Exploring the NANOG-TET2 interaction interface. Effects of a selected mutation and hypothesis on the clinical correlation with anemias by Claudia Testi, Roberta Piacentini, Roberta Piacentini, Alessandro Perrone, Chiara Bartoli, Daniele Leso, Domitilla Pavia, Elisa Pistolesi, Flavio Scipione, Irene Cotronea, Marco Adinolfi Falcone, Marco Ierani, Alberto Boffi, Lorenzo Di Rienzo

“…Our findings indicate that the single-point mutation might effectively reduce the TET2-NANOG interaction, which would consequently impair cells differentiation and hematopoiesis process, consistent with the clinical presentation of pure red cell aplastic anemia. These results, along with the proposed computational method, provide insights for establishing clinical correlations between variants of uncertain significance and anemias in general, comprising common hematological problems widespread in the world population and for which dedicated NGS panels are still not available.…”
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AnaDetect: An extensive dataset for advancing anemia detection, diagnostic methods, and predictive analytics in healthcareMendeley Data by Mayen Uddin Mojumdar, Dhiman Sarker, Md Assaduzzaman, Md. Anisul Haque Sajeeb, Md. Mohaimenur Rahman, Md Shadikul Bari, Shah Md Tanvir Siddiquee, Narayan Ranjan Chakraborty

“…Anemia is a critical medical condition in public health concern in tropical and subtropical areas, and understanding its hematological changes is crucial for improving diagnosis, treatment, and prognosis.It manifests through symptoms like weakness, fatigue, pale skin, and shortness of breath due to insufficient hemoglobin or red blood cells to carry adequate oxygen, with severe cases leading to complications such as chest pain. …”
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Serological characteristics and immunohematological difficulties in autoimmune hemolytic anemia patients: A retrospective analytical study from South India by Dibyajyoti Sahoo, S. Anuragaa

“…INTRODUCTION: Autoimmune hemolytic anemia (AIHA) is a condition in which there is decreased survival of red blood cells (RBC) due to the destruction of RBC by autoantibodies. …”
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A 34-Week Size Uterus with a Complete Hydatidiform Mole: Hook Effect and Severe Anemia with No Vaginal Bleeding by Rodney McLaren, Vijaya Bayya, Mohamad Irani

“…Therefore, complete mole can present with symptoms related to an enlarged uterus and severe anemia before the occurrence of vaginal bleeding. …”
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Comparison of Birth Weights of Pre-Delivery Anemic and Non-Anemic Routine Iron Supplemented Pregnant Women by Tolga Atakul

“…Mean values for hemoglobin, hematocrit, mean corpuscular volume, red blood cell count and red cell distribution width were as follows; 10.9g/dL (±1.4), 34.6 % (±4.3), 84.6fL (±7.8), 4.1g/dL (±0.4), and 14.2 % (±2.5), respectively. …”
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Risk of hereditary spherocytosis misdiagnosis due to limited effective diagnostic methods by Hien Thanh Dao, Triet Hy Van, Tuyet Thi Bach Tran, Dat Quoc Ngo, Anh Thi Mai Nguyen

“…This assay should be considered a frontline test for diagnosing hereditary spherocytosis in patients with hemolytic anemia. …”
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Study Comparison between Alcoholic Extract of Broccoli, Folic Acid and Ferrous Sulfate Against Damage of the Cardiovascular System Induced by Lead-acetate in Rabbits by Dina S Dheyab, Jawad K Arrak, Majida A J Al-Qayim

“… Anemia is a most common blood disorder that contributes to Cardiovascular diseases. …”
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Case report: Suspected propofol associated Heinz body anemia in five mechanically ventilated dogs: a historical case series by Emily M. Ireland, Claire R. Sharp, Ellie M. Leister, Susan Boyd

“…ObjectiveThe aim of this report is to raise awareness of the risk of oxidant-induced erythrocyte injury, including Heinz body (HB) anemia, in critically ill dogs by describing the condition in five dogs receiving constant rate infusions of propofol.Case summaryThis case series describes five dogs with suspected propofol-induced HB anemia undergoing mechanical ventilation (MV) for lower motor neuron disease. …”
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Oral administration of ethanol extract from Gynura procumbens stems corrects kidney injury and renal anemia in chronic kidney disease by Ting-Ting Li, Li-Ying Wen, Sha-Sha Meng, Yu-Sang Li, He-Bin Tang

“…An adenine-induced rat CKD model was used to elucidate the effective mechanism of EEGS and selected metabolites to correct renal anemia.ResultsThe results showed that treatment with EEGS reversed abnormal changes in the blood indicators, including hemoglobin, red blood cells, serum erythropoietin (EPO), and creatinine levels. …”
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The Role of Inspiratory Muscle Training in Sickle Cell Anemia Related Pulmonary Damage due to Recurrent Acute Chest Syndrome Attacks by Burcu Camcıoğlu, Meral Boşnak-Güçlü, Müşerrefe Nur Karadallı, Şahika Zeynep Akı, Gülsan Türköz-Sucak

“…Background. The sickling of red blood cells causes a constellation of musculoskeletal, cardiovascular, and pulmonary manifestations. …”
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Treatment Inertia and Symptom Burden in Anemia of CKD: Insights from the SATISFY Survey in the Middle East, South Africa, and Türkiye by Arici M, Al-Ghamdi SMG, Assounga AG, El-Koraie AF, McMillan A, Camidge LJ, Sumarsono B, Blogg M, Ng DB, Lansang EP

“…Improved awareness of this disagreement may help facilitate physician–patient dialogue to improve patient experience.Plain Language Summary: A survey to understand the experiences of people living with anemia and kidney disease in the Middle East, South Africa, and TürkiyeBackgroundPeople living with kidney disease can have a low number of red blood cells (anemia).This can cause heart problems, make kidney disease worse, and lead to death.Not much is known about the experiences of people living with kidney disease and anemia in the Middle East, South Africa, and Türkiye.For example, what symptoms do they experience, and which treatments do they receive for their anemia?…”
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The Association between Standardized Serum 25-Hydroxyvitamin D Concentration and Risk of Anemia: A Population-Based Cross-Sectional Study by Yang Zhang, Xiaotong Wang, Jia Wang, Weiwei Hu, Xiaolu Song, Ding Yuan, Xianliang Yan

“…A generalized linear model and restricted cubic spline (RCS) plot curve were constructed to assess the relationship between serum 25(OH)D concentration and anemia incidence. Additionally, the association between serum 25(OH)D concentration and red blood cell (RBC) count and hemoglobin (HB) levels was investigated using generalized additive models with smooth functions. …”
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Establishment of a Comprehensive Platform for Sustained Delivery of Yoga Therapy for Sickle Cell Anemia in Rural and Remote Tribal Pocket in India by Thota Neeraja, Ramesh Nanjundaiah Mavathur, Himanshu Anirudhbhai Shukla, Manmath Gharote

“…Background: Sickle cell anemia (SCA) is the most common inherited genetic red blood cell disorder, highly prevalent in the tribal population residing in the Central India. …”
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Antianemic Treatment of Cancer Patients in German Routine Practice: Data from a Prospective Cohort Study—The Tumor Anemia Registry by Tilman Steinmetz, Jan Schröder, Margarete Plath, Hartmut Link, Michèle Vogt, Melanie Frank, Norbert Marschner

“…Our data suggest that in routine practice diagnostics for treatable causes of anemia are underused. A high proportion of cancer patients receive RBCTx. …”
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Autoimmune Hemolytic Anemia Associated with Mature Ovarian Cystic Teratoma Containing Monoclonal Immunoglobulin G: A Case Report and Review of Literature by Yuma Nato, Keiki Nagaharu, Keika Itoh, Naoki Shinke, Keiko Maeyama, Akihiko Sawaki, Hiroyuki Miyashita

“…Here, we report a successfully treated case of secondary AIHA in a mature cystic teratoma containing antibodies against red blood cells. Case description. A 22-year-old woman was referred to our hospital with progressive anemia. …”
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Limited Exchange Transfusion Can Be Very Beneficial in Sickle Cell Anemia with Acute Chest Syndrome: A Case Report from Tanzania by Clara Chamba, Hamisa Iddy, Erius Tebuka, Furahini Tluway, Elisha Osati, Neema Budodi, Collins Meda, Mbonea Yonazi, Anna Schuh, Lucio Luzzatto, Julie Makani

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Challenges in the diagnosis and management of autoimmune hemolytic anemia: A case-based approach. Experience from a tertiary care hospital in the Haryana region by Geetika Sharma, Shilpi More, Saroj Rajput, Nimisha Sharma, Sonu Choudhary, Tathagata Chatterjee

“…Background: Autoimmune hemolytic anemia (AIHA) is a rare immune disorder which occurs when antibodies are directed against self red blood cells (RBCs) leading to hemolysis. …”
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CALR ins5-mediated clonal hematopoiesis causes severe hemolytic anemia in a female PGK1 Ser320Asn carrier by M. L. Morales, H. Cano, B. de la Morena-Barrio, J. L. Vives-Corrons, E. J. Cuenca-Zamora, P. Garrido-Rodríguez, C. Bento, J. Pereira, J. Martínez Nieto, T. H. Chen-Liang, J. L. Fuster, S. Caracena, M. L. Lozano, R. Teruel-Montoya, J. Corral, F. Ferrer-Marín

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Overview of preclinical and phase II clinical studies on Pegmolesatide’s long-term erythropoiesis stimulating effect via EPOR-mediated signal transduction by Xiaoying Ma, Zhen Li, Lu Zhang, Hui Qian, Qinkai Chen, Ye Tao, Yunfan Li, Dandan Wang, Zhizhen Hu, Weili Luo, Ping Li, Hai Yu, Changlin Mei, Xueqing Yu, Yuanfeng Zhou

“…Abstract Introduction Anemia is a prevalent complication of chronic kidney disease (CKD), primarily due to insufficient erythropoietin (EPO). …”
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Ferric Carboxymaltose in the Management of Iron Deficiency Anemia in Pregnancy: A Subgroup Analysis of a Multicenter Real-World Study Involving 1191 Pregnant Women by Prakash Trivedi, S. Chitra, Suma Natarajan, Vandana Amin, Shilpi Sud, Priti Vyas, Meenakshi Singla, Ajinkya Rodge, Onkar C. Swami

“…Real-world evidence of the efficacy and safety of ferric carboxymaltose (FCM) infusion in Indian pregnant women with iron deficiency anemia (IDA) is lacking. Objective. To assess the efficacy and safety of intravenous (IV) FCM in Indian pregnant women with IDA in 4 weeks in a real-life scenario. …”
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