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    Association between phase angle and daily creatinine excretion changes in critically ill patients: an approach to muscle mass by Patricio Vargas-Errázuriz, Patricio Vargas-Errázuriz, Natalia Dreyse, Natalia Dreyse, Natalia Dreyse, René López, René López, Marcelo Cano-Cappellacci, Jerónimo Graf, Julia Guerrero, Julia Guerrero

    Published 2025-01-01
    “…This retrospective cohort study explores the potential of phase angle (PA°) derived from bioelectrical impedance analysis (BIA) as a surrogate marker for muscle mass monitoring by associating it with daily creatinine excretion (DCE), a structural and metabolic muscle mass marker. …”
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    Gene-editing in patient and humanized-mice primary muscle stem cells rescues dysferlin expression in dysferlin-deficient muscular dystrophy by Helena Escobar, Silvia Di Francescantonio, Julia Smirnova, Robin Graf, Stefanie Müthel, Andreas Marg, Alexej Zhogov, Supriya Krishna, Eric Metzler, Mina Petkova, Oliver Daumke, Ralf Kühn, Simone Spuler

    Published 2025-01-01
    “…We targeted a frequent loss-of-function, DYSF exon 44, founder frameshift mutation with mRNA-mediated delivery of SpCas9 in combination with a mutation-specific sgRNA to primary muscle stem cells from two homozygous patients. …”
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