Proximal tubular RAGE mediated the renal fibrosis in UUO model mice via upregulation of autophagy by Bohao Liu, Tianshi Sun, Huiling Li, Shuangfa Qiu, Yijian Li, Dongshan Zhang

“…Furthermore, PT-RAGE-KO mice reduced kidney fibrosis in UUO model via inhibiting Stat3/Atg7 axis by knocking down RAGE. …”
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« Bois ! ». La rencontre fatale entre Salammbô et Mâtho dans les transpositions iconiques du roman by Bruna Donatelli

“…The encounter between Salammbô and Mâtho, the two main characters in Flaubert’s Carthaginian novel, is marked by a daring gesture by Hamilcar Barca’s daughter which will ultimately cost both of them their lives. …”
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La pensée de Gorz : un modèle social et politique possible dans et en dehors de l’école à l’ère du changement climatique ? by Céline Chauvigné

“…Through his radical thinking, he proposed ways of defending "the lived world" in the face of the climate catastrophe that has been raging since the 1960s. How can this avant-garde figure inspire young people in and out of school to think about, preserve and imagine life on Earth today? …”
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Sevoflurane Exacerbates Cognitive Impairment Induced by Aβ1–40 in Rats through Initiating Neurotoxicity, Neuroinflammation, and Neuronal Apoptosis in Rat Hippocampus by Yue Tian, Ke-yan Chen, Li-dan Liu, Yun-xia Dong, Ping Zhao, Shan-bin Guo

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Ishophloroglucin A Isolated from <i>Ishige okamurae</i> Protects Glomerular Cells from Methylglyoxal-Induced Diacarbonyl Stress and Inhibits the Pathogenesis of Diabetic Nephropath... by Chi-Heung Cho, Min-Gyeong Kim, Bomi Ryu, Sang-Hoon Lee

“…We evaluated its anti-glycation ability, intracellular reactive oxygen species scavenging activity, inhibitory effect on the accumulation of intracellular MGO/MGO-derived advanced glycation end products (AGE), and regulation of downstream signaling pathways related to the AGE–receptor for AGEs (RAGE) interaction. IPA (0.2, 1, and 5 μM) demonstrated anti-glycation ability by inhibiting the formation of glucose-fructose-BSA-derived AGEs by up to 54.63% compared to the untreated control, reducing the formation of irreversible cross-links between MGO-derived AGEs and collagen by 67.68% and the breaking down of existing cross-links by approximately 91% (<i>p</i> < 0.001). …”
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Influencing Factors and Clustering Characteristics of COVID-19: A Global Analysis by Tianlong Zheng, Chunli Zhang, Yueting Shi, Debao Chen, Sheng Liu

“…The unprecedented coronavirus disease 2019 (COVID-19) pandemic is still raging (in year 2021) in many countries worldwide. …”
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Protective effect of adiponectin on oxidative stress-induced ovarian granulosa cell senescence in geese by Yan Zheng, Yunqiao Qiu, Ming Gao, Qianhui Wang, Lei Yu, Zhongzan Cao, Xinhong Luan

“…To investigate this, senescence in primary goose GCs was induced by D-gal and assessed via RT‒qPCR, senescence-associated β-galactosidase (SA-β-gal) staining, immunofluorescence, flow cytometry, and transcriptomics. The effect of ADPN on GC senescence was investigated by overexpressing and knocking down ADPN expression. …”
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Wartime activities of the Vavilov Institute by I. G. Loskutov

“…In the harsh reality of the winter in 1941–1942, the daily bread rationing was cut down, and hunger raged in the city, killing tens of thousands of city residents, including VIR employees who kept the stored seeds and tubers untouched. …”
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