Pretreatment with Low-Dose Esketamine for Reduction of Propofol Injection Pain: A Randomized Controlled Trial by Danyun Fu, Dingding Wang, Wenxian Li, Yuan Han, Jie Jia

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Exoskeleton Training for Spinal Cord Injury Neuropathic Pain (ExSCIP): Protocol for a Phase 2 Feasibility Randomised Trial [version 1; peer review: 1 approved, 2 approved with rese... by Orlaith Doherty, Conor White, Nanna Brix Finnerup, Eimear Smith, Mark Pollock, Nathan Kirwan, Olive Lennon, Catherine Blake

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Evaluating a targeted selective speech, language, and communication intervention at scale – Protocol for the Happy Talk cluster randomised controlled trial. [version 3; peer review... by Pauline Frizelle, Darren Dahly, Aoife O'Shea, Aileen Murphy, Cristina McKean

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Evaluating a targeted selective speech, language, and communication intervention at scale – Protocol for the Happy Talk cluster randomised controlled trial. [version 2; peer review... by Pauline Frizelle, Darren Dahly, Aoife O'Shea, Aileen Murphy, Cristina McKean

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Association of Depression/Anxiety Symptoms with Neck Pain: A Systematic Review and Meta-Analysis of Literature in China by Fushui Liu, Ting Fang, Fanyuan Zhou, Meimei Zhao, Mei Chen, Jianyu You, Yuli Jin, Jinmei Xie, Zhongyong Liu

“…Controlled trials incorporating NP patients with anxiety/depression versus healthy people were contained. Two researchers screened each article and extracted data, respectively, and blinded to the findings of each other. …”
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At-Home Immersive Virtual Reality Exergames to Reduce Cardiometabolic Risk Among Office Workers: Protocol for a Randomized Controlled Trial by Jing Zhao, Akitomo Yasunaga, Andrew T Kaczynski, Hyuntae Park, Yufeng Luo, Jiuling Li, Ai Shibata, Kaori Ishii, Shohei Yano, Koichiro Oka, Mohammad Javad Koohsari

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The Nonmydriatic Fundus Camera in Diabetic Retinopathy Screening: A Cost-Effective Study with Evaluation for Future Large-Scale Application by Giuseppe Scarpa, Francesca Urban, Stela Vujosevic, Michele Tessarin, Giovanni Gallo, Annalisa Visentin, Emanuela Foglia, Lucrezia Ferrario, Edoardo Midena

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Impact of polygeNic risk score for glaucoma on psycHosocial ouTcomes (INSiGHT) study protocol. by Giorgina Maxwell, Robert Allen, Simone Kelley, Lucinda Hodge, Georgina L Hollitt, Mathias Seviiri, Daniel Thomson, Joshua Schmidt, Jamie E Craig, Sarah Cohen-Woods, Emmanuelle Souzeau

“…Potential clinical applications include identification of high-risk individuals, resulting in earlier diagnosis and treatment to prevent glaucoma blindness, and adjusted monitoring for low-risk individuals. …”
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Expression of MMP1, MMP3, and TIMP1 in intervertebral discs under simulated overload and microgravity conditions by Xuanyu Chen, Zhangfu Li, Chao Zheng, Ji Wu, Yong Hai

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Association of sildenafil use with age-related macular degeneration: a retrospective cohort study by Nicola Jaime Adderley, Krishnarajah Nirantharakumar, Anuradhaa Subramanian, Alastair K Denniston, Wen Hwa Lee, Ji Eun Diana Han, Jesse Coker

“…Objective Despite significant advances in clinical care and understanding of the underlying pathophysiology, age-related macular degeneration (AMD)—a major cause of global blindness—lacks effective treatment to prevent the irreversible degeneration of photoreceptors leading to central vision loss. …”
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Binaural auditory beats vs music of choice as audio distraction behaviour guidance technique among children: A randomized controlled trial by Bhuvanesh N. Bhusari, Shivayogi M. Hugar, Niraj Gokhale, Shweta Kajjari, Sanika Karmarkar, Varunika Sahai

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Mechanisms of Rhodopsin-Related Inherited Retinal Degeneration and Pharmacological Treatment Strategies by Maria Azam, Beata Jastrzebska

“…These mechanisms, however, often fail to prevent photoreceptor cell degradation and instead contribute to cell death under certain conditions. …”
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An Ensemble Based Machine Learning Classification for Automated Glaucoma Detection by Digvijay J. Pawar, Yuvraj K. Kanse, Suhas S. Patil

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Conservative treatment for cataract: state-of-the-art by S.Yu. Petrov, I.V. Kozlova, R.P. Poleva

“…&nbsp;Poleva</b><br> </p> <p> <b>Scientific Research Institute of Eye Diseases, Moscow, Russian Federation</b> </p> <p> <br> </p> <p> <i>Cataract is one of the leading causes of blindness worldwide and an important medical social issue in many countries. …”
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What Is New in Glaucoma: From Treatment to Biological Perspectives by Raffaele Nuzzi, Paola Marolo, Alessia Nuzzi

“…Glaucoma is a chronic silent disease and an irreversible cause of blindness worldwide. Research has made many efforts to improve disease control and especially to anticipate both early diagnosis and treatment of advanced stages of glaucoma. …”
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Role of ARMS2/HTRA1 risk alleles in the pathogenesis of neovascular age-related macular degeneration by Yang Pan, Takeshi Iwata

“…In this comprehensive review, we provide an overview of the role played by ARMS2/HTRA1 risk alleles in neovascular AMD pathogenesis, covering GWAS, in vitro studies, and animal models, shedding light on their underlying molecular genetic mechanisms. Further extensive research is also imperative, including confirmation of these findings, identifying novel treatment targets, and advancing primary and secondary prevention strategies for AMD.…”
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The fundus changes in pathological myopia by Markosyan G.A., Tarutta E.P, Tarasova N.A., Maksimova M.V.

“…Maksimova — Researcher of the Department of Refractive Pathology, ORCID iD 0000-0002-3749-3668.…”
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Pharmacotherapy for AMD: state-of-the-art by I.A. Koroleva, A.A. Gvetadze, T.B. Romanova

“…Agents which prevent neovascularization by inhibiting vascular endothelial growth factor (VEGF) are currently used to manage this rapidly progressing type of AMD. …”
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Improving Clinical Management of Diabetic Macular Edema: Insights from a Global Survey of Patients, Healthcare Providers, and Clinic Staff by Focke Ziemssen, Michelle Sylvanowicz, Winfried M. Amoaku, Tariq Aslam, Bora Eldem, Robert P. Finger, Richard P. Gale, Laurent Kodjikian, Jean-François Korobelnik, Xiaofeng Lin, Anat Loewenstein, Paul Mitchell, Moira Murphy, David R. Owens, Nick Parker, Ian Pearce, Francisco J. Rodríguez, Jude Stern, S. James Talks, David T. Wong, Tien Yin Wong, Jane Barratt

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Early diagnosis and the effect of treatment compliance on the prognosis and progression of glaucomatous optic neuropathy by S.V. Diordiychuk, A.V. Kuroyedov, N.E. Fomin, O.V. Gapon’ko, V.V. Gorodnichiy, I.V. Kondrakova, N.M. Sol’nov

“…The described disease course has demonstrated that several factors affect the prognosis and development of a chronic progressive neurodegenerative disorder, which results in irreversible blindness. These factors include early diagnosis, accessible and effective screening system, rational management strategy that implies the drug change to prevent the reduction in therapeutic effect, and patient adherence to treatment that involves explaining the causes and characteristics of disease cours e, potential complications with recommendation noncompliance, and a professional work a doctor with a patient.…”
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