Relationship of serum total cholesterol and triglyceride with risk of mortality in maintenance hemodialysis patients: a multicenter prospective cohort study by Yan Huang, Qiuxia Zhong, Junzhi Chen, Xianhui Qin, Yaya Yang, Yanhuan He, Zizhen Lin, Yumin Li, Shenglin Yang, Yongxin Lu, Yanhong Zhao, Yaozhong Kong, Qijun Wan, Qi Wang, Sheng Huang, Yan Liu, Aiqun Liu, Fanna Liu, Fanfan Hou, Min Liang

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Effectiveness of an electronic clinical decision support system in improving the management of childhood illness in primary care in rural Nigeria: an observational study by Marek Kwiatkowski, Rodolfo Rossi, Torsten Schmitz, Fenella Beynon, Capucine Musard, Marco Landi, Daniel Ishaya, Jeremiah Zira, Muazu Muazu, Camille Renner, Edwin Emmanuel, Solomon Gideon Bulus

“…Objectives To evaluate the impact of ALgorithm for the MANAgement of CHildhood illness (‘ALMANACH’), a digital clinical decision support system (CDSS) based on the Integrated Management of Childhood Illness, on health and quality of care outcomes for sick children attending primary healthcare (PHC) facilities.Design Observational study, comparing outcomes of children attending facilities implementing ALMANACH with control facilities not yet implementing ALMANACH.Setting PHC facilities in Adamawa State, North-Eastern Nigeria.Participants Children 2–59 months presenting with an acute illness. …”
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Study on influencing factors of age-adjusted Charlson comorbidity index in patients with Alzheimer's disease based on machine learning model by Jian Ding, Jian Ding, Zheng Long, Yiming Liu, Min Wang

“…The age adjusted Charlson Comorbidity Index (aCCI) is an important clinical tool for measuring the burden of comorbidities in patients, closely related to mortality and prognosis. This study aims to use the MIMIC-V database and various regression and machine learning models to screen and validate features closely related to aCCI, providing a theoretical basis for personalized management of AD patients.MethodsThe research data is sourced from the MIMIC-V database, which contains detailed clinical information of AD patients. …”
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Analysis of Role of Haematological Parameters in Diagnosis of Grampositive and Gram-negative Urinary Tract Infection: A Case-control Study by Sudha Srinivasan, Ayeesha Sithika Thajudeen, Kundhavai Chandrasekaran, Vijayashree Raghavan, D Roshini

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Identifying key signs of motor neurone disease in primary care: a nested case–control study using the QResearch database by Aleksandar Radunović, Carol Coupland, Julia Hippisley-Cox, Christopher J McDermott, Tom A Ranger, Judith Burchardt, Xue W Mei

“…Among those from the Red Flag tool, dysarthria had the strongest association with subsequent MND (adjusted OR (aOR): 43.2 (95% CI 36.0 to 52.0)) followed by muscle fasciculations (aOR: 40.2 (95% CI 25.6 to 63.1)) and muscle wasting (aOR: 31.0 (95% CI 19.5 to 49.4)). …”
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A study of introduced apple cultivars according to the main components of winter hardiness by simulating damaging factors under controlled conditions by А. M. Galasheva, N. G. Krasova, Z. E. Ozherelieva

“…One-year-old branches were frozen in a Japanese Espec PSL-2KPH climate chamber after prehardening under –5°C and –10°C for 5 days, and damaging factors of the winter period were simulated.Results. …”
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Impact of aspirin on biochemical recurrence of prostate cancer after robot assisted radical prostatectomy in a multicenter retrospective cohort study by Shuhei Suzuki, Hiromitsu Negoro, Masashi Kubota, Takayuki Sumiyoshi, Ryoichi Saito, Tomoya Okuno, Takehiko Segawa, Shigeki Fukuzawa, Hiroyuki Onishi, Kodai Hattahara, Kanji Nagahama, Yuya Sekine, Ryoma Kurahashi, Kimihiro Shimatani, Atsuro Sawada, Shusuke Akamatsu, Hiroyuki Nishiyama, Takayuki Goto, Takashi Kobayashi

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The Association between Standardized Serum 25-Hydroxyvitamin D Concentration and Risk of Anemia: A Population-Based Cross-Sectional Study by Yang Zhang, Xiaotong Wang, Jia Wang, Weiwei Hu, Xiaolu Song, Ding Yuan, Xianliang Yan

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Antianemic Treatment of Cancer Patients in German Routine Practice: Data from a Prospective Cohort Study—The Tumor Anemia Registry by Tilman Steinmetz, Jan Schröder, Margarete Plath, Hartmut Link, Michèle Vogt, Melanie Frank, Norbert Marschner

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Spectroscopic (FT-IR and FT-Raman) and quantum chemical study on monomer and dimer of benznidazole from DFT and molecular docking approaches by Tirth Raj Paneru, Manoj Kumar Chaudhary, Poonam Tandon, Bhawani Datt Joshi, Beatriz Pinheiro Bezerra, Alejandro Pedro Ayala

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Measurement of Capsaicinoids in Chiltepin Hot Pepper: A Comparison Study between Spectrophotometric Method and High Performance Liquid Chromatography Analysis by Alberto González-Zamora, Erick Sierra-Campos, Rebeca Pérez-Morales, Cirilo Vázquez-Vázquez, Miguel A. Gallegos-Robles, José D. López-Martínez, José L. García-Hernández

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Early prediction of in-hospital mortality in patients with congestive heart failure in intensive care unit: a retrospective observational cohort study by Tao Huang, Rui Yang, Jun Lyu, Didi Han, Fengshuo Xu, Shuai Zheng, Luming Zhang, Haiyan Yin

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Circulatory Immune Cells in Cushing Syndrome: Bystanders or Active Contributors to Atherometabolic Injury? A Study of Adhesion and Activation of Cell Surface Markers by Gloria Aranda, Cristina Lopez, Rebeca Fernandez-Ruiz, Yaiza Esteban, Guillermo Garcia-Eguren, Mireia Mora, Irene Halperin, Gregori Casals, Joaquim Enseñat, Felicia A. Hanzu

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Prevalence of Computer Vision Syndrome and Associated Factors among Instructors in Ethiopian Universities: A Web-Based Cross-Sectional Study by Demisu Zenbaba, Biniyam Sahiledengle, Mitiku Bonsa, Yohannes Tekalegn, Jember Azanaw, Vijay Kumar Chattu

“…Of the total 416 participants, about 293 (70.4%) were reported to have CVS (95% CI: 65.9–74.5%), of which 54.6% were aged 24–33 years. Blurred vision, pain in and around the eye, and eye redness were the main symptoms reported. …”
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Factors associated with prolonged length of stay following cardiac surgery in a major referral hospital in Oman: a retrospective observational study by Paul Aylin, Ahmed Almashrafi, Hilal Alsabti, Mirdavron Mukaddirov, Baskaran Balan

“…The second was to devise a predictive model for prolonged LOS in the cardiac intensive care unit (CICU) based on preoperative factors available at admission and to compare it against two existing cardiac stratification systems.Design Observational retrospective study.Settings A tertiary hospital in Oman.Participants All adult patients who underwent cardiac surgery at a major referral hospital in Oman between 2009 and 2013.Results 30.5% of the patients had prolonged LOS (≥11 days) after surgery, while 17% experienced prolonged ICU LOS (≥5 days). …”
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Central Venous-to-Arterial CO2 Gap Is a Useful Parameter in Monitoring Hypovolemia-Caused Altered Oxygen Balance: Animal Study by Szilvia Kocsi, Gabor Demeter, Daniel Erces, Eniko Nagy, Jozsef Kaszaki, Zsolt Molnar

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Efficacy of Prophylactic Cerclage in Women with a Single History of Mid-Trimester Pregnancy Loss with Painless Cervical Dilation: A Retrospective Cohort Study by Atsuko Tezuka, Hiroyuki Tsuda, Yumiko Ito, Tomoko Ando

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Evaluation of a peer support group programme for vulnerable host population and refugees living with diabetes and/or hypertension in Lebanon: a before-after study by Leah Anku Sanga, Carla Njeim, Éimhín Ansbro, Rima Kighsro Naimi, Ali Ibrahim, Benjamin Schmid, Jasmin Lilian Diab, Jytte Roswall, Tim Clayton, Lars Bruun Larsen, Pablo Perel

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Efficacy Study of Carrageenan as an Alternative Infused Material (Filler) in Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Porous 3D Scaffold by Nor Syamimi Che Johari, Syazwan Aizad, Saiful Irwan Zubairi

“…Therefore, this research attempts to overcome the weaknesses by using carrageenan from red seaweed Kappaphycus alvarezii as an alternative infused material (filler) of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) porous 3D scaffold. …”
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An In Vitro Pilot Study Comparing the Novel HemoClear Gravity-Driven Microfiltration Cell Salvage System with the Conventional Centrifugal XTRA™ Autotransfusion Device by Anneloes Hoetink, Sabine F. Scherphof, Frederik J. Mooi, Paul Westers, Jack van Dijk, Sjef J. van de Leur, Arno P. Nierich

“…In 2013, the World Health Organization reported a shortage of 17 million red blood cell units, a number that remains growing. …”
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