.” …”
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9644
Pretreatment of Small-for-Size Grafts In Vivo by γ-Aminobutyric Acid Receptor Regulation against Oxidative Stress-Induced Injury in Rat Split Orthotopic Liver Transplantation
Published 2013-01-01“…Apoptotic induction and oxidative stress were observed after SOLT with an SFSG, and this damage was limited by GABAR regulation. GABAR regulation appeared to reduce DNA damage via the ATM/H2AX pathway and to promote cell survival via the PI3K/Akt pathway. …”
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9645
Acute Mesenteric Ischemia after Cardiac Surgery: An Analysis of 52 Patients
Published 2013-01-01“…Among intra- and postoperative parameters, CPB time (), dialysis (), inotropic support (), prolonged ventilator time (), and IABP support () appeared significantly higher in the AMI group than the control group. …”
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9646
Combined effects of Tai-Chi gait with mediolateral ground support perturbation on dynamic balance control
Published 2025-05-01“…Tai-Chi (TC) is a broadly used exercise that appeared to decrease the risk of falls. However, biomechanical mechanisms underlying the reduced fall risks following TC exercise remain unclear and hinder the ability to optimize TC intervention to target specific balance deficit disorders. …”
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9647
Forecasting Travel Speed in the Rainfall Days to Develop Suitable Variable Speed Limits Control Strategy for Less Driving Risk
Published 2021-01-01“…The experimental results show that a significant decrease happens in the travel speed in the rainfall day during peak hours. …”
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9648
Association of Adult Atopic Dermatitis with Impaired Oral Health and Oral Dysbiosis: A Case-Control Study
Published 2025-02-01“…Furthermore, AD patients had a significantly increased abundance of taxa correlated with oral diseases and a decreased abundance of bacteria associated with a healthy oral status. Conclusion: AD appears to be associated with poor oral health and oral dysbiosis. …”
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9649
A Case of Granulomatosis with Polyangiitis Causing Hydroureter and Hydronephrosis
Published 2014-01-01“…Granulomatosis with Polyangiitis (GPA, formerly known as Wegener) is a systemic vasculitis characterized by granulomatous involving upper and lower respiratory tract and can also cause necrotizing glomerulonephritis (Umemoto et al. 2012 and Takala et al. 2011). …”
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9650
Characterization of tumor evolution by functional clonality and phylogenetics in hepatocellular carcinoma
Published 2024-03-01“…However, ability to monitor tumor cell evolution is hampered by the presence of numerous passenger mutations that do not provide any biological consequences. …”
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9651
Comparing Host Plant Resistance, Engineered Resistance, and Insecticide Treatment for Control of Colorado Potato Beetle and Potato Leafhopper in Potatoes
Published 2011-01-01“…These data demonstrate that although each type of host plant resistance mechanism (Bt-cry3A or glandular trichomes) was as effective as the chemical control against one of the insects, neither provides adequate resistance to both Colorado potato beetle and potato leaf hopper.…”
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9652
Anti-TNF-Mediated Modulation of Prohepcidin Improves Iron Availability in Inflammatory Bowel Disease, in an IL-6-Mediated Fashion
Published 2017-01-01“…Anti-TNF therapy improves iron metabolism and, subsequently, anaemia in IBD. This effect appears to be related to the modulation of the cytokine network and specifically IL-6 leading to a relevant decrease of hepcidin, a master regulator of ACD.…”
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9653
Les géopolymères : matières premières et influence des paramètres de composition: a review
Published 2023-12-01“…Ces liants sont obtenus par activation alcaline de matériaux siliceux ou aluminosilicates. Ce papier résume les articles publiés récemment qui mettent en évidence les différents ingrédients entrant dans la composition des liants géopolymères : matières minérales servant de source alumino -silicates et activeurs chimiques utilisés pour la synthèse des géopolymères. …”
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9654
Comparative Analysis of the Full-Length Genome Sequence of a Clinical Isolate of Human Parainfluenza Virus 4B
Published 2012-01-01“…We are engaged in airborne transmission and epidemiology studies of respiratory pathogens, with particular interest in human parainfluenza virus type 4 (hPIV-4) and other lesser studied viruses. In this paper, hPIV-4 was detected in primary rhesus monkey kidney (PRMK) cells that had been inoculated with nasopharyngeal swab material obtained from a child with a mild upper respiratory tract illness. …”
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9655
Lung Matrix Metalloproteinase Activation following Partial Hepatic Ischemia/Reperfusion Injury in Rats
Published 2014-01-01“…Although the underlying mechanism needs further investigation, this is the first study in which the MMP activation in a distant organ is reported; this event is probably TNF-alpha-mediated and the lung appears as the first remote organ to be involved in hepatic I/R injury.…”
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9656
The Chromatin Pattern of Cell Nuclei Is of Prognostic Value for Renal Cell Carcinomas
Published 1998-01-01“…Using a series of 105 renal cell carcinomas (RCCs) we investigated whether features quantitatively describing the appearance of Feulgen‐stained nuclei and, more particularly, of their chromatin (on the basis of computer‐assisted microscopy) can contribute any significant prognostic information. …”
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9657
Follicular Thyroid Carcinoma Metastatic to the Kidney: Report of a Case with Cytohistologic Correlation
Published 2015-01-01“…The differential diagnoses of renal metastasis of FTC include the encapsulated follicular variant of papillary thyroid carcinoma (PTC), which possesses some of the nuclear features seen in conventional PTC but may occasionally be indistinguishable from FTC in cytologic preparations, and renal lesions such as benign thyroidization of the kidney and thyroid-like follicular carcinoma of the kidney, which mimic FTC in histologic appearance but do not stain with thyroid markers.…”
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9658
Differential Fasting Plasma Glucose and Ketone Body Levels in GHRKO versus 3xTg-AD Mice: A Potential Contributor to Aging-Related Cognitive Status?
Published 2017-01-01“…Cognitive function declines with age and appears to correlate with decreased cerebral metabolic rate (CMR). …”
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9659
Institutional Ethnography: An Approach to Explicate the Ruling Relations in Healthcare Institutions
Published 2024-06-01“…Achieving a proper understanding of how texts and individuals function together within an organization (what actually happens) enables the formulation and implementation of practical strategies for addressing issues in the field.…”
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9660
Levels of Physical Activity in Nursing Students
Published 2020-12-01“…<strong><br />Conclusions:</strong> an evaluation of the level of physical activity established by the international questionnaire was determined for the first time, these results being negative since the students lead a sedentary life which is detrimental to health and may affect the appearance of non-communicable diseases such as diabetes and arterial hypertension</p>…”
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