In Vitro Antibacterial and Antioxidant Activities, Pharmacokinetics, and In Silico Molecular Docking Study of Phytochemicals from the Roots of Ziziphus spina-christi by Hadush Gebrehiwot, Urgessa Ensermu, Aman Dekebo, Milkyas Endale, Tariku Nefo Duke

“…Conversely, the in silico molecular docking studies were attained via a Biovia Discovery Studio Visualizer 2021 in combination with the AutoDock Vina software. …”
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The Ubiquitin-Specific Protease 18 Promotes Hepatitis C Virus Production by Increasing Viral Infectivity by Yujia Li, Max Xuezhong Ma, Bo Qin, Liang-Tzung Lin, Christopher D. Richardson, Jordan Feld, Ian D. McGilvray, Limin Chen

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The steady-state level of plasma membrane ceramide is regulated by neutral sphingomyelinase 2 by Anne G. Ostermeyer-Fay, Abhay Kanodia, Ranjana Pathak, Maria Jose Hernandez-Corbacho, Aarnoud C. van der Spoel, Yusuf A. Hannun, Daniel Canals

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“But how true that is, I do not know”: the influence of written sources on the medicinal use of fungi across the western borderlands of the former Soviet Union by Julia Prakofjewa, Matteo Sartori, Raivo Kalle, Łukasz Łuczaj, Małgorzata Karbarz, Giulia Mattalia, Povilas Šarka, Baiba Prūse, Nataliya Stryamets, Martin Anegg, Natalia Kuznetsova, Valeria Kolosova, Olga Belichenko, Muhammad Abdul Aziz, Andrea Pieroni, Renata Sõukand

“…The highest numbers of medicinal uses were documented in Russia, Estonia and Ukraine. Studies published before the Soviet era listed 21 fungal taxa and one lichen species used in the study region. …”
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Metagenomic exploration and computational prediction of novel enzymes for polyethylene terephthalate degradation by Donya Afshar Jahanshahi, Mohammad Reza Rezaei Barzani, Mohammad Bahram, Shohreh Ariaeenejad, Kaveh Kavousi

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Obtaining strength-ductility combination in a laser additive manufactured (FeCoNi)86Al7Ti7 high-entropy alloy at cryogenic temperature by Kaiqiang Xie, Yacheng Fang, Pan Ma, Hong Yang, Shiguang Wan, Konda Gokuldoss Prashanth, Piter Gargarella, Yongkun Mu, Gang Wang, Yandong Jia

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The Chloroplastic Small Heat Shock Protein Gene KvHSP26 Is Induced by Various Abiotic Stresses in Kosteletzkya virginica by Xiaohua Liu, Lizi Zhao, Jianzhao Li, Lijun Duan, Kai Zhang, Xuqiang Qiao, Weihuan Li, Chengchao Zheng, Xiaoli Tang, Hongxia Zhang

“…Amino acid sequence alignment and phylogenetic analysis demonstrated that KvHSP26 shared 30%-77% homology with other sHSPs from Arabidopsis, cotton, durian, salvia, and soybean. Quantitative real-time PCR (qPCR) assays exhibited that KvHSP26 was constitutively expressed in different tissues such as leaves, stems, and roots, with a relatively higher expression in leaves. …”
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Unveiling the biological activities of Heliotropium indicum L. plant extracts: anti-inflammatory activities, GC–MS analysis, and in-silico molecular docking by Mst. Sadia Afroz Shoily, Md. Ekramul Islam, Nur Mohammad Rasel, Shahnaz Parvin, Jaytirmoy Barmon, Aqibul Hasan Aqib, Debendra Nath Roy, Mst. Shahnaj Parvin

“…Molecular docking was performed with PyRx and Biovia Discovery Studio, followed by drug-likeness analysis using Swiss ADME. …”
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Temperature-dependent luminescence of europium-doped Ga₂O₃ ceramics by Kuat K. Kumarbekov, Askhat B. Kakimov, Zhakyp T. Karipbayev, Murat T. Kassymzhanov, Mikhail G. Brik, Chong-geng Ma, Michał Piasecki, Yana Suchikova, Meldra Kemere, Marina Konuhova

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Nailfold Capillaroscopy in Early Stages of Mixed Connective Tissue Disease in a Sample of Egyptian Patients by Yasser A Elmotaleb Gazar, Hesham Salah Hamoud, Sherif Mohamed Ismail

“…Methodology: This cross-sectional study included forty patients diagnosed with MCTD according to Alarcón-Segovia and Villareal criteria and twenty patients with confirmed systemic sclerosis according to the American College of Rheumatology and the European League against Rheumatism classification criteria for Systemic Sclerosis. …”
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Varying circumstances surrounding opioid toxicity deaths across ethno-racial groups in Ontario, Canada: a population-based descriptive cross-sectional study by Tara Gomes, Mina Tadrous, Sophie A Kitchen, Frank Crichlow, Tonya J Campbell, Cynthia Damba, Colin H Johnson, Ashley Smoke

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Viability of pollen in sweet cherry (<i>Cerasus avium</i>) varieties of different ecogeographic origin in the Northwestern region of Russia by S. Yu. Orlova, A. V. Pavlov, V. G. Verzhuk

“…Twenty-four sweet cherry accessions belonging to five different groups were studied: I – Northwestern (bred at VIR); II – Central; III – Central Black Soil (all three are regions in Russia); IV – Belarus; and V – Estonia. Viability of pollen was assessed by germinating on an artificial medium with 10% sucrose and 0.6% agar. …”
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Operational research as a mechanism to improve treatment outcomes for drug-resistant TB in the WHO European Region by G.B. Migliori, O. Korotych, J. Achar, A. Ciobanu, G. Dravniece, M. Germanovych, E. Gurbanova, A. Hovhannesyan, N. Khachatryan, L. Kuksa, N. Lomtadze, M.L. Rich, A. Skrahina, A. Yedilbayev

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A retrospective cohort study: do patients with graves’ disease need to be euthyroid prior to surgery? by Abrar Al Jassim, Tim Wallace, Sarah Bouhabel, Agnieszka Majdan, Michael Hier, Veronique-Isabelle Forest, Richard Payne

“…Methods A retrospective cohort study was conducted at two Canadian centers, one in Montreal and the other in Nova Scotia. Sixty-seven patients undergoing thyroidectomy for Graves’ disease from January 2006 to December 2016 were evaluated. …”
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Comparative analysis of mesozooplankton size fraction structure in bivalve aquaculture embayments in Atlantic and Pacific Canadian coastal regions by Ruben D. Cordero, Anaïs Lacoursière-Roussel, Ramón Filgueira, Julie Arseneau, Jeffrey Barrell, Timothy J. Barrett, Christopher W. McKindsey, Daria Gallardi, Olivia Gibb, Terri Sutherland, Thomas Guyondet

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Deep learning in microbiome analysis: a comprehensive review of neural network models by Piotr Przymus, Krzysztof Rykaczewski, Adrián Martín-Segura, Jaak Truu, Enrique Carrillo De Santa Pau, Mikhail Kolev, Mikhail Kolev, Irina Naskinova, Aleksandra Gruca, Alexia Sampri, Alexia Sampri, Marcus Frohme, Alina Nechyporenko, Alina Nechyporenko

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Co-designing action-oriented mental health conversations between care providers and ageing Canadians in the community: a participatory mixed-methods study protocol by Carrie McAiney, Paul Holyoke, Heather McNeil, Justine L Giosa, Elizabeth Kalles, Nelly D Oelke, Katie Aubrecht, Olinda Habib Perez

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Preparation of pH-Responsive Tanshinone IIA-Loaded Calcium Alginate Nanoparticles and Their Anticancer Mechanisms by Tianying Ren, Jing Wang, Yingxin Ma, Yichen Huang, Somy Yoon, Lijun Mu, Ru Li, Xuekun Wang, Lina Zhang, Pan Li, Lusha Ji

“…<b>Background:</b> Tanshinone IIA (Tan IIA) is a lipophilic active constituent derived from the rhizomes and roots of <i>Salvia miltiorrhiza Bunge</i> (Danshen), a common Chinese medicinal herb. …”
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Medicinal plants with anti-SARS-CoV activity repurposing for treatment of COVID-19 infection: A systematic review and meta-analysis by EBENEZER OLUWAKEMI, BODEDE OLUSOLA, AWOLADE PAUL, JORDAAN MARYAM A., OGUNSAKIN ROPO E., SHAPI MICHAEL

“…More importantly, the literature analysis revealed that fruit extracts of Rheum palmatum L. and the compound cryptotanshinone isolated from the root of Salvia miltiorrhiza (IC50 = 0.8 ± 0.2 μmol L–1) were excellent candidates for anti--SARS-CoV targeting PLpro. …”
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Antipsychotic prescribing practices and patient, family member and healthcare professional perceptions of antipsychotic prescribing in acute care settings: a scoping review protoco... by Zahinoor Ismail, Daniel Niven, Kirsten Fiest, Lisa Burry, Karla D Krewulak, Natalia Jaworska, Stephana Julia Moss, Zara Stelfox

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