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  1. 21

    Effect of chitosan/inorganic nanomaterial scaffolds on bone regeneration and related influencing factors in animal models: A systematic review by Anjie Guo, Yi Zheng, Yu Zhong, Shuixue Mo, Shanbao Fang

    Published 2022-10-01
    “…None of these studies achieved high quality or had a low RoB. In the available studies, scaffolds reconstructed bone defects in radically different extensions. …”
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  3. 23

    The impact of weight loss interventions on disordered eating symptoms in people with overweight and obesity: a systematic review & meta-analysisResearch in context by Elena Tsompanaki, Dimitrios A. Koutoukidis, Gina Wren, Heather Tong, Annika Theodoulou, Danni Wang, Rebecca J. Park, Susan A. Jebb, Paul Aveyard

    Published 2025-02-01
    “…Sub-group analyses showed: (a) disordered eating scores improved more in people with an eating disorder at baseline compared with people without high scores, (b) no clear evidence that the association depended upon intervention type, and (c) disordered eating scores improved more in trials rated at low overall RoB. Interpretation: Despite heterogeneity in effect size, weight loss interventions consistently improved disordered eating scores. …”
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  4. 24

    Anterior Knee Pain and Knee Functional Scores Following Common Approaches to Tibial Shaft Fractures by Sarthak Parikh, DO, Laurel Marsh, BS, Mateao Anderson, BS, Jeremy Scott, DO, Amar Patel, DO, Christopher Hendrix, MD, Keivan Abtahi, DO

    Published 2025-03-01
    “…Comparative data for MPP and LPP remain limited. Overall RoB was low. Conclusion:. SP has better patient-reported outcomes and lower anterior knee pain than IP. …”
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  5. 25

    Efficacy and safety of transcutaneous electrical nerve stimulation (TENS) for acute and chronic pain in adults: a systematic review and meta-analysis of 381 studies (the meta-TENS... by Gareth Jones, Mark I. Johnson, Carole A. Paley, Matthew R. Mulvey, Priscilla G. Wittkopf

    Published 2022-02-01
    “…Pain intensity was lower during or immediately after TENS compared with placebo (91 RCTs, 92 samples, n=4841, SMD=−0·96 (95% CI −1·14 to –0·78), moderate-certainty evidence). Methodological (eg, RoB, sample size) and pain characteristics (eg, acute vs chronic, diagnosis) did not modify the effect. …”
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  6. 26

    Cannabis related side effects in otolaryngology: a scoping review by Jobanjit S. Phulka, Joel W. Howlett, Amanda Hu

    Published 2021-09-01
    “…Risk of bias assessment with RoB2 was low to high and ROBINS-1 was moderate to critical. …”
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  7. 27

    Lorentz violation alleviates gravitationally induced entanglement degradation by Wentao Liu, Cuihong Wen, Jieci Wang

    Published 2025-01-01
    “…At high mode frequencies, the effects of Lorentz violation are negligible, but they become significant at low frequencies. This suggests that investigating Lorentz violation at astrophysical scales requires low-frequency detectors, as the low energy of these fields enhances the significance of the Lorentz-violating field’s non-zero vacuum expectation value.…”
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  8. 28

    Home and outpatient electrostimulation in the treatment of urinary incontinence in women: a systematic review by Suele Moura Oliveira Coelho Caetano, Elma Gomes Pereira, Aline Moreira Ribeiro, Júlia Barros Brito, Clarcson Plácido Conceição dos Santos

    Published 2025-01-01
    “…There were no restrictions on date and language. The RoB2 and GRADE tools were used to assess methodological quality and evidence recommendation. …”
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  9. 29

    A comparison of the alterations of oral microbiome with fixed orthodontic therapy and clear aligners: a systematic review by Alessandra Lucchese, Marta Marcolina, Nicasio Mancini, Roberto Ferrarese, Serena Acconciaioco, Enrico Gherlone, Chiara Bonini, Maurizio Manuelli, Antonella Polimeni

    Published 2025-12-01
    “…Two scales were applied to assess the quality of scientific evidence: ROBINS-I and RoB 2.Results A total of 484 articles emerged of which 9 met our inclusion/exclusion criteria. …”
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  10. 30

    Ultrasound renal denervation in hypertensive patients: A systematic review and meta-analysis. by Roy Novri Ramadhan, Derren David Christian Homenta Rampengan, Felicia Angelica Gunawan, Nathania, Sebastian Emmanuel Willyanto, Hiroyuki Yamada, Mochammad Thaha, Satriyo Dwi Suryantoro, Maulana Antiyan Empitu

    Published 2025-01-01
    “…Quality appraisal used RoB 2.0, while meta-analysis used RevMan 5.4.<h4>Results</h4>Our analysis results indicated significant improvements in 24-hour, daytime, and home ambulatory blood pressure measurements, favoring the uRDN over control. …”
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  11. 31

    Acupoint stimulation for postpartum breastfeeding insufficiency: a systematic review and meta-analysis by Ya-Ching Chang, Yi-An Wang, Zi-Yu Chang, Jian-An Liao

    Published 2025-02-01
    “…The risks of bias were assessed using RoB 2.0. Results Twenty-four studies involving 3214 participants were included. …”
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  12. 32

    The effect of Shirodhara on essential hypertension: Systematic review and meta-analysis by Meenakshi Khapre, Dhanlika Dhanlika, Sriloy Mohanty, Amrita Mehndiratta

    Published 2025-01-01
    “…The Revised Cochrane Risk of Bias tool for randomized control trials (RoB-2) was used for the quality assessment of randomized control trials. …”
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  13. 33

    Efficacy and safety of antifibrotic drugs for interstitial lung diseases other than IPF: A systematic review, meta-analysis and trial sequential analysis. by Mei Yang, Yuying Tan, Ting Yang, Dan Xu, Mei Chen, Lei Chen

    Published 2025-01-01
    “…The risk of bias was rated with the RoB2 tool and certainty of evidence was assessed by the GRADE approach.…”
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  14. 34

    Cervical spine changes with functional appliance treatment: A systematic review and meta-analysis by Sandhya Murali, Annapurna Kannan, Vignesh Kailasam

    Published 2024-07-01
    “…Due to the heterogeneity and low quality of evidence, the results are to be considered critically.…”
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  15. 35

    Effect of exercise training on cardiac autonomic function in type 2 diabetes mellitus: a systematic review and meta-analysis by Sohini Raje, G Arun Maiya, Padmakumar R, Mukund A. Prabhu, Krishnananda Nayak, Shivashankara KN, BA Shastry, Megha Nataraj

    Published 2025-02-01
    “…The studies did not show any influence on the E:I and 30:15 ratio in the pooled analysis with a low risk of ineffectiveness for the exercise intervention. …”
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  16. 36

    Comparative efficacy of acupuncture therapies in premature ovarian failure: A systematic review and network meta-analysis by Yonghang Yi, Fengjun Ma, Yang Jiao, Rongqi Zhang, Yunhao Yi, Yuxia Ma

    Published 2025-05-01
    “…Confidence in evidence ranged from moderate to very low, with low overall confidence. Key methodologic weaknesses included insufficient allocation concealment, lack of blinding, and small sample sizes. …”
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  17. 37

    Evaluating agreement between individual nutrition randomised controlled trials and cohort studies - a meta-epidemiological study by Julia Stadelmaier, Gina Bantle, Lea Gorenflo, Eva Kiesswetter, Adriani Nikolakopoulou, Lukas Schwingshackl

    Published 2025-01-01
    “…Two reviewers independently extracted study characteristics and effect estimates and rated the risk of bias using RoB2 and ROBINS-E. Agreement of matched RCTs/cohort studies was analysed by pooling ratio of risk ratios (RRR) and difference of (standardised) mean differences (DSMD). …”
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  18. 38

    Pilates exercise in pregnancy: a systematic review and meta-analysis by Yuxuan Li, Heran Lu, Liuwei Zhang, Yijia Ren, Xiaotong Dai, Lin Lin

    Published 2025-02-01
    “…The quality of evidence was assessed using the Cochrane RoB Tool, and STATA 17.0 software was utilized to perform tests for heterogeneity, publication bias, and sensitivity analysis. …”
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  19. 39

    Is Dry Needling Effective When Combined with Other Therapies for Myofascial Trigger Points Associated with Neck Pain Symptoms? A Systematic Review and Meta-Analysis by César Fernández-De-Las-Peñas, Gustavo Plaza-Manzano, Jorge Sanchez-Infante, Guido F Gómez-Chiguano, Joshua A Cleland, José L. Arias-Buría, Ibai López-de-Uralde-Villanueva, Marcos J. Navarro-Santana

    Published 2021-01-01
    “…Outcomes included pain intensity, pain-related disability, pressure pain thresholds, and cervical range of motion. The risk of bias (RoB) was assessed using the Cochrane risk of bias tool, methodological quality was assessed with PEDro score, and the quality of evidence was assessed by using the GRADE approach. …”
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  20. 40

    The effects of active play interventions on children’s fundamental movement skills: a systematic review by Xinmiao Zhang, Changhao Tang, Miao Geng, Kai Li, Cong Liu, Yujun Cai

    Published 2025-01-01
    “…To assess the risk of bias in the literature, the RoB2.0 tool was used for RCTs, while the ROBINS-I 2.0 tool was applied to non-RCTs. …”
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